Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3378
  Reference Plasmid   MGYG000299059__MGYG000299059_236
  Reference Plasmid Size   8704
  Reference Plasmid GC Content   0.42
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0137753 BFJCEGMG_00001 494 4 Oral 0.57 protein_coding synonymous_variant LOW 783A>C Val261Val
M0137754 BFJCEGMG_00001 509 3 Oral 0.43 protein_coding synonymous_variant LOW 768G>T Ser256Ser
M0137755 BFJCEGMG_00001 551 3 Oral 0.43 protein_coding synonymous_variant LOW 726T>C Tyr242Tyr
M0137756 BFJCEGMG_00001 755 4 Oral 0.57 protein_coding synonymous_variant LOW 522T>C Pro174Pro
M0137757 BFJCEGMG_00001 766 3 Oral 0.43 protein_coding missense_variant MODERATE 511T>C Ser171Pro
M0137758 BFJCEGMG_00001 835 3 Oral 0.43 protein_coding missense_variant MODERATE 442G>A Val148Ile
M0137759 BFJCEGMG_00001 1081 3 Oral 0.43 protein_coding synonymous_variant LOW 196A>C Arg66Arg
M0137760 BFJCEGMG_00001 1109 3 Oral 0.43 protein_coding synonymous_variant LOW 168C>T Arg56Arg
M0137761 BFJCEGMG_00001 1123 3 Oral 0.43 protein_coding missense_variant MODERATE 154G>A Val52Ile
M0137762 BFJCEGMG_00002 1322 3 Oral 0.43 protein_coding missense_variant MODERATE 923A>G Lys308Arg
M0137763 BFJCEGMG_00002 1333 3 Oral 0.43 protein_coding synonymous_variant LOW 912G>A Leu304Leu
M0137764 BFJCEGMG_00002 1336 3 Oral 0.43 protein_coding synonymous_variant LOW 909T>A Leu303Leu
M0137765 BFJCEGMG_00002 1480 5 Oral 0.71 protein_coding synonymous_variant LOW 765T>C Phe255Phe
M0137766 BFJCEGMG_00002 1489 3 Oral 0.43 protein_coding synonymous_variant LOW 756T>C Asn252Asn
M0137767 BFJCEGMG_00002 1516 5 Oral 0.71 protein_coding synonymous_variant LOW 729T>C Asp243Asp
M0137768 BFJCEGMG_00002 1519 3 Oral 0.43 protein_coding synonymous_variant LOW 726C>A Gly242Gly
M0137769 BFJCEGMG_00002 1543 3 Oral 0.43 protein_coding missense_variant MODERATE 702A>T Glu234Asp
M0137770 BFJCEGMG_00002 1582 3 Oral 0.43 protein_coding synonymous_variant LOW 663G>A Thr221Thr
M0137771 BFJCEGMG_00002 1590 3 Oral 0.43 protein_coding missense_variant MODERATE 655C>A Gln219Lys
M0137772 BFJCEGMG_00002 1594 5 Oral 0.71 protein_coding synonymous_variant LOW 651A>G Lys217Lys
M0137773 BFJCEGMG_00002 1597 3 Oral 0.43 protein_coding synonymous_variant LOW 648C>T Asp216Asp
M0137774 BFJCEGMG_00002 1600 3 Oral 0.43 protein_coding synonymous_variant LOW 645C>A Ala215Ala
M0137775 BFJCEGMG_00002 1650 3 Oral 0.43 protein_coding missense_variant MODERATE 595A>C Asn199His
M0137776 BFJCEGMG_00002 1722 4 Oral 0.57 protein_coding missense_variant MODERATE 523T>G Ser175Ala
M0137777 BFJCEGMG_00002 1780 5 Oral 0.71 protein_coding synonymous_variant LOW 465G>T Val155Val
M0137778 BFJCEGMG_00002 1843 4 Oral 0.57 protein_coding synonymous_variant LOW 402T>C Arg134Arg
M0137779 BFJCEGMG_00002 1906 4 Oral 0.57 protein_coding synonymous_variant LOW 339C>T Phe113Phe
