Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C422
  Reference Plasmid   NZ_CP011017.1
  Reference Plasmid Size   44826
  Reference Plasmid GC Content   0.30
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0164295 MFBNOOLJ_00049 43274 5 Gut 0.56 protein_coding missense_variant MODERATE 520G>A Glu174Lys
M0164296 MFBNOOLJ_00049 43455 5 Gut 0.56 protein_coding synonymous_variant LOW 339T>C Ser113Ser
M0164297 MFBNOOLJ_00049 43467 4 Gut 0.44 protein_coding synonymous_variant LOW 327T>C Phe109Phe
M0164298 MFBNOOLJ_00049 43587 3 Gut 0.33 protein_coding synonymous_variant LOW 207G>A Gly69Gly
M0164299 MFBNOOLJ_00049 43758 3 Gut 0.33 protein_coding synonymous_variant LOW 36C>A Val12Val
M0164300 MFBNOOLJ_00042 43811 4 Gut 0.44 protein_coding upstream_gene_variant MODIFIER -4704T>C None
M0164301 MFBNOOLJ_00047 41223 3 Gut 0.33 protein_coding synonymous_variant LOW 999C>A Ser333Ser
M0164302 MFBNOOLJ_00047 41265 3 Gut 0.33 protein_coding synonymous_variant LOW 957T>C Ser319Ser
M0164303 MFBNOOLJ_00047 41283 3 Gut 0.33 protein_coding synonymous_variant LOW 939C>T Ala313Ala
M0164304 MFBNOOLJ_00047 41469 3 Gut 0.33 protein_coding synonymous_variant LOW 753C>T Tyr251Tyr
M0164305 MFBNOOLJ_00047 41572 5 Gut 0.56 protein_coding missense_variant MODERATE 650T>C Val217Ala
M0164306 MFBNOOLJ_00047 41607 3 Gut 0.33 protein_coding synonymous_variant LOW 615T>G Gly205Gly
M0164307 MFBNOOLJ_00047 41676 5 Gut 0.56 protein_coding synonymous_variant LOW 546T>C Ile182Ile
M0164308 MFBNOOLJ_00047 41957 3 Gut 0.33 protein_coding missense_variant MODERATE 265A>G Ile89Val
M0164309 MFBNOOLJ_00047 41969 3 Gut 0.33 protein_coding synonymous_variant LOW 253C>T Leu85Leu
M0164310 MFBNOOLJ_00047 42018 5 Gut 0.56 protein_coding synonymous_variant LOW 204T>C Ser68Ser
M0164311 MFBNOOLJ_00047 42143 4 Gut 0.44 protein_coding synonymous_variant LOW 79T>C Leu27Leu
M0164312 MFBNOOLJ_00039 42230 5 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -4324C>T None
M0164313 MFBNOOLJ_00039 42280 5 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -4374A>C None
M0164314 MFBNOOLJ_00039 42281 5 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -4375A>G None
M0164315 MFBNOOLJ_00039 42274 4 Gut 0.44 protein_coding upstream_gene_variant MODIFIER -4368A>C None
M0164316 MFBNOOLJ_00039 42291 4 Gut 0.44 protein_coding upstream_gene_variant MODIFIER -4385G>A None
M0164317 MFBNOOLJ_00039 42292 4 Gut 0.44 protein_coding upstream_gene_variant MODIFIER -4386C>G None
M0164318 MFBNOOLJ_00039 42318 4 Gut 0.44 protein_coding upstream_gene_variant MODIFIER -4412T>C None
M0164319 MFBNOOLJ_00039 42327 4 Gut 0.44 protein_coding upstream_gene_variant MODIFIER -4421A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term