Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C339
  Reference Plasmid   NC_019436.1
  Reference Plasmid Size   38673
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0153247 OHNCCDGN_00014 15982 6 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4906C>T None
M0153248 OHNCCDGN_00016 16168 6 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -3027A>C None
M0153249 OHNCCDGN_00016 16274 5 Gut 0.83 protein_coding upstream_gene_variant MODIFIER -3133G>T None
M0153250 OHNCCDGN_00016 16321 6 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -3180T>C None
M0153251 OHNCCDGN_00020 16380 5 Gut 0.83 protein_coding synonymous_variant LOW 48T>C Val16Val
M0153252 OHNCCDGN_00020 16656 6 Gut 1.00 protein_coding synonymous_variant LOW 324C>A Ala108Ala
M0153253 OHNCCDGN_00020 17589 6 Gut 1.00 protein_coding missense_variant MODERATE 1257T>A Asn419Lys
M0153254 OHNCCDGN_00020 17594 5 Gut 0.83 protein_coding missense_variant MODERATE 1262C>A Ala421Glu
M0153255 OHNCCDGN_00020 17895 5 Gut 0.83 protein_coding synonymous_variant LOW 1563G>T Gly521Gly
M0153256 OHNCCDGN_00021 18456 5 Gut 0.83 protein_coding synonymous_variant LOW 388C>T Leu130Leu
M0153257 OHNCCDGN_00021 18470 5 Gut 0.83 protein_coding missense_variant MODERATE 374C>T Ser125Leu
M0153258 OHNCCDGN_00021 18640 5 Gut 0.83 protein_coding synonymous_variant LOW 204G>A Leu68Leu
M0153259 OHNCCDGN_00021 18655 5 Gut 0.83 protein_coding synonymous_variant LOW 189A>G Val63Val
M0153260 OHNCCDGN_00017 18846 6 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4185T>G None
M0153261 OHNCCDGN_00022 19061 6 Gut 1.00 protein_coding missense_variant MODERATE 241A>G Lys81Glu
M0153262 OHNCCDGN_00022 19119 6 Gut 1.00 protein_coding synonymous_variant LOW 183C>T Ile61Ile
M0153263 OHNCCDGN_00017 19460 6 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4799T>C None
M0153264 OHNCCDGN_00017 19632 5 Gut 0.83 protein_coding upstream_gene_variant MODIFIER -4971T>C None
M0153265 OHNCCDGN_00018 19808 6 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4825A>G None
M0153266 OHNCCDGN_00023 19878 6 Gut 1.00 protein_coding missense_variant MODERATE 1342G>A Val448Ile
M0153267 OHNCCDGN_00023 19989 6 Gut 1.00 protein_coding missense_variant MODERATE 1231G>A Val411Ile
M0153268 OHNCCDGN_00023 20209 6 Gut 1.00 protein_coding synonymous_variant LOW 1011G>T Val337Val
M0153269 OHNCCDGN_00023 20540 6 Gut 1.00 protein_coding missense_variant MODERATE 680A>T Asp227Val
M0153270 OHNCCDGN_00023 20953 5 Gut 0.83 protein_coding synonymous_variant LOW 267G>A Ala89Ala
M0153271 OHNCCDGN_00023 20980 6 Gut 1.00 protein_coding synonymous_variant LOW 240A>G Leu80Leu
M0153272 OHNCCDGN_00023 21012 6 Gut 1.00 protein_coding missense_variant MODERATE 208T>G Ser70Ala
M0153273 OHNCCDGN_00023 21073 6 Gut 1.00 protein_coding synonymous_variant LOW 147T>C Gly49Gly
M0153274 OHNCCDGN_00023 21104 6 Gut 1.00 protein_coding missense_variant MODERATE 116T>G Leu39Arg
M0153275 OHNCCDGN_00023 21108 6 Gut 1.00 protein_coding missense_variant MODERATE 112A>C Thr38Pro
M0153276 OHNCCDGN_00023 21147 6 Gut 1.00 protein_coding missense_variant MODERATE 73T>G Ser25Ala
M0153277 OHNCCDGN_00021 21227 5 Gut 0.83 protein_coding upstream_gene_variant MODIFIER -2384A>G None
M0153278 OHNCCDGN_00024 21498 5 Gut 0.83 protein_coding synonymous_variant LOW 342C>T Leu114Leu
M0153279 OHNCCDGN_00024 21780 6 Gut 1.00 protein_coding synonymous_variant LOW 60C>T Asp20Asp
M0153280 OHNCCDGN_00026 22022 6 Gut 1.00 protein_coding missense_variant MODERATE 211G>A Ala71Thr
M0153281 OHNCCDGN_00026 22049 6 Gut 1.00 protein_coding missense_variant MODERATE 184C>G Arg62Gly
M0153282 OHNCCDGN_00026 22096 6 Gut 1.00 protein_coding missense_variant MODERATE 137A>T Asp46Val
M0153283 OHNCCDGN_00026 22097 6 Gut 1.00 protein_coding missense_variant MODERATE 136G>A Asp46Asn
M0153284 OHNCCDGN_00026 22106 6 Gut 1.00 protein_coding missense_variant MODERATE 127A>C Thr43Pro
M0153285 OHNCCDGN_00026 22128 6 Gut 1.00 protein_coding synonymous_variant LOW 105A>C Val35Val
M0153286 OHNCCDGN_00026 22129 6 Gut 1.00 protein_coding missense_variant MODERATE 104T>C Val35Ala
M0153287 OHNCCDGN_00026 22139 6 Gut 1.00 protein_coding missense_variant MODERATE 94C>A Leu32Ile
M0153288 OHNCCDGN_00026 22197 4 Gut 0.67 protein_coding synonymous_variant LOW 36T>C Thr12Thr
M0153289 OHNCCDGN_00026 22211 5 Gut 0.83 protein_coding missense_variant MODERATE 22C>T Pro8Ser
M0153290 OHNCCDGN_00026 22217 5 Gut 0.83 protein_coding missense_variant MODERATE 16C>T Pro6Ser
M0153291 OHNCCDGN_00021 22238 5 Gut 0.83 protein_coding upstream_gene_variant MODIFIER -3395T>A None
M0153292 OHNCCDGN_00027 22272 6 Gut 1.00 protein_coding missense_variant MODERATE 566T>G Ile189Ser
M0153293 OHNCCDGN_00027 22410 6 Gut 1.00 protein_coding missense_variant MODERATE 428G>C Gly143Ala
M0153294 OHNCCDGN_00027 22616 6 Gut 1.00 protein_coding synonymous_variant LOW 222A>G Gly74Gly
M0153295 OHNCCDGN_00027 22672 6 Gut 1.00 protein_coding missense_variant MODERATE 166T>A Cys56Ser
M0153296 OHNCCDGN_00021 22847 5 Gut 0.83 protein_coding upstream_gene_variant MODIFIER -4004A>T None
M0153297 OHNCCDGN_00021 22848 5 Gut 0.83 protein_coding upstream_gene_variant MODIFIER -4005A>T None
M0153298 OHNCCDGN_00021 22926 6 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4083C>T None
M0153299 OHNCCDGN_00021 22960 5 Gut 0.83 protein_coding upstream_gene_variant MODIFIER -4117G>A None
M0153300 OHNCCDGN_00021 22964 6 Gut 1.00 protein_coding upstream_gene_variant MODIFIER -4121A>T None
M0153301 OHNCCDGN_00021 22919 4 Gut 0.67 protein_coding upstream_gene_variant MODIFIER -4076G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
OHNCCDGN_00035 QRZ31157.1|CBM5|GH18 100 0 1 508 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term