Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3387
  Reference Plasmid   MGYG000299177__MGYG000299177_50
  Reference Plasmid Size   38689
  Reference Plasmid GC Content   0.26
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0139740 MJPAOICF_00008 8820 3 Oral 0.14 protein_coding synonymous_variant LOW 75G>A Gln25Gln
M0139741 MJPAOICF_00008 8826 3 Oral 0.14 protein_coding synonymous_variant LOW 69G>A Gly23Gly
M0139742 MJPAOICF_00008 8851 3 Oral 0.14 protein_coding missense_variant MODERATE 44C>G Ala15Gly
M0139743 MJPAOICF_00038 31802 4 Oral 0.19 protein_coding synonymous_variant LOW 2310C>T Asp770Asp
M0139744 MJPAOICF_00038 31817 4 Oral 0.19 protein_coding synonymous_variant LOW 2295C>A Ser765Ser
M0139745 MJPAOICF_00038 32039 4 Oral 0.19 protein_coding synonymous_variant LOW 2073T>C Asn691Asn
M0139746 MJPAOICF_00038 32096 4 Oral 0.19 protein_coding synonymous_variant LOW 2016C>T Phe672Phe
M0139747 MJPAOICF_00038 32102 4 Oral 0.19 protein_coding missense_variant MODERATE 2010T>G Asp670Glu
M0139748 MJPAOICF_00038 32150 4 Oral 0.19 protein_coding synonymous_variant LOW 1962T>C Asn654Asn
M0139749 MJPAOICF_00038 32180 4 Oral 0.19 protein_coding synonymous_variant LOW 1932T>C Phe644Phe
M0139750 MJPAOICF_00038 32202 4 Oral 0.19 protein_coding missense_variant MODERATE 1910T>A Val637Glu
M0139751 MJPAOICF_00038 32339 3 Oral 0.14 protein_coding synonymous_variant LOW 1773T>C Tyr591Tyr
M0139752 MJPAOICF_00038 32507 3 Oral 0.14 protein_coding synonymous_variant LOW 1605C>T Asn535Asn
M0139753 MJPAOICF_00038 32605 3 Oral 0.14 protein_coding synonymous_variant LOW 1507T>C Leu503Leu
M0139754 MJPAOICF_00038 32618 3 Oral 0.14 protein_coding synonymous_variant LOW 1494T>A Ser498Ser
M0139755 MJPAOICF_00038 32627 3 Oral 0.14 protein_coding synonymous_variant LOW 1485A>G Arg495Arg
M0139756 MJPAOICF_00038 32681 3 Oral 0.14 protein_coding synonymous_variant LOW 1431T>C Tyr477Tyr
M0139757 MJPAOICF_00038 32758 3 Oral 0.14 protein_coding missense_variant MODERATE 1354G>C Val452Leu
M0139758 MJPAOICF_00038 33194 3 Oral 0.14 protein_coding synonymous_variant LOW 918C>T Val306Val
M0139759 MJPAOICF_00038 33339 3 Oral 0.14 protein_coding missense_variant MODERATE 773G>A Gly258Glu
M0139760 MJPAOICF_00038 33363 3 Oral 0.14 protein_coding missense_variant MODERATE 749G>A Ser250Asn
M0139761 MJPAOICF_00038 33368 3 Oral 0.14 protein_coding synonymous_variant LOW 744C>T Phe248Phe
M0139762 MJPAOICF_00038 33383 3 Oral 0.14 protein_coding synonymous_variant LOW 729T>C Asn243Asn
M0139763 MJPAOICF_00038 33422 3 Oral 0.14 protein_coding synonymous_variant LOW 690C>T Ile230Ile
M0139764 MJPAOICF_00038 33482 3 Oral 0.14 protein_coding synonymous_variant LOW 630G>A Glu210Glu
M0139765 MJPAOICF_00038 33518 3 Oral 0.14 protein_coding synonymous_variant LOW 594A>G Val198Val
