Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C318
  Reference Plasmid   NC_015163.1
  Reference Plasmid Size   97188
  Reference Plasmid GC Content   0.59
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0084641 ECILFHDI_00034 29706 5 Skin 0.28 protein_coding missense_variant MODERATE 277T>C Tyr93His
M0084642 ECILFHDI_00034 29750 5 Skin 0.28 protein_coding synonymous_variant LOW 321A>G Leu107Leu
M0084643 ECILFHDI_00035 30145 5 Skin 0.28 protein_coding synonymous_variant LOW 288G>C Pro96Pro
M0084644 ECILFHDI_00035 30157 5 Skin 0.28 protein_coding synonymous_variant LOW 300T>C Asn100Asn
M0084645 ECILFHDI_00035 30193 5 Skin 0.28 protein_coding synonymous_variant LOW 336C>T His112His
M0084646 ECILFHDI_00035 30230 5 Skin 0.28 protein_coding missense_variant MODERATE 373C>G Leu125Val
M0084647 ECILFHDI_00035 30415 5 Skin 0.28 protein_coding synonymous_variant LOW 558T>C Phe186Phe
M0084648 ECILFHDI_00035 30430 5 Skin 0.28 protein_coding synonymous_variant LOW 573C>A Ser191Ser
M0084649 ECILFHDI_00035 30526 5 Skin 0.28 protein_coding synonymous_variant LOW 669A>G Val223Val
M0084650 ECILFHDI_00035 30713 5 Skin 0.28 protein_coding missense_variant MODERATE 856A>G Thr286Ala
M0084651 ECILFHDI_00035 30716 5 Skin 0.28 protein_coding synonymous_variant LOW 859T>C Leu287Leu
M0084652 ECILFHDI_00035 30721 5 Skin 0.28 protein_coding synonymous_variant LOW 864T>G Pro288Pro
M0084653 ECILFHDI_00035 31514 4 Skin 0.22 protein_coding missense_variant MODERATE 1657T>C Tyr553His
M0084654 ECILFHDI_00030 26869 3 Skin 0.17 protein_coding synonymous_variant LOW 234G>T Gly78Gly
M0084655 ECILFHDI_00031 27367 4 Skin 0.22 protein_coding missense_variant MODERATE 317C>A Ala106Glu
M0084656 ECILFHDI_00030 27781 4 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -679T>C None
M0084657 ECILFHDI_00030 27837 4 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -735C>T None
M0084658 ECILFHDI_00032 27928 4 Skin 0.22 protein_coding missense_variant MODERATE 65T>C Val22Ala
M0084659 ECILFHDI_00032 27959 4 Skin 0.22 protein_coding synonymous_variant LOW 96T>G Ala32Ala
M0084660 ECILFHDI_00045 39570 4 Skin 0.22 protein_coding synonymous_variant LOW 555T>C Arg185Arg
M0084661 ECILFHDI_00046 40755 4 Skin 0.22 protein_coding synonymous_variant LOW 1071T>C Phe357Phe
M0084662 ECILFHDI_00046 40768 4 Skin 0.22 protein_coding missense_variant MODERATE 1084C>T Pro362Ser
M0084663 ECILFHDI_00040 41334 4 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -4351A>G None
M0084664 ECILFHDI_00046 40652 3 Skin 0.17 protein_coding missense_variant MODERATE 968A>G Asn323Ser
M0084665 ECILFHDI_00045 39147 3 Skin 0.17 protein_coding synonymous_variant LOW 132T>G Ala44Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term