Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C3391
  Reference Plasmid   MGYG000299185__MGYG000299185_82
  Reference Plasmid Size   7602
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0140016 HEHCLBNJ_00004 4277 3 Oral 0.50 protein_coding synonymous_variant LOW 441T>C Ala147Ala
M0140017 HEHCLBNJ_00004 4374 4 Oral 0.67 protein_coding missense_variant MODERATE 344T>C Val115Ala
M0140018 HEHCLBNJ_00004 4430 3 Oral 0.50 protein_coding synonymous_variant LOW 288T>C Ala96Ala
M0140019 HEHCLBNJ_00004 4516 3 Oral 0.50 protein_coding missense_variant MODERATE 202T>C Phe68Leu
M0140020 HEHCLBNJ_00004 4541 3 Oral 0.50 protein_coding synonymous_variant LOW 177T>C Asn59Asn
M0140021 HEHCLBNJ_00004 4625 3 Oral 0.50 protein_coding synonymous_variant LOW 93T>C Asn31Asn
M0140022 HEHCLBNJ_00005 4838 5 Oral 0.83 protein_coding missense_variant MODERATE 601G>A Ala201Thr
M0140023 HEHCLBNJ_00005 4887 5 Oral 0.83 protein_coding synonymous_variant LOW 552A>G Gly184Gly
M0140024 HEHCLBNJ_00005 4932 4 Oral 0.67 protein_coding synonymous_variant LOW 507C>A Gly169Gly
M0140025 HEHCLBNJ_00005 4938 4 Oral 0.67 protein_coding synonymous_variant LOW 501T>C Asn167Asn
M0140026 HEHCLBNJ_00005 5019 5 Oral 0.83 protein_coding synonymous_variant LOW 420A>G Gln140Gln
M0140027 HEHCLBNJ_00005 5055 4 Oral 0.67 protein_coding synonymous_variant LOW 384A>G Leu128Leu
M0140028 HEHCLBNJ_00005 5079 5 Oral 0.83 protein_coding synonymous_variant LOW 360G>A Glu120Glu
M0140029 HEHCLBNJ_00005 5088 5 Oral 0.83 protein_coding synonymous_variant LOW 351A>T Ile117Ile
M0140030 HEHCLBNJ_00005 5090 5 Oral 0.83 protein_coding missense_variant MODERATE 349A>C Ile117Leu
M0140031 HEHCLBNJ_00005 5091 3 Oral 0.50 protein_coding synonymous_variant LOW 348G>A Gln116Gln
M0140032 HEHCLBNJ_00005 5097 4 Oral 0.67 protein_coding synonymous_variant LOW 342A>G Leu114Leu
M0140033 HEHCLBNJ_00005 5397 4 Oral 0.67 protein_coding synonymous_variant LOW 42T>C Gly14Gly
M0140034 HEHCLBNJ_00006 5650 3 Oral 0.50 protein_coding synonymous_variant LOW 90A>T Thr30Thr
M0140035 HEHCLBNJ_00006 5786 3 Oral 0.50 protein_coding missense_variant MODERATE 226G>C Ala76Pro
M0140036 HEHCLBNJ_00006 5788 3 Oral 0.50 protein_coding synonymous_variant LOW 228T>A Ala76Ala
M0140037 HEHCLBNJ_00006 5794 3 Oral 0.50 protein_coding synonymous_variant LOW 234A>G Leu78Leu
M0140038 HEHCLBNJ_00006 5806 4 Oral 0.67 protein_coding synonymous_variant LOW 246A>G Val82Val
M0140039 HEHCLBNJ_00006 5807 3 Oral 0.50 protein_coding missense_variant MODERATE 247G>A Val83Met
M0140040 HEHCLBNJ_00006 5808 3 Oral 0.50 protein_coding missense_variant MODERATE 248T>C Val83Ala
M0140041 HEHCLBNJ_00006 5867 4 Oral 0.67 protein_coding missense_variant MODERATE 307A>C Ile103Leu
M0140042 HEHCLBNJ_00006 5932 4 Oral 0.67 protein_coding synonymous_variant LOW 372G>A Gly124Gly
M0140043 HEHCLBNJ_00006 5935 4 Oral 0.67 protein_coding synonymous_variant LOW 375A>G Lys125Lys
M0140044 HEHCLBNJ_00006 5960 4 Oral 0.67 protein_coding missense_variant MODERATE 400A>G Thr134Ala
M0140045 HEHCLBNJ_00006 6149 3 Oral 0.50 protein_coding missense_variant MODERATE 589C>G His197Asp
M0140046 HEHCLBNJ_00006 6166 4 Oral 0.67 protein_coding synonymous_variant LOW 606G>A Lys202Lys
M0140047 HEHCLBNJ_00006 6251 4 Oral 0.67 protein_coding missense_variant MODERATE 691A>G Asn231Asp
M0140048 HEHCLBNJ_00006 6373 3 Oral 0.50 protein_coding synonymous_variant LOW 813A>G Glu271Glu
M0140049 HEHCLBNJ_00006 6424 3 Oral 0.50 protein_coding synonymous_variant LOW 864T>A Ala288Ala
M0140050 HEHCLBNJ_00006 6445 3 Oral 0.50 protein_coding synonymous_variant LOW 885C>T Ile295Ile
M0140051 HEHCLBNJ_00006 6478 4 Oral 0.67 protein_coding synonymous_variant LOW 918C>T Asn306Asn
M0140052 HEHCLBNJ_00006 6484 4 Oral 0.67 protein_coding synonymous_variant LOW 924A>T Pro308Pro
M0140053 HEHCLBNJ_00006 6493 3 Oral 0.50 protein_coding synonymous_variant LOW 933C>T Asp311Asp
M0140054 HEHCLBNJ_00006 6506 3 Oral 0.50 protein_coding missense_variant MODERATE 946A>G Lys316Glu
M0140055 HEHCLBNJ_00007 6680 4 Oral 0.67 protein_coding synonymous_variant LOW 21A>T Val7Val
M0140056 HEHCLBNJ_00007 6739 4 Oral 0.67 protein_coding missense_variant MODERATE 80G>A Arg27Lys
M0140057 HEHCLBNJ_00007 6783 4 Oral 0.67 protein_coding synonymous_variant LOW 124T>C Leu42Leu
M0140058 HEHCLBNJ_00007 6833 3 Oral 0.50 protein_coding synonymous_variant LOW 174T>C Asp58Asp
M0140059 HEHCLBNJ_00007 7078 3 Oral 0.50 protein_coding missense_variant MODERATE 419T>C Val140Ala
M0140060 HEHCLBNJ_00007 7091 4 Oral 0.67 protein_coding synonymous_variant LOW 432T>A Thr144Thr
M0140061 HEHCLBNJ_00007 7112 4 Oral 0.67 protein_coding synonymous_variant LOW 453C>T Ile151Ile
M0140062 HEHCLBNJ_00005 4970 3 Oral 0.50 protein_coding synonymous_variant LOW 469T>C Leu157Leu
M0140063 HEHCLBNJ_00007 7214 3 Oral 0.50 protein_coding synonymous_variant LOW 555T>C Ser185Ser
M0140064 HEHCLBNJ_00007 7388 3 Oral 0.50 protein_coding synonymous_variant LOW 729A>G Ser243Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term