M0139766 MJPAOICF_00038 33587 3 Oral 0.14 protein_coding synonymous_variant LOW 525T>C Ile175Ile
M0139767 MJPAOICF_00020 16923 3 Oral 0.14 protein_coding synonymous_variant LOW 231C>T Asn77Asn
M0139768 MJPAOICF_00020 16953 3 Oral 0.14 protein_coding synonymous_variant LOW 201T>C Asn67Asn
M0139769 MJPAOICF_00020 16959 3 Oral 0.14 protein_coding synonymous_variant LOW 195A>G Arg65Arg
M0139770 MJPAOICF_00020 16980 3 Oral 0.14 protein_coding synonymous_variant LOW 174A>G Glu58Glu
M0139771 MJPAOICF_00020 16994 3 Oral 0.14 protein_coding missense_variant MODERATE 160A>G Lys54Glu
M0139772 MJPAOICF_00020 17000 3 Oral 0.14 protein_coding missense_variant MODERATE 154G>A Asp52Asn
M0139773 MJPAOICF_00010 10253 3 Oral 0.14 protein_coding synonymous_variant LOW 699T>C Tyr233Tyr
M0139774 MJPAOICF_00010 10844 4 Oral 0.19 protein_coding synonymous_variant LOW 108T>C Ser36Ser
M0139775 MJPAOICF_00011 11098 3 Oral 0.14 protein_coding synonymous_variant LOW 570C>T Ser190Ser
M0139776 MJPAOICF_00011 11101 3 Oral 0.14 protein_coding synonymous_variant LOW 567T>C Gly189Gly
M0139777 MJPAOICF_00011 11233 3 Oral 0.14 protein_coding synonymous_variant LOW 435T>C Ser145Ser
M0139778 MJPAOICF_00011 11279 3 Oral 0.14 protein_coding missense_variant MODERATE 389A>G Lys130Arg
M0139779 MJPAOICF_00011 11293 3 Oral 0.14 protein_coding synonymous_variant LOW 375C>T Tyr125Tyr
M0139780 MJPAOICF_00011 11296 3 Oral 0.14 protein_coding synonymous_variant LOW 372A>C Thr124Thr
M0139781 MJPAOICF_00011 11324 3 Oral 0.14 protein_coding missense_variant MODERATE 344G>A Arg115His
M0139782 MJPAOICF_00011 11338 3 Oral 0.14 protein_coding synonymous_variant LOW 330T>C Phe110Phe
M0139783 MJPAOICF_00011 11377 3 Oral 0.14 protein_coding synonymous_variant LOW 291G>A Val97Val
M0139784 MJPAOICF_00011 11386 3 Oral 0.14 protein_coding synonymous_variant LOW 282C>T Val94Val
M0139785 MJPAOICF_00011 11389 3 Oral 0.14 protein_coding synonymous_variant LOW 279G>A Gln93Gln
M0139786 MJPAOICF_00011 11434 3 Oral 0.14 protein_coding synonymous_variant LOW 234G>A Val78Val
M0139787 MJPAOICF_00011 11457 3 Oral 0.14 protein_coding synonymous_variant LOW 211C>T Leu71Leu
M0139788 MJPAOICF_00011 11491 3 Oral 0.14 protein_coding synonymous_variant LOW 177G>A Leu59Leu
M0139789 MJPAOICF_00011 11511 3 Oral 0.14 protein_coding synonymous_variant LOW 157C>T Leu53Leu
M0139790 MJPAOICF_00011 11589 3 Oral 0.14 protein_coding missense_variant MODERATE 79A>G Asn27Asp
M0139791 MJPAOICF_00038 31408 3 Oral 0.14 protein_coding missense_variant MODERATE 2704G>A Val902Ile
M0139792 MJPAOICF_00038 31421 3 Oral 0.14 protein_coding synonymous_variant LOW 2691T>A Ile897Ile
M0139793 MJPAOICF_00038 31424 3 Oral 0.14 protein_coding synonymous_variant LOW 2688G>A Glu896Glu
