Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C424
  Reference Plasmid   NZ_CP011404.1
  Reference Plasmid Size   176951
  Reference Plasmid GC Content   0.32
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0164331 NEJIMKPK_00028 31224 3 Gut 0.06 protein_coding synonymous_variant LOW 24G>A Glu8Glu
M0164332 NEJIMKPK_00029 35816 3 Gut 0.06 protein_coding synonymous_variant LOW 4266G>A Gly1422Gly
M0164333 NEJIMKPK_00030 36269 4 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -21T>C None
M0164334 NEJIMKPK_00033 39306 3 Gut 0.06 protein_coding synonymous_variant LOW 15G>A Lys5Lys
M0164335 NEJIMKPK_00031 41415 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -3841A>G None
M0164336 NEJIMKPK_00036 41660 3 Gut 0.06 protein_coding missense_variant MODERATE 157T>C Ser53Pro
M0164337 NEJIMKPK_00036 41768 4 Gut 0.08 protein_coding missense_variant MODERATE 49T>C Cys17Arg
M0164338 NEJIMKPK_00037 41895 3 Gut 0.06 protein_coding missense_variant MODERATE 182A>G Glu61Gly
M0164339 NEJIMKPK_00037 42041 3 Gut 0.06 protein_coding synonymous_variant LOW 36C>T Asp12Asp
M0164340 NEJIMKPK_00039 43009 4 Gut 0.08 protein_coding synonymous_variant LOW 165G>A Ala55Ala
M0164341 NEJIMKPK_00039 43595 6 Gut 0.11 protein_coding missense_variant MODERATE 751A>G Thr251Ala
M0164342 NEJIMKPK_00043 47295 7 Gut 0.13 protein_coding missense_variant MODERATE 420A>G Ile140Met
M0164343 NEJIMKPK_00043 47759 7 Gut 0.13 protein_coding upstream_gene_variant MODIFIER -45A>G None
M0164344 NEJIMKPK_00047 51853 6 Gut 0.11 protein_coding missense_variant MODERATE 635A>G His212Arg
M0164345 NEJIMKPK_00048 52297 6 Gut 0.11 protein_coding missense_variant MODERATE 233G>A Arg78Lys
M0164346 NEJIMKPK_00049 54602 5 Gut 0.09 protein_coding missense_variant MODERATE 802A>G Thr268Ala
M0164347 NEJIMKPK_00051 56668 6 Gut 0.11 protein_coding upstream_gene_variant MODIFIER -76A>G None
M0164348 NEJIMKPK_00055 58417 3 Gut 0.06 protein_coding missense_variant MODERATE 187A>G Thr63Ala
M0164349 NEJIMKPK_00051 59832 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -3240G>A None
M0164350 NEJIMKPK_00051 60370 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -3778A>G None
M0164351 NEJIMKPK_00059 60531 5 Gut 0.09 protein_coding missense_variant MODERATE 179T>A Val60Asp
M0164352 NEJIMKPK_00060 61009 5 Gut 0.09 protein_coding missense_variant MODERATE 379T>C Ser127Pro
M0164353 NEJIMKPK_00060 61324 5 Gut 0.09 protein_coding missense_variant MODERATE 64A>G Asn22Asp
M0164354 NEJIMKPK_00061 61658 5 Gut 0.09 protein_coding missense_variant MODERATE 842C>T Thr281Ile
M0164355 NEJIMKPK_00061 61661 5 Gut 0.09 protein_coding missense_variant MODERATE 839T>C Ile280Thr
M0164356 NEJIMKPK_00062 62962 5 Gut 0.09 protein_coding missense_variant MODERATE 287C>T Thr96Met
M0164357 NEJIMKPK_00070 70294 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -484T>A None
M0164358 NEJIMKPK_00074 75831 5 Gut 0.09 protein_coding synonymous_variant LOW 492A>G Glu164Glu
M0164359 NEJIMKPK_00074 75834 5 Gut 0.09 protein_coding synonymous_variant LOW 489C>T Ser163Ser
M0164360 NEJIMKPK_00074 75854 5 Gut 0.09 protein_coding missense_variant MODERATE 469A>G Ile157Val
M0164361 NEJIMKPK_00074 75855 5 Gut 0.09 protein_coding synonymous_variant LOW 468G>A Ala156Ala
M0164362 NEJIMKPK_00074 75915 5 Gut 0.09 protein_coding synonymous_variant LOW 408G>A Arg136Arg
M0164363 NEJIMKPK_00074 75924 5 Gut 0.09 protein_coding synonymous_variant LOW 399C>T Ile133Ile
M0164364 NEJIMKPK_00074 75966 5 Gut 0.09 protein_coding synonymous_variant LOW 357T>C Cys119Cys
M0164365 NEJIMKPK_00074 75993 5 Gut 0.09 protein_coding synonymous_variant LOW 330A>G Pro110Pro
M0164366 NEJIMKPK_00074 76008 5 Gut 0.09 protein_coding synonymous_variant LOW 315C>T Asn105Asn
M0164367 NEJIMKPK_00074 76071 5 Gut 0.09 protein_coding synonymous_variant LOW 252A>G Lys84Lys
M0164368 NEJIMKPK_00074 76092 5 Gut 0.09 protein_coding synonymous_variant LOW 231T>C Thr77Thr
M0164369 NEJIMKPK_00072 76464 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -3326G>A None
M0164370 NEJIMKPK_00077 78915 5 Gut 0.09 protein_coding synonymous_variant LOW 672C>T Gly224Gly
M0164371 NEJIMKPK_00077 79290 5 Gut 0.09 protein_coding synonymous_variant LOW 297C>T Asn99Asn
M0164372 NEJIMKPK_00077 79293 5 Gut 0.09 protein_coding synonymous_variant LOW 294G>A Leu98Leu
M0164373 NEJIMKPK_00077 79296 5 Gut 0.09 protein_coding synonymous_variant LOW 291T>C Ser97Ser
M0164374 NEJIMKPK_00077 79311 5 Gut 0.09 protein_coding synonymous_variant LOW 276G>A Lys92Lys
M0164375 NEJIMKPK_00077 79314 5 Gut 0.09 protein_coding synonymous_variant LOW 273C>T Thr91Thr
M0164376 NEJIMKPK_00077 79329 5 Gut 0.09 protein_coding synonymous_variant LOW 258G>A Glu86Glu
M0164377 NEJIMKPK_00077 79353 5 Gut 0.09 protein_coding missense_variant MODERATE 234G>T Lys78Asn
M0164378 NEJIMKPK_00077 79397 5 Gut 0.09 protein_coding missense_variant MODERATE 190A>G Lys64Glu
M0164379 NEJIMKPK_00077 79431 5 Gut 0.09 protein_coding synonymous_variant LOW 156C>T Ser52Ser
M0164380 NEJIMKPK_00078 79665 5 Gut 0.09 protein_coding synonymous_variant LOW 1156C>T Leu386Leu
M0164381 NEJIMKPK_00078 79726 5 Gut 0.09 protein_coding synonymous_variant LOW 1095C>T Tyr365Tyr
M0164382 NEJIMKPK_00078 79729 5 Gut 0.09 protein_coding synonymous_variant LOW 1092G>A Leu364Leu
M0164383 NEJIMKPK_00078 79735 5 Gut 0.09 protein_coding synonymous_variant LOW 1086A>G Glu362Glu
M0164384 NEJIMKPK_00078 79762 5 Gut 0.09 protein_coding synonymous_variant LOW 1059G>A Ala353Ala
