Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C427
  Reference Plasmid   NZ_CP012291.1
  Reference Plasmid Size   143870
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0164803 CHHDFJFG_00033 28399 3 Gut 1.00 protein_coding missense_variant MODERATE 401G>T Arg134Leu
M0164804 CHHDFJFG_00033 28754 3 Gut 1.00 protein_coding synonymous_variant LOW 756T>C Val252Val
M0164805 CHHDFJFG_00033 28813 3 Gut 1.00 protein_coding missense_variant MODERATE 815G>T Gly272Val
M0164806 CHHDFJFG_00033 29055 3 Gut 1.00 protein_coding missense_variant MODERATE 1057G>A Ala353Thr
M0164807 CHHDFJFG_00033 29087 3 Gut 1.00 protein_coding synonymous_variant LOW 1089G>T Ser363Ser
M0164808 CHHDFJFG_00033 29118 3 Gut 1.00 protein_coding missense_variant MODERATE 1120A>T Asn374Tyr
M0164809 CHHDFJFG_00033 29182 3 Gut 1.00 protein_coding missense_variant MODERATE 1184T>G Val395Gly
M0164810 CHHDFJFG_00036 30797 3 Gut 1.00 protein_coding synonymous_variant LOW 174G>A Pro58Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
CHHDFJFG_00013 Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Acriflavine [class: Acridine], Ethidium Bromide [class: Phenanthridine], Safranin O [class: Azin], Pyronin Y [class: Xanthene] 100 1.9e-52 1 107 1.0000 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
CHHDFJFG_00026 AMV63908.1|GH20 100 2.98e-267 1 358 1 1
CHHDFJFG_00027 AMV68251.1|GT2 100 0 1 507 1 1
CHHDFJFG_00028 AMV68252.1|CE4 100 5.44e-225 1 296 1 1
CHHDFJFG_00047 AMV68266.1|CBM34|GH13_20 100 0 1 588 1 1
CHHDFJFG_00051 QBA78937.1|GT2 96.2 2.22e-179 19 280 0.9357 0.8291
CHHDFJFG_00056 AGL62902.2|GH36 99 7.13e-223 1 309 1 1
CHHDFJFG_00061 AGL62902.2|GH36 99 8.32e-222 1 309 1 1
CHHDFJFG_00084 AGL64047.2|GH65 81.8 4.14e-233 1 390 1 1
CHHDFJFG_00089 AGL62902.2|GH36 98.6 9.71e-200 1 281 1 0.9094
CHHDFJFG_00114 AMV68266.1|CBM34|GH13_20 100 0 1 588 1 1
CHHDFJFG_00118 QBA78937.1|GT2 96.2 2.22e-179 19 280 0.9357 0.8291
CHHDFJFG_00123 AGL62902.2|GH36 99 7.13e-223 1 309 1 1
CHHDFJFG_00138 QBA78937.1|GT2 98.2 8.39e-159 19 246 0.9268 0.7215
CHHDFJFG_00142 ANK61110.1|GH65 100 0 1 750 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term