Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C345
  Reference Plasmid   NC_022235.1
  Reference Plasmid Size   138306
  Reference Plasmid GC Content   0.63
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0085994 MGEBMAJP_00033 34493 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4059A>G None
M0085995 MGEBMAJP_00033 34520 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4086C>G None
M0085996 MGEBMAJP_00033 34545 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4111C>T None
M0085997 MGEBMAJP_00033 34554 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4120A>C None
M0085998 MGEBMAJP_00033 34555 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4121T>C None
M0085999 MGEBMAJP_00033 34597 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4163C>G None
M0086000 MGEBMAJP_00033 34599 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4165C>T None
M0086001 MGEBMAJP_00033 34604 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4170G>A None
M0086002 MGEBMAJP_00033 34659 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -4225T>C None
M0086003 MGEBMAJP_00038 34679 3 Skin 0.43 protein_coding synonymous_variant LOW 1050G>A Pro350Pro
M0086004 MGEBMAJP_00038 34688 3 Skin 0.43 protein_coding missense_variant MODERATE 1041A>C Glu347Asp
M0086005 MGEBMAJP_00038 34753 3 Skin 0.43 protein_coding missense_variant MODERATE 976C>G Pro326Ala
M0086006 MGEBMAJP_00038 34754 3 Skin 0.43 protein_coding missense_variant MODERATE 975T>A Asn325Lys
M0086007 MGEBMAJP_00038 34771 3 Skin 0.43 protein_coding missense_variant MODERATE 958C>A Pro320Thr
M0086008 MGEBMAJP_00038 34774 3 Skin 0.43 protein_coding missense_variant MODERATE 955A>G Thr319Ala
M0086009 MGEBMAJP_00038 34775 3 Skin 0.43 protein_coding missense_variant MODERATE 954C>G Asp318Glu
M0086010 MGEBMAJP_00038 34778 3 Skin 0.43 protein_coding synonymous_variant LOW 951C>T Asn317Asn
M0086011 MGEBMAJP_00038 34808 3 Skin 0.43 protein_coding synonymous_variant LOW 921C>G Leu307Leu
M0086012 MGEBMAJP_00038 34810 3 Skin 0.43 protein_coding missense_variant MODERATE 919C>T Leu307Phe
M0086013 MGEBMAJP_00038 34826 3 Skin 0.43 protein_coding synonymous_variant LOW 903G>C Arg301Arg
M0086014 MGEBMAJP_00038 34829 3 Skin 0.43 protein_coding synonymous_variant LOW 900C>G Leu300Leu
M0086015 MGEBMAJP_00038 34886 3 Skin 0.43 protein_coding synonymous_variant LOW 843T>G Pro281Pro
M0086016 MGEBMAJP_00038 34898 3 Skin 0.43 protein_coding synonymous_variant LOW 831C>G Leu277Leu
M0086017 MGEBMAJP_00038 34904 3 Skin 0.43 protein_coding synonymous_variant LOW 825T>C Arg275Arg
M0086018 MGEBMAJP_00038 34907 3 Skin 0.43 protein_coding synonymous_variant LOW 822A>G Ala274Ala
M0086019 MGEBMAJP_00038 34910 3 Skin 0.43 protein_coding synonymous_variant LOW 819C>T Asn273Asn
M0086020 MGEBMAJP_00038 34925 3 Skin 0.43 protein_coding synonymous_variant LOW 804A>G Ala268Ala
M0086021 MGEBMAJP_00038 34939 3 Skin 0.43 protein_coding synonymous_variant LOW 790C>A Arg264Arg
M0086022 MGEBMAJP_00038 34949 3 Skin 0.43 protein_coding synonymous_variant LOW 780A>C Pro260Pro
M0086023 MGEBMAJP_00038 34961 3 Skin 0.43 protein_coding synonymous_variant LOW 768C>T Ile256Ile
M0086024 MGEBMAJP_00038 34967 3 Skin 0.43 protein_coding synonymous_variant LOW 762A>G Pro254Pro
M0086025 MGEBMAJP_00038 34985 3 Skin 0.43 protein_coding synonymous_variant LOW 744A>G Ala248Ala
M0086026 MGEBMAJP_00038 35024 3 Skin 0.43 protein_coding synonymous_variant LOW 705A>C Ala235Ala
