Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C269
  Reference Plasmid   NC_002698.1
  Reference Plasmid Size   221851
  Reference Plasmid GC Content   0.46
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0150650 GACCEJNO_00265 205535 3 Gut 0.38 protein_coding synonymous_variant LOW 1468T>C Leu490Leu
M0150651 GACCEJNO_00265 206147 3 Gut 0.38 protein_coding missense_variant MODERATE 2080G>A Gly694Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
GACCEJNO_00003 VFG012802 TTSS secreted effectors 100 2.9e-168 1 288 1.0 1 Effector delivery system type III secretion system effector OspB experiment
GACCEJNO_00013 VFG012793 TTSS secreted effectors 99.8 0 1 569 1.0 1 Effector delivery system type III secretion system effector OspD2 experiment
GACCEJNO_00014 VFG012812 TTSS secreted effectors 99.2 1.1e-136 1 239 1.0 1 Effector delivery system type III secretion system effector OspF, phosphothreonine lyase experiment
GACCEJNO_00025 VFG012788 TTSS secreted effectors 99.6 4.1e-125 1 225 1.0 1 Effector delivery system type III secretion system effector OspD1 experiment
GACCEJNO_00028 VFG012760 TTSS secreted effectors 100 1.5e-104 1 188 1.0 1 Effector delivery system type III secretion system effector IpgB2, guanine nucleotide exchange factor (GEF) experiment
GACCEJNO_00049 VFG013075 VirF 100 2.8e-141 1 261 1.0 0.9962 Regulation transcriptional activator VirF experiment
GACCEJNO_00050 VFG012825 TTSS secreted effectors 100 2.8e-45 1 88 1.0 1 Effector delivery system type III secretion system effector OspE2 experiment
GACCEJNO_00053 VFG012838 TTSS secreted effectors 99.6 0 1 563 1.0 1 Effector delivery system type III secretion system effector ipaH2.5, E3 ubiquitin ligase experiment
GACCEJNO_00063 VFG012773 TTSS secreted effectors 99.4 7.6e-278 1 484 1.0 1 Effector delivery system type III secretion system effector OspC2 experiment
GACCEJNO_00079 VFG002041 TTSS secreted effectors 100 0 1 565 1.0 1 Effector delivery system type III secretion system effector ipaH7.8, E3 ubiquitin ligase experiment
GACCEJNO_00080 VFG012841 TTSS secreted effectors 100 0 1 574 1.0 1 Effector delivery system type III secretion system effector ipaH4.5, E3 ubiquitin ligase experiment
GACCEJNO_00093 VFG012817 TTSS secreted effectors 100 0 1 565 1.0 1 Effector delivery system type III secretion system effector OspD3 experiment
GACCEJNO_00095 VFG012807 TTSS secreted effectors 99.8 3.9e-271 1 470 1.0 1 Effector delivery system type III secretion system effector OspC1 experiment
GACCEJNO_00119 VFG012778 TTSS secreted effectors 95.9 2.5e-268 1 484 1.0 1 Effector delivery system type III secretion system effector OspC3, ADP-riboxanase experiment
GACCEJNO_00128 VFG041905 TTSS secreted effectors 100 1.2e-115 1 201 1.0 0.7761 Effector delivery system type III secretion system effector IpaJ, cysteine protease experiment
GACCEJNO_00129 VFG012636 TTSS 100 6.3e-169 1 309 1.0 1 Effector delivery system transcriptional activator VirB experiment
GACCEJNO_00131 VFG000984 TTSS secreted effectors 99.8 0 1 633 1.0 1 Effector delivery system type III secretion system effector IpaA, vinculin binding protein experiment
GACCEJNO_00132 VFG000985 TTSS 99.7 7.7e-181 1 332 1.0 1 Effector delivery system type III secretion system hydrophilic translocator, needle tip protein IpaD experiment
