Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C402
  Reference Plasmid   NZ_CP005191.1
  Reference Plasmid Size   287488
  Reference Plasmid GC Content   0.63
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0087090 FHEFCKPH_00108 88779 5 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -4686C>T None
M0087091 FHEFCKPH_00108 88811 5 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -4718A>C None
M0087092 FHEFCKPH_00108 88831 5 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -4738G>A None
M0087093 FHEFCKPH_00108 88895 5 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -4802T>A None
M0087094 FHEFCKPH_00118 89060 5 Skin 0.33 protein_coding synonymous_variant LOW 102A>G Glu34Glu
M0087095 FHEFCKPH_00118 89165 5 Skin 0.33 protein_coding synonymous_variant LOW 207T>C Arg69Arg
M0087096 FHEFCKPH_00118 89166 5 Skin 0.33 protein_coding missense_variant MODERATE 208A>G Ile70Val
M0087097 FHEFCKPH_00118 89168 5 Skin 0.33 protein_coding synonymous_variant LOW 210A>C Ile70Ile
M0087098 FHEFCKPH_00118 89273 5 Skin 0.33 protein_coding synonymous_variant LOW 315G>T Leu105Leu
M0087099 FHEFCKPH_00118 89399 5 Skin 0.33 protein_coding synonymous_variant LOW 441T>C Thr147Thr
M0087100 FHEFCKPH_00118 89429 5 Skin 0.33 protein_coding synonymous_variant LOW 471C>T Leu157Leu
M0087101 FHEFCKPH_00118 89525 5 Skin 0.33 protein_coding synonymous_variant LOW 567G>C Ala189Ala
M0087102 FHEFCKPH_00118 89543 4 Skin 0.27 protein_coding synonymous_variant LOW 585T>C Gly195Gly
M0087103 FHEFCKPH_00118 89595 5 Skin 0.33 protein_coding missense_variant MODERATE 637A>G Asn213Asp
M0087104 FHEFCKPH_00118 89618 5 Skin 0.33 protein_coding synonymous_variant LOW 660C>T Phe220Phe
M0087105 FHEFCKPH_00118 89642 5 Skin 0.33 protein_coding synonymous_variant LOW 684T>C Cys228Cys
M0087106 FHEFCKPH_00118 89660 5 Skin 0.33 protein_coding synonymous_variant LOW 702T>C Leu234Leu
M0087107 FHEFCKPH_00118 89762 5 Skin 0.33 protein_coding synonymous_variant LOW 804C>A Gly268Gly
M0087108 FHEFCKPH_00118 89777 5 Skin 0.33 protein_coding synonymous_variant LOW 819T>C Val273Val
M0087109 FHEFCKPH_00118 89834 5 Skin 0.33 protein_coding synonymous_variant LOW 876A>G Arg292Arg
M0087110 FHEFCKPH_00118 89845 5 Skin 0.33 protein_coding missense_variant MODERATE 887G>A Arg296His
M0087111 FHEFCKPH_00118 90023 5 Skin 0.33 protein_coding synonymous_variant LOW 1065C>T Ile355Ile
M0087112 FHEFCKPH_00118 90041 5 Skin 0.33 protein_coding synonymous_variant LOW 1083A>G Pro361Pro
M0087113 FHEFCKPH_00118 90077 5 Skin 0.33 protein_coding synonymous_variant LOW 1119T>C Ser373Ser
M0087114 FHEFCKPH_00118 90095 5 Skin 0.33 protein_coding synonymous_variant LOW 1137T>C His379His
M0087115 FHEFCKPH_00118 90140 5 Skin 0.33 protein_coding synonymous_variant LOW 1182C>T Pro394Pro
M0087116 FHEFCKPH_00118 90146 5 Skin 0.33 protein_coding synonymous_variant LOW 1188A>G Ala396Ala
M0087117 FHEFCKPH_00118 90176 5 Skin 0.33 protein_coding synonymous_variant LOW 1218C>G Leu406Leu
M0087118 FHEFCKPH_00118 90323 5 Skin 0.33 protein_coding synonymous_variant LOW 1365T>A Ala455Ala
M0087119 FHEFCKPH_00118 90332 5 Skin 0.33 protein_coding missense_variant MODERATE 1374C>A Ser458Arg