M0086027 MGEBMAJP_00038 35033 3 Skin 0.43 protein_coding synonymous_variant LOW 696C>A Ala232Ala
M0086028 MGEBMAJP_00038 35087 3 Skin 0.43 protein_coding synonymous_variant LOW 642C>G Leu214Leu
M0086029 MGEBMAJP_00038 35090 3 Skin 0.43 protein_coding synonymous_variant LOW 639C>G Ala213Ala
M0086030 MGEBMAJP_00038 35153 3 Skin 0.43 protein_coding synonymous_variant LOW 576A>G Glu192Glu
M0086031 MGEBMAJP_00038 35168 3 Skin 0.43 protein_coding synonymous_variant LOW 561G>A Lys187Lys
M0086032 MGEBMAJP_00038 35192 3 Skin 0.43 protein_coding synonymous_variant LOW 537A>G Ala179Ala
M0086033 MGEBMAJP_00038 35255 3 Skin 0.43 protein_coding synonymous_variant LOW 474G>A Arg158Arg
M0086034 MGEBMAJP_00038 35258 3 Skin 0.43 protein_coding synonymous_variant LOW 471G>T Gly157Gly
M0086035 MGEBMAJP_00038 35282 3 Skin 0.43 protein_coding synonymous_variant LOW 447A>G Ala149Ala
M0086036 MGEBMAJP_00038 35348 3 Skin 0.43 protein_coding synonymous_variant LOW 381C>G Leu127Leu
M0086037 MGEBMAJP_00038 35354 3 Skin 0.43 protein_coding synonymous_variant LOW 375G>A Glu125Glu
M0086038 MGEBMAJP_00038 35357 3 Skin 0.43 protein_coding synonymous_variant LOW 372T>G Leu124Leu
M0086039 MGEBMAJP_00038 35360 3 Skin 0.43 protein_coding synonymous_variant LOW 369C>T Asp123Asp
M0086040 MGEBMAJP_00038 35363 3 Skin 0.43 protein_coding synonymous_variant LOW 366T>C Thr122Thr
M0086041 MGEBMAJP_00038 35372 3 Skin 0.43 protein_coding synonymous_variant LOW 357C>T Val119Val
M0086042 MGEBMAJP_00038 35381 3 Skin 0.43 protein_coding synonymous_variant LOW 348T>G Pro116Pro
M0086043 MGEBMAJP_00038 35408 3 Skin 0.43 protein_coding missense_variant MODERATE 321G>C Leu107Phe
M0086044 MGEBMAJP_00038 35410 3 Skin 0.43 protein_coding synonymous_variant LOW 319T>C Leu107Leu
M0086045 MGEBMAJP_00038 35423 3 Skin 0.43 protein_coding synonymous_variant LOW 306C>G Ser102Ser
M0086046 MGEBMAJP_00038 35425 3 Skin 0.43 protein_coding missense_variant MODERATE 304T>G Ser102Ala
M0086047 MGEBMAJP_00038 35426 3 Skin 0.43 protein_coding synonymous_variant LOW 303T>C Asp101Asp
M0086048 MGEBMAJP_00038 35462 3 Skin 0.43 protein_coding synonymous_variant LOW 267C>T Phe89Phe
M0086049 MGEBMAJP_00038 35465 3 Skin 0.43 protein_coding synonymous_variant LOW 264T>C Ser88Ser
M0086050 MGEBMAJP_00038 35474 3 Skin 0.43 protein_coding synonymous_variant LOW 255G>C Val85Val
M0086051 MGEBMAJP_00038 35476 3 Skin 0.43 protein_coding missense_variant MODERATE 253G>A Val85Met
M0086052 MGEBMAJP_00038 35492 3 Skin 0.43 protein_coding synonymous_variant LOW 237T>C Ser79Ser
M0086053 MGEBMAJP_00038 35495 3 Skin 0.43 protein_coding synonymous_variant LOW 234G>A Ala78Ala
M0086054 MGEBMAJP_00038 35537 3 Skin 0.43 protein_coding synonymous_variant LOW 192G>C Thr64Thr
M0086055 MGEBMAJP_00038 35540 3 Skin 0.43 protein_coding synonymous_variant LOW 189A>G Ala63Ala
M0086056 MGEBMAJP_00038 35543 3 Skin 0.43 protein_coding synonymous_variant LOW 186G>C Leu62Leu
M0086057 MGEBMAJP_00038 35558 3 Skin 0.43 protein_coding synonymous_variant LOW 171A>G Ala57Ala
M0086058 MGEBMAJP_00038 35609 3 Skin 0.43 protein_coding synonymous_variant LOW 120G>A Glu40Glu
M0086059 MGEBMAJP_00034 35822 5 Skin 0.71 protein_coding upstream_gene_variant MODIFIER -3033T>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
MGEBMAJP_00129 Sodium Deoxycholate (SDC) [class: Acid] 100 8.5e-201 1 376 1.0000 1.0000 prediction
MGEBMAJP_00130 Sodium Deoxycholate (SDC) [class: Acid] 74.9 2.9e-215 6 515 0.9903 0.9884 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term