M0137780 BFJCEGMG_00002 1951 5 Oral 0.71 protein_coding synonymous_variant LOW 294G>A Gly98Gly
M0137781 BFJCEGMG_00002 2014 4 Oral 0.57 protein_coding synonymous_variant LOW 231T>C Thr77Thr
M0137782 BFJCEGMG_00002 2020 4 Oral 0.57 protein_coding synonymous_variant LOW 225T>A Ala75Ala
M0137783 BFJCEGMG_00002 2041 5 Oral 0.71 protein_coding synonymous_variant LOW 204C>T Tyr68Tyr
M0137784 BFJCEGMG_00002 2044 4 Oral 0.57 protein_coding synonymous_variant LOW 201A>C Arg67Arg
M0137785 BFJCEGMG_00002 2050 4 Oral 0.57 protein_coding synonymous_variant LOW 195C>T Phe65Phe
M0137786 BFJCEGMG_00002 2080 4 Oral 0.57 protein_coding synonymous_variant LOW 165T>C Val55Val
M0137787 BFJCEGMG_00002 2081 4 Oral 0.57 protein_coding missense_variant MODERATE 164T>C Val55Ala
M0137788 BFJCEGMG_00002 2082 4 Oral 0.57 protein_coding missense_variant MODERATE 163G>A Val55Ile
M0137789 BFJCEGMG_00002 2140 3 Oral 0.43 protein_coding synonymous_variant LOW 105G>A Gln35Gln
M0137790 BFJCEGMG_00002 2173 4 Oral 0.57 protein_coding synonymous_variant LOW 72C>A Ile24Ile
M0137791 BFJCEGMG_00001 2291 4 Oral 0.57 protein_coding upstream_gene_variant MODIFIER -1015T>C None
M0137792 BFJCEGMG_00001 2321 5 Oral 0.71 protein_coding upstream_gene_variant MODIFIER -1045C>T None
M0137793 BFJCEGMG_00001 2407 4 Oral 0.57 protein_coding upstream_gene_variant MODIFIER -1131C>T None
M0137794 BFJCEGMG_00001 2613 3 Oral 0.43 protein_coding upstream_gene_variant MODIFIER -1337T>G None
M0137795 BFJCEGMG_00003 2762 3 Oral 0.43 protein_coding synonymous_variant LOW 1446A>G Lys482Lys
M0137796 BFJCEGMG_00003 2780 3 Oral 0.43 protein_coding synonymous_variant LOW 1428T>C Leu476Leu
M0137797 BFJCEGMG_00003 2844 4 Oral 0.57 protein_coding missense_variant MODERATE 1364A>C Glu455Ala
M0137798 BFJCEGMG_00003 3089 5 Oral 0.71 protein_coding synonymous_variant LOW 1119T>C Phe373Phe
M0137799 BFJCEGMG_00003 3186 4 Oral 0.57 protein_coding missense_variant MODERATE 1022T>A Val341Glu
M0137800 BFJCEGMG_00003 3194 5 Oral 0.71 protein_coding synonymous_variant LOW 1014C>T Asp338Asp
M0137801 BFJCEGMG_00003 3215 4 Oral 0.57 protein_coding synonymous_variant LOW 993T>C Cys331Cys
M0137802 BFJCEGMG_00003 3251 4 Oral 0.57 protein_coding missense_variant MODERATE 957C>G His319Gln
M0137803 BFJCEGMG_00003 4013 5 Oral 0.71 protein_coding synonymous_variant LOW 195A>T Pro65Pro
M0137804 BFJCEGMG_00003 4065 3 Oral 0.43 protein_coding missense_variant MODERATE 143T>C Val48Ala
M0137805 BFJCEGMG_00001 4318 4 Oral 0.57 protein_coding upstream_gene_variant MODIFIER -3042T>A None
M0137806 BFJCEGMG_00004 4370 3 Oral 0.43 protein_coding synonymous_variant LOW 558G>T Pro186Pro
M0137807 BFJCEGMG_00004 4375 3 Oral 0.43 protein_coding missense_variant MODERATE 553A>T Met185Leu
M0137808 BFJCEGMG_00004 4387 3 Oral 0.43 protein_coding missense_variant MODERATE 541A>T Thr181Ser
M0137809 BFJCEGMG_00004 4391 4 Oral 0.57 protein_coding synonymous_variant LOW 537T>A Ala179Ala
