Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C370
  Reference Plasmid   NZ_AP023206.1
  Reference Plasmid Size   404189
  Reference Plasmid GC Content   0.52
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0157113 DKMPNCBD_00328 363271 4 Gut 0.08 protein_coding missense_variant MODERATE 2224C>A Leu742Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
PEHEEDOF_00001 VFG000873 Type 1 fimbriae 90.1 1e-81 1 182 1.0 1 Adherence Type-1 fimbrial protein, A chain precursor experiment
PEHEEDOF_00002 VFG000874 Type 1 fimbriae 98.2 6.1e-94 1 165 1.0 0.9218 Adherence Fimbrin-like protein fimI precursor experiment
PEHEEDOF_00003 VFG000875 Type 1 fimbriae 98.8 7.4e-133 1 241 1.0 1 Adherence Chaperone protein fimC precursor experiment
PEHEEDOF_00004 VFG000876 Type 1 fimbriae 99.7 0 1 878 1.0 1 Adherence Outer membrane usher protein fimD precursor experiment
PEHEEDOF_00005 VFG000877 Type 1 fimbriae 99.4 1.4e-96 1 176 1.0 1 Adherence FimF protein precursor experiment
PEHEEDOF_00006 VFG000878 Type 1 fimbriae 98.2 8.1e-86 1 167 1.0 1 Adherence FimG protein precursor experiment
PEHEEDOF_00007 VFG000879 Type 1 fimbriae 99 4.7e-169 1 300 1.0 1 Adherence FimH protein precursor experiment
PEHEEDOF_00115 VFG034849 TTSS secreted effectors 92.2 3.2e-257 1 473 1.0 1 Effector delivery system Type III secretion system effector EspX1 experiment
PEHEEDOF_00187 VFG013412 LOS 77.3 1.1e-136 1 304 0.9967 0.9967 Immune modulation UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase experiment
PEHEEDOF_00310 VFG049898 T6SS 100 9.8e-89 1 160 1.0 1 Effector delivery system type VI secretion system protein, Hcp family experiment
PEHEEDOF_00311 VFG049899 T6SS 97.8 2.3e-252 1 450 1.0 1 Effector delivery system Type VI secretion system protein TssA experiment
PEHEEDOF_00312 VFG049902 T6SS 99.4 0 1 543 0.4625 0.9714 Effector delivery system Type VI secretion system protein TssM experiment
PEHEEDOF_00313 VFG049903 T6SS 99.4 1.3e-269 1 470 1.0 1 Effector delivery system Type VI secretion system protein TssA experiment
PEHEEDOF_00316 VFG049905 T6SS 99.6 2.5e-147 1 253 1.0 1 Effector delivery system Type VI secretion system protein TssL experiment
PEHEEDOF_00318 VFG049908 T6SS 99.4 9e-96 1 174 1.0 1 Effector delivery system Type VI secretion system protein TssJ experiment
PEHEEDOF_00319 VFG049909 T6SS 99.5 4e-246 1 426 1.0 1 Effector delivery system Type VI secretion system protein Fha experiment
PEHEEDOF_00320 VFG049910 T6SS 98.3 4.3e-209 1 360 1.0 1 Effector delivery system Type VI secretion system protein TssG experiment
PEHEEDOF_00321 VFG049911 T6SS 99.5 0 1 616 1.0 1 Effector delivery system Type VI secretion system protein TssF experiment
PEHEEDOF_00323 VFG038380 T6SS 73.1 3.2e-223 1 491 1.0 0.998 Effector delivery system Type VI secretion system contractile sheath large subunit TssC/VipB experiment
PEHEEDOF_00325 VFG049914 T6SS 99.4 1.9e-87 1 166 1.0 1 Effector delivery system Type VI secretion system protein TssB experiment
PEHEEDOF_00326 VFG049915 T6SS 99.4 9.1e-101 1 172 1.0 1 Effector delivery system Type VI secretion system protein, Hcp family experiment
PEHEEDOF_00327 VFG049916 T6SS 98.6 0 1 713 1.0 1 Effector delivery system type VI secretion system effector VgrG experiment
PEHEEDOF_00328 VFG049917 T6SS 91.5 0 1 1257 0.8397 0.8966 Effector delivery system Type VI secretion system protein, PAAR family experiment
PEHEEDOF_00335 VFG049917 T6SS 86.5 0 3 1258 0.9311 0.8959 Effector delivery system Type VI secretion system protein, PAAR family experiment
PEHEEDOF_00347 VFG013418 LOS 74.5 2e-80 1 192 1.0 0.9897 Immune modulation phosphoheptose isomerase experiment
DKMPNCBD_00001 VFG000873 Type 1 fimbriae 90.1 1e-81 1 182 1.0 1 Adherence Type-1 fimbrial protein, A chain precursor experiment
DKMPNCBD_00002 VFG000874 Type 1 fimbriae 98.2 6.1e-94 1 165 1.0 0.9218 Adherence Fimbrin-like protein fimI precursor experiment
DKMPNCBD_00003 VFG000875 Type 1 fimbriae 98.8 7.4e-133 1 241 1.0 1 Adherence Chaperone protein fimC precursor experiment
DKMPNCBD_00004 VFG000876 Type 1 fimbriae 99.7 0 1 878 1.0 1 Adherence Outer membrane usher protein fimD precursor experiment
DKMPNCBD_00005 VFG000877 Type 1 fimbriae 99.4 1.4e-96 1 176 1.0 1 Adherence FimF protein precursor experiment
DKMPNCBD_00006 VFG000878 Type 1 fimbriae 98.2 8.1e-86 1 167 1.0 1 Adherence FimG protein precursor experiment
DKMPNCBD_00007 VFG000879 Type 1 fimbriae 99 4.7e-169 1 300 1.0 1 Adherence FimH protein precursor experiment
DKMPNCBD_00115 VFG034849 TTSS secreted effectors 92.2 3.2e-257 1 473 1.0 1 Effector delivery system Type III secretion system effector EspX1 experiment
DKMPNCBD_00187 VFG013412 LOS 77.3 1.1e-136 1 304 0.9967 0.9967 Immune modulation UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase experiment
DKMPNCBD_00310 VFG049898 T6SS 100 9.8e-89 1 160 1.0 1 Effector delivery system type VI secretion system protein, Hcp family experiment
DKMPNCBD_00311 VFG049899 T6SS 97.8 2.3e-252 1 450 1.0 1 Effector delivery system Type VI secretion system protein TssA experiment
DKMPNCBD_00312 VFG049902 T6SS 99.4 0 1 543 0.4625 0.9714 Effector delivery system Type VI secretion system protein TssM experiment
DKMPNCBD_00313 VFG049903 T6SS 99.4 1.3e-269 1 470 1.0 1 Effector delivery system Type VI secretion system protein TssA experiment
DKMPNCBD_00316 VFG049905 T6SS 99.6 2.5e-147 1 253 1.0 1 Effector delivery system Type VI secretion system protein TssL experiment
DKMPNCBD_00318 VFG049908 T6SS 99.4 9e-96 1 174 1.0 1 Effector delivery system Type VI secretion system protein TssJ experiment
DKMPNCBD_00319 VFG049909 T6SS 99.5 4e-246 1 426 1.0 1 Effector delivery system Type VI secretion system protein Fha experiment
DKMPNCBD_00320 VFG049910 T6SS 98.3 4.3e-209 1 360 1.0 1 Effector delivery system Type VI secretion system protein TssG experiment
