Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C291
  Reference Plasmid   NC_010659.1
  Reference Plasmid Size   5114
  Reference Plasmid GC Content   0.46
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0151351 PFEKCFLN_00001 335 6 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -17G>A None
M0151352 PFEKCFLN_00003 1396 6 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -703A>G None
M0151353 PFEKCFLN_00002 1492 6 Gut 0.60 protein_coding missense_variant MODERATE 436G>A Asp146Asn
M0151354 PFEKCFLN_00002 1576 5 Gut 0.50 protein_coding missense_variant MODERATE 352G>A Ala118Thr
M0151355 PFEKCFLN_00002 1791 6 Gut 0.60 protein_coding missense_variant MODERATE 137C>T Ser46Phe
M0151356 PFEKCFLN_00002 1796 6 Gut 0.60 protein_coding synonymous_variant LOW 132G>A Thr44Thr
M0151357 PFEKCFLN_00002 1981 7 Gut 0.70 protein_coding upstream_gene_variant MODIFIER -54G>T None
M0151358 PFEKCFLN_00002 2031 6 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -104C>A None
M0151359 PFEKCFLN_00002 2039 5 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -112G>A None
M0151360 PFEKCFLN_00002 2063 6 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -136T>G None
M0151361 PFEKCFLN_00002 2068 6 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -141G>T None
M0151362 PFEKCFLN_00003 2174 6 Gut 0.60 protein_coding missense_variant MODERATE 76T>A Ser26Thr
M0151363 PFEKCFLN_00003 2262 6 Gut 0.60 protein_coding missense_variant MODERATE 164A>C Glu55Ala
M0151364 PFEKCFLN_00001 129 5 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -223G>A None
M0151365 PFEKCFLN_00001 414 4 Gut 0.40 protein_coding missense_variant MODERATE 63T>G Asp21Glu
M0151366 PFEKCFLN_00003 2841 6 Gut 0.60 protein_coding missense_variant MODERATE 743C>G Ala248Gly
M0151367 PFEKCFLN_00003 2955 6 Gut 0.60 protein_coding missense_variant MODERATE 857T>C Met286Thr
M0151368 PFEKCFLN_00003 2973 6 Gut 0.60 protein_coding missense_variant MODERATE 875C>T Ala292Val
M0151369 PFEKCFLN_00003 3122 6 Gut 0.60 protein_coding missense_variant MODERATE 1024G>A Val342Ile
M0151370 PFEKCFLN_00003 3424 6 Gut 0.60 protein_coding synonymous_variant LOW 1326C>T Thr442Thr
M0151371 PFEKCFLN_00004 4007 5 Gut 0.50 protein_coding synonymous_variant LOW 939G>A Val313Val
M0151372 PFEKCFLN_00004 4028 6 Gut 0.60 protein_coding synonymous_variant LOW 918A>T Gly306Gly
M0151373 PFEKCFLN_00004 4068 6 Gut 0.60 protein_coding missense_variant MODERATE 878C>T Ala293Val
M0151374 PFEKCFLN_00004 4092 6 Gut 0.60 protein_coding missense_variant MODERATE 854G>T Arg285Ile
M0151375 PFEKCFLN_00004 4094 6 Gut 0.60 protein_coding synonymous_variant LOW 852C>T Cys284Cys
M0151376 PFEKCFLN_00004 4141 6 Gut 0.60 protein_coding missense_variant MODERATE 805G>A Asp269Asn
M0151377 PFEKCFLN_00004 4313 5 Gut 0.50 protein_coding synonymous_variant LOW 633A>G Ser211Ser
M0151378 PFEKCFLN_00004 4580 5 Gut 0.50 protein_coding synonymous_variant LOW 366G>A Leu122Leu
M0151379 PFEKCFLN_00004 4865 5 Gut 0.50 protein_coding synonymous_variant LOW 81G>A Lys27Lys
M0151380 PFEKCFLN_00004 4882 4 Gut 0.40 protein_coding missense_variant MODERATE 64T>C Ser22Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term