M0164385 NEJIMKPK_00078 79870 5 Gut 0.09 protein_coding synonymous_variant LOW 951T>C Gly317Gly
M0164386 NEJIMKPK_00078 79873 5 Gut 0.09 protein_coding synonymous_variant LOW 948A>G Lys316Lys
M0164387 NEJIMKPK_00078 79900 5 Gut 0.09 protein_coding synonymous_variant LOW 921C>T Gly307Gly
M0164388 NEJIMKPK_00078 79954 5 Gut 0.09 protein_coding synonymous_variant LOW 867C>T Gly289Gly
M0164389 NEJIMKPK_00078 79975 5 Gut 0.09 protein_coding synonymous_variant LOW 846T>C Asn282Asn
M0164390 NEJIMKPK_00078 79993 5 Gut 0.09 protein_coding synonymous_variant LOW 828C>T Ile276Ile
M0164391 NEJIMKPK_00078 80091 5 Gut 0.09 protein_coding synonymous_variant LOW 730T>C Leu244Leu
M0164392 NEJIMKPK_00078 80095 5 Gut 0.09 protein_coding synonymous_variant LOW 726T>C Ser242Ser
M0164393 NEJIMKPK_00078 80107 5 Gut 0.09 protein_coding synonymous_variant LOW 714T>A Gly238Gly
M0164394 NEJIMKPK_00078 80122 5 Gut 0.09 protein_coding synonymous_variant LOW 699T>C Ile233Ile
M0164395 NEJIMKPK_00078 80128 5 Gut 0.09 protein_coding synonymous_variant LOW 693T>C Ser231Ser
M0164396 NEJIMKPK_00078 80131 5 Gut 0.09 protein_coding synonymous_variant LOW 690C>T Asp230Asp
M0164397 NEJIMKPK_00078 80134 5 Gut 0.09 protein_coding synonymous_variant LOW 687A>G Arg229Arg
M0164398 NEJIMKPK_00078 80164 5 Gut 0.09 protein_coding synonymous_variant LOW 657C>T Ala219Ala
M0164399 NEJIMKPK_00078 80191 5 Gut 0.09 protein_coding synonymous_variant LOW 630T>A Val210Val
M0164400 NEJIMKPK_00078 80209 5 Gut 0.09 protein_coding synonymous_variant LOW 612C>A Arg204Arg
M0164401 NEJIMKPK_00078 80220 5 Gut 0.09 protein_coding missense_variant MODERATE 601A>G Asn201Asp
M0164402 NEJIMKPK_00078 80224 5 Gut 0.09 protein_coding synonymous_variant LOW 597C>T Ala199Ala
M0164403 NEJIMKPK_00078 80248 5 Gut 0.09 protein_coding synonymous_variant LOW 573C>T Ala191Ala
M0164404 NEJIMKPK_00078 80272 5 Gut 0.09 protein_coding synonymous_variant LOW 549T>A Thr183Thr
M0164405 NEJIMKPK_00078 80299 5 Gut 0.09 protein_coding synonymous_variant LOW 522G>A Ser174Ser
M0164406 NEJIMKPK_00078 80314 5 Gut 0.09 protein_coding synonymous_variant LOW 507G>T Thr169Thr
M0164407 NEJIMKPK_00078 80513 5 Gut 0.09 protein_coding missense_variant MODERATE 308A>G Asp103Gly
M0164408 NEJIMKPK_00078 80529 5 Gut 0.09 protein_coding synonymous_variant LOW 292C>T Leu98Leu
M0164409 NEJIMKPK_00078 80536 5 Gut 0.09 protein_coding synonymous_variant LOW 285G>A Glu95Glu
M0164410 NEJIMKPK_00078 80589 5 Gut 0.09 protein_coding missense_variant MODERATE 232A>G Ile78Val
M0164411 NEJIMKPK_00078 80620 5 Gut 0.09 protein_coding synonymous_variant LOW 201T>C Asp67Asp
M0164412 NEJIMKPK_00078 80657 5 Gut 0.09 protein_coding missense_variant MODERATE 164C>T Ala55Val
M0164413 NEJIMKPK_00078 80659 5 Gut 0.09 protein_coding synonymous_variant LOW 162T>C Thr54Thr
M0164414 NEJIMKPK_00078 80680 5 Gut 0.09 protein_coding synonymous_variant LOW 141C>T Asn47Asn
M0164415 NEJIMKPK_00078 80701 5 Gut 0.09 protein_coding synonymous_variant LOW 120G>A Lys40Lys
M0164416 NEJIMKPK_00079 81040 6 Gut 0.11 protein_coding missense_variant MODERATE 573A>G Ile191Met
M0164417 NEJIMKPK_00079 81394 4 Gut 0.08 protein_coding synonymous_variant LOW 219G>A Pro73Pro
M0164418 NEJIMKPK_00079 81424 5 Gut 0.09 protein_coding synonymous_variant LOW 189G>A Leu63Leu
M0164419 NEJIMKPK_00079 81541 4 Gut 0.08 protein_coding synonymous_variant LOW 72G>A Leu24Leu
M0164420 NEJIMKPK_00079 81550 5 Gut 0.09 protein_coding synonymous_variant LOW 63T>C Gly21Gly
M0164421 NEJIMKPK_00079 81553 5 Gut 0.09 protein_coding synonymous_variant LOW 60A>G Lys20Lys
M0164422 NEJIMKPK_00079 81556 4 Gut 0.08 protein_coding synonymous_variant LOW 57G>A Leu19Leu
M0164423 NEJIMKPK_00079 81559 5 Gut 0.09 protein_coding synonymous_variant LOW 54A>T Ile18Ile
M0164424 NEJIMKPK_00080 82562 5 Gut 0.09 protein_coding synonymous_variant LOW 948T>C Ile316Ile
M0164425 NEJIMKPK_00080 82814 5 Gut 0.09 protein_coding synonymous_variant LOW 696G>A Val232Val
M0164426 NEJIMKPK_00080 82856 5 Gut 0.09 protein_coding synonymous_variant LOW 654G>A Lys218Lys
M0164427 NEJIMKPK_00080 82884 6 Gut 0.11 protein_coding missense_variant MODERATE 626C>T Ala209Val
M0164428 NEJIMKPK_00080 82901 4 Gut 0.08 protein_coding synonymous_variant LOW 609C>T Tyr203Tyr
M0164429 NEJIMKPK_00080 82952 4 Gut 0.08 protein_coding synonymous_variant LOW 558G>A Val186Val
M0164430 NEJIMKPK_00080 82962 4 Gut 0.08 protein_coding missense_variant MODERATE 548G>A Ser183Asn
M0164431 NEJIMKPK_00080 83024 5 Gut 0.09 protein_coding synonymous_variant LOW 486G>A Thr162Thr
M0164432 NEJIMKPK_00080 83060 5 Gut 0.09 protein_coding synonymous_variant LOW 450A>T Gly150Gly
M0164433 NEJIMKPK_00080 83066 5 Gut 0.09 protein_coding synonymous_variant LOW 444A>G Lys148Lys
M0164434 NEJIMKPK_00080 83081 4 Gut 0.08 protein_coding synonymous_variant LOW 429A>G Lys143Lys
M0164435 NEJIMKPK_00080 83132 4 Gut 0.08 protein_coding synonymous_variant LOW 378T>C Tyr126Tyr
M0164436 NEJIMKPK_00080 83219 5 Gut 0.09 protein_coding synonymous_variant LOW 291A>T Ala97Ala
M0164437 NEJIMKPK_00080 83267 5 Gut 0.09 protein_coding synonymous_variant LOW 243T>C Gly81Gly
M0164438 NEJIMKPK_00080 83297 5 Gut 0.09 protein_coding synonymous_variant LOW 213C>T Gly71Gly
M0164439 NEJIMKPK_00080 83354 5 Gut 0.09 protein_coding synonymous_variant LOW 156A>C Thr52Thr
M0164440 NEJIMKPK_00080 83401 5 Gut 0.09 protein_coding synonymous_variant LOW 109C>T Leu37Leu