GACCEJNO_00133 VFG000986 TTSS 99.2 1.5e-182 1 363 1.0 1 Effector delivery system type III secretion system hydrophilic translocator, pore protein IpaC experiment
GACCEJNO_00134 VFG000987 TTSS 99.8 9.4e-299 1 580 1.0 1 Effector delivery system type III secretion system hydrophilic translocator, pore protein IpaB experiment
GACCEJNO_00135 VFG000988 TTSS 100 8.3e-85 1 155 1.0 1 Effector delivery system type III secretion system chaperone for IpaB and IpaC experiment
GACCEJNO_00136 VFG000989 TTSS secreted effectors 99.5 2.8e-112 1 208 1.0 1 Effector delivery system type III secretion system effector IpgB1, guanine nucleotide exchange factor (GEF) experiment
GACCEJNO_00137 VFG000990 TTSS 100 7.9e-73 1 129 1.0 1 Effector delivery system type III secretion system chaperone for IcsB experiment
GACCEJNO_00138 VFG000991 TTSS secreted effectors 99.6 1.9e-284 1 494 1.0 1 Effector delivery system type III secretion system effector IcsB, fatty acyltransferase experiment
GACCEJNO_00139 VFG000992 TTSS secreted effectors 98.3 4.3e-306 1 538 1.0 1 Effector delivery system type III secretion system effector IpgD, phosphoinositide 4-phosphatase experiment
GACCEJNO_00140 VFG000993 TTSS 100 3e-66 1 120 1.0 1 Effector delivery system type III secretion system chaperone for IpgD experiment
GACCEJNO_00141 VFG000994 TTSS 99.3 1.3e-85 1 152 1.0 1 Effector delivery system type III secretion system protein IpgF experiment
GACCEJNO_00142 VFG000995 TTSS 100 4.5e-214 1 371 1.0 1 Effector delivery system type III secretion system outer MS ring protein MixG experiment
GACCEJNO_00143 VFG000996 TTSS 100 1.4e-41 1 83 1.0 1 Effector delivery system type III secretion system needle filament protein MxiH experiment
GACCEJNO_00144 VFG000997 TTSS 100 1.1e-45 1 97 1.0 1 Effector delivery system type III secretion system inner rod protein MxiI experiment
GACCEJNO_00145 VFG000998 TTSS 100 3.9e-123 1 228 1.0 0.9461 Effector delivery system type III secretion system inner MS ring protein MxiJ experiment
GACCEJNO_00146 VFG000999 TTSS 100 2.7e-100 1 175 1.0 1 Effector delivery system type III secretion system accessory cytosolic protein MxiK experiment
GACCEJNO_00147 VFG001000 TTSS 100 2.8e-126 1 226 1.0 0.9784 Effector delivery system type III secretion system stator MxiN experiment
GACCEJNO_00148 VFG001001 TTSS 99.3 3.8e-70 1 135 1.0 1 Effector delivery system type III secretion system protein MxiL experiment
GACCEJNO_00149 VFG001002 TTSS 100 1.5e-77 1 142 1.0 1 Effector delivery system type III secretion system pilotin MxiM experiment
GACCEJNO_00151 VFG001003 TTSS 100 3.5e-118 1 210 1.0 1 Effector delivery system type III secretion system regulatory protein MxiE experiment
GACCEJNO_00152 VFG001004 TTSS 99.8 0 1 566 1.0 1 Effector delivery system type III secretion system secretin MxiD experiment
GACCEJNO_00153 VFG001005 TTSS 99.7 5.5e-193 1 355 1.0 1 Effector delivery system type III secretion system gatekeeper MxiD experiment
GACCEJNO_00154 VFG001006 TTSS 100 0 1 686 1.0 1 Effector delivery system type III secretion system major export apparatus protein MxiA experiment
GACCEJNO_00155 VFG001007 TTSS 100 2.9e-70 1 133 1.0 1 Effector delivery system type III secretion system chaparone experiment