M0139794 MJPAOICF_00038 31427 3 Oral 0.14 protein_coding synonymous_variant LOW 2685A>G Lys895Lys
M0139795 MJPAOICF_00038 31436 3 Oral 0.14 protein_coding synonymous_variant LOW 2676A>G Lys892Lys
M0139796 MJPAOICF_00038 31462 3 Oral 0.14 protein_coding missense_variant MODERATE 2650T>C Ser884Pro
M0139797 MJPAOICF_00038 31514 3 Oral 0.14 protein_coding synonymous_variant LOW 2598A>C Thr866Thr
M0139798 MJPAOICF_00038 31523 3 Oral 0.14 protein_coding synonymous_variant LOW 2589A>T Val863Val
M0139799 MJPAOICF_00038 31533 3 Oral 0.14 protein_coding missense_variant MODERATE 2579T>C Val860Ala
M0139800 MJPAOICF_00038 31548 3 Oral 0.14 protein_coding missense_variant MODERATE 2564T>A Phe855Tyr
M0139801 MJPAOICF_00038 31556 3 Oral 0.14 protein_coding synonymous_variant LOW 2556G>A Val852Val
M0139802 MJPAOICF_00038 31625 3 Oral 0.14 protein_coding synonymous_variant LOW 2487T>C Leu829Leu
M0139803 MJPAOICF_00038 31658 3 Oral 0.14 protein_coding synonymous_variant LOW 2454G>A Glu818Glu
M0139804 MJPAOICF_00038 31662 3 Oral 0.14 protein_coding missense_variant MODERATE 2450G>A Arg817Lys
M0139805 MJPAOICF_00038 31679 3 Oral 0.14 protein_coding missense_variant MODERATE 2433T>A Asp811Glu
M0139806 MJPAOICF_00038 31700 3 Oral 0.14 protein_coding synonymous_variant LOW 2412A>G Glu804Glu
M0139807 MJPAOICF_00038 31738 3 Oral 0.14 protein_coding synonymous_variant LOW 2374T>C Leu792Leu
M0139808 MJPAOICF_00038 31748 3 Oral 0.14 protein_coding synonymous_variant LOW 2364G>T Val788Val
M0139809 MJPAOICF_00038 31769 3 Oral 0.14 protein_coding synonymous_variant LOW 2343A>G Ser781Ser
M0139810 MJPAOICF_00038 31829 3 Oral 0.14 protein_coding synonymous_variant LOW 2283C>T Ser761Ser
M0139811 MJPAOICF_00038 31883 3 Oral 0.14 protein_coding synonymous_variant LOW 2229T>C Pro743Pro
M0139812 MJPAOICF_00038 31901 3 Oral 0.14 protein_coding synonymous_variant LOW 2211A>G Glu737Glu
M0139813 MJPAOICF_00038 31940 3 Oral 0.14 protein_coding synonymous_variant LOW 2172T>C Val724Val
M0139814 MJPAOICF_00001 475 3 Oral 0.14 protein_coding missense_variant MODERATE 1046G>A Ser349Asn
M0139815 MJPAOICF_00001 507 3 Oral 0.14 protein_coding synonymous_variant LOW 1014C>T Ala338Ala
M0139816 MJPAOICF_00001 519 3 Oral 0.14 protein_coding synonymous_variant LOW 1002A>G Lys334Lys
M0139817 MJPAOICF_00001 558 3 Oral 0.14 protein_coding synonymous_variant LOW 963C>T Asn321Asn
M0139818 MJPAOICF_00001 579 3 Oral 0.14 protein_coding synonymous_variant LOW 942G>A Gln314Gln
M0139819 MJPAOICF_00001 597 3 Oral 0.14 protein_coding synonymous_variant LOW 924T>C Thr308Thr
M0139820 MJPAOICF_00001 900 3 Oral 0.14 protein_coding synonymous_variant LOW 621C>T Gly207Gly
M0139821 MJPAOICF_00001 1455 3 Oral 0.14 protein_coding synonymous_variant LOW 66A>T Ala22Ala
M0139822 MJPAOICF_00001 1488 3 Oral 0.14 protein_coding synonymous_variant LOW 33C>T Ser11Ser