DKMPNCBD_00321 VFG049911 T6SS 99.5 0 1 616 1.0 1 Effector delivery system Type VI secretion system protein TssF experiment
DKMPNCBD_00323 VFG038380 T6SS 73.1 3.2e-223 1 491 1.0 0.998 Effector delivery system Type VI secretion system contractile sheath large subunit TssC/VipB experiment
DKMPNCBD_00325 VFG049914 T6SS 99.4 1.9e-87 1 166 1.0 1 Effector delivery system Type VI secretion system protein TssB experiment
DKMPNCBD_00326 VFG049915 T6SS 99.4 9.1e-101 1 172 1.0 1 Effector delivery system Type VI secretion system protein, Hcp family experiment
DKMPNCBD_00327 VFG049916 T6SS 98.6 0 1 713 1.0 1 Effector delivery system type VI secretion system effector VgrG experiment
DKMPNCBD_00328 VFG049917 T6SS 91.5 0 1 1257 0.8397 0.8966 Effector delivery system Type VI secretion system protein, PAAR family experiment
DKMPNCBD_00335 VFG049917 T6SS 86.5 0 3 1258 0.9311 0.8959 Effector delivery system Type VI secretion system protein, PAAR family experiment
DKMPNCBD_00347 VFG013418 LOS 74.5 2e-80 1 192 1.0 0.9897 Immune modulation phosphoheptose isomerase experiment
PEHEEDOF_00001 VFG033211 Type 1 fimbriae 100 1.8e-90 1 182 1.0 1 Adherence Type-1 fimbrial protein, A chain precursor prediction
PEHEEDOF_00002 VFG012284 Type 1 fimbriae 100 1.1e-94 1 165 1.0 0.9218 Adherence Fimbrin-like protein fimI precursor prediction
PEHEEDOF_00003 VFG033256 Type 1 fimbriae 99.6 5e-133 1 241 1.0 1 Adherence Chaperone protein fimC precursor prediction
PEHEEDOF_00004 VFG033285 Type 1 fimbriae 99.9 0 1 878 1.0 1 Adherence Outer membrane usher protein fimD precursor prediction
PEHEEDOF_00005 VFG033318 Type 1 fimbriae 100 4.7e-96 1 176 1.0 1 Adherence FimF protein precursor prediction
PEHEEDOF_00006 VFG012313 Type 1 fimbriae 99.4 9.3e-86 1 167 1.0 1 Adherence FimG protein precursor prediction
PEHEEDOF_00007 VFG033355 Type 1 fimbriae 100 1.4e-169 1 300 1.0 1 Adherence FimH protein precursor prediction
PEHEEDOF_00115 VFG034858 TTSS secreted effectors 97.9 2.4e-272 1 473 1.0 1 Effector delivery system Type III secretion system effector EspX1 prediction
PEHEEDOF_00187 VFG013414 LOS 77.3 6.2e-136 1 304 0.9967 0.9967 Immune modulation UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase prediction
PEHEEDOF_00195 VFG046022 Hemorrhagic E.coli pilus (HCP) 99.8 2.4e-225 1 400 1.0 1 Adherence protein transport protein HofC prediction
PEHEEDOF_00196 VFG045987 Hemorrhagic E.coli pilus (HCP) 100 2.1e-268 1 461 1.0 1 Adherence type II secretion system protein GspE prediction
PEHEEDOF_00197 VFG045950 Hemorrhagic E.coli pilus (HCP) 100 2.3e-80 1 146 1.0 1 Adherence prepilin peptidase-dependent pilin prediction
PEHEEDOF_00269 VFG013167 LOS 72.9 5e-110 1 262 1.0 1 Immune modulation UDP-N-acetylglucosamine acyltransferase prediction
PEHEEDOF_00310 VFG049898 T6SS 100 7.3e-88 1 160 1.0 1 Effector delivery system type VI secretion system protein, Hcp family prediction
PEHEEDOF_00311 VFG035469 ACE T6SS 99.1 2e-255 1 450 1.0 1 Effector delivery system type VI secretion system ImpA and VasL domain-containing protein prediction
PEHEEDOF_00312 VFG035495 ACE T6SS 99 0 31 1174 0.9744 1 Effector delivery system type VI secretion system membrane subunit TssM prediction
PEHEEDOF_00313 VFG035517 ACE T6SS 99.8 5e-270 1 470 1.0 1 Effector delivery system type VI secretion system protein TssA prediction
PEHEEDOF_00314 VFG035543 ACE T6SS 100 4.5e-137 1 247 1.0 1 Effector delivery system type VI secretion system-associated protein TagO prediction
PEHEEDOF_00315 VFG046086 ACE T6SS 97.2 0 1 919 1.0 0.9978 Effector delivery system type VI secretion system ATPase TssH prediction
PEHEEDOF_00316 VFG035603 ACE T6SS 100 4.9e-147 1 253 1.0 1 Effector delivery system type IVB secretion system protein IcmH/DotU prediction
PEHEEDOF_00317 VFG035629 ACE T6SS 99.8 6.4e-259 1 443 1.0 1 Effector delivery system type VI secretion system baseplate subunit TssK prediction
PEHEEDOF_00318 VFG035645 ACE T6SS 100 1.4e-95 1 174 1.0 1 Effector delivery system type VI secretion system lipoprotein TssJ prediction
PEHEEDOF_00319 VFG035671 ACE T6SS 100 3.5e-246 1 426 1.0 1 Effector delivery system type VI secretion system-associated FHA domain protein TagH prediction
PEHEEDOF_00320 VFG035703 ACE T6SS 100 1.1e-211 1 360 1.0 1 Effector delivery system type VI secretion system baseplate subunit TssG prediction
PEHEEDOF_00321 VFG035728 ACE T6SS 100 0 1 616 1.0 1 Effector delivery system type VI secretion system baseplate subunit TssF prediction
PEHEEDOF_00322 VFG035740 ACE T6SS 100 1.5e-73 1 137 1.0 1 Effector delivery system type VI secretion system baseplate subunit TssE prediction
PEHEEDOF_00323 VFG035769 ACE T6SS 100 1.7e-289 1 491 1.0 1 Effector delivery system type VI secretion system contractile sheath large subunit prediction
PEHEEDOF_00324 VFG041049 EHS 100 1.2e-37 1 74 1.0 1 Effector delivery system hypothetical protein prediction
PEHEEDOF_00325 VFG049914 T6SS 99.4 1.4e-86 1 166 1.0 1 Effector delivery system Type VI secretion system protein TssB prediction
PEHEEDOF_00326 VFG035808 EHS 100 1.1e-100 1 172 1.0 1 Effector delivery system Hcp family type VI secretion system effector prediction
PEHEEDOF_00327 VFG041051 EHS 98.9 0 1 713 1.0 1 Effector delivery system type VI secretion system tip protein VgrG prediction
PEHEEDOF_00328 VFG049917 T6SS 91.5 0 1 1257 0.8397 0.8966 Effector delivery system Type VI secretion system protein, PAAR family prediction
PEHEEDOF_00335 VFG049917 T6SS 86.5 0 3 1258 0.9311 0.8959 Effector delivery system Type VI secretion system protein, PAAR family prediction
PEHEEDOF_00347 VFG013422 LOS 75 8.8e-80 1 192 1.0 0.9897 Immune modulation phosphoheptose isomerase prediction
PEHEEDOF_00367 VFG043225 Lateral flagella 72.6 5.7e-183 1 445 1.0 0.9978 Others flagellar protein export ATPase FliI prediction