GACCEJNO_00156 VFG001008 TTSS 100 3.4e-245 1 430 1.0 1 Effector delivery system type III secretion system ATPase spa47 experiment
GACCEJNO_00157 VFG001009 TTSS 100 2.4e-57 1 112 1.0 1 Effector delivery system type III secretion system stalk protein Spa13 experiment
GACCEJNO_00158 VFG001010 TTSS 100 4.9e-163 1 292 1.0 1 Effector delivery system type III secretion system needle length regulator Spa32 experiment
GACCEJNO_00159 VFG001011 TTSS 99.2 5.5e-138 46 293 0.8464 1 Effector delivery system type III secretion system C ring protein Spa33 experiment
GACCEJNO_00160 VFG001012 TTSS 100 1.5e-113 1 216 1.0 1 Effector delivery system type III secretion system minor export apparatus protein Spa24 experiment
GACCEJNO_00161 VFG001013 TTSS 100 4.8e-42 1 86 1.0 1 Effector delivery system type III secretion system minor export apparatus protein Spa9 experiment
GACCEJNO_00162 VFG001014 TTSS 99.6 1.2e-133 1 256 1.0 1 Effector delivery system type III secretion system minor export apparatus protein Spa29 experiment
GACCEJNO_00163 VFG001015 TTSS 100 2.2e-183 1 342 1.0 1 Effector delivery system type III secretion system export apparatus switch protein Spa40 experiment
GACCEJNO_00190 VFG001016 TTSS secreted effectors 100 6.8e-232 1 400 1.0 1 Effector delivery system type III secretion system effector VirA, GTPase-activating protein (GAP) experiment
GACCEJNO_00191 VFG000667 IcsA (VirG) 99.9 0 1 1092 1.0 0.9909 Motility autotransporter, actin tail assembly protein IcsA/VirG experiment
GACCEJNO_00223 VFG042325 TTSS secreted effectors 99.5 2.6e-121 1 212 1.0 1 Effector delivery system type III secretion system effector OspI, glutamine deamidase experiment
GACCEJNO_00230 VFG002042 TTSS secreted effectors 99.6 1.50000000000017e-311 1 545 1.0 1 Effector delivery system type III secretion system effector ipaH9.8, E3 ubiquitin ligase experiment
GACCEJNO_00232 VFG002043 TTSS secreted effectors 100 1e-111 1 196 1.0 1 Effector delivery system type III secretion system effector OspG, protein kinase experiment
GACCEJNO_00276 VFG012833 TTSS secreted effectors 99.8 0 1 575 1.0 1 Effector delivery system type III secretion system effector ipaH1.4, E3 ubiquitin ligase experiment
GACCEJNO_00277 VFG012822 TTSS secreted effectors 100 6.2e-45 1 88 1.0 1 Effector delivery system type III secretion system effector OspE1 experiment
GACCEJNO_00284 VFG042215 TTSS secreted effectors 97.8 3.9e-105 1 186 0.9894 0.8087 Effector delivery system type III secretion system effector cysteine methyltransferase OspZ experiment
GACCEJNO_00286 VFG001017 IcsP (SopA) 100 1.4e-187 1 315 1.0 1 Exoenzyme outer membrane protease of the OmpP family, involved in cleavage of surface exposed IcsA experiment
GACCEJNO_00003 VFG012802 TTSS secreted effectors 100 2.2e-167 1 288 1.0 1 Effector delivery system type III secretion system effector OspB prediction
GACCEJNO_00013 VFG012794 TTSS secreted effectors 100 0 1 569 1.0 1 Effector delivery system type III secretion system effector OspD2 prediction
GACCEJNO_00014 VFG012813 TTSS secreted effectors 100 4.4e-137 1 239 1.0 1 Effector delivery system type III secretion system effector OspF, phosphothreonine lyase prediction
GACCEJNO_00025 VFG012789 TTSS secreted effectors 100 1e-124 1 225 1.0 1 Effector delivery system type III secretion system effector OspD1 prediction
