Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C354
  Reference Plasmid   NZ_AP017899.1
  Reference Plasmid Size   242612
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0086792 PMNMLFCN_00150 140913 5 Skin 0.23 protein_coding synonymous_variant LOW 690G>C Ser230Ser
M0086793 PMNMLFCN_00150 140922 5 Skin 0.23 protein_coding synonymous_variant LOW 699G>C Pro233Pro
M0086794 PMNMLFCN_00150 140964 5 Skin 0.23 protein_coding synonymous_variant LOW 741C>T Asp247Asp
M0086795 PMNMLFCN_00150 140973 5 Skin 0.23 protein_coding synonymous_variant LOW 750C>G Ala250Ala
M0086796 PMNMLFCN_00150 140985 5 Skin 0.23 protein_coding synonymous_variant LOW 762G>A Ala254Ala
M0086797 PMNMLFCN_00150 141018 5 Skin 0.23 protein_coding synonymous_variant LOW 795C>T Val265Val
M0086798 PMNMLFCN_00150 141024 5 Skin 0.23 protein_coding synonymous_variant LOW 801T>C Asp267Asp
M0086799 PMNMLFCN_00150 141042 5 Skin 0.23 protein_coding synonymous_variant LOW 819G>C Arg273Arg
M0086800 PMNMLFCN_00150 141057 4 Skin 0.18 protein_coding synonymous_variant LOW 834C>T Arg278Arg
M0086801 PMNMLFCN_00150 141072 5 Skin 0.23 protein_coding synonymous_variant LOW 849T>C Val283Val
M0086802 PMNMLFCN_00150 141084 5 Skin 0.23 protein_coding synonymous_variant LOW 861T>G Pro287Pro
M0086803 PMNMLFCN_00150 141087 5 Skin 0.23 protein_coding synonymous_variant LOW 864T>C Val288Val
M0086804 PMNMLFCN_00150 141123 5 Skin 0.23 protein_coding synonymous_variant LOW 900C>G Ser300Ser
M0086805 PMNMLFCN_00150 141174 4 Skin 0.18 protein_coding synonymous_variant LOW 951G>C Arg317Arg
M0086806 PMNMLFCN_00150 141195 4 Skin 0.18 protein_coding synonymous_variant LOW 972T>A Val324Val
M0086807 PMNMLFCN_00150 141208 4 Skin 0.18 protein_coding missense_variant MODERATE 985T>C Phe329Leu
M0086808 PMNMLFCN_00150 141212 5 Skin 0.23 protein_coding missense_variant MODERATE 989C>G Ala330Gly
M0086809 PMNMLFCN_00148 141222 4 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -2377G>A None
M0086810 PMNMLFCN_00148 141243 4 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -2398G>C None
M0086811 PMNMLFCN_00148 141273 4 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -2428C>T None
M0086812 PMNMLFCN_00148 142327 6 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -3482C>A None
M0086813 PMNMLFCN_00148 142533 6 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -3688T>C None
M0086814 PMNMLFCN_00152 142567 6 Skin 0.27 protein_coding synonymous_variant LOW 15G>A Thr5Thr
M0086815 PMNMLFCN_00152 142586 6 Skin 0.27 protein_coding missense_variant MODERATE 34G>A Val12Ile
M0086816 PMNMLFCN_00152 142600 6 Skin 0.27 protein_coding synonymous_variant LOW 48T>C Arg16Arg
M0086817 PMNMLFCN_00152 142609 6 Skin 0.27 protein_coding synonymous_variant LOW 57C>T Asn19Asn
M0086818 PMNMLFCN_00152 142660 6 Skin 0.27 protein_coding synonymous_variant LOW 108G>C Ser36Ser
M0086819 PMNMLFCN_00152 142717 6 Skin 0.27 protein_coding synonymous_variant LOW 165A>T Ile55Ile
M0086820 PMNMLFCN_00152 142723 6 Skin 0.27 protein_coding synonymous_variant LOW 171A>G Glu57Glu
M0086821 PMNMLFCN_00127 120519 3 Skin 0.14 protein_coding missense_variant MODERATE 79C>A Leu27Ile
M0086822 PMNMLFCN_00127 120551 3 Skin 0.14 protein_coding synonymous_variant LOW 111A>G Thr37Thr
M0086823 PMNMLFCN_00127 120563 3 Skin 0.14 protein_coding synonymous_variant LOW 123G>A Gly41Gly
M0086824 PMNMLFCN_00127 120612 3 Skin 0.14 protein_coding synonymous_variant LOW 172C>A Arg58Arg
M0086825 PMNMLFCN_00127 120664 3 Skin 0.14 protein_coding missense_variant MODERATE 224A>C Asn75Thr
M0086826 PMNMLFCN_00128 120797 3 Skin 0.14 protein_coding missense_variant MODERATE 76A>G Asn26Asp
M0086827 PMNMLFCN_00128 120885 3 Skin 0.14 protein_coding missense_variant MODERATE 164G>T Arg55Ile
M0086828 PMNMLFCN_00128 120973 3 Skin 0.14 protein_coding synonymous_variant LOW 252A>C Ser84Ser
M0086829 PMNMLFCN_00128 120976 3 Skin 0.14 protein_coding synonymous_variant LOW 255A>C Gly85Gly
M0086830 PMNMLFCN_00130 121081 3 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -571G>T None
M0086831 PMNMLFCN_00129 121117 3 Skin 0.14 protein_coding synonymous_variant LOW 468C>T Asp156Asp
M0086832 PMNMLFCN_00129 121122 3 Skin 0.14 protein_coding missense_variant MODERATE 463T>C Phe155Leu
M0086833 PMNMLFCN_00129 121156 4 Skin 0.18 protein_coding synonymous_variant LOW 429T>C Arg143Arg
M0086834 PMNMLFCN_00129 121294 4 Skin 0.18 protein_coding synonymous_variant LOW 291A>C Leu97Leu
M0086835 PMNMLFCN_00129 121363 4 Skin 0.18 protein_coding synonymous_variant LOW 222T>C Ser74Ser
M0086836 PMNMLFCN_00129 121386 4 Skin 0.18 protein_coding missense_variant MODERATE 199T>G Ser67Ala
M0086837 PMNMLFCN_00129 121411 3 Skin 0.14 protein_coding synonymous_variant LOW 174C>G Val58Val
M0086838 PMNMLFCN_00129 121471 3 Skin 0.14 protein_coding synonymous_variant LOW 114A>C Gly38Gly
M0086839 PMNMLFCN_00129 121545 4 Skin 0.18 protein_coding missense_variant MODERATE 40A>G Ile14Val
M0086840 PMNMLFCN_00150 140814 3 Skin 0.14 protein_coding synonymous_variant LOW 591A>G Ala197Ala
M0086841 PMNMLFCN_00129 121616 3 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -32G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term