Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C426
  Reference Plasmid   NZ_CP011450.1
  Reference Plasmid Size   374401
  Reference Plasmid GC Content   0.65
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0087198 AMLAAGKC_00263 255644 13 Skin 0.62 protein_coding synonymous_variant LOW 9G>A Glu3Glu
M0087199 AMLAAGKC_00264 256273 5 Skin 0.24 protein_coding synonymous_variant LOW 207T>C Gly69Gly
M0087200 AMLAAGKC_00265 256592 4 Skin 0.19 protein_coding synonymous_variant LOW 138C>T Ala46Ala
M0087201 AMLAAGKC_00265 256697 6 Skin 0.29 protein_coding synonymous_variant LOW 243C>G Ser81Ser
M0087202 AMLAAGKC_00265 256714 6 Skin 0.29 protein_coding missense_variant MODERATE 260C>T Ala87Val
M0087203 AMLAAGKC_00265 256926 5 Skin 0.24 protein_coding missense_variant MODERATE 472C>G Arg158Gly
M0087204 AMLAAGKC_00265 257189 14 Skin 0.67 protein_coding synonymous_variant LOW 735T>C His245His
M0087205 AMLAAGKC_00265 257219 10 Skin 0.48 protein_coding missense_variant MODERATE 765C>A Asp255Glu
M0087206 AMLAAGKC_00265 257513 4 Skin 0.19 protein_coding synonymous_variant LOW 1059G>A Leu353Leu
M0087207 AMLAAGKC_00265 256511 4 Skin 0.19 protein_coding synonymous_variant LOW 57G>A Ala19Ala
M0087208 AMLAAGKC_00265 257708 3 Skin 0.14 protein_coding synonymous_variant LOW 1254G>A Pro418Pro
M0087209 AMLAAGKC_00263 255667 6 Skin 0.29 protein_coding missense_variant MODERATE 32G>A Arg11His
M0087210 AMLAAGKC_00263 255732 4 Skin 0.19 protein_coding missense_variant MODERATE 97T>G Ser33Ala
M0087211 AMLAAGKC_00263 255956 4 Skin 0.19 protein_coding synonymous_variant LOW 321T>C Ser107Ser
M0087212 AMLAAGKC_00265 256506 5 Skin 0.24 protein_coding missense_variant MODERATE 52G>A Ala18Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
AMLAAGKC_00162 Copper (Cu) 100 4.7e-63 1 125 1.0000 1.0000 prediction
AMLAAGKC_00199 Mercury (Hg) 100 6.8e-83 1 159 1.0000 1.0000 prediction
AMLAAGKC_00251 Mercury (Hg) 100 4e-74 1 145 1.0000 1.0000 prediction
AMLAAGKC_00361 Arsenic (As) 75 6.8e-90 14 238 0.9268 0.9540 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
AMLAAGKC_00050 AKH18689.1|GT4 100 0 1 769 1 1
AMLAAGKC_00051 AKH18690.1|GH130 100 0 1 447 1 1
AMLAAGKC_00077 AKH18715.1|GH130 100 1.3e-297 1 403 1 0.9394
AMLAAGKC_00190 BAV66381.1|GH130 99.5 0 1 433 1 1
AMLAAGKC_00237 WCP15702.1|GT4 73.1 0 1 748 0.9421 0.9338
AMLAAGKC_00238 AKH18858.1|GH130 100 0 1 429 1 1
AMLAAGKC_00245 AKH18866.1|GH130 100 3.07999980145223e-317 1 433 1 0.9977
AMLAAGKC_00337 AKH18958.1|GH92 100 0 1 753 1 0.9974
AMLAAGKC_00338 AKH18959.1|GH105 99.7 8.36e-295 6 393 0.9873 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
AMLAAGKC_00159 3.A.3.5.39 72.1 2.19999999999998e-310 13 785 0.9847 0.9607 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.3 The P-type ATPase (P-ATPase) Superfamily