GACCEJNO_00028 VFG012760 TTSS secreted effectors 100 1.1e-103 1 188 1.0 1 Effector delivery system type III secretion system effector IpgB2, guanine nucleotide exchange factor (GEF) prediction
GACCEJNO_00049 VFG013075 VirF 100 2.1e-140 1 261 1.0 0.9962 Regulation transcriptional activator VirF prediction
GACCEJNO_00050 VFG012825 TTSS secreted effectors 100 2.1e-44 1 88 1.0 1 Effector delivery system type III secretion system effector OspE2 prediction
GACCEJNO_00053 VFG012839 TTSS secreted effectors 100 0 1 563 1.0 1 Effector delivery system type III secretion system effector ipaH2.5, E3 ubiquitin ligase prediction
GACCEJNO_00063 VFG012774 TTSS secreted effectors 100 7.9e-279 1 484 1.0 1 Effector delivery system type III secretion system effector OspC2 prediction
GACCEJNO_00069 VFG012924 Serine protease 100 0 1 1364 1.0 1 Exoenzyme serine protease autotransporter toxin SepA prediction
GACCEJNO_00079 VFG002041 TTSS secreted effectors 100 0 1 565 1.0 1 Effector delivery system type III secretion system effector ipaH7.8, E3 ubiquitin ligase prediction
GACCEJNO_00080 VFG012841 TTSS secreted effectors 100 0 1 574 1.0 1 Effector delivery system type III secretion system effector ipaH4.5, E3 ubiquitin ligase prediction
GACCEJNO_00093 VFG012817 TTSS secreted effectors 100 0 1 565 1.0 1 Effector delivery system type III secretion system effector OspD3 prediction
GACCEJNO_00095 VFG012808 TTSS secreted effectors 100 5.9e-271 1 470 1.0 1 Effector delivery system type III secretion system effector OspC1 prediction
GACCEJNO_00119 VFG012779 TTSS secreted effectors 100 1.8e-278 1 484 1.0 1 Effector delivery system type III secretion system effector OspC3, ADP-riboxanase prediction
GACCEJNO_00128 VFG041905 TTSS secreted effectors 100 8.8e-115 1 201 1.0 0.7761 Effector delivery system type III secretion system effector IpaJ, cysteine protease prediction
GACCEJNO_00129 VFG012636 TTSS 100 4.7e-168 1 309 1.0 1 Effector delivery system transcriptional activator VirB prediction
GACCEJNO_00131 VFG012741 TTSS secreted effectors 100 0 1 633 1.0 1 Effector delivery system type III secretion system effector IpaA, vinculin binding protein prediction
GACCEJNO_00132 VFG012745 TTSS secreted effectors 100 1.5e-180 1 332 1.0 1 Effector delivery system type III secretion system hydrophilic translocator, needle tip protein IpaD prediction
GACCEJNO_00133 VFG012749 TTSS secreted effectors 100 1.6e-183 1 363 1.0 1 Effector delivery system type III secretion system hydrophilic translocator, pore protein IpaC prediction
GACCEJNO_00134 VFG012753 TTSS secreted effectors 100 1.8e-298 1 580 1.0 1 Effector delivery system type III secretion system hydrophilic translocator, pore protein IpaB prediction
GACCEJNO_00135 VFG000988 TTSS 100 6.2e-84 1 155 1.0 1 Effector delivery system type III secretion system chaperone for IpaB and IpaC prediction
GACCEJNO_00136 VFG012757 TTSS secreted effectors 100 9.4e-112 1 208 1.0 1 Effector delivery system type III secretion system effector IpgB1, guanine nucleotide exchange factor (GEF) prediction
GACCEJNO_00137 VFG000990 TTSS 100 5.9e-72 1 129 1.0 1 Effector delivery system type III secretion system chaperone for IcsB prediction
GACCEJNO_00138 VFG012770 TTSS secreted effectors 100 1.3e-284 1 494 1.0 1 Effector delivery system type III secretion system effector IcsB, fatty acyltransferase prediction