DKMPNCBD_00001 VFG033211 Type 1 fimbriae 100 1.8e-90 1 182 1.0 1 Adherence Type-1 fimbrial protein, A chain precursor prediction
DKMPNCBD_00002 VFG012284 Type 1 fimbriae 100 1.1e-94 1 165 1.0 0.9218 Adherence Fimbrin-like protein fimI precursor prediction
DKMPNCBD_00003 VFG033256 Type 1 fimbriae 99.6 5e-133 1 241 1.0 1 Adherence Chaperone protein fimC precursor prediction
DKMPNCBD_00004 VFG033285 Type 1 fimbriae 99.9 0 1 878 1.0 1 Adherence Outer membrane usher protein fimD precursor prediction
DKMPNCBD_00005 VFG033318 Type 1 fimbriae 100 4.7e-96 1 176 1.0 1 Adherence FimF protein precursor prediction
DKMPNCBD_00006 VFG012313 Type 1 fimbriae 99.4 9.3e-86 1 167 1.0 1 Adherence FimG protein precursor prediction
DKMPNCBD_00007 VFG033355 Type 1 fimbriae 100 1.4e-169 1 300 1.0 1 Adherence FimH protein precursor prediction
DKMPNCBD_00115 VFG034858 TTSS secreted effectors 97.9 2.4e-272 1 473 1.0 1 Effector delivery system Type III secretion system effector EspX1 prediction
DKMPNCBD_00187 VFG013414 LOS 77.3 6.2e-136 1 304 0.9967 0.9967 Immune modulation UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase prediction
DKMPNCBD_00195 VFG046022 Hemorrhagic E.coli pilus (HCP) 99.8 2.4e-225 1 400 1.0 1 Adherence protein transport protein HofC prediction
DKMPNCBD_00196 VFG045987 Hemorrhagic E.coli pilus (HCP) 100 2.1e-268 1 461 1.0 1 Adherence type II secretion system protein GspE prediction
DKMPNCBD_00197 VFG045950 Hemorrhagic E.coli pilus (HCP) 100 2.3e-80 1 146 1.0 1 Adherence prepilin peptidase-dependent pilin prediction
DKMPNCBD_00269 VFG013167 LOS 72.9 5e-110 1 262 1.0 1 Immune modulation UDP-N-acetylglucosamine acyltransferase prediction
DKMPNCBD_00310 VFG049898 T6SS 100 7.3e-88 1 160 1.0 1 Effector delivery system type VI secretion system protein, Hcp family prediction
DKMPNCBD_00311 VFG035469 ACE T6SS 99.1 2e-255 1 450 1.0 1 Effector delivery system type VI secretion system ImpA and VasL domain-containing protein prediction
DKMPNCBD_00312 VFG035495 ACE T6SS 99 0 31 1174 0.9744 1 Effector delivery system type VI secretion system membrane subunit TssM prediction
DKMPNCBD_00313 VFG035517 ACE T6SS 99.8 5e-270 1 470 1.0 1 Effector delivery system type VI secretion system protein TssA prediction
DKMPNCBD_00314 VFG035543 ACE T6SS 100 4.5e-137 1 247 1.0 1 Effector delivery system type VI secretion system-associated protein TagO prediction
DKMPNCBD_00315 VFG046086 ACE T6SS 97.2 0 1 919 1.0 0.9978 Effector delivery system type VI secretion system ATPase TssH prediction
DKMPNCBD_00316 VFG035603 ACE T6SS 100 4.9e-147 1 253 1.0 1 Effector delivery system type IVB secretion system protein IcmH/DotU prediction
DKMPNCBD_00317 VFG035629 ACE T6SS 99.8 6.4e-259 1 443 1.0 1 Effector delivery system type VI secretion system baseplate subunit TssK prediction
DKMPNCBD_00318 VFG035645 ACE T6SS 100 1.4e-95 1 174 1.0 1 Effector delivery system type VI secretion system lipoprotein TssJ prediction
DKMPNCBD_00319 VFG035671 ACE T6SS 100 3.5e-246 1 426 1.0 1 Effector delivery system type VI secretion system-associated FHA domain protein TagH prediction
DKMPNCBD_00320 VFG035703 ACE T6SS 100 1.1e-211 1 360 1.0 1 Effector delivery system type VI secretion system baseplate subunit TssG prediction
DKMPNCBD_00321 VFG035728 ACE T6SS 100 0 1 616 1.0 1 Effector delivery system type VI secretion system baseplate subunit TssF prediction
DKMPNCBD_00322 VFG035740 ACE T6SS 100 1.5e-73 1 137 1.0 1 Effector delivery system type VI secretion system baseplate subunit TssE prediction
DKMPNCBD_00323 VFG035769 ACE T6SS 100 1.7e-289 1 491 1.0 1 Effector delivery system type VI secretion system contractile sheath large subunit prediction
DKMPNCBD_00324 VFG041049 EHS 100 1.2e-37 1 74 1.0 1 Effector delivery system hypothetical protein prediction
DKMPNCBD_00325 VFG049914 T6SS 99.4 1.4e-86 1 166 1.0 1 Effector delivery system Type VI secretion system protein TssB prediction
DKMPNCBD_00326 VFG035808 EHS 100 1.1e-100 1 172 1.0 1 Effector delivery system Hcp family type VI secretion system effector prediction
DKMPNCBD_00327 VFG041051 EHS 98.9 0 1 713 1.0 1 Effector delivery system type VI secretion system tip protein VgrG prediction
DKMPNCBD_00328 VFG049917 T6SS 91.5 0 1 1257 0.8397 0.8966 Effector delivery system Type VI secretion system protein, PAAR family prediction
DKMPNCBD_00335 VFG049917 T6SS 86.5 0 3 1258 0.9311 0.8959 Effector delivery system Type VI secretion system protein, PAAR family prediction
DKMPNCBD_00347 VFG013422 LOS 75 8.8e-80 1 192 1.0 0.9897 Immune modulation phosphoheptose isomerase prediction
DKMPNCBD_00367 VFG043225 Lateral flagella 72.6 5.7e-183 1 445 1.0 0.9978 Others flagellar protein export ATPase FliI prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
PEHEEDOF_00027 Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Tetraphenylarsonium (TPA) [class: Quaternary Ammonium Compounds (QACs)] 97.8 1.2e-223 1 410 1.0000 1.0000 experiment
PEHEEDOF_00089 Silver (Ag), Mercury (Hg), Cadmium (Cd), Cyclohexane [class: Cycloalkane], Pentane [class: Alkane], n-hexane [class: Alkane], Diphenyl Ether [class: Phenyl] 100 6.9e-173 1 289 1.0000 1.0000 experiment
PEHEEDOF_00144 Cobalt (Co), Magnesium (Mg) 94.4 1.4e-66 1 125 1.0000 1.0000 experiment
PEHEEDOF_00148 n-hexane [class: Alkane] 100 0 1 784 1.0000 1.0000 experiment
PEHEEDOF_00212 Copper (Cu) 99.4 3.7e-310 1 516 1.0000 1.0000 experiment
PEHEEDOF_00281 Copper (Cu) 98.7 5.5e-136 1 236 1.0000 1.0000 experiment
DKMPNCBD_00027 Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Tetraphenylarsonium (TPA) [class: Quaternary Ammonium Compounds (QACs)] 97.8 1.2e-223 1 410 1.0000 1.0000 experiment
DKMPNCBD_00089 Silver (Ag), Mercury (Hg), Cadmium (Cd), Cyclohexane [class: Cycloalkane], Pentane [class: Alkane], n-hexane [class: Alkane], Diphenyl Ether [class: Phenyl] 100 6.9e-173 1 289 1.0000 1.0000 experiment
