Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3382
  Reference Plasmid   MGYG000299078__MGYG000299078_52
  Reference Plasmid Size   10677
  Reference Plasmid GC Content   0.40
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0138050 GICBOHAF_00002 1215 3 Oral 1.00 protein_coding missense_variant MODERATE 781A>G Ile261Val
M0138051 GICBOHAF_00002 1229 3 Oral 1.00 protein_coding synonymous_variant LOW 795A>T Leu265Leu
M0138052 GICBOHAF_00002 1235 3 Oral 1.00 protein_coding synonymous_variant LOW 801A>T Arg267Arg
M0138053 GICBOHAF_00002 1241 3 Oral 1.00 protein_coding synonymous_variant LOW 807C>T His269His
M0138054 GICBOHAF_00002 1250 3 Oral 1.00 protein_coding synonymous_variant LOW 816T>C Thr272Thr
M0138055 GICBOHAF_00002 1322 3 Oral 1.00 protein_coding synonymous_variant LOW 888C>T His296His
M0138056 GICBOHAF_00002 1328 3 Oral 1.00 protein_coding synonymous_variant LOW 894G>C Thr298Thr
M0138057 GICBOHAF_00002 1335 3 Oral 1.00 protein_coding missense_variant MODERATE 901T>A Ser301Thr
M0138058 GICBOHAF_00002 1436 3 Oral 1.00 protein_coding synonymous_variant LOW 1002T>A Ala334Ala
M0138059 GICBOHAF_00002 1477 3 Oral 1.00 protein_coding missense_variant MODERATE 1043T>C Phe348Ser
M0138060 GICBOHAF_00002 1853 3 Oral 1.00 protein_coding synonymous_variant LOW 1419C>G Ala473Ala
M0138061 GICBOHAF_00002 1985 3 Oral 1.00 protein_coding synonymous_variant LOW 1551T>C Ile517Ile
M0138062 GICBOHAF_00002 1991 3 Oral 1.00 protein_coding synonymous_variant LOW 1557G>A Gln519Gln
M0138063 GICBOHAF_00002 2102 3 Oral 1.00 protein_coding synonymous_variant LOW 1668G>A Lys556Lys
M0138064 GICBOHAF_00004 2449 3 Oral 1.00 protein_coding synonymous_variant LOW 21G>T Leu7Leu
M0138065 GICBOHAF_00004 2500 3 Oral 1.00 protein_coding synonymous_variant LOW 72A>G Leu24Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term