GACCEJNO_00139 VFG012766 TTSS secreted effectors 100 2.50000000000002e-310 1 538 1.0 1 Effector delivery system type III secretion system effector IpgD, phosphoinositide 4-phosphatase prediction
GACCEJNO_00140 VFG000993 TTSS 100 2.2e-65 1 120 1.0 1 Effector delivery system type III secretion system chaperone for IpgD prediction
GACCEJNO_00141 VFG012737 TTSS 100 1.9e-85 1 152 1.0 1 Effector delivery system type III secretion system protein IpgF prediction
GACCEJNO_00142 VFG000995 TTSS 100 3.4e-213 1 371 1.0 1 Effector delivery system type III secretion system outer MS ring protein MixG prediction
GACCEJNO_00143 VFG000996 TTSS 100 1e-40 1 83 1.0 1 Effector delivery system type III secretion system needle filament protein MxiH prediction
GACCEJNO_00144 VFG000997 TTSS 100 7.9e-45 1 97 1.0 1 Effector delivery system type III secretion system inner rod protein MxiI prediction
GACCEJNO_00145 VFG000998 TTSS 100 2.9e-122 1 228 1.0 0.9461 Effector delivery system type III secretion system inner MS ring protein MxiJ prediction
GACCEJNO_00146 VFG000999 TTSS 100 2e-99 1 175 1.0 1 Effector delivery system type III secretion system accessory cytosolic protein MxiK prediction
GACCEJNO_00147 VFG001000 TTSS 100 2.1e-125 1 226 1.0 0.9784 Effector delivery system type III secretion system stator MxiN prediction
GACCEJNO_00148 VFG012665 TTSS 100 4.4e-70 1 135 1.0 1 Effector delivery system type III secretion system protein MxiL prediction
GACCEJNO_00149 VFG001002 TTSS 100 1.1e-76 1 142 1.0 1 Effector delivery system type III secretion system pilotin MxiM prediction
GACCEJNO_00151 VFG001003 TTSS 100 2.6e-117 1 210 1.0 1 Effector delivery system type III secretion system regulatory protein MxiE prediction
GACCEJNO_00152 VFG012677 TTSS 100 0 1 566 1.0 1 Effector delivery system type III secretion system secretin MxiD prediction
GACCEJNO_00153 VFG012681 TTSS 100 1.9e-192 1 355 1.0 1 Effector delivery system type III secretion system gatekeeper MxiD prediction
GACCEJNO_00154 VFG001006 TTSS 100 0 1 686 1.0 1 Effector delivery system type III secretion system major export apparatus protein MxiA prediction
GACCEJNO_00155 VFG001007 TTSS 100 2.2e-69 1 133 1.0 1 Effector delivery system type III secretion system chaparone prediction
GACCEJNO_00156 VFG001008 TTSS 100 2.5e-244 1 430 1.0 1 Effector delivery system type III secretion system ATPase spa47 prediction
GACCEJNO_00157 VFG001009 TTSS 100 1.8e-56 1 112 1.0 1 Effector delivery system type III secretion system stalk protein Spa13 prediction
GACCEJNO_00158 VFG001010 TTSS 100 3.7e-162 1 292 1.0 1 Effector delivery system type III secretion system needle length regulator Spa32 prediction
GACCEJNO_00159 VFG012705 TTSS 100 3e-164 1 293 1.0 1 Effector delivery system type III secretion system C ring protein Spa33 prediction
GACCEJNO_00160 VFG001012 TTSS 100 1.2e-112 1 216 1.0 1 Effector delivery system type III secretion system minor export apparatus protein Spa24 prediction
GACCEJNO_00161 VFG001013 TTSS 100 3.6e-41 1 86 1.0 1 Effector delivery system type III secretion system minor export apparatus protein Spa9 prediction
GACCEJNO_00162 VFG012717 TTSS 100 7e-133 1 256 1.0 1 Effector delivery system type III secretion system minor export apparatus protein Spa29 prediction