M0164441 NEJIMKPK_00080 83428 5 Gut 0.09 protein_coding missense_variant MODERATE 82G>A Gly28Ser
M0164442 NEJIMKPK_00080 83438 6 Gut 0.11 protein_coding synonymous_variant LOW 72C>T Gly24Gly
M0164443 NEJIMKPK_00080 83458 5 Gut 0.09 protein_coding missense_variant MODERATE 52A>G Ile18Val
M0164444 NEJIMKPK_00080 83468 5 Gut 0.09 protein_coding synonymous_variant LOW 42C>T Ser14Ser
M0164445 NEJIMKPK_00077 83520 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -3934G>A None
M0164446 NEJIMKPK_00077 83532 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -3946T>C None
M0164447 NEJIMKPK_00077 83576 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -3990T>C None
M0164448 NEJIMKPK_00077 83735 6 Gut 0.11 protein_coding upstream_gene_variant MODIFIER -4149C>T None
M0164449 NEJIMKPK_00077 83742 6 Gut 0.11 protein_coding upstream_gene_variant MODIFIER -4156G>A None
M0164450 NEJIMKPK_00077 83750 6 Gut 0.11 protein_coding upstream_gene_variant MODIFIER -4164A>C None
M0164451 NEJIMKPK_00077 83758 6 Gut 0.11 protein_coding upstream_gene_variant MODIFIER -4172C>T None
M0164452 NEJIMKPK_00090 94388 6 Gut 0.11 protein_coding missense_variant MODERATE 761T>C Val254Ala
M0164453 NEJIMKPK_00092 96320 4 Gut 0.08 protein_coding missense_variant MODERATE 631G>A Asp211Asn
M0164454 NEJIMKPK_00088 96969 4 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -4927C>T None
M0164455 NEJIMKPK_00088 96983 4 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -4941G>A None
M0164456 NEJIMKPK_00088 96996 4 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -4954A>C None
M0164457 NEJIMKPK_00093 97347 4 Gut 0.08 protein_coding synonymous_variant LOW 195A>G Leu65Leu
M0164458 NEJIMKPK_00093 97944 4 Gut 0.08 protein_coding synonymous_variant LOW 792T>C His264His
M0164459 NEJIMKPK_00135 143253 5 Gut 0.09 protein_coding synonymous_variant LOW 72T>C Ala24Ala
M0164460 NEJIMKPK_00137 143795 3 Gut 0.06 protein_coding synonymous_variant LOW 84C>T His28His
M0164461 NEJIMKPK_00131 144563 4 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -4600T>G None
M0164462 NEJIMKPK_00131 144638 4 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -4675C>T None
M0164463 NEJIMKPK_00132 145001 4 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -3491A>G None
M0164464 NEJIMKPK_00132 145123 6 Gut 0.11 protein_coding upstream_gene_variant MODIFIER -3613C>T None
M0164465 NEJIMKPK_00140 146427 4 Gut 0.08 protein_coding missense_variant MODERATE 151A>G Asn51Asp
M0164466 NEJIMKPK_00140 147092 6 Gut 0.11 protein_coding synonymous_variant LOW 816A>G Ala272Ala
M0164467 NEJIMKPK_00141 147723 6 Gut 0.11 protein_coding missense_variant MODERATE 1022A>G Asn341Ser
M0164468 NEJIMKPK_00141 147930 4 Gut 0.08 protein_coding missense_variant MODERATE 815T>G Val272Gly
M0164469 NEJIMKPK_00141 148023 4 Gut 0.08 protein_coding missense_variant MODERATE 722A>G Tyr241Cys
M0164470 NEJIMKPK_00141 148423 4 Gut 0.08 protein_coding missense_variant MODERATE 322G>A Val108Met
M0164471 NEJIMKPK_00142 149082 6 Gut 0.11 protein_coding missense_variant MODERATE 563A>G Glu188Gly
M0164472 NEJIMKPK_00141 150081 4 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -1337A>G None
M0164473 NEJIMKPK_00141 150195 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -1451C>T None
M0164474 NEJIMKPK_00145 151322 4 Gut 0.08 protein_coding synonymous_variant LOW 45T>C Asn15Asn
M0164475 NEJIMKPK_00150 155578 4 Gut 0.08 protein_coding missense_variant MODERATE 1666A>G Ser556Gly
M0164476 NEJIMKPK_00151 157843 5 Gut 0.09 protein_coding missense_variant MODERATE 335G>T Gly112Val
M0164477 NEJIMKPK_00153 159426 4 Gut 0.08 protein_coding missense_variant MODERATE 118G>A Val40Ile
M0164478 NEJIMKPK_00154 159653 6 Gut 0.11 protein_coding missense_variant MODERATE 71A>G Glu24Gly
M0164479 NEJIMKPK_00154 159788 4 Gut 0.08 protein_coding missense_variant MODERATE 206G>A Gly69Glu
M0164480 NEJIMKPK_00154 159804 6 Gut 0.11 protein_coding synonymous_variant LOW 222C>T Pro74Pro
M0164481 NEJIMKPK_00154 160107 3 Gut 0.06 protein_coding missense_variant MODERATE 525C>A Asn175Lys
M0164482 NEJIMKPK_00154 160402 4 Gut 0.08 protein_coding missense_variant MODERATE 820G>A Ala274Thr
M0164483 NEJIMKPK_00154 160640 6 Gut 0.11 protein_coding missense_variant MODERATE 1058A>C Tyr353Ser
M0164484 NEJIMKPK_00156 161862 4 Gut 0.08 protein_coding missense_variant MODERATE 125T>C Ile42Thr
M0164485 NEJIMKPK_00158 162663 6 Gut 0.11 protein_coding synonymous_variant LOW 132T>C Tyr44Tyr
M0164486 NEJIMKPK_00159 165059 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -1506A>G None
M0164487 NEJIMKPK_00162 165789 4 Gut 0.08 protein_coding missense_variant MODERATE 85A>G Ile29Val
M0164488 NEJIMKPK_00165 167832 5 Gut 0.09 protein_coding synonymous_variant LOW 990G>A Leu330Leu
M0164489 NEJIMKPK_00166 168545 3 Gut 0.06 protein_coding synonymous_variant LOW 147C>T Phe49Phe
M0164490 NEJIMKPK_00167 168811 5 Gut 0.09 protein_coding synonymous_variant LOW 177T>C Ile59Ile
M0164491 NEJIMKPK_00171 170499 5 Gut 0.09 protein_coding missense_variant MODERATE 1478T>C Ile493Thr
M0164492 NEJIMKPK_00171 171724 5 Gut 0.09 protein_coding missense_variant MODERATE 253T>C Cys85Arg
M0164493 NEJIMKPK_00171 171838 3 Gut 0.06 protein_coding missense_variant MODERATE 139G>A Val47Ile
M0164494 NEJIMKPK_00072 75457 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -2319G>A None
M0164495 NEJIMKPK_00034 40506 3 Gut 0.06 protein_coding synonymous_variant LOW 498G>A Leu166Leu