M0087120 FHEFCKPH_00118 90402 5 Skin 0.33 protein_coding missense_variant MODERATE 1444G>A Ala482Thr
M0087121 FHEFCKPH_00118 90413 5 Skin 0.33 protein_coding synonymous_variant LOW 1455A>T Pro485Pro
M0087122 FHEFCKPH_00118 90438 5 Skin 0.33 protein_coding synonymous_variant LOW 1480C>T Leu494Leu
M0087123 FHEFCKPH_00118 90459 5 Skin 0.33 protein_coding missense_variant MODERATE 1501C>T His501Tyr
M0087124 FHEFCKPH_00119 90481 5 Skin 0.33 protein_coding synonymous_variant LOW 18T>C Asp6Asp
M0087125 FHEFCKPH_00119 90496 5 Skin 0.33 protein_coding synonymous_variant LOW 33A>G Val11Val
M0087126 FHEFCKPH_00119 90532 5 Skin 0.33 protein_coding synonymous_variant LOW 69C>T Ser23Ser
M0087127 FHEFCKPH_00119 90552 5 Skin 0.33 protein_coding missense_variant MODERATE 89A>G His30Arg
M0087128 FHEFCKPH_00119 90628 5 Skin 0.33 protein_coding synonymous_variant LOW 165T>C Ala55Ala
M0087129 FHEFCKPH_00119 90715 5 Skin 0.33 protein_coding synonymous_variant LOW 252C>A Ala84Ala
M0087130 FHEFCKPH_00119 90777 5 Skin 0.33 protein_coding missense_variant MODERATE 314A>G Asn105Ser
M0087131 FHEFCKPH_00119 90835 5 Skin 0.33 protein_coding synonymous_variant LOW 372C>T Ala124Ala
M0087132 FHEFCKPH_00119 90844 5 Skin 0.33 protein_coding synonymous_variant LOW 381C>T Gly127Gly
M0087133 FHEFCKPH_00119 90935 5 Skin 0.33 protein_coding synonymous_variant LOW 472T>C Leu158Leu
M0087134 FHEFCKPH_00119 90937 5 Skin 0.33 protein_coding synonymous_variant LOW 474G>A Leu158Leu
M0087135 FHEFCKPH_00119 91018 5 Skin 0.33 protein_coding synonymous_variant LOW 555A>G Glu185Glu
M0087136 FHEFCKPH_00119 91126 5 Skin 0.33 protein_coding synonymous_variant LOW 663C>T Ala221Ala
M0087137 FHEFCKPH_00119 91130 5 Skin 0.33 protein_coding missense_variant MODERATE 667G>A Ala223Thr
M0087138 FHEFCKPH_00119 91167 5 Skin 0.33 protein_coding missense_variant MODERATE 704C>T Thr235Ile
M0087139 FHEFCKPH_00119 91201 5 Skin 0.33 protein_coding synonymous_variant LOW 738G>A Lys246Lys
M0087140 FHEFCKPH_00119 91219 5 Skin 0.33 protein_coding synonymous_variant LOW 756C>T Arg252Arg
M0087141 FHEFCKPH_00119 91246 5 Skin 0.33 protein_coding synonymous_variant LOW 783C>G Pro261Pro
M0087142 FHEFCKPH_00120 91367 5 Skin 0.33 protein_coding synonymous_variant LOW 45A>G Gln15Gln
M0087143 FHEFCKPH_00120 91388 5 Skin 0.33 protein_coding synonymous_variant LOW 66C>T Arg22Arg
M0087144 FHEFCKPH_00120 91435 5 Skin 0.33 protein_coding missense_variant MODERATE 113T>C Leu38Pro
M0087145 FHEFCKPH_00120 91494 5 Skin 0.33 protein_coding stop_gained HIGH 172A>T Lys58*






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
FHEFCKPH_00149 Arsenic (As) 71.1 2.7e-84 18 232 0.8385 0.9160 prediction
FHEFCKPH_00150 Arsenic (As) 92.4 3.5e-180 1 353 0.9888 0.9972 prediction
FHEFCKPH_00287 Chromium (Cr) 77.3 1e-98 27 242 0.8889 0.9643 prediction
FHEFCKPH_00290 Mercury (Hg) 100 2.7e-75 1 140 1.0000 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
FHEFCKPH_00051 AMK21347.1|GH23 100 2.39e-225 1 317 1 1
FHEFCKPH_00076 QYO62262.1|GH13 71.1 6.35e-152 3 338 0.6234 0.7494





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term