M0139823 MJPAOICF_00002 1543 3 Oral 0.14 protein_coding synonymous_variant LOW 93G>A Val31Val
M0139824 MJPAOICF_00003 2032 3 Oral 0.14 protein_coding missense_variant MODERATE 481A>G Ile161Val
M0139825 MJPAOICF_00003 2267 3 Oral 0.14 protein_coding synonymous_variant LOW 246T>C Tyr82Tyr
M0139826 MJPAOICF_00003 2444 3 Oral 0.14 protein_coding missense_variant MODERATE 69T>A Asp23Glu
M0139827 MJPAOICF_00003 2455 3 Oral 0.14 protein_coding stop_gained HIGH 58A>T Lys20*
M0139828 MJPAOICF_00003 2465 3 Oral 0.14 protein_coding synonymous_variant LOW 48G>A Lys16Lys
M0139829 MJPAOICF_00003 2488 4 Oral 0.19 protein_coding missense_variant MODERATE 25T>C Tyr9His
M0139830 MJPAOICF_00003 2491 4 Oral 0.19 protein_coding missense_variant MODERATE 22G>A Glu8Lys
M0139831 MJPAOICF_00003 2495 4 Oral 0.19 protein_coding synonymous_variant LOW 18T>C Asn6Asn
M0139832 MJPAOICF_00004 2561 3 Oral 0.14 protein_coding synonymous_variant LOW 2700A>G Lys900Lys
M0139833 MJPAOICF_00004 2588 3 Oral 0.14 protein_coding synonymous_variant LOW 2673G>T Gly891Gly
M0139834 MJPAOICF_00004 2722 3 Oral 0.14 protein_coding synonymous_variant LOW 2539C>T Leu847Leu
M0139835 MJPAOICF_00004 2804 3 Oral 0.14 protein_coding synonymous_variant LOW 2457T>C Asp819Asp
M0139836 MJPAOICF_00004 4235 3 Oral 0.14 protein_coding synonymous_variant LOW 1026T>C Phe342Phe
M0139837 MJPAOICF_00004 4289 3 Oral 0.14 protein_coding synonymous_variant LOW 972C>T Ser324Ser
M0139838 MJPAOICF_00004 4430 3 Oral 0.14 protein_coding synonymous_variant LOW 831C>T Asp277Asp
M0139839 MJPAOICF_00004 4433 3 Oral 0.14 protein_coding synonymous_variant LOW 828T>A Thr276Thr
M0139840 MJPAOICF_00004 4454 3 Oral 0.14 protein_coding synonymous_variant LOW 807G>A Val269Val
M0139841 MJPAOICF_00004 4456 3 Oral 0.14 protein_coding missense_variant MODERATE 805G>A Val269Met
M0139842 MJPAOICF_00004 4590 3 Oral 0.14 protein_coding missense_variant MODERATE 671C>A Thr224Asn
M0139843 MJPAOICF_00004 4750 3 Oral 0.14 protein_coding missense_variant MODERATE 511G>C Glu171Gln
M0139844 MJPAOICF_00006 6074 3 Oral 0.14 protein_coding missense_variant MODERATE 420A>T Arg140Ser
M0139845 MJPAOICF_00006 6143 3 Oral 0.14 protein_coding synonymous_variant LOW 351A>G Leu117Leu
M0139846 MJPAOICF_00007 6727 3 Oral 0.14 protein_coding synonymous_variant LOW 105A>G Gln35Gln
M0139847 MJPAOICF_00008 6884 3 Oral 0.14 protein_coding stop_lost&splice_region_variant HIGH 2011T>A Ter671Lysext*?
M0139848 MJPAOICF_00008 7509 3 Oral 0.14 protein_coding synonymous_variant LOW 1386G>A Ala462Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
MJPAOICF_00003 1.B.93.1.11 84.9 3.2e-123 25 269 0.9108 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.93 The MipA-interacting Protein (MipA) Family