Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C325
  Reference Plasmid   NC_017373.1
  Reference Plasmid Size   25916
  Reference Plasmid GC Content   0.34
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0153130 GIBIGNJN_00008 9597 4 Gut 0.67 protein_coding upstream_gene_variant MODIFIER -2144T>A None
M0153131 GIBIGNJN_00008 9625 4 Gut 0.67 protein_coding upstream_gene_variant MODIFIER -2172A>G None
M0153132 GIBIGNJN_00008 9641 4 Gut 0.67 protein_coding upstream_gene_variant MODIFIER -2188G>A None
M0153133 GIBIGNJN_00008 9698 3 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -2245T>C None
M0153134 GIBIGNJN_00008 9725 4 Gut 0.67 protein_coding upstream_gene_variant MODIFIER -2272C>T None
M0153135 GIBIGNJN_00008 9765 4 Gut 0.67 protein_coding upstream_gene_variant MODIFIER -2312A>G None
M0153136 GIBIGNJN_00011 10137 4 Gut 0.67 protein_coding missense_variant MODERATE 176C>T Thr59Ile
M0153137 GIBIGNJN_00011 10204 5 Gut 0.83 protein_coding synonymous_variant LOW 243A>G Ala81Ala
M0153138 GIBIGNJN_00011 10240 5 Gut 0.83 protein_coding synonymous_variant LOW 279C>T Ile93Ile
M0153139 GIBIGNJN_00011 10272 5 Gut 0.83 protein_coding missense_variant MODERATE 311G>A Arg104Lys
M0153140 GIBIGNJN_00011 10378 5 Gut 0.83 protein_coding synonymous_variant LOW 417C>T Asn139Asn
M0153141 GIBIGNJN_00011 10639 5 Gut 0.83 protein_coding synonymous_variant LOW 678G>A Gly226Gly
M0153142 GIBIGNJN_00011 10682 5 Gut 0.83 protein_coding missense_variant MODERATE 721C>T Pro241Ser
M0153143 GIBIGNJN_00011 10714 5 Gut 0.83 protein_coding synonymous_variant LOW 753G>A Leu251Leu
M0153144 GIBIGNJN_00011 10813 5 Gut 0.83 protein_coding synonymous_variant LOW 852A>G Arg284Arg
M0153145 GIBIGNJN_00012 11100 5 Gut 0.83 protein_coding synonymous_variant LOW 225A>G Thr75Thr
M0153146 GIBIGNJN_00012 11139 5 Gut 0.83 protein_coding synonymous_variant LOW 264A>G Ser88Ser
M0153147 GIBIGNJN_00012 11145 5 Gut 0.83 protein_coding synonymous_variant LOW 270T>C His90His
M0153148 GIBIGNJN_00012 11573 5 Gut 0.83 protein_coding missense_variant MODERATE 698G>A Ser233Asn
M0153149 GIBIGNJN_00012 11871 4 Gut 0.67 protein_coding synonymous_variant LOW 996A>C Leu332Leu
M0153150 GIBIGNJN_00012 11907 4 Gut 0.67 protein_coding synonymous_variant LOW 1032C>T Asp344Asp
M0153151 GIBIGNJN_00012 12054 4 Gut 0.67 protein_coding synonymous_variant LOW 1179A>G Gly393Gly
M0153152 GIBIGNJN_00012 12147 4 Gut 0.67 protein_coding synonymous_variant LOW 1272C>T Leu424Leu
M0153153 GIBIGNJN_00012 12186 4 Gut 0.67 protein_coding synonymous_variant LOW 1311C>T His437His
M0153154 GIBIGNJN_00013 12224 4 Gut 0.67 protein_coding synonymous_variant LOW 15C>T Tyr5Tyr
M0153155 GIBIGNJN_00013 12239 4 Gut 0.67 protein_coding synonymous_variant LOW 30C>T Ser10Ser
M0153156 GIBIGNJN_00013 12569 4 Gut 0.67 protein_coding synonymous_variant LOW 360C>T Asn120Asn
M0153157 GIBIGNJN_00013 12640 4 Gut 0.67 protein_coding missense_variant MODERATE 431A>G His144Arg
M0153158 GIBIGNJN_00013 12782 5 Gut 0.83 protein_coding synonymous_variant LOW 573T>C Ala191Ala
M0153159 GIBIGNJN_00013 12950 3 Gut 0.50 protein_coding synonymous_variant LOW 741C>T Ser247Ser
M0153160 GIBIGNJN_00014 13078 3 Gut 0.50 protein_coding missense_variant MODERATE 76G>A Glu26Lys
M0153161 GIBIGNJN_00014 13152 3 Gut 0.50 protein_coding synonymous_variant LOW 150A>G Leu50Leu
M0153162 GIBIGNJN_00014 13195 3 Gut 0.50 protein_coding missense_variant MODERATE 193A>G Lys65Glu
M0153163 GIBIGNJN_00014 13214 3 Gut 0.50 protein_coding missense_variant MODERATE 212C>T Ser71Phe
M0153164 GIBIGNJN_00014 13233 3 Gut 0.50 protein_coding synonymous_variant LOW 231T>C Cys77Cys
M0153165 GIBIGNJN_00014 13244 5 Gut 0.83 protein_coding missense_variant MODERATE 242A>G Asn81Ser
M0153166 GIBIGNJN_00014 13273 3 Gut 0.50 protein_coding missense_variant MODERATE 271A>G Thr91Ala
M0153167 GIBIGNJN_00014 13274 5 Gut 0.83 protein_coding missense_variant MODERATE 272C>T Thr91Ile
M0153168 GIBIGNJN_00014 13326 3 Gut 0.50 protein_coding missense_variant MODERATE 324T>G Phe108Leu
M0153169 GIBIGNJN_00014 13594 5 Gut 0.83 protein_coding synonymous_variant LOW 592C>T Leu198Leu
M0153170 GIBIGNJN_00014 13614 3 Gut 0.50 protein_coding synonymous_variant LOW 612T>C Ile204Ile
M0153171 GIBIGNJN_00014 13650 5 Gut 0.83 protein_coding synonymous_variant LOW 648A>G Leu216Leu
M0153172 GIBIGNJN_00014 13695 5 Gut 0.83 protein_coding synonymous_variant LOW 693C>T Phe231Phe
M0153173 GIBIGNJN_00014 13709 4 Gut 0.67 protein_coding missense_variant MODERATE 707C>T Thr236Ile
M0153174 GIBIGNJN_00014 13710 5 Gut 0.83 protein_coding synonymous_variant LOW 708A>C Thr236Thr
M0153175 GIBIGNJN_00014 13718 5 Gut 0.83 protein_coding missense_variant MODERATE 716A>G Lys239Arg
M0153176 GIBIGNJN_00014 13879 4 Gut 0.67 protein_coding missense_variant MODERATE 877A>G Lys293Glu
M0153177 GIBIGNJN_00014 13906 5 Gut 0.83 protein_coding missense_variant MODERATE 904A>G Thr302Ala
M0153178 GIBIGNJN_00014 13975 5 Gut 0.83 protein_coding missense_variant MODERATE 973A>C Lys325Gln
M0153179 GIBIGNJN_00014 14053 5 Gut 0.83 protein_coding missense_variant MODERATE 1051A>G Lys351Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term