DKMPNCBD_00144 Cobalt (Co), Magnesium (Mg) 94.4 1.4e-66 1 125 1.0000 1.0000 experiment
DKMPNCBD_00148 n-hexane [class: Alkane] 100 0 1 784 1.0000 1.0000 experiment
DKMPNCBD_00212 Copper (Cu) 99.4 3.7e-310 1 516 1.0000 1.0000 experiment
DKMPNCBD_00281 Copper (Cu) 98.7 5.5e-136 1 236 1.0000 1.0000 experiment
PEHEEDOF_00027 Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Tetraphenylarsonium (TPA) [class: Quaternary Ammonium Compounds (QACs)] 100 1.4e-225 1 410 1.0000 1.0000 prediction
PEHEEDOF_00045 Palmitic acid [class: Free Fatty Acids] 100 3.6e-78 1 148 1.0000 1.0000 prediction
PEHEEDOF_00089 Silver (Ag), Mercury (Hg), Cadmium (Cd), Cyclohexane [class: Cycloalkane], Pentane [class: Alkane], n-hexane [class: Alkane], Diphenyl Ether [class: Phenyl] 100 1.6e-170 1 289 1.0000 1.0000 prediction
PEHEEDOF_00144 Cobalt (Co), Magnesium (Mg) 100 2.9e-68 1 125 1.0000 1.0000 prediction
PEHEEDOF_00148 n-hexane [class: Alkane] 100 0 1 784 1.0000 1.0000 prediction
PEHEEDOF_00212 Copper (Cu) 100 9.00000000000002e-310 1 516 1.0000 1.0000 prediction
PEHEEDOF_00281 Copper (Cu) 100 1.8e-135 1 236 1.0000 1.0000 prediction
DKMPNCBD_00027 Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Tetraphenylarsonium (TPA) [class: Quaternary Ammonium Compounds (QACs)] 100 1.4e-225 1 410 1.0000 1.0000 prediction
DKMPNCBD_00045 Palmitic acid [class: Free Fatty Acids] 100 3.6e-78 1 148 1.0000 1.0000 prediction
DKMPNCBD_00089 Silver (Ag), Mercury (Hg), Cadmium (Cd), Cyclohexane [class: Cycloalkane], Pentane [class: Alkane], n-hexane [class: Alkane], Diphenyl Ether [class: Phenyl] 100 1.6e-170 1 289 1.0000 1.0000 prediction
DKMPNCBD_00144 Cobalt (Co), Magnesium (Mg) 100 2.9e-68 1 125 1.0000 1.0000 prediction
DKMPNCBD_00148 n-hexane [class: Alkane] 100 0 1 784 1.0000 1.0000 prediction
DKMPNCBD_00212 Copper (Cu) 100 9.00000000000002e-310 1 516 1.0000 1.0000 prediction
DKMPNCBD_00281 Copper (Cu) 100 1.8e-135 1 236 1.0000 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
PEHEEDOF_00027 ARO:3001214 98 6.17e-283 1 409 0.9976 0.9976 fluoroquinolone antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux
PEHEEDOF_00148 ARO:3005059 82.3 0 1 784 1.0026 1.0051 carbapenem ATP-binding cassette (ABC) antibiotic efflux pump antibiotic efflux
PEHEEDOF_00168 ARO:3003843 99 2.49e-229 1 314 1.0000 1.0000 nucleoside antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux
PEHEEDOF_00175 ARO:3007421 93.7 0 1 588 1.0000 1.0000 cephalosporin Penicillin-binding protein mutations conferring resistance to beta-lactam antibiotics antibiotic target alteration
DKMPNCBD_00027 ARO:3001214 98 6.17e-283 1 409 0.9976 0.9976 fluoroquinolone antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux
DKMPNCBD_00148 ARO:3005059 82.3 0 1 784 1.0026 1.0051 carbapenem ATP-binding cassette (ABC) antibiotic efflux pump antibiotic efflux
DKMPNCBD_00168 ARO:3003843 99 2.49e-229 1 314 1.0000 1.0000 nucleoside antibiotic major facilitator superfamily (MFS) antibiotic efflux pump antibiotic efflux
DKMPNCBD_00175 ARO:3007421 93.7 0 1 588 1.0000 1.0000 cephalosporin Penicillin-binding protein mutations conferring resistance to beta-lactam antibiotics antibiotic target alteration






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
PEHEEDOF_00001 PHI:9888 fimA 95.1 2.1e-86 1 182 1.0000 1.0000 primates infection major type 1 subunit fimbrin (pilin) unaffected pathogenicity
PEHEEDOF_00002 PHI:10208 fimI 74.8 3.1e-73 3 165 0.9879 0.9157 rodents pneumonia pilin (type 1 fimbria component protein) unaffected pathogenicity
PEHEEDOF_00006 PHI:123639 fimG 98.2 6.2e-85 1 167 1.0000 1.0000 rodents neonatal meningitis fimbrial protein reduced virulence
PEHEEDOF_00007 PHI:2690 FimH 99.7 1.5e-169 1 300 1.0000 1.0000 rodents Crohn's disease adhesion reduced virulence
PEHEEDOF_00034 PHI:7575 yjiY 96.4 0 1 716 1.0000 1.0000 rodents salmonellosis peptide-utilizing carbon starvation protein reduced virulence
PEHEEDOF_00046 PHI:6981 tsr 87.2 6.1e-254 1 554 1.0000 1.0000 primates salmonellosis methyl-accepting chemotaxis protein reduced virulence
PEHEEDOF_00091 PHI:11268 creB 84.3 6.9e-111 1 229 1.0000 1.0000 rodents infection response regulator in two-component regulatory system reduced virulence
PEHEEDOF_00094 PHI:6532 arcA 100 9.9e-137 1 238 1.0000 1.0000 birds meningitis aerobic respiration control protein reduced virulence
PEHEEDOF_00101 PHI:11408 yaaA 82.9 4.9e-121 1 257 0.9961 0.9509 rodents pneumonia alanine/glycine transport protein reduced virulence
PEHEEDOF_00105 PHI:9230 satP 100 1.6e-102 1 188 1.0000 1.0000 birds avian colisepticemia succinate-acetate/proton symporter unaffected pathogenicity
PEHEEDOF_00111 PHI:3266 nhaA 99.5 1.7e-210 1 388 1.0000 1.0000 rodents infection antiporter gene reduced virulence
PEHEEDOF_00112 PHI:3267 nhaR 99.7 9.8e-174 1 299 1.0000 0.9934 rodents infection transcriptional activator protein reduced virulence
PEHEEDOF_00124 PHI:8577 carA (Dda3937_01390) 87.4 3.3e-198 1 380 0.9948 0.9974 eudicots soft rot carbamoyl-phosphate synthase small subunit reduced virulence
PEHEEDOF_00145 PHI:10573 rsmA 79.8 1.4e-123 1 272 0.9963 1.0000 monocots soft rot ribosomal RNA small subunit methyltransferase A unaffected pathogenicity
PEHEEDOF_00148 PHI:10312 LptD 100 0 1 784 1.0000 1.0000 moths urinary tract infection LPS-assembly protein increased virulence (hypervirulence)
PEHEEDOF_00160 PHI:123649 yabL 99.1 4.8e-190 1 327 1.0000 1.0000 rodents neonatal meningitis regulatory protein unaffected pathogenicity
PEHEEDOF_00164 PHI:8965 leuD 88.1 1.4e-104 1 201 1.0000 1.0000 rodents pneumonia 3-isopropylmalate dehydratase small subunit reduced virulence
PEHEEDOF_00165 PHI:8964 leuC 97.4 3.4e-266 1 466 1.0000 1.0000 rodents pneumonia 3-isopropylmalate dehydratase large subunit reduced virulence