M0164496 NEJIMKPK_00034 40614 4 Gut 0.08 protein_coding synonymous_variant LOW 606C>T Arg202Arg
M0164497 NEJIMKPK_00035 42698 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -1374G>A None
M0164498 NEJIMKPK_00039 42904 3 Gut 0.06 protein_coding synonymous_variant LOW 60C>T Ile20Ile
M0164499 NEJIMKPK_00039 43094 3 Gut 0.06 protein_coding missense_variant MODERATE 250G>A Glu84Lys
M0164500 NEJIMKPK_00039 44057 3 Gut 0.06 protein_coding missense_variant MODERATE 1213A>G Lys405Glu
M0164501 NEJIMKPK_00040 45266 5 Gut 0.09 protein_coding missense_variant MODERATE 278A>G Glu93Gly
M0164502 NEJIMKPK_00043 50203 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2489G>A None
M0164503 NEJIMKPK_00048 53638 3 Gut 0.06 protein_coding missense_variant MODERATE 1574A>C Asn525Thr
M0164504 NEJIMKPK_00049 54221 4 Gut 0.08 protein_coding missense_variant MODERATE 421G>A Ala141Thr
M0164505 NEJIMKPK_00051 56242 3 Gut 0.06 protein_coding synonymous_variant LOW 351C>T Arg117Arg
M0164506 NEJIMKPK_00051 56251 3 Gut 0.06 protein_coding synonymous_variant LOW 342T>C Thr114Thr
M0164507 NEJIMKPK_00051 56383 3 Gut 0.06 protein_coding synonymous_variant LOW 210T>G Ser70Ser
M0164508 NEJIMKPK_00051 56683 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -91A>G None
M0164509 NEJIMKPK_00051 56749 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -157A>G None
M0164510 NEJIMKPK_00051 56754 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -162C>T None
M0164511 NEJIMKPK_00051 58814 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2222A>T None
M0164512 NEJIMKPK_00051 58828 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2236C>T None
M0164513 NEJIMKPK_00057 58855 3 Gut 0.06 protein_coding missense_variant MODERATE 25G>A Gly9Ser
M0164514 NEJIMKPK_00057 58862 4 Gut 0.08 protein_coding missense_variant MODERATE 32G>A Ser11Asn
M0164515 NEJIMKPK_00057 58905 3 Gut 0.06 protein_coding synonymous_variant LOW 75C>T Gly25Gly
M0164516 NEJIMKPK_00057 58932 3 Gut 0.06 protein_coding synonymous_variant LOW 102G>A Glu34Glu
M0164517 NEJIMKPK_00057 59154 3 Gut 0.06 protein_coding synonymous_variant LOW 324A>T Gly108Gly
M0164518 NEJIMKPK_00057 59205 3 Gut 0.06 protein_coding synonymous_variant LOW 375C>T Leu125Leu
M0164519 NEJIMKPK_00057 59262 3 Gut 0.06 protein_coding synonymous_variant LOW 432A>T Ala144Ala
M0164520 NEJIMKPK_00057 59264 3 Gut 0.06 protein_coding missense_variant MODERATE 434A>G Asp145Gly
M0164521 NEJIMKPK_00057 59304 3 Gut 0.06 protein_coding synonymous_variant LOW 474A>C Gly158Gly
M0164522 NEJIMKPK_00057 59311 3 Gut 0.06 protein_coding missense_variant MODERATE 481A>G Ile161Val
M0164523 NEJIMKPK_00057 59326 3 Gut 0.06 protein_coding missense_variant MODERATE 496A>G Ile166Val
M0164524 NEJIMKPK_00057 59332 3 Gut 0.06 protein_coding missense_variant MODERATE 502A>G Ile168Val
M0164525 NEJIMKPK_00057 59475 3 Gut 0.06 protein_coding synonymous_variant LOW 645A>G Leu215Leu
M0164526 NEJIMKPK_00057 59513 3 Gut 0.06 protein_coding missense_variant MODERATE 683C>T Ala228Val
M0164527 NEJIMKPK_00057 59523 3 Gut 0.06 protein_coding synonymous_variant LOW 693C>T Ser231Ser
M0164528 NEJIMKPK_00051 59851 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -3259C>T None
M0164529 NEJIMKPK_00051 59906 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -3314G>A None
M0164530 NEJIMKPK_00058 60052 3 Gut 0.06 protein_coding synonymous_variant LOW 318T>C Tyr106Tyr
M0164531 NEJIMKPK_00058 60323 3 Gut 0.06 protein_coding missense_variant MODERATE 47C>T Ala16Val
M0164532 NEJIMKPK_00059 60439 3 Gut 0.06 protein_coding missense_variant MODERATE 271G>T Asp91Tyr
M0164533 NEJIMKPK_00059 60651 3 Gut 0.06 protein_coding missense_variant MODERATE 59G>C Gly20Ala
M0164534 NEJIMKPK_00060 61069 3 Gut 0.06 protein_coding missense_variant MODERATE 319C>T Pro107Ser
M0164535 NEJIMKPK_00061 61791 3 Gut 0.06 protein_coding missense_variant MODERATE 709G>A Ala237Thr
M0164536 NEJIMKPK_00061 62166 3 Gut 0.06 protein_coding missense_variant MODERATE 334G>A Val112Ile
M0164537 NEJIMKPK_00061 62179 3 Gut 0.06 protein_coding synonymous_variant LOW 321C>T Ala107Ala
M0164538 NEJIMKPK_00061 62203 3 Gut 0.06 protein_coding synonymous_variant LOW 297C>T Thr99Thr
M0164539 NEJIMKPK_00061 62213 3 Gut 0.06 protein_coding missense_variant MODERATE 287T>C Ile96Thr
M0164540 NEJIMKPK_00061 62215 3 Gut 0.06 protein_coding synonymous_variant LOW 285T>C Phe95Phe
M0164541 NEJIMKPK_00061 62246 3 Gut 0.06 protein_coding missense_variant MODERATE 254G>A Arg85Lys
M0164542 NEJIMKPK_00061 62263 3 Gut 0.06 protein_coding synonymous_variant LOW 237A>G Thr79Thr
M0164543 NEJIMKPK_00061 62269 3 Gut 0.06 protein_coding synonymous_variant LOW 231G>A Ala77Ala
M0164544 NEJIMKPK_00061 62272 3 Gut 0.06 protein_coding synonymous_variant LOW 228G>A Leu76Leu
M0164545 NEJIMKPK_00061 62275 3 Gut 0.06 protein_coding synonymous_variant LOW 225T>C Ile75Ile
M0164546 NEJIMKPK_00061 62317 3 Gut 0.06 protein_coding synonymous_variant LOW 183C>T Ala61Ala
M0164547 NEJIMKPK_00061 62389 3 Gut 0.06 protein_coding synonymous_variant LOW 111C>T Pro37Pro
M0164548 NEJIMKPK_00061 62476 3 Gut 0.06 protein_coding synonymous_variant LOW 24C>T His8His
M0164549 NEJIMKPK_00061 62487 3 Gut 0.06 protein_coding synonymous_variant LOW 13C>T Leu5Leu
M0164550 NEJIMKPK_00062 62601 3 Gut 0.06 protein_coding synonymous_variant LOW 648C>T Ile216Ile
M0164551 NEJIMKPK_00062 62694 3 Gut 0.06 protein_coding synonymous_variant LOW 555T>C Ser185Ser
