Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3375
  Reference Plasmid   MGYG000299035__MGYG000299035_48
  Reference Plasmid Size   3651
  Reference Plasmid GC Content   0.40
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0137718 DPDCAMMH_00004 1792 3 Oral 0.75 protein_coding missense_variant MODERATE 106A>G Lys36Glu
M0137719 DPDCAMMH_00004 1793 3 Oral 0.75 protein_coding synonymous_variant LOW 105C>T Ala35Ala
M0137720 DPDCAMMH_00004 1806 3 Oral 0.75 protein_coding missense_variant MODERATE 92A>T Tyr31Phe
M0137721 DPDCAMMH_00005 2066 3 Oral 0.75 protein_coding synonymous_variant LOW 747T>C Ala249Ala
M0137722 DPDCAMMH_00005 2143 3 Oral 0.75 protein_coding missense_variant MODERATE 670A>G Ile224Val
M0137723 DPDCAMMH_00005 2157 3 Oral 0.75 protein_coding missense_variant MODERATE 656G>A Gly219Glu
M0137724 DPDCAMMH_00005 2158 3 Oral 0.75 protein_coding missense_variant MODERATE 655G>A Gly219Arg
M0137725 DPDCAMMH_00005 2372 3 Oral 0.75 protein_coding synonymous_variant LOW 441T>C Ile147Ile
M0137726 DPDCAMMH_00005 2375 3 Oral 0.75 protein_coding synonymous_variant LOW 438C>T Asp146Asp
M0137727 DPDCAMMH_00005 2678 3 Oral 0.75 protein_coding synonymous_variant LOW 135A>G Val45Val
M0137728 DPDCAMMH_00005 2702 3 Oral 0.75 protein_coding synonymous_variant LOW 111G>T Thr37Thr
M0137729 DPDCAMMH_00005 2726 3 Oral 0.75 protein_coding synonymous_variant LOW 87C>T Tyr29Tyr
M0137730 DPDCAMMH_00005 2727 3 Oral 0.75 protein_coding missense_variant MODERATE 86A>G Tyr29Cys
M0137731 DPDCAMMH_00005 2762 3 Oral 0.75 protein_coding synonymous_variant LOW 51A>C Gly17Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term