Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3390
  Reference Plasmid   MGYG000299185__MGYG000299185_58
  Reference Plasmid Size   11181
  Reference Plasmid GC Content   0.36
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0139969 OFBKPFEG_00003 2877 4 Oral 0.80 protein_coding synonymous_variant LOW 744C>T Val248Val
M0139970 OFBKPFEG_00003 3006 3 Oral 0.60 protein_coding synonymous_variant LOW 873A>C Leu291Leu
M0139971 OFBKPFEG_00003 3042 4 Oral 0.80 protein_coding synonymous_variant LOW 909C>T Gly303Gly
M0139972 OFBKPFEG_00003 3045 3 Oral 0.60 protein_coding synonymous_variant LOW 912A>G Val304Val
M0139973 OFBKPFEG_00003 3105 3 Oral 0.60 protein_coding synonymous_variant LOW 972G>A Glu324Glu
M0139974 OFBKPFEG_00003 3154 3 Oral 0.60 protein_coding missense_variant MODERATE 1021G>A Glu341Lys
M0139975 OFBKPFEG_00003 3156 3 Oral 0.60 protein_coding synonymous_variant LOW 1023A>G Glu341Glu
M0139976 OFBKPFEG_00003 3180 3 Oral 0.60 protein_coding synonymous_variant LOW 1047G>T Val349Val
M0139977 OFBKPFEG_00003 3181 3 Oral 0.60 protein_coding synonymous_variant LOW 1048T>C Leu350Leu
M0139978 OFBKPFEG_00003 3243 4 Oral 0.80 protein_coding synonymous_variant LOW 1110T>C Ser370Ser
M0139979 OFBKPFEG_00003 3267 3 Oral 0.60 protein_coding synonymous_variant LOW 1134T>C Gly378Gly
M0139980 OFBKPFEG_00004 3412 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -148T>C None
M0139981 OFBKPFEG_00004 4243 4 Oral 0.80 protein_coding synonymous_variant LOW 684A>T Ile228Ile
M0139982 OFBKPFEG_00004 4284 5 Oral 1.00 protein_coding missense_variant MODERATE 725A>G Asn242Ser
M0139983 OFBKPFEG_00004 4291 3 Oral 0.60 protein_coding synonymous_variant LOW 732T>C Tyr244Tyr
M0139984 OFBKPFEG_00004 4324 3 Oral 0.60 protein_coding synonymous_variant LOW 765T>A Val255Val
M0139985 OFBKPFEG_00004 4618 3 Oral 0.60 protein_coding synonymous_variant LOW 1059A>G Lys353Lys
M0139986 OFBKPFEG_00004 4627 4 Oral 0.80 protein_coding synonymous_variant LOW 1068A>G Leu356Leu
M0139987 OFBKPFEG_00004 4630 3 Oral 0.60 protein_coding synonymous_variant LOW 1071C>A Pro357Pro
M0139988 OFBKPFEG_00004 4972 3 Oral 0.60 protein_coding synonymous_variant LOW 1413T>C Ile471Ile
M0139989 OFBKPFEG_00004 5080 4 Oral 0.80 protein_coding synonymous_variant LOW 1521T>C Tyr507Tyr
M0139990 OFBKPFEG_00004 5152 3 Oral 0.60 protein_coding synonymous_variant LOW 1593T>A Ala531Ala
M0139991 OFBKPFEG_00004 5290 5 Oral 1.00 protein_coding synonymous_variant LOW 1731A>G Lys577Lys
M0139992 OFBKPFEG_00004 5659 3 Oral 0.60 protein_coding synonymous_variant LOW 2100C>T Tyr700Tyr
M0139993 OFBKPFEG_00008 5708 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -3444T>A None
M0139994 OFBKPFEG_00008 5710 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -3442A>G None
M0139995 OFBKPFEG_00008 5737 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -3415T>C None
M0139996 OFBKPFEG_00008 5788 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -3364A>C None
M0139997 OFBKPFEG_00005 6421 3 Oral 0.60 protein_coding missense_variant MODERATE 1100T>C Leu367Ser
M0139998 OFBKPFEG_00005 6651 3 Oral 0.60 protein_coding synonymous_variant LOW 870C>A Gly290Gly
M0139999 OFBKPFEG_00005 6723 3 Oral 0.60 protein_coding missense_variant MODERATE 798C>A Ser266Arg
M0140000 OFBKPFEG_00005 7086 3 Oral 0.60 protein_coding synonymous_variant LOW 435G>A Glu145Glu
M0140001 OFBKPFEG_00005 7118 3 Oral 0.60 protein_coding synonymous_variant LOW 403C>T Leu135Leu
M0140002 OFBKPFEG_00005 7189 3 Oral 0.60 protein_coding missense_variant MODERATE 332C>T Thr111Met
M0140003 OFBKPFEG_00003 2388 3 Oral 0.60 protein_coding synonymous_variant LOW 255C>A Ile85Ile
M0140004 OFBKPFEG_00003 2569 3 Oral 0.60 protein_coding missense_variant MODERATE 436A>T Ile146Phe
M0140005 OFBKPFEG_00003 2646 3 Oral 0.60 protein_coding synonymous_variant LOW 513C>T Phe171Phe
M0140006 OFBKPFEG_00003 2661 3 Oral 0.60 protein_coding synonymous_variant LOW 528T>C Leu176Leu
M0140007 OFBKPFEG_00003 2772 3 Oral 0.60 protein_coding synonymous_variant LOW 639T>C Asp213Asp
M0140008 OFBKPFEG_00003 2814 3 Oral 0.60 protein_coding missense_variant MODERATE 681T>G Asn227Lys
M0140009 OFBKPFEG_00003 2815 3 Oral 0.60 protein_coding missense_variant MODERATE 682G>A Val228Ile
M0140010 OFBKPFEG_00003 2816 3 Oral 0.60 protein_coding missense_variant MODERATE 683T>C Val228Ala
M0140011 OFBKPFEG_00003 2817 3 Oral 0.60 protein_coding synonymous_variant LOW 684C>T Val228Val
M0140012 OFBKPFEG_00003 3225 3 Oral 0.60 protein_coding synonymous_variant LOW 1092T>C Asp364Asp
M0140013 OFBKPFEG_00003 3354 3 Oral 0.60 protein_coding synonymous_variant LOW 1221C>T Thr407Thr
M0140014 OFBKPFEG_00004 3531 3 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -29A>T None
M0140015 OFBKPFEG_00004 5374 4 Oral 0.80 protein_coding synonymous_variant LOW 1815T>A Ala605Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term