Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C372
  Reference Plasmid   NZ_AP023325.1
  Reference Plasmid Size   44333
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0086916 LKKGCNKI_00005 126 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -1860A>G None
M0086917 LKKGCNKI_00054 42821 4 Skin 0.50 protein_coding synonymous_variant LOW 450T>C Asp150Asp
M0086918 LKKGCNKI_00054 42903 5 Skin 0.63 protein_coding missense_variant MODERATE 368G>A Arg123Gln
M0086919 LKKGCNKI_00054 43195 4 Skin 0.50 protein_coding missense_variant MODERATE 76G>A Asp26Asn
M0086920 LKKGCNKI_00017 13083 3 Skin 0.38 protein_coding missense_variant MODERATE 1357A>G Ser453Gly
M0086921 LKKGCNKI_00019 14328 4 Skin 0.50 protein_coding missense_variant MODERATE 295C>T Arg99Trp
M0086922 LKKGCNKI_00019 14329 4 Skin 0.50 protein_coding synonymous_variant LOW 294A>C Pro98Pro
M0086923 LKKGCNKI_00018 17771 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -3911T>C None
M0086924 LKKGCNKI_00024 18157 4 Skin 0.50 protein_coding missense_variant MODERATE 313C>T Arg105Trp
M0086925 LKKGCNKI_00019 19372 4 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -4750T>C None
M0086926 LKKGCNKI_00020 19712 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4427C>T None
M0086927 LKKGCNKI_00020 19713 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4428A>C None
M0086928 LKKGCNKI_00020 19738 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -4453G>C None
M0086929 LKKGCNKI_00022 20419 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -3501C>T None
M0086930 LKKGCNKI_00022 20420 3 Skin 0.38 protein_coding upstream_gene_variant MODIFIER -3502A>C None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term