Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C270
  Reference Plasmid   NC_004252.1
  Reference Plasmid Size   10073
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0150652 KHPAFINP_00002 4298 4 Gut 0.40 protein_coding upstream_gene_variant MODIFIER -3139C>A None
M0150653 KHPAFINP_00007 5326 6 Gut 0.60 protein_coding synonymous_variant LOW 900C>T Val300Val
M0150654 KHPAFINP_00008 5509 6 Gut 0.60 protein_coding synonymous_variant LOW 651G>A Pro217Pro
M0150655 KHPAFINP_00008 5612 3 Gut 0.30 protein_coding missense_variant MODERATE 548G>A Arg183Lys
M0150656 KHPAFINP_00008 5647 6 Gut 0.60 protein_coding synonymous_variant LOW 513G>A Gly171Gly
M0150657 KHPAFINP_00008 5711 6 Gut 0.60 protein_coding missense_variant MODERATE 449A>G Asp150Gly
M0150658 KHPAFINP_00008 5851 5 Gut 0.50 protein_coding synonymous_variant LOW 309G>A Arg103Arg
M0150659 KHPAFINP_00008 5889 6 Gut 0.60 protein_coding missense_variant MODERATE 271G>A Ala91Thr
M0150660 KHPAFINP_00008 5892 5 Gut 0.50 protein_coding synonymous_variant LOW 268A>C Arg90Arg
M0150661 KHPAFINP_00008 5904 7 Gut 0.70 protein_coding missense_variant MODERATE 256G>A Gly86Arg
M0150662 KHPAFINP_00008 5937 4 Gut 0.40 protein_coding missense_variant MODERATE 223A>G Thr75Ala
M0150663 KHPAFINP_00008 5950 4 Gut 0.40 protein_coding synonymous_variant LOW 210A>G Pro70Pro
M0150664 KHPAFINP_00008 5956 3 Gut 0.30 protein_coding synonymous_variant LOW 204G>C Ala68Ala
M0150665 KHPAFINP_00008 5969 4 Gut 0.40 protein_coding missense_variant MODERATE 191A>G Lys64Arg
M0150666 KHPAFINP_00008 5983 4 Gut 0.40 protein_coding synonymous_variant LOW 177G>A Gly59Gly
M0150667 KHPAFINP_00008 6005 3 Gut 0.30 protein_coding missense_variant MODERATE 155G>A Arg52Gln
M0150668 KHPAFINP_00008 6007 3 Gut 0.30 protein_coding synonymous_variant LOW 153G>C Leu51Leu
M0150669 KHPAFINP_00008 6008 3 Gut 0.30 protein_coding missense_variant MODERATE 152T>G Leu51Arg
M0150670 KHPAFINP_00008 6030 3 Gut 0.30 protein_coding missense_variant MODERATE 130G>A Val44Ile
M0150671 KHPAFINP_00006 3662 3 Gut 0.30 protein_coding synonymous_variant LOW 90A>G Glu30Glu
M0150672 KHPAFINP_00006 3663 3 Gut 0.30 protein_coding missense_variant MODERATE 91G>T Ala31Ser
M0150673 KHPAFINP_00006 3666 3 Gut 0.30 protein_coding missense_variant MODERATE 94A>C Met32Leu
M0150674 KHPAFINP_00006 3715 3 Gut 0.30 protein_coding missense_variant MODERATE 143G>A Arg48Lys
M0150675 KHPAFINP_00010 7518 4 Gut 0.40 protein_coding synonymous_variant LOW 51T>C Ala17Ala
M0150676 KHPAFINP_00010 7581 3 Gut 0.30 protein_coding synonymous_variant LOW 114A>C Arg38Arg
M0150677 KHPAFINP_00010 7626 3 Gut 0.30 protein_coding synonymous_variant LOW 159C>G Ala53Ala
M0150678 KHPAFINP_00010 7638 3 Gut 0.30 protein_coding synonymous_variant LOW 171A>C Gly57Gly
M0150679 KHPAFINP_00010 7659 3 Gut 0.30 protein_coding synonymous_variant LOW 192A>G Glu64Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term