M0164552 NEJIMKPK_00062 62742 3 Gut 0.06 protein_coding synonymous_variant LOW 507C>T Ile169Ile
M0164553 NEJIMKPK_00062 62745 3 Gut 0.06 protein_coding synonymous_variant LOW 504C>T Asn168Asn
M0164554 NEJIMKPK_00062 62754 3 Gut 0.06 protein_coding synonymous_variant LOW 495C>T Ala165Ala
M0164555 NEJIMKPK_00062 62796 3 Gut 0.06 protein_coding synonymous_variant LOW 453A>C Gly151Gly
M0164556 NEJIMKPK_00062 62817 3 Gut 0.06 protein_coding synonymous_variant LOW 432T>C Ser144Ser
M0164557 NEJIMKPK_00062 62867 3 Gut 0.06 protein_coding synonymous_variant LOW 382T>C Leu128Leu
M0164558 NEJIMKPK_00062 62889 3 Gut 0.06 protein_coding synonymous_variant LOW 360T>C Gly120Gly
M0164559 NEJIMKPK_00062 62910 3 Gut 0.06 protein_coding synonymous_variant LOW 339T>C Leu113Leu
M0164560 NEJIMKPK_00062 62964 3 Gut 0.06 protein_coding missense_variant MODERATE 285T>A Phe95Leu
M0164561 NEJIMKPK_00062 62973 3 Gut 0.06 protein_coding synonymous_variant LOW 276C>T Phe92Phe
M0164562 NEJIMKPK_00062 63006 3 Gut 0.06 protein_coding synonymous_variant LOW 243C>T Arg81Arg
M0164563 NEJIMKPK_00062 63036 3 Gut 0.06 protein_coding synonymous_variant LOW 213T>C Val71Val
M0164564 NEJIMKPK_00062 63039 3 Gut 0.06 protein_coding synonymous_variant LOW 210T>A Thr70Thr
M0164565 NEJIMKPK_00062 63112 3 Gut 0.06 protein_coding missense_variant MODERATE 137A>G Asn46Ser
M0164566 NEJIMKPK_00062 63120 3 Gut 0.06 protein_coding missense_variant MODERATE 129T>A His43Gln
M0164567 NEJIMKPK_00062 63150 3 Gut 0.06 protein_coding synonymous_variant LOW 99T>C Phe33Phe
M0164568 NEJIMKPK_00062 63156 3 Gut 0.06 protein_coding synonymous_variant LOW 93G>A Leu31Leu
M0164569 NEJIMKPK_00063 63293 3 Gut 0.06 protein_coding synonymous_variant LOW 834C>T Asn278Asn
M0164570 NEJIMKPK_00063 63356 3 Gut 0.06 protein_coding missense_variant MODERATE 771A>C Arg257Ser
M0164571 NEJIMKPK_00063 63518 3 Gut 0.06 protein_coding synonymous_variant LOW 609T>C Ile203Ile
M0164572 NEJIMKPK_00063 63521 3 Gut 0.06 protein_coding synonymous_variant LOW 606G>A Lys202Lys
M0164573 NEJIMKPK_00063 63602 3 Gut 0.06 protein_coding synonymous_variant LOW 525G>A Gly175Gly
M0164574 NEJIMKPK_00063 63625 3 Gut 0.06 protein_coding missense_variant MODERATE 502G>A Val168Ile
M0164575 NEJIMKPK_00063 63629 3 Gut 0.06 protein_coding synonymous_variant LOW 498G>A Lys166Lys
M0164576 NEJIMKPK_00063 63701 3 Gut 0.06 protein_coding synonymous_variant LOW 426G>A Gly142Gly
M0164577 NEJIMKPK_00063 63704 3 Gut 0.06 protein_coding synonymous_variant LOW 423C>A Ala141Ala
M0164578 NEJIMKPK_00063 63707 3 Gut 0.06 protein_coding synonymous_variant LOW 420A>G Leu140Leu
M0164579 NEJIMKPK_00063 63764 3 Gut 0.06 protein_coding synonymous_variant LOW 363T>C His121His
M0164580 NEJIMKPK_00063 63776 3 Gut 0.06 protein_coding synonymous_variant LOW 351T>C Asn117Asn
M0164581 NEJIMKPK_00063 63782 3 Gut 0.06 protein_coding synonymous_variant LOW 345G>A Leu115Leu
M0164582 NEJIMKPK_00063 63840 3 Gut 0.06 protein_coding missense_variant MODERATE 287C>T Thr96Ile
M0164583 NEJIMKPK_00063 63848 3 Gut 0.06 protein_coding synonymous_variant LOW 279T>C Ile93Ile
M0164584 NEJIMKPK_00063 63890 3 Gut 0.06 protein_coding synonymous_variant LOW 237A>G Gln79Gln
M0164585 NEJIMKPK_00063 63915 3 Gut 0.06 protein_coding missense_variant MODERATE 212A>G Lys71Arg
M0164586 NEJIMKPK_00063 63950 3 Gut 0.06 protein_coding synonymous_variant LOW 177A>G Gly59Gly
M0164587 NEJIMKPK_00063 63980 3 Gut 0.06 protein_coding synonymous_variant LOW 147T>C Ile49Ile
M0164588 NEJIMKPK_00063 63989 3 Gut 0.06 protein_coding synonymous_variant LOW 138G>A Leu46Leu
M0164589 NEJIMKPK_00063 63995 3 Gut 0.06 protein_coding synonymous_variant LOW 132T>C Ser44Ser
M0164590 NEJIMKPK_00063 64102 3 Gut 0.06 protein_coding missense_variant MODERATE 25A>C Asn9His
M0164591 NEJIMKPK_00063 64118 3 Gut 0.06 protein_coding synonymous_variant LOW 9C>T Thr3Thr
M0164592 NEJIMKPK_00058 64172 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -3803G>A None
M0164593 NEJIMKPK_00058 64184 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -3815T>C None
M0164594 NEJIMKPK_00058 64208 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -3839G>C None
M0164595 NEJIMKPK_00062 68188 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -4940A>T None
M0164596 NEJIMKPK_00062 68191 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -4943C>T None
M0164597 NEJIMKPK_00062 68227 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -4979A>G None
M0164598 NEJIMKPK_00067 68379 3 Gut 0.06 protein_coding synonymous_variant LOW 69T>C Ile23Ile
M0164599 NEJIMKPK_00067 68455 3 Gut 0.06 protein_coding missense_variant MODERATE 145A>G Asn49Asp
M0164600 NEJIMKPK_00067 68508 4 Gut 0.08 protein_coding synonymous_variant LOW 198G>A Leu66Leu
M0164601 NEJIMKPK_00067 68511 3 Gut 0.06 protein_coding synonymous_variant LOW 201C>T Gly67Gly
M0164602 NEJIMKPK_00067 68610 4 Gut 0.08 protein_coding synonymous_variant LOW 300T>C Gly100Gly
M0164603 NEJIMKPK_00067 68736 3 Gut 0.06 protein_coding synonymous_variant LOW 426T>C Gly142Gly
M0164604 NEJIMKPK_00067 68757 5 Gut 0.09 protein_coding synonymous_variant LOW 447C>T Arg149Arg
M0164605 NEJIMKPK_00067 68808 4 Gut 0.08 protein_coding synonymous_variant LOW 498T>C Ser166Ser
M0164606 NEJIMKPK_00067 68841 4 Gut 0.08 protein_coding synonymous_variant LOW 531C>T Ile177Ile
M0164607 NEJIMKPK_00067 68850 4 Gut 0.08 protein_coding synonymous_variant LOW 540C>T His180His