GACCEJNO_00163 VFG001015 TTSS 100 1.7e-182 1 342 1.0 1 Effector delivery system type III secretion system export apparatus switch protein Spa40 prediction
GACCEJNO_00190 VFG001016 TTSS secreted effectors 100 5.1e-231 1 400 1.0 1 Effector delivery system type III secretion system effector VirA, GTPase-activating protein (GAP) prediction
GACCEJNO_00191 VFG013073 IcsA (VirG) 100 0 1 1092 1.0 0.9909 Motility autotransporter, actin tail assembly protein IcsA/VirG prediction
GACCEJNO_00223 VFG042325 TTSS secreted effectors 99.5 1.9e-120 1 212 1.0 1 Effector delivery system type III secretion system effector OspI, glutamine deamidase prediction
GACCEJNO_00230 VFG012852 TTSS secreted effectors 100 6.100000000002e-312 1 545 1.0 1 Effector delivery system type III secretion system effector ipaH9.8, E3 ubiquitin ligase prediction
GACCEJNO_00232 VFG002043 TTSS secreted effectors 100 7.5e-111 1 196 1.0 1 Effector delivery system type III secretion system effector OspG, protein kinase prediction
GACCEJNO_00243 VFG013079 VirK 100 5.5e-188 1 316 1.0 1 Others virulence factor VirK prediction
GACCEJNO_00244 VFG013084 MsbB2 100 2.7e-187 1 314 1.0 1 Others lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase prediction
GACCEJNO_00276 VFG012834 TTSS secreted effectors 100 0 1 575 1.0 1 Effector delivery system type III secretion system effector ipaH1.4, E3 ubiquitin ligase prediction
GACCEJNO_00277 VFG012822 TTSS secreted effectors 100 4.6e-44 1 88 1.0 1 Effector delivery system type III secretion system effector OspE1 prediction
GACCEJNO_00284 VFG042215 TTSS secreted effectors 97.8 2.9e-104 1 186 0.9894 0.8087 Effector delivery system type III secretion system effector cysteine methyltransferase OspZ prediction
GACCEJNO_00286 VFG001017 IcsP (SopA) 100 1e-186 1 315 1.0 1 Exoenzyme outer membrane protease of the OmpP family, involved in cleavage of surface exposed IcsA prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
GACCEJNO_00258 Mercury (Hg) 100 7.1e-78 1 144 1.0000 1.0000 experiment
GACCEJNO_00260 Mercury (Hg) 98.8 5.99999999978328e-314 1 561 1.0000 1.0000 experiment
GACCEJNO_00261 Mercury (Hg) 100 3.7e-48 1 92 1.0000 0.7603 experiment
GACCEJNO_00262 Mercury (Hg) 100 1.3e-41 1 78 1.0000 1.0000 experiment
GACCEJNO_00258 Mercury (Hg) 100 1.6e-75 1 144 1.0000 1.0000 prediction
GACCEJNO_00260 Mercury (Hg), Phenylmercury Acetate [class: Organo-mercury] 100 0 1 561 1.0000 1.0000 prediction
GACCEJNO_00261 Mercury (Hg) 100 8.6e-46 1 92 1.0000 0.7603 prediction
GACCEJNO_00262 Mercury (Hg) 100 3e-39 1 78 1.0000 1.0000 prediction
GACCEJNO_00263 Mercury (Hg) 100 5e-197 1 329 1.0000 0.8044 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
GACCEJNO_00028 PHI:4512 ipgB2 100 3.9e-104 1 188 1.0000 1.0000 rodents shigellosis type III effector effector (plant avirulence determinant)
GACCEJNO_00128 PHI:9253 ipaJ 100 3.1e-115 1 201 1.0000 0.7761 primates shigellosis effector protein effector (plant avirulence determinant)
GACCEJNO_00132 PHI:7721 IpaD 100 5.4e-181 1 332 1.0000 1.0000 primates shigellosis type three secretion system tip protein reduced virulence
GACCEJNO_00136 PHI:4511 ipgB1 99 3.7e-111 1 208 1.0000 1.0000 rodents shigellosis type III effector effector (plant avirulence determinant)