PEHEEDOF_00166 PHI:8862 LeuB 94.2 5.3e-198 1 363 1.0000 1.0000 rodents infection 3-isopropylmalate dehydrogenase reduced virulence
PEHEEDOF_00167 PHI:8962 leuA 92.7 5.5e-281 1 523 1.0000 1.0000 rodents pneumonia 2-isopropylmalate synthase reduced virulence
PEHEEDOF_00171 PHI:2672 fruR 98.8 2.2e-190 1 334 1.0000 1.0000 rodents food poisoning regulators of systemic infection reduced virulence
PEHEEDOF_00202 PHI:3135 pdhR 86.2 5.5e-117 1 253 0.9961 0.9961 rodents gut-associated disease; diarrhea; enteritis; colitis part of the pyruvate-tricarboxylic acid cycle node reduced virulence
PEHEEDOF_00209 PHI:9152 speD 100 2.4e-155 1 264 1.0000 1.0000 birds colibacillosis S-adenosylmethionine decarboxylase proenzyme unaffected pathogenicity
PEHEEDOF_00210 PHI:9153 speE 99.7 1.8e-172 1 288 1.0000 1.0000 birds colibacillosis polyamine aminopropyltransferase unaffected pathogenicity
PEHEEDOF_00212 PHI:10985 cueO 99.4 6.2e-309 1 516 1.0000 1.0000 rodents infection blue copper oxidase reduced virulence
PEHEEDOF_00234 PHI:6508 DksA 98.7 5.8e-82 1 151 1.0000 1.0000 rodents salmonellosis response regulator reduced virulence
PEHEEDOF_00241 PHI:10989 fhuD 99.3 6.9e-172 1 296 1.0000 1.0000 rodents infection iron(III) hydroxamate ABC transporter periplasmic binding protein unaffected pathogenicity
PEHEEDOF_00250 PHI:8690 degP (ROD_01651) 94.3 2.2e-244 1 474 1.0000 1.0000 rodents colitis periplasmic serine endoprotease DegP-like loss of pathogenicity
PEHEEDOF_00255 PHI:9334 map 89.8 1.9e-141 1 264 1.0000 1.0000 rodents colitis effector protein effector (plant avirulence determinant)
PEHEEDOF_00281 PHI:8514 nlpE 79.3 3.9e-109 2 233 0.9831 0.9957 rodents colitis outer-membrane lipoprotein unaffected pathogenicity
PEHEEDOF_00312 PHI:12052 icmF 78.2 0 1 1174 1.0000 1.0000 eukaryotes colibacillosis type VI secretion system protein unaffected pathogenicity
PEHEEDOF_00315 PHI:4559 T6SS2 90.2 0 1 919 1.0000 1.0000 birds meningitis type VI secretion systems (T6SSs) effectors effector (plant avirulence determinant)
PEHEEDOF_00316 PHI:12050 impK 98 8.1e-145 1 253 1.0000 1.0000 eukaryotes colibacillosis type VI secretion system protein unaffected pathogenicity
PEHEEDOF_00323 PHI:12051 evpB 99.8 1.8e-289 1 491 1.0000 1.0000 eukaryotes colibacillosis type VI secretion system protein unaffected pathogenicity
PEHEEDOF_00326 PHI:8554 hcp2 100 3.7e-101 1 172 1.0000 1.0000 birds avian colibacillosis hemolysin co-regulation protein reduced virulence
PEHEEDOF_00327 PHI:4560 VgrG 99.2 0 1 713 1.0000 1.0000 birds meningitis type VI secretion systems (T6SSs) effectors effector (plant avirulence determinant)
PEHEEDOF_00345 PHI:2647 ivy 99.4 2.6e-85 1 157 1.0000 1.0000 birds colibacillosis; cellulitis; swollen head syndrome lysozyme inhibitor unaffected pathogenicity
DKMPNCBD_00001 PHI:9888 fimA 95.1 2.1e-86 1 182 1.0000 1.0000 primates infection major type 1 subunit fimbrin (pilin) unaffected pathogenicity
DKMPNCBD_00002 PHI:10208 fimI 74.8 3.1e-73 3 165 0.9879 0.9157 rodents pneumonia pilin (type 1 fimbria component protein) unaffected pathogenicity
DKMPNCBD_00006 PHI:123639 fimG 98.2 6.2e-85 1 167 1.0000 1.0000 rodents neonatal meningitis fimbrial protein reduced virulence
DKMPNCBD_00007 PHI:2690 FimH 99.7 1.5e-169 1 300 1.0000 1.0000 rodents Crohn's disease adhesion reduced virulence
DKMPNCBD_00034 PHI:7575 yjiY 96.4 0 1 716 1.0000 1.0000 rodents salmonellosis peptide-utilizing carbon starvation protein reduced virulence
DKMPNCBD_00046 PHI:6981 tsr 87.2 6.1e-254 1 554 1.0000 1.0000 primates salmonellosis methyl-accepting chemotaxis protein reduced virulence
DKMPNCBD_00091 PHI:11268 creB 84.3 6.9e-111 1 229 1.0000 1.0000 rodents infection response regulator in two-component regulatory system reduced virulence
DKMPNCBD_00094 PHI:6532 arcA 100 9.9e-137 1 238 1.0000 1.0000 birds meningitis aerobic respiration control protein reduced virulence
DKMPNCBD_00101 PHI:11408 yaaA 82.9 4.9e-121 1 257 0.9961 0.9509 rodents pneumonia alanine/glycine transport protein reduced virulence
DKMPNCBD_00105 PHI:9230 satP 100 1.6e-102 1 188 1.0000 1.0000 birds avian colisepticemia succinate-acetate/proton symporter unaffected pathogenicity
DKMPNCBD_00111 PHI:3266 nhaA 99.5 1.7e-210 1 388 1.0000 1.0000 rodents infection antiporter gene reduced virulence
DKMPNCBD_00112 PHI:3267 nhaR 99.7 9.8e-174 1 299 1.0000 0.9934 rodents infection transcriptional activator protein reduced virulence
DKMPNCBD_00124 PHI:8577 carA (Dda3937_01390) 87.4 3.3e-198 1 380 0.9948 0.9974 eudicots soft rot carbamoyl-phosphate synthase small subunit reduced virulence
DKMPNCBD_00145 PHI:10573 rsmA 79.8 1.4e-123 1 272 0.9963 1.0000 monocots soft rot ribosomal RNA small subunit methyltransferase A unaffected pathogenicity
DKMPNCBD_00148 PHI:10312 LptD 100 0 1 784 1.0000 1.0000 moths urinary tract infection LPS-assembly protein increased virulence (hypervirulence)
DKMPNCBD_00160 PHI:123649 yabL 99.1 4.8e-190 1 327 1.0000 1.0000 rodents neonatal meningitis regulatory protein unaffected pathogenicity
DKMPNCBD_00164 PHI:8965 leuD 88.1 1.4e-104 1 201 1.0000 1.0000 rodents pneumonia 3-isopropylmalate dehydratase small subunit reduced virulence
DKMPNCBD_00165 PHI:8964 leuC 97.4 3.4e-266 1 466 1.0000 1.0000 rodents pneumonia 3-isopropylmalate dehydratase large subunit reduced virulence
DKMPNCBD_00166 PHI:8862 LeuB 94.2 5.3e-198 1 363 1.0000 1.0000 rodents infection 3-isopropylmalate dehydrogenase reduced virulence
DKMPNCBD_00167 PHI:8962 leuA 92.7 5.5e-281 1 523 1.0000 1.0000 rodents pneumonia 2-isopropylmalate synthase reduced virulence
DKMPNCBD_00171 PHI:2672 fruR 98.8 2.2e-190 1 334 1.0000 1.0000 rodents food poisoning regulators of systemic infection reduced virulence