M0164608 NEJIMKPK_00067 68859 3 Gut 0.06 protein_coding synonymous_variant LOW 549A>G Lys183Lys
M0164609 NEJIMKPK_00068 69118 4 Gut 0.08 protein_coding synonymous_variant LOW 108C>T Asp36Asp
M0164610 NEJIMKPK_00068 69133 4 Gut 0.08 protein_coding synonymous_variant LOW 123C>T Pro41Pro
M0164611 NEJIMKPK_00068 69139 4 Gut 0.08 protein_coding synonymous_variant LOW 129G>A Leu43Leu
M0164612 NEJIMKPK_00068 69155 3 Gut 0.06 protein_coding missense_variant MODERATE 145G>A Val49Ile
M0164613 NEJIMKPK_00068 69181 4 Gut 0.08 protein_coding synonymous_variant LOW 171T>C Ser57Ser
M0164614 NEJIMKPK_00068 69190 4 Gut 0.08 protein_coding synonymous_variant LOW 180G>T Val60Val
M0164615 NEJIMKPK_00068 69241 3 Gut 0.06 protein_coding synonymous_variant LOW 231C>T Phe77Phe
M0164616 NEJIMKPK_00068 69246 3 Gut 0.06 protein_coding missense_variant MODERATE 236A>G Lys79Arg
M0164617 NEJIMKPK_00068 69250 4 Gut 0.08 protein_coding synonymous_variant LOW 240T>C Ala80Ala
M0164618 NEJIMKPK_00068 69253 3 Gut 0.06 protein_coding synonymous_variant LOW 243T>C Gly81Gly
M0164619 NEJIMKPK_00068 69334 4 Gut 0.08 protein_coding synonymous_variant LOW 324G>A Lys108Lys
M0164620 NEJIMKPK_00068 69343 3 Gut 0.06 protein_coding synonymous_variant LOW 333A>G Val111Val
M0164621 NEJIMKPK_00068 69373 3 Gut 0.06 protein_coding synonymous_variant LOW 363A>G Ala121Ala
M0164622 NEJIMKPK_00068 69436 3 Gut 0.06 protein_coding synonymous_variant LOW 426T>C Gly142Gly
M0164623 NEJIMKPK_00068 69463 3 Gut 0.06 protein_coding synonymous_variant LOW 453A>G Leu151Leu
M0164624 NEJIMKPK_00068 69475 3 Gut 0.06 protein_coding synonymous_variant LOW 465C>T Arg155Arg
M0164625 NEJIMKPK_00068 69500 4 Gut 0.08 protein_coding synonymous_variant LOW 490A>C Arg164Arg
M0164626 NEJIMKPK_00068 69550 4 Gut 0.08 protein_coding synonymous_variant LOW 540C>T Thr180Thr
M0164627 NEJIMKPK_00068 69586 4 Gut 0.08 protein_coding synonymous_variant LOW 576G>A Ala192Ala
M0164628 NEJIMKPK_00068 69601 4 Gut 0.08 protein_coding synonymous_variant LOW 591C>T Tyr197Tyr
M0164629 NEJIMKPK_00068 69649 4 Gut 0.08 protein_coding synonymous_variant LOW 639A>G Leu213Leu
M0164630 NEJIMKPK_00069 69661 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -16T>A None
M0164631 NEJIMKPK_00069 69672 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -5C>T None
M0164632 NEJIMKPK_00069 69717 4 Gut 0.08 protein_coding missense_variant MODERATE 41C>T Ala14Val
M0164633 NEJIMKPK_00069 69723 4 Gut 0.08 protein_coding missense_variant MODERATE 47G>A Gly16Glu
M0164634 NEJIMKPK_00069 69737 3 Gut 0.06 protein_coding missense_variant MODERATE 61C>A His21Asn
M0164635 NEJIMKPK_00069 69745 3 Gut 0.06 protein_coding synonymous_variant LOW 69G>A Ser23Ser
M0164636 NEJIMKPK_00069 69754 3 Gut 0.06 protein_coding synonymous_variant LOW 78G>A Arg26Arg
M0164637 NEJIMKPK_00069 69820 4 Gut 0.08 protein_coding synonymous_variant LOW 144T>A Gly48Gly
M0164638 NEJIMKPK_00069 69839 3 Gut 0.06 protein_coding missense_variant MODERATE 163C>T Arg55Cys
M0164639 NEJIMKPK_00069 69840 4 Gut 0.08 protein_coding missense_variant MODERATE 164G>A Arg55His
M0164640 NEJIMKPK_00069 69916 4 Gut 0.08 protein_coding synonymous_variant LOW 240C>T Asp80Asp
M0164641 NEJIMKPK_00069 69952 4 Gut 0.08 protein_coding synonymous_variant LOW 276G>A Glu92Glu
M0164642 NEJIMKPK_00069 69953 4 Gut 0.08 protein_coding synonymous_variant LOW 277T>C Leu93Leu
M0164643 NEJIMKPK_00069 69965 4 Gut 0.08 protein_coding missense_variant MODERATE 289A>G Ile97Val
M0164644 NEJIMKPK_00069 70000 4 Gut 0.08 protein_coding synonymous_variant LOW 324T>A Val108Val
M0164645 NEJIMKPK_00069 70080 3 Gut 0.06 protein_coding missense_variant MODERATE 404A>G Asn135Ser
M0164646 NEJIMKPK_00069 70081 4 Gut 0.08 protein_coding synonymous_variant LOW 405T>C Asn135Asn
M0164647 NEJIMKPK_00069 70094 3 Gut 0.06 protein_coding synonymous_variant LOW 418T>C Leu140Leu
M0164648 NEJIMKPK_00070 70375 4 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -403T>A None
M0164649 NEJIMKPK_00070 70448 4 Gut 0.08 protein_coding upstream_gene_variant MODIFIER -330C>T None
M0164650 NEJIMKPK_00071 71113 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -225T>A None
M0164651 NEJIMKPK_00071 71243 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -95A>G None
M0164652 NEJIMKPK_00071 71830 3 Gut 0.06 protein_coding missense_variant MODERATE 493G>A Ala165Thr
M0164653 NEJIMKPK_00071 71881 5 Gut 0.09 protein_coding missense_variant MODERATE 544A>G Ile182Val
M0164654 NEJIMKPK_00071 71901 5 Gut 0.09 protein_coding synonymous_variant LOW 564A>G Pro188Pro
M0164655 NEJIMKPK_00071 71958 5 Gut 0.09 protein_coding synonymous_variant LOW 621C>T Ser207Ser
M0164656 NEJIMKPK_00071 72000 4 Gut 0.08 protein_coding synonymous_variant LOW 663T>C Arg221Arg
M0164657 NEJIMKPK_00071 72015 4 Gut 0.08 protein_coding synonymous_variant LOW 678C>T Asn226Asn
M0164658 NEJIMKPK_00071 72055 4 Gut 0.08 protein_coding missense_variant MODERATE 718A>G Lys240Glu
M0164659 NEJIMKPK_00071 72078 4 Gut 0.08 protein_coding missense_variant MODERATE 741T>G Asn247Lys
M0164660 NEJIMKPK_00071 72099 4 Gut 0.08 protein_coding synonymous_variant LOW 762G>A Arg254Arg
M0164661 NEJIMKPK_00071 72105 3 Gut 0.06 protein_coding synonymous_variant LOW 768A>G Glu256Glu
M0164662 NEJIMKPK_00071 72161 3 Gut 0.06 protein_coding missense_variant MODERATE 824G>A Ser275Asn
M0164663 NEJIMKPK_00071 72215 3 Gut 0.06 protein_coding stop_lost&splice_region_variant HIGH 878A>T Ter293Leuext*?