GACCEJNO_00138 PHI:11423 icsB 100 4.5e-285 1 494 1.0000 1.0000 primates shigellosis effector protein effector (plant avirulence determinant)
GACCEJNO_00143 PHI:10094 STM14_RS15405 (prgI) 70.8 8.2e-22 12 83 0.8675 0.9000 eudicots infection type III secretion system needle complex protein unaffected pathogenicity
GACCEJNO_00156 PHI:12182 spa47 100 8.9e-245 1 430 1.0000 1.0000 primates shigellosis protein-secreting ATPase unaffected pathogenicity
GACCEJNO_00159 PHI:9889 Spa33 100 1.1e-164 1 293 1.0000 1.0000 primates shigellosis surface presentation of antigens protein reduced virulence
GACCEJNO_00190 PHI:9252 virA 100 1.8e-231 1 400 1.0000 1.0000 primates shigellosis effector protein effector (plant avirulence determinant)
GACCEJNO_00191 PHI:4647 IcsA 99.9 0 1 1092 1.0000 0.9909 rodents shigellosis adhesin regulated by the type III secretion system reduced virulence
GACCEJNO_00242 PHI:10400 Sfgtr4 (ORF186) 99.4 6.9e-214 1 362 1.0000 1.0000 primates shigellosis putative lipopolysaccharides (LPS) glycosyltransferase (Gtr) reduced virulence
GACCEJNO_00286 PHI:6577 IcsP 100 3.6e-187 1 315 1.0000 1.0000 rodents shigellosis outer membrane protease reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
GACCEJNO_00141 CAC05810.1|GH23 100 4.93e-109 1 152 1 1
GACCEJNO_00242 QCC34366.1|GT4 100 8.93e-271 1 362 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
GACCEJNO_00134 1.C.36.3.1 98.6 4.8e-294 1 580 1.0000 1.0000 1 Channels/Pores 1.C Pore-Forming Toxins (Proteins and Peptides) 1.C.36 The Bacterial Type III-Target Cell Pore (IIITCP) Family
GACCEJNO_00155 3.A.6.1.2 100 1.7e-69 1 133 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.6 The Type III (Virulence-related) Secretory Pathway (IIISP) Family
GACCEJNO_00156 3.A.6.1.2 100 2e-244 1 430 1.0000 3.2331 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.6 The Type III (Virulence-related) Secretory Pathway (IIISP) Family
GACCEJNO_00157 3.A.6.1.2 100 1.4e-56 1 112 1.0000 0.8421 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.6 The Type III (Virulence-related) Secretory Pathway (IIISP) Family
GACCEJNO_00158 3.A.6.1.2 100 2.9e-162 1 292 1.0000 2.1955 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.6 The Type III (Virulence-related) Secretory Pathway (IIISP) Family
GACCEJNO_00159 3.A.6.1.2 100 2.4e-164 1 293 1.0000 2.2030 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.6 The Type III (Virulence-related) Secretory Pathway (IIISP) Family
GACCEJNO_00160 3.A.6.1.2 100 9.1e-113 1 216 1.0000 1.6241 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.6 The Type III (Virulence-related) Secretory Pathway (IIISP) Family
GACCEJNO_00162 3.A.6.1.2 100 5.5e-133 1 256 1.0000 1.9248 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.6 The Type III (Virulence-related) Secretory Pathway (IIISP) Family
GACCEJNO_00163 3.A.6.1.2 100 1.3e-182 1 342 1.0000 2.5714 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.6 The Type III (Virulence-related) Secretory Pathway (IIISP) Family
GACCEJNO_00191 1.B.12.1.2 99.9 0 1 1092 1.0000 0.9909 1 Channels/Pores 1.B β-Barrel Porins 1.B.12 The Autotransporter-1 (AT-1) Family
GACCEJNO_00262 1.A.72.5.1 76 3e-29 1 75 0.9615 0.9615 1 Channels/Pores 1.A α-Type Channels 1.A.72 The Mercuric Ion Pore (Mer) Superfamily