DKMPNCBD_00202 PHI:3135 pdhR 86.2 5.5e-117 1 253 0.9961 0.9961 rodents gut-associated disease; diarrhea; enteritis; colitis part of the pyruvate-tricarboxylic acid cycle node reduced virulence
DKMPNCBD_00209 PHI:9152 speD 100 2.4e-155 1 264 1.0000 1.0000 birds colibacillosis S-adenosylmethionine decarboxylase proenzyme unaffected pathogenicity
DKMPNCBD_00210 PHI:9153 speE 99.7 1.8e-172 1 288 1.0000 1.0000 birds colibacillosis polyamine aminopropyltransferase unaffected pathogenicity
DKMPNCBD_00212 PHI:10985 cueO 99.4 6.2e-309 1 516 1.0000 1.0000 rodents infection blue copper oxidase reduced virulence
DKMPNCBD_00234 PHI:6508 DksA 98.7 5.8e-82 1 151 1.0000 1.0000 rodents salmonellosis response regulator reduced virulence
DKMPNCBD_00241 PHI:10989 fhuD 99.3 6.9e-172 1 296 1.0000 1.0000 rodents infection iron(III) hydroxamate ABC transporter periplasmic binding protein unaffected pathogenicity
DKMPNCBD_00250 PHI:8690 degP (ROD_01651) 94.3 2.2e-244 1 474 1.0000 1.0000 rodents colitis periplasmic serine endoprotease DegP-like loss of pathogenicity
DKMPNCBD_00255 PHI:9334 map 89.8 1.9e-141 1 264 1.0000 1.0000 rodents colitis effector protein effector (plant avirulence determinant)
DKMPNCBD_00281 PHI:8514 nlpE 79.3 3.9e-109 2 233 0.9831 0.9957 rodents colitis outer-membrane lipoprotein unaffected pathogenicity
DKMPNCBD_00312 PHI:12052 icmF 78.2 0 1 1174 1.0000 1.0000 eukaryotes colibacillosis type VI secretion system protein unaffected pathogenicity
DKMPNCBD_00315 PHI:4559 T6SS2 90.2 0 1 919 1.0000 1.0000 birds meningitis type VI secretion systems (T6SSs) effectors effector (plant avirulence determinant)
DKMPNCBD_00316 PHI:12050 impK 98 8.1e-145 1 253 1.0000 1.0000 eukaryotes colibacillosis type VI secretion system protein unaffected pathogenicity
DKMPNCBD_00323 PHI:12051 evpB 99.8 1.8e-289 1 491 1.0000 1.0000 eukaryotes colibacillosis type VI secretion system protein unaffected pathogenicity
DKMPNCBD_00326 PHI:8554 hcp2 100 3.7e-101 1 172 1.0000 1.0000 birds avian colibacillosis hemolysin co-regulation protein reduced virulence
DKMPNCBD_00327 PHI:4560 VgrG 99.2 0 1 713 1.0000 1.0000 birds meningitis type VI secretion systems (T6SSs) effectors effector (plant avirulence determinant)
DKMPNCBD_00345 PHI:2647 ivy 99.4 2.6e-85 1 157 1.0000 1.0000 birds colibacillosis; cellulitis; swollen head syndrome lysozyme inhibitor unaffected pathogenicity






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
PEHEEDOF_00085 AIZ54166.1|GH23 100 0 1 645 1 1
PEHEEDOF_00181 AOM48085.1|GT28 100 9.67e-247 1 347 1 1
PEHEEDOF_00187 QFX37759.1|CE11 100 1.05e-222 1 305 1 1
PEHEEDOF_00238 ACI71325.1|GT51 100 0 1 844 1 1
PEHEEDOF_00270 AWN67334.1|GT19 100 1.02e-277 1 382 1 1
PEHEEDOF_00301 AWF26648.1|CBM50|GH23 100 1.39e-294 1 406 1 1
DKMPNCBD_00085 AIZ54166.1|GH23 100 0 1 645 1 1
DKMPNCBD_00181 AOM48085.1|GT28 100 9.67e-247 1 347 1 1
DKMPNCBD_00187 QFX37759.1|CE11 100 1.05e-222 1 305 1 1
DKMPNCBD_00238 ACI71325.1|GT51 100 0 1 844 1 1
DKMPNCBD_00270 AWN67334.1|GT19 100 1.02e-277 1 382 1 1
DKMPNCBD_00301 AWF26648.1|CBM50|GH23 100 1.39e-294 1 406 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
PEHEEDOF_00004 1.B.11.3.9 99.2 0 1 878 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.11 The Outer Membrane Fimbrial Usher Porin (FUP) Family
PEHEEDOF_00009 2.A.8.1.3 100 1.3e-235 1 447 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.8 The Gluconate:H+ Symporter (GntP) Family
PEHEEDOF_00018 9.B.156.1.1 98.7 1.4e-78 1 153 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.156 The Putative 4-10 TMS Permease (4-10P) Family
PEHEEDOF_00019 9.A.5.4.2 99.1 9.6e-121 1 227 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.A Recognized transporters of unknown biochemical mechanism 9.A.5 The Putative Arginine Transporter (ArgW) Family
PEHEEDOF_00021 2.A.1.51.2 90.4 7.5e-190 1 387 0.9872 0.9872 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
PEHEEDOF_00027 2.A.1.2.52 97.8 4.6e-222 1 410 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
PEHEEDOF_00034 2.A.114.1.10 96.4 0 1 716 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.114 The Putative Peptide Transporter Carbon Starvation CstA (CstA) Family
PEHEEDOF_00038 2.A.1.14.9 87.8 3.1e-235 1 458 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
PEHEEDOF_00047 2.A.1.14.33 99.6 7.9e-260 1 453 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
PEHEEDOF_00055 2.A.79.2.1 99.2 1.8e-142 22 277 0.9242 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.79 The Threonine/Serine Exporter (ThrE) Family
PEHEEDOF_00068 8.A.213.1.2 100 1.4e-99 1 201 1.0000 1.0000 8 Accessory Factors Involved in Transport 8.A Auxiliary transport proteins 8.A.213 The Bon Domain-containing Protein (Bon DP) Family
PEHEEDOF_00083 4.B.1.1.1 94.9 9.8e-233 1 409 0.9976 1.7113 4 Group Translocators 4.B Nicotinamide ribonucleoside uptake transporters 4.B.1 The Nicotinamide Ribonucleoside (NR) Uptake Permease (PnuC) Family
PEHEEDOF_00102 2.A.25.1.10 99.2 4.9e-268 1 476 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.25 The Alanine or Glycine:Cation Symporter (AGCS) Family
PEHEEDOF_00105 2.A.96.1.1 100 3.7e-102 1 188 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.96 The Acetate Uptake Transporter (AceTr) Family
PEHEEDOF_00108 1.A.33.1.2 100 0 1 638 1.0000 1.0000 1 Channels/Pores 1.A α-Type Channels 1.A.33 The Cation Channel-forming Heat Shock Protein-70 (Hsp70) Family
PEHEEDOF_00110 1.E.53.1.1 100 3.6e-20 1 50 1.0000 1.0000 1 Channels/Pores 1.E Holins 1.E.53 The Toxic Hok/Gef Protein (Hok/Gef) Family
PEHEEDOF_00111 2.A.33.1.1 99.5 3.8e-210 1 388 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.33 The NhaA Na+:H+ Antiporter (NhaA) Family
PEHEEDOF_00129 4.C.1.1.6 97.9 3.4e-307 1 517 1.0000 1.0000 4 Group Translocators 4.C Acyl CoA ligase-coupled transporters 4.C.1 The Fatty Acid Group Translocation (FAT) Family