M0164664 NEJIMKPK_00066 72228 3 Gut 0.06 protein_coding downstream_gene_variant MODIFIER *4235A>G None
M0164665 NEJIMKPK_00066 72232 3 Gut 0.06 protein_coding downstream_gene_variant MODIFIER *4239C>G None
M0164666 NEJIMKPK_00066 72256 3 Gut 0.06 protein_coding downstream_gene_variant MODIFIER *4263C>T None
M0164667 NEJIMKPK_00072 72368 3 Gut 0.06 protein_coding synonymous_variant LOW 771A>G Val257Val
M0164668 NEJIMKPK_00072 72527 3 Gut 0.06 protein_coding synonymous_variant LOW 612T>C Tyr204Tyr
M0164669 NEJIMKPK_00072 72611 3 Gut 0.06 protein_coding synonymous_variant LOW 528T>C Ser176Ser
M0164670 NEJIMKPK_00072 73073 3 Gut 0.06 protein_coding synonymous_variant LOW 66C>T His22His
M0164671 NEJIMKPK_00073 73221 3 Gut 0.06 protein_coding synonymous_variant LOW 2212T>C Leu738Leu
M0164672 NEJIMKPK_00073 73879 3 Gut 0.06 protein_coding synonymous_variant LOW 1554G>A Leu518Leu
M0164673 NEJIMKPK_00073 73945 3 Gut 0.06 protein_coding synonymous_variant LOW 1488C>T Asn496Asn
M0164674 NEJIMKPK_00073 73954 3 Gut 0.06 protein_coding synonymous_variant LOW 1479T>C Asn493Asn
M0164675 NEJIMKPK_00073 73960 3 Gut 0.06 protein_coding synonymous_variant LOW 1473C>T Tyr491Tyr
M0164676 NEJIMKPK_00073 74185 3 Gut 0.06 protein_coding synonymous_variant LOW 1248C>T Gly416Gly
M0164677 NEJIMKPK_00073 74317 3 Gut 0.06 protein_coding synonymous_variant LOW 1116T>C Ile372Ile
M0164678 NEJIMKPK_00073 74644 3 Gut 0.06 protein_coding synonymous_variant LOW 789C>T Tyr263Tyr
M0164679 NEJIMKPK_00073 74647 3 Gut 0.06 protein_coding synonymous_variant LOW 786T>A Gly262Gly
M0164680 NEJIMKPK_00073 74658 3 Gut 0.06 protein_coding synonymous_variant LOW 775C>T Leu259Leu
M0164681 NEJIMKPK_00073 74695 3 Gut 0.06 protein_coding synonymous_variant LOW 738T>C Ser246Ser
M0164682 NEJIMKPK_00073 74713 3 Gut 0.06 protein_coding synonymous_variant LOW 720C>T Ser240Ser
M0164683 NEJIMKPK_00073 74716 3 Gut 0.06 protein_coding synonymous_variant LOW 717A>G Glu239Glu
M0164684 NEJIMKPK_00073 74737 3 Gut 0.06 protein_coding synonymous_variant LOW 696C>T Asn232Asn
M0164685 NEJIMKPK_00073 74755 3 Gut 0.06 protein_coding synonymous_variant LOW 678C>T Asp226Asp
M0164686 NEJIMKPK_00073 74764 3 Gut 0.06 protein_coding synonymous_variant LOW 669A>G Glu223Glu
M0164687 NEJIMKPK_00073 74784 3 Gut 0.06 protein_coding missense_variant MODERATE 649G>A Val217Ile
M0164688 NEJIMKPK_00073 74797 3 Gut 0.06 protein_coding synonymous_variant LOW 636A>G Glu212Glu
M0164689 NEJIMKPK_00073 74809 3 Gut 0.06 protein_coding synonymous_variant LOW 624C>T Cys208Cys
M0164690 NEJIMKPK_00073 74824 3 Gut 0.06 protein_coding synonymous_variant LOW 609G>A Lys203Lys
M0164691 NEJIMKPK_00073 74834 3 Gut 0.06 protein_coding missense_variant MODERATE 599G>A Gly200Glu
M0164692 NEJIMKPK_00073 74842 3 Gut 0.06 protein_coding synonymous_variant LOW 591G>A Leu197Leu
M0164693 NEJIMKPK_00073 74857 3 Gut 0.06 protein_coding synonymous_variant LOW 576C>T Tyr192Tyr
M0164694 NEJIMKPK_00073 74860 3 Gut 0.06 protein_coding synonymous_variant LOW 573A>G Leu191Leu
M0164695 NEJIMKPK_00073 74868 3 Gut 0.06 protein_coding missense_variant MODERATE 565A>G Ile189Val
M0164696 NEJIMKPK_00073 74881 3 Gut 0.06 protein_coding synonymous_variant LOW 552A>T Gly184Gly
M0164697 NEJIMKPK_00073 74938 4 Gut 0.08 protein_coding synonymous_variant LOW 495C>T Arg165Arg
M0164698 NEJIMKPK_00073 74956 3 Gut 0.06 protein_coding synonymous_variant LOW 477C>T Ser159Ser
M0164699 NEJIMKPK_00073 74989 3 Gut 0.06 protein_coding synonymous_variant LOW 444G>A Thr148Thr
M0164700 NEJIMKPK_00073 75037 3 Gut 0.06 protein_coding synonymous_variant LOW 396C>T Phe132Phe
M0164701 NEJIMKPK_00072 75433 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2295T>C None
M0164702 NEJIMKPK_00072 75497 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2359A>T None
M0164703 NEJIMKPK_00072 75549 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2411G>T None
M0164704 NEJIMKPK_00072 75581 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2443A>C None
M0164705 NEJIMKPK_00072 75601 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2463A>G None
M0164706 NEJIMKPK_00072 75700 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2562T>C None
M0164707 NEJIMKPK_00072 75708 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2570A>G None
M0164708 NEJIMKPK_00072 75713 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2575T>A None
M0164709 NEJIMKPK_00072 75723 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2585T>C None
M0164710 NEJIMKPK_00072 75729 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2591T>C None
M0164711 NEJIMKPK_00072 75730 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2592C>T None
M0164712 NEJIMKPK_00072 75731 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -2593A>G None
M0164713 NEJIMKPK_00074 76046 3 Gut 0.06 protein_coding stop_gained HIGH 277G>T Glu93*
M0164714 NEJIMKPK_00077 79153 3 Gut 0.06 protein_coding missense_variant MODERATE 434C>T Thr145Ile
M0164715 NEJIMKPK_00079 80911 4 Gut 0.08 protein_coding synonymous_variant LOW 702C>T Ile234Ile
M0164716 NEJIMKPK_00079 81181 4 Gut 0.08 protein_coding synonymous_variant LOW 432A>G Glu144Glu
M0164717 NEJIMKPK_00079 81196 4 Gut 0.08 protein_coding synonymous_variant LOW 417C>T Asp139Asp
M0164718 NEJIMKPK_00079 81322 4 Gut 0.08 protein_coding synonymous_variant LOW 291T>C Asn97Asn
M0164719 NEJIMKPK_00079 81490 4 Gut 0.08 protein_coding synonymous_variant LOW 123G>A Gly41Gly
M0164720 NEJIMKPK_00079 81523 3 Gut 0.06 protein_coding synonymous_variant LOW 90G>A Glu30Glu
M0164721 NEJIMKPK_00079 81532 3 Gut 0.06 protein_coding synonymous_variant LOW 81A>G Ser27Ser
M0164722 NEJIMKPK_00080 82009 4 Gut 0.08 protein_coding missense_variant MODERATE 1501C>A Leu501Ile
M0164723 NEJIMKPK_00080 82106 4 Gut 0.08 protein_coding synonymous_variant LOW 1404C>T Tyr468Tyr
M0164724 NEJIMKPK_00080 82169 3 Gut 0.06 protein_coding synonymous_variant LOW 1341T>C Phe447Phe
M0164725 NEJIMKPK_00080 82232 3 Gut 0.06 protein_coding synonymous_variant LOW 1278C>T Ser426Ser
M0164726 NEJIMKPK_00080 82244 3 Gut 0.06 protein_coding synonymous_variant LOW 1266T>C Ile422Ile
M0164727 NEJIMKPK_00080 82262 3 Gut 0.06 protein_coding synonymous_variant LOW 1248G>A Lys416Lys
M0164728 NEJIMKPK_00080 82334 3 Gut 0.06 protein_coding synonymous_variant LOW 1176T>C Asn392Asn
M0164729 NEJIMKPK_00080 82363 3 Gut 0.06 protein_coding missense_variant MODERATE 1147A>G Asn383Asp
M0164730 NEJIMKPK_00080 82391 4 Gut 0.08 protein_coding synonymous_variant LOW 1119A>G Lys373Lys
M0164731 NEJIMKPK_00080 82404 4 Gut 0.08 protein_coding missense_variant MODERATE 1106G>A Arg369Lys
M0164732 NEJIMKPK_00080 82415 4 Gut 0.08 protein_coding synonymous_variant LOW 1095G>A Glu365Glu
M0164733 NEJIMKPK_00080 82421 4 Gut 0.08 protein_coding synonymous_variant LOW 1089C>T Tyr363Tyr
M0164734 NEJIMKPK_00080 82424 4 Gut 0.08 protein_coding synonymous_variant LOW 1086T>C Asp362Asp
M0164735 NEJIMKPK_00080 82475 4 Gut 0.08 protein_coding synonymous_variant LOW 1035A>G Pro345Pro
M0164736 NEJIMKPK_00080 82568 4 Gut 0.08 protein_coding synonymous_variant LOW 942A>G Leu314Leu
M0164737 NEJIMKPK_00080 82592 4 Gut 0.08 protein_coding synonymous_variant LOW 918A>G Lys306Lys
M0164738 NEJIMKPK_00080 82712 3 Gut 0.06 protein_coding synonymous_variant LOW 798A>G Glu266Glu
M0164739 NEJIMKPK_00080 83044 3 Gut 0.06 protein_coding missense_variant MODERATE 466G>A Asp156Asn
M0164740 NEJIMKPK_00080 83198 3 Gut 0.06 protein_coding synonymous_variant LOW 312G>A Lys104Lys
M0164741 NEJIMKPK_00080 83414 4 Gut 0.08 protein_coding synonymous_variant LOW 96A>G Lys32Lys
M0164742 NEJIMKPK_00077 83616 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -4030C>T None
M0164743 NEJIMKPK_00077 83890 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -4304A>G None
M0164744 NEJIMKPK_00081 83966 5 Gut 0.09 protein_coding synonymous_variant LOW 141A>G Leu47Leu
M0164745 NEJIMKPK_00077 84203 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -4617T>C None
M0164746 NEJIMKPK_00082 84226 5 Gut 0.09 protein_coding stop_lost&splice_region_variant HIGH 247T>C Ter83Glnext*?