M0137810 BFJCEGMG_00004 4397 3 Oral 0.43 protein_coding synonymous_variant LOW 531G>A Pro177Pro
M0137811 BFJCEGMG_00004 4478 5 Oral 0.71 protein_coding synonymous_variant LOW 450T>C Ala150Ala
M0137812 BFJCEGMG_00004 4526 3 Oral 0.43 protein_coding synonymous_variant LOW 402C>T Asp134Asp
M0137813 BFJCEGMG_00004 4604 3 Oral 0.43 protein_coding synonymous_variant LOW 324C>T Asn108Asn
M0137814 BFJCEGMG_00004 4727 4 Oral 0.57 protein_coding synonymous_variant LOW 201A>G Ala67Ala
M0137815 BFJCEGMG_00004 4729 3 Oral 0.43 protein_coding missense_variant MODERATE 199G>T Ala67Ser
M0137816 BFJCEGMG_00004 4750 3 Oral 0.43 protein_coding missense_variant MODERATE 178A>G Thr60Ala
M0137817 BFJCEGMG_00001 4953 5 Oral 0.71 protein_coding upstream_gene_variant MODIFIER -3677C>T None
M0137818 BFJCEGMG_00005 398 3 Oral 0.43 protein_coding upstream_gene_variant MODIFIER -4863A>G None
M0137819 BFJCEGMG_00001 581 4 Oral 0.57 protein_coding synonymous_variant LOW 696T>G Ala232Ala
M0137820 BFJCEGMG_00002 1672 3 Oral 0.43 protein_coding missense_variant MODERATE 573A>T Glu191Asp
M0137821 BFJCEGMG_00001 2326 3 Oral 0.43 protein_coding upstream_gene_variant MODIFIER -1050C>T None
M0137822 BFJCEGMG_00001 2450 4 Oral 0.57 protein_coding upstream_gene_variant MODIFIER -1174G>T None
M0137823 BFJCEGMG_00003 3668 3 Oral 0.43 protein_coding synonymous_variant LOW 540T>C Asn180Asn
M0137824 BFJCEGMG_00004 4861 3 Oral 0.43 protein_coding missense_variant MODERATE 67A>G Ile23Val
M0137825 BFJCEGMG_00005 5482 4 Oral 0.57 protein_coding synonymous_variant LOW 222C>A Thr74Thr
M0137826 BFJCEGMG_00005 5618 4 Oral 0.57 protein_coding missense_variant MODERATE 358C>G Gln120Glu
M0137827 BFJCEGMG_00005 5626 4 Oral 0.57 protein_coding synonymous_variant LOW 366T>G Ala122Ala
M0137828 BFJCEGMG_00005 5627 4 Oral 0.57 protein_coding missense_variant MODERATE 367A>C Asn123His
M0137829 BFJCEGMG_00005 5644 3 Oral 0.43 protein_coding synonymous_variant LOW 384T>C Leu128Leu
M0137830 BFJCEGMG_00005 5821 4 Oral 0.57 protein_coding synonymous_variant LOW 561A>G Lys187Lys
M0137831 BFJCEGMG_00005 5892 4 Oral 0.57 protein_coding missense_variant MODERATE 632T>C Ile211Thr
M0137832 BFJCEGMG_00005 5956 4 Oral 0.57 protein_coding missense_variant MODERATE 696G>A Met232Ile
M0137833 BFJCEGMG_00005 6040 5 Oral 0.71 protein_coding synonymous_variant LOW 780A>G Glu260Glu
M0137834 BFJCEGMG_00005 6121 5 Oral 0.71 protein_coding synonymous_variant LOW 861T>C Gly287Gly
M0137835 BFJCEGMG_00005 6143 5 Oral 0.71 protein_coding missense_variant MODERATE 883G>A Glu295Lys
M0137836 BFJCEGMG_00002 6299 5 Oral 0.71 protein_coding upstream_gene_variant MODIFIER -4055A>G None
M0137837 BFJCEGMG_00002 6350 4 Oral 0.57 protein_coding upstream_gene_variant MODIFIER -4106G>A None
M0137838 BFJCEGMG_00006 6416 3 Oral 0.43 protein_coding synonymous_variant LOW 66G>A Gln22Gln
M0137839 BFJCEGMG_00006 6626 5 Oral 0.71 protein_coding synonymous_variant LOW 276A>G Leu92Leu