PEHEEDOF_00132 2.A.15.2.1 100 7.4e-299 1 504 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.15 The Betaine/Carnitine/Choline Transporter (BCCT) Family
PEHEEDOF_00137 2.A.1.1.114 100 6.4e-254 1 443 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
PEHEEDOF_00138 2.A.37.1.1 100 1.2e-107 1 176 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.37 The Monovalent Cation:Proton Antiporter-2 (CPA2) Family
PEHEEDOF_00139 2.A.37.1.1 99.5 0 1 620 1.0000 3.5227 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.37 The Monovalent Cation:Proton Antiporter-2 (CPA2) Family
PEHEEDOF_00148 1.B.42.1.2 100 0 1 784 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.42 The Outer Membrane Lipopolysaccharide Export Porin (LPS-EP) Family
PEHEEDOF_00158 3.A.1.19.1 98.3 6.1e-123 1 232 1.0000 0.7095 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
PEHEEDOF_00159 3.A.1.19.1 98.5 3.5e-299 1 536 1.0000 1.6391 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
PEHEEDOF_00160 3.A.1.19.1 99.1 1.1e-189 1 327 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
PEHEEDOF_00163 2.A.1.20.1 99.7 5.7e-214 1 392 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
PEHEEDOF_00178 9.B.146.1.6 100 1.3e-204 1 360 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.146 The Putative Undecaprenyl-phosphate N-Acetylglucosaminyl Transferase (MurG) Family
PEHEEDOF_00180 2.A.103.1.1 100 2.7e-230 1 414 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.103 The Bacterial Murein Precursor Exporter (MPE) Family
PEHEEDOF_00189 3.A.5.1.1 100 0 1 901 1.0000 4.3738 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.5 The General Secretory Pathway (Sec) Family
PEHEEDOF_00200 9.B.125.1.1 100 2.6e-160 1 284 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.125 The AmpE/CobD (AmpE/CobD) Family
PEHEEDOF_00201 2.A.3.1.3 100 1e-254 1 456 1.0000 0.9978 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.3 The Amino Acid-Polyamine-Organocation (APC) Family
PEHEEDOF_00211 8.A.2.1.3 100 3.5e-54 1 102 1.0000 0.8870 8 Accessory Factors Involved in Transport 8.A Auxiliary transport proteins 8.A.2 The Secretin Auxiliary Lipoprotein (SAL) Family
PEHEEDOF_00212 1.B.76.1.8 99.4 1.4e-308 1 516 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.76 The Copper Resistance Putative Porin (CopB) Family
PEHEEDOF_00213 9.B.306.4.2 99.6 0 1 796 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.306 The Putative Calcium Binding Protein with Similarity to the C-termini of Anoctamins (1.A.17.5) (CBP) Family
PEHEEDOF_00216 3.A.1.105.17 100 7.2e-172 1 308 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
PEHEEDOF_00217 3.A.1.105.17 100 8.5e-142 1 256 1.0000 0.8312 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
PEHEEDOF_00228 1.B.11.3.3 97.7 0 1 866 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.11 The Outer Membrane Fimbrial Usher Porin (FUP) Family
PEHEEDOF_00239 1.B.14.1.2 99.9 0 1 747 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.14 The Outer Membrane Receptor (OMR) Family
PEHEEDOF_00240 3.A.1.14.3 100 9.4e-152 1 265 1.0000 0.8953 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
PEHEEDOF_00241 3.A.1.14.3 99.3 1.6e-171 1 296 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
PEHEEDOF_00242 3.A.1.14.3 99.2 0 1 660 1.0000 2.2297 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
PEHEEDOF_00244 2.A.49.5.1 100 3e-262 1 473 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.49 The Chloride Carrier/Channel (ClC) Family
PEHEEDOF_00246 1.A.62.2.2 86.7 9.7e-96 1 203 0.9807 0.9951 1 Channels/Pores 1.A α-Type Channels 1.A.62 The Homotrimeric Cation Channel (TRIC) Family
PEHEEDOF_00247 3.A.1.13.1 81.2 2e-122 1 266 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
PEHEEDOF_00264 9.B.149.2.3 100 2.3e-259 1 450 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.149 The M50 Peptidase (M50-P) Family
PEHEEDOF_00265 1.B.33.1.3 100 0 1 810 1.0000 2.0663 1 Channels/Pores 1.B β-Barrel Porins 1.B.33 The Outer Membrane Protein Insertion Porin (Bam Complex) (OmpIP) Family
PEHEEDOF_00287 3.A.1.24.1 99.6 3.6e-151 1 271 1.0000 1.2488 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
PEHEEDOF_00288 3.A.1.24.1 100 1.7e-111 1 217 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
PEHEEDOF_00289 3.A.1.24.1 99.7 2.8e-193 1 343 1.0000 1.5806 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DKMPNCBD_00004 1.B.11.3.9 99.2 0 1 878 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.11 The Outer Membrane Fimbrial Usher Porin (FUP) Family
DKMPNCBD_00009 2.A.8.1.3 100 1.3e-235 1 447 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.8 The Gluconate:H+ Symporter (GntP) Family
DKMPNCBD_00018 9.B.156.1.1 98.7 1.4e-78 1 153 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.156 The Putative 4-10 TMS Permease (4-10P) Family
DKMPNCBD_00019 9.A.5.4.2 99.1 9.6e-121 1 227 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.A Recognized transporters of unknown biochemical mechanism 9.A.5 The Putative Arginine Transporter (ArgW) Family
DKMPNCBD_00021 2.A.1.51.2 90.4 7.5e-190 1 387 0.9872 0.9872 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
DKMPNCBD_00027 2.A.1.2.52 97.8 4.6e-222 1 410 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
DKMPNCBD_00034 2.A.114.1.10 96.4 0 1 716 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.114 The Putative Peptide Transporter Carbon Starvation CstA (CstA) Family
DKMPNCBD_00038 2.A.1.14.9 87.8 3.1e-235 1 458 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
DKMPNCBD_00047 2.A.1.14.33 99.6 7.9e-260 1 453 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
DKMPNCBD_00055 2.A.79.2.1 99.2 1.8e-142 22 277 0.9242 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.79 The Threonine/Serine Exporter (ThrE) Family