M0164747 NEJIMKPK_00082 84287 5 Gut 0.09 protein_coding synonymous_variant LOW 186C>T His62His
M0164748 NEJIMKPK_00082 84300 5 Gut 0.09 protein_coding missense_variant MODERATE 173G>A Cys58Tyr
M0164749 NEJIMKPK_00082 84341 5 Gut 0.09 protein_coding synonymous_variant LOW 132G>A Leu44Leu
M0164750 NEJIMKPK_00082 84403 5 Gut 0.09 protein_coding missense_variant MODERATE 70C>T His24Tyr
M0164751 NEJIMKPK_00082 84461 5 Gut 0.09 protein_coding synonymous_variant LOW 12C>T Val4Val
M0164752 NEJIMKPK_00077 84478 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -4892A>G None
M0164753 NEJIMKPK_00083 84499 5 Gut 0.09 protein_coding missense_variant MODERATE 277A>G Arg93Gly
M0164754 NEJIMKPK_00083 84506 5 Gut 0.09 protein_coding missense_variant MODERATE 270G>T Gln90His
M0164755 NEJIMKPK_00083 84538 5 Gut 0.09 protein_coding missense_variant MODERATE 238G>T Val80Phe
M0164756 NEJIMKPK_00083 84575 5 Gut 0.09 protein_coding synonymous_variant LOW 201C>T Thr67Thr
M0164757 NEJIMKPK_00083 84659 5 Gut 0.09 protein_coding synonymous_variant LOW 117C>T Asn39Asn
M0164758 NEJIMKPK_00083 84662 4 Gut 0.08 protein_coding synonymous_variant LOW 114G>A Glu38Glu
M0164759 NEJIMKPK_00083 84707 5 Gut 0.09 protein_coding synonymous_variant LOW 69T>C Asn23Asn
M0164760 NEJIMKPK_00083 84755 5 Gut 0.09 protein_coding synonymous_variant LOW 21G>T Ser7Ser
M0164761 NEJIMKPK_00083 84760 5 Gut 0.09 protein_coding missense_variant MODERATE 16G>A Val6Ile
M0164762 NEJIMKPK_00083 84772 5 Gut 0.09 protein_coding missense_variant MODERATE 4A>G Lys2Glu
M0164763 NEJIMKPK_00078 84776 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -3956C>T None
M0164764 NEJIMKPK_00078 84789 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -3969A>T None
M0164765 NEJIMKPK_00078 84804 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -3984G>A None
M0164766 NEJIMKPK_00078 84807 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -3987C>A None
M0164767 NEJIMKPK_00078 84812 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -3992A>G None
M0164768 NEJIMKPK_00078 84892 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -4072T>C None
M0164769 NEJIMKPK_00078 84931 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -4111C>T None
M0164770 NEJIMKPK_00078 85042 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -4222A>T None
M0164771 NEJIMKPK_00078 85085 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -4265G>A None
M0164772 NEJIMKPK_00078 85088 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -4268A>G None
M0164773 NEJIMKPK_00078 85119 5 Gut 0.09 protein_coding upstream_gene_variant MODIFIER -4299C>T None
M0164774 NEJIMKPK_00084 86447 3 Gut 0.06 protein_coding missense_variant MODERATE 2156C>T Ala719Val
M0164775 NEJIMKPK_00084 86889 3 Gut 0.06 protein_coding missense_variant MODERATE 1714G>A Ala572Thr
M0164776 NEJIMKPK_00084 86977 4 Gut 0.08 protein_coding synonymous_variant LOW 1626C>T Ser542Ser
M0164777 NEJIMKPK_00084 88421 6 Gut 0.11 protein_coding missense_variant MODERATE 182A>G His61Arg
M0164778 NEJIMKPK_00089 92074 3 Gut 0.06 protein_coding synonymous_variant LOW 1479T>A Ala493Ala
M0164779 NEJIMKPK_00092 95981 3 Gut 0.06 protein_coding missense_variant MODERATE 970G>A Ala324Thr
M0164780 NEJIMKPK_00088 97000 3 Gut 0.06 protein_coding upstream_gene_variant MODIFIER -4958C>T None
M0164781 NEJIMKPK_00093 97218 3 Gut 0.06 protein_coding synonymous_variant LOW 66A>G Lys22Lys
M0164782 NEJIMKPK_00093 97263 4 Gut 0.08 protein_coding synonymous_variant LOW 111C>T Ser37Ser
M0164783 NEJIMKPK_00093 97272 4 Gut 0.08 protein_coding synonymous_variant LOW 120T>C Ile40Ile
M0164784 NEJIMKPK_00093 97317 4 Gut 0.08 protein_coding synonymous_variant LOW 165G>A Ala55Ala
M0164785 NEJIMKPK_00093 97326 4 Gut 0.08 protein_coding synonymous_variant LOW 174T>A Thr58Thr
M0164786 NEJIMKPK_00093 97332 4 Gut 0.08 protein_coding synonymous_variant LOW 180T>C Asp60Asp
M0164787 NEJIMKPK_00093 97402 3 Gut 0.06 protein_coding missense_variant MODERATE 250A>G Asn84Asp
M0164788 NEJIMKPK_00093 97728 3 Gut 0.06 protein_coding synonymous_variant LOW 576C>T Ser192Ser
M0164789 NEJIMKPK_00093 97740 3 Gut 0.06 protein_coding synonymous_variant LOW 588T>A Ala196Ala
M0164790 NEJIMKPK_00093 97773 3 Gut 0.06 protein_coding missense_variant MODERATE 621G>T Met207Ile
M0164791 NEJIMKPK_00093 97794 3 Gut 0.06 protein_coding synonymous_variant LOW 642T>C His214His
M0164792 NEJIMKPK_00093 98091 3 Gut 0.06 protein_coding synonymous_variant LOW 939T>C Gly313Gly
M0164793 NEJIMKPK_00101 107633 3 Gut 0.06 protein_coding missense_variant MODERATE 86A>G Glu29Gly
M0164794 NEJIMKPK_00102 113384 3 Gut 0.06 protein_coding synonymous_variant LOW 1947T>C Val649Val
M0164795 NEJIMKPK_00105 117061 3 Gut 0.06 protein_coding missense_variant MODERATE 688A>G Thr230Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
NEJIMKPK_00141 AKI05356.1|GH1 100 5.15999999999989e-311 1 407 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
NEJIMKPK_00116 2.A.21.3.20 74.7 1.6e-208 1 498 0.9940 0.9960 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.21 The Solute:Sodium Symporter (SSS) Family