M0137840 BFJCEGMG_00006 6635 4 Oral 0.57 protein_coding synonymous_variant LOW 285A>G Thr95Thr
M0137841 BFJCEGMG_00006 6845 3 Oral 0.43 protein_coding synonymous_variant LOW 495C>T Arg165Arg
M0137842 BFJCEGMG_00006 6848 4 Oral 0.57 protein_coding synonymous_variant LOW 498A>G Leu166Leu
M0137843 BFJCEGMG_00006 6908 3 Oral 0.43 protein_coding synonymous_variant LOW 558T>A Ala186Ala
M0137844 BFJCEGMG_00006 6915 3 Oral 0.43 protein_coding synonymous_variant LOW 565C>A Arg189Arg
M0137845 BFJCEGMG_00006 6917 3 Oral 0.43 protein_coding synonymous_variant LOW 567A>G Arg189Arg
M0137846 BFJCEGMG_00006 6972 3 Oral 0.43 protein_coding missense_variant MODERATE 622A>G Thr208Ala
M0137847 BFJCEGMG_00006 7004 4 Oral 0.57 protein_coding synonymous_variant LOW 654A>G Ser218Ser
M0137848 BFJCEGMG_00006 7020 4 Oral 0.57 protein_coding missense_variant MODERATE 670A>C Thr224Pro
M0137849 BFJCEGMG_00006 7021 4 Oral 0.57 protein_coding missense_variant MODERATE 671C>A Thr224Lys
M0137850 BFJCEGMG_00006 7022 4 Oral 0.57 protein_coding synonymous_variant LOW 672G>T Thr224Thr
M0137851 BFJCEGMG_00006 7031 4 Oral 0.57 protein_coding synonymous_variant LOW 681C>T Asp227Asp
M0137852 BFJCEGMG_00006 7181 4 Oral 0.57 protein_coding synonymous_variant LOW 831A>C Ile277Ile
M0137853 BFJCEGMG_00006 7226 4 Oral 0.57 protein_coding synonymous_variant LOW 876C>T Gly292Gly
M0137854 BFJCEGMG_00006 7233 3 Oral 0.43 protein_coding synonymous_variant LOW 883A>C Arg295Arg
M0137855 BFJCEGMG_00006 7250 4 Oral 0.57 protein_coding missense_variant MODERATE 900A>C Leu300Phe
M0137856 BFJCEGMG_00006 7484 4 Oral 0.57 protein_coding synonymous_variant LOW 1134C>T Ala378Ala
M0137857 BFJCEGMG_00006 7688 3 Oral 0.43 protein_coding synonymous_variant LOW 1338T>C Asp446Asp
M0137858 BFJCEGMG_00006 8441 3 Oral 0.43 protein_coding synonymous_variant LOW 2091G>A Pro697Pro
M0137859 BFJCEGMG_00006 8477 3 Oral 0.43 protein_coding synonymous_variant LOW 2127A>C Ala709Ala
M0137860 BFJCEGMG_00003 8563 3 Oral 0.43 protein_coding upstream_gene_variant MODIFIER -4356T>C None
M0137861 BFJCEGMG_00006 6551 3 Oral 0.43 protein_coding synonymous_variant LOW 201T>A Val67Val
M0137862 BFJCEGMG_00006 6782 3 Oral 0.43 protein_coding synonymous_variant LOW 432T>A Val144Val
M0137863 BFJCEGMG_00006 6965 3 Oral 0.43 protein_coding synonymous_variant LOW 615C>T Asn205Asn
M0137864 BFJCEGMG_00006 8150 3 Oral 0.43 protein_coding synonymous_variant LOW 1800C>T Val600Val
M0137865 BFJCEGMG_00001 617 3 Oral 0.43 protein_coding synonymous_variant LOW 660A>G Gly220Gly
M0137866 BFJCEGMG_00003 3164 3 Oral 0.43 protein_coding missense_variant MODERATE 1044T>A Asp348Glu
M0137867 BFJCEGMG_00005 5608 3 Oral 0.43 protein_coding synonymous_variant LOW 348C>A Thr116Thr
M0137868 BFJCEGMG_00005 6088 3 Oral 0.43 protein_coding synonymous_variant LOW 828T>C Arg276Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term