DKMPNCBD_00068 8.A.213.1.2 100 1.4e-99 1 201 1.0000 1.0000 8 Accessory Factors Involved in Transport 8.A Auxiliary transport proteins 8.A.213 The Bon Domain-containing Protein (Bon DP) Family
DKMPNCBD_00083 4.B.1.1.1 94.9 9.8e-233 1 409 0.9976 1.7113 4 Group Translocators 4.B Nicotinamide ribonucleoside uptake transporters 4.B.1 The Nicotinamide Ribonucleoside (NR) Uptake Permease (PnuC) Family
DKMPNCBD_00102 2.A.25.1.10 99.2 4.9e-268 1 476 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.25 The Alanine or Glycine:Cation Symporter (AGCS) Family
DKMPNCBD_00105 2.A.96.1.1 100 3.7e-102 1 188 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.96 The Acetate Uptake Transporter (AceTr) Family
DKMPNCBD_00108 1.A.33.1.2 100 0 1 638 1.0000 1.0000 1 Channels/Pores 1.A α-Type Channels 1.A.33 The Cation Channel-forming Heat Shock Protein-70 (Hsp70) Family
DKMPNCBD_00110 1.E.53.1.1 100 3.6e-20 1 50 1.0000 1.0000 1 Channels/Pores 1.E Holins 1.E.53 The Toxic Hok/Gef Protein (Hok/Gef) Family
DKMPNCBD_00111 2.A.33.1.1 99.5 3.8e-210 1 388 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.33 The NhaA Na+:H+ Antiporter (NhaA) Family
DKMPNCBD_00129 4.C.1.1.6 97.9 3.4e-307 1 517 1.0000 1.0000 4 Group Translocators 4.C Acyl CoA ligase-coupled transporters 4.C.1 The Fatty Acid Group Translocation (FAT) Family
DKMPNCBD_00132 2.A.15.2.1 100 7.4e-299 1 504 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.15 The Betaine/Carnitine/Choline Transporter (BCCT) Family
DKMPNCBD_00137 2.A.1.1.114 100 6.4e-254 1 443 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
DKMPNCBD_00138 2.A.37.1.1 100 1.2e-107 1 176 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.37 The Monovalent Cation:Proton Antiporter-2 (CPA2) Family
DKMPNCBD_00139 2.A.37.1.1 99.5 0 1 620 1.0000 3.5227 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.37 The Monovalent Cation:Proton Antiporter-2 (CPA2) Family
DKMPNCBD_00148 1.B.42.1.2 100 0 1 784 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.42 The Outer Membrane Lipopolysaccharide Export Porin (LPS-EP) Family
DKMPNCBD_00158 3.A.1.19.1 98.3 6.1e-123 1 232 1.0000 0.7095 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DKMPNCBD_00159 3.A.1.19.1 98.5 3.5e-299 1 536 1.0000 1.6391 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DKMPNCBD_00160 3.A.1.19.1 99.1 1.1e-189 1 327 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DKMPNCBD_00163 2.A.1.20.1 99.7 5.7e-214 1 392 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.1 The Major Facilitator Superfamily (MFS)
DKMPNCBD_00178 9.B.146.1.6 100 1.3e-204 1 360 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.146 The Putative Undecaprenyl-phosphate N-Acetylglucosaminyl Transferase (MurG) Family
DKMPNCBD_00180 2.A.103.1.1 100 2.7e-230 1 414 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.103 The Bacterial Murein Precursor Exporter (MPE) Family
DKMPNCBD_00189 3.A.5.1.1 100 0 1 901 1.0000 4.3738 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.5 The General Secretory Pathway (Sec) Family
DKMPNCBD_00200 9.B.125.1.1 100 2.6e-160 1 284 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.125 The AmpE/CobD (AmpE/CobD) Family
DKMPNCBD_00201 2.A.3.1.3 100 1e-254 1 456 1.0000 0.9978 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.3 The Amino Acid-Polyamine-Organocation (APC) Family
DKMPNCBD_00211 8.A.2.1.3 100 3.5e-54 1 102 1.0000 0.8870 8 Accessory Factors Involved in Transport 8.A Auxiliary transport proteins 8.A.2 The Secretin Auxiliary Lipoprotein (SAL) Family
DKMPNCBD_00212 1.B.76.1.8 99.4 1.4e-308 1 516 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.76 The Copper Resistance Putative Porin (CopB) Family
DKMPNCBD_00213 9.B.306.4.2 99.6 0 1 796 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.306 The Putative Calcium Binding Protein with Similarity to the C-termini of Anoctamins (1.A.17.5) (CBP) Family
DKMPNCBD_00216 3.A.1.105.17 100 7.2e-172 1 308 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DKMPNCBD_00217 3.A.1.105.17 100 8.5e-142 1 256 1.0000 0.8312 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DKMPNCBD_00228 1.B.11.3.3 97.7 0 1 866 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.11 The Outer Membrane Fimbrial Usher Porin (FUP) Family
DKMPNCBD_00239 1.B.14.1.2 99.9 0 1 747 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.14 The Outer Membrane Receptor (OMR) Family
DKMPNCBD_00240 3.A.1.14.3 100 9.4e-152 1 265 1.0000 0.8953 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DKMPNCBD_00241 3.A.1.14.3 99.3 1.6e-171 1 296 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DKMPNCBD_00242 3.A.1.14.3 99.2 0 1 660 1.0000 2.2297 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DKMPNCBD_00244 2.A.49.5.1 100 3e-262 1 473 1.0000 1.0000 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.49 The Chloride Carrier/Channel (ClC) Family
DKMPNCBD_00246 1.A.62.2.2 86.7 9.7e-96 1 203 0.9807 0.9951 1 Channels/Pores 1.A α-Type Channels 1.A.62 The Homotrimeric Cation Channel (TRIC) Family
DKMPNCBD_00247 3.A.1.13.1 81.2 2e-122 1 266 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DKMPNCBD_00264 9.B.149.2.3 100 2.3e-259 1 450 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.149 The M50 Peptidase (M50-P) Family
DKMPNCBD_00265 1.B.33.1.3 100 0 1 810 1.0000 2.0663 1 Channels/Pores 1.B β-Barrel Porins 1.B.33 The Outer Membrane Protein Insertion Porin (Bam Complex) (OmpIP) Family
DKMPNCBD_00287 3.A.1.24.1 99.6 3.6e-151 1 271 1.0000 1.2488 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DKMPNCBD_00288 3.A.1.24.1 100 1.7e-111 1 217 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
DKMPNCBD_00289 3.A.1.24.1 99.7 2.8e-193 1 343 1.0000 1.5806 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily