Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C443
  Reference Plasmid   NZ_CP014238.1
  Reference Plasmid Size   40342
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0087954 FLPJDAAC_00032 30589 3 Skin 0.06 protein_coding missense_variant MODERATE 2483C>A Ala828Glu
M0087955 FLPJDAAC_00032 30595 5 Skin 0.10 protein_coding missense_variant MODERATE 2477A>C Glu826Ala
M0087956 FLPJDAAC_00032 30620 5 Skin 0.10 protein_coding missense_variant MODERATE 2452A>T Thr818Ser
M0087957 FLPJDAAC_00032 30630 7 Skin 0.15 protein_coding synonymous_variant LOW 2442T>C Phe814Phe
M0087958 FLPJDAAC_00032 30636 3 Skin 0.06 protein_coding synonymous_variant LOW 2436C>T Ser812Ser
M0087959 FLPJDAAC_00032 30637 3 Skin 0.06 protein_coding missense_variant MODERATE 2435G>C Ser812Thr
M0087960 FLPJDAAC_00032 30666 6 Skin 0.13 protein_coding synonymous_variant LOW 2406G>A Gln802Gln
M0087961 FLPJDAAC_00032 30702 5 Skin 0.10 protein_coding synonymous_variant LOW 2370C>A Ser790Ser
M0087962 FLPJDAAC_00032 30705 5 Skin 0.10 protein_coding synonymous_variant LOW 2367A>G Gly789Gly
M0087963 FLPJDAAC_00032 30715 5 Skin 0.10 protein_coding missense_variant MODERATE 2357A>C His786Pro
M0087964 FLPJDAAC_00032 30716 5 Skin 0.10 protein_coding missense_variant MODERATE 2356C>G His786Asp
M0087965 FLPJDAAC_00032 30726 6 Skin 0.13 protein_coding synonymous_variant LOW 2346A>G Leu782Leu
M0087966 FLPJDAAC_00032 30741 4 Skin 0.08 protein_coding synonymous_variant LOW 2331T>C Ala777Ala
M0087967 FLPJDAAC_00032 30760 4 Skin 0.08 protein_coding missense_variant MODERATE 2312A>G Gln771Arg
M0087968 FLPJDAAC_00032 30806 4 Skin 0.08 protein_coding missense_variant MODERATE 2266A>G Asn756Asp
M0087969 FLPJDAAC_00032 30827 6 Skin 0.13 protein_coding missense_variant MODERATE 2245G>C Glu749Gln
M0087970 FLPJDAAC_00032 31077 3 Skin 0.06 protein_coding synonymous_variant LOW 1995T>G Ala665Ala
M0087971 FLPJDAAC_00032 31149 5 Skin 0.10 protein_coding synonymous_variant LOW 1923A>G Leu641Leu
M0087972 FLPJDAAC_00032 31172 3 Skin 0.06 protein_coding missense_variant MODERATE 1900G>A Ala634Thr
M0087973 FLPJDAAC_00032 31723 10 Skin 0.21 protein_coding missense_variant MODERATE 1349C>T Ser450Phe
M0087974 FLPJDAAC_00032 32856 3 Skin 0.06 protein_coding synonymous_variant LOW 216A>G Ser72Ser
M0087975 FLPJDAAC_00032 32859 8 Skin 0.17 protein_coding missense_variant MODERATE 213T>A Phe71Leu
M0087976 FLPJDAAC_00032 32874 8 Skin 0.17 protein_coding synonymous_variant LOW 198T>C Tyr66Tyr
M0087977 FLPJDAAC_00032 32949 8 Skin 0.17 protein_coding synonymous_variant LOW 123G>A Glu41Glu
M0087978 FLPJDAAC_00032 33018 8 Skin 0.17 protein_coding synonymous_variant LOW 54A>G Arg18Arg
M0087979 FLPJDAAC_00032 33052 8 Skin 0.17 protein_coding missense_variant MODERATE 20G>A Ser7Asn
M0087980 FLPJDAAC_00028 33098 7 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4697T>G None
M0087981 FLPJDAAC_00028 33110 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -4709A>C None
M0087982 FLPJDAAC_00028 33121 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -4720G>C None
M0087983 FLPJDAAC_00033 33135 4 Skin 0.08 protein_coding synonymous_variant LOW 441T>C Thr147Thr
M0087984 FLPJDAAC_00029 33743 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -3963T>C None
M0087985 FLPJDAAC_00034 34098 3 Skin 0.06 protein_coding synonymous_variant LOW 222C>T Ala74Ala
M0087986 FLPJDAAC_00034 34104 3 Skin 0.06 protein_coding synonymous_variant LOW 228G>A Leu76Leu
M0087987 FLPJDAAC_00035 34562 4 Skin 0.08 protein_coding synonymous_variant LOW 258A>G Gln86Gln
M0087988 FLPJDAAC_00035 34661 4 Skin 0.08 protein_coding synonymous_variant LOW 159G>A Glu53Glu
M0087989 FLPJDAAC_00035 34669 4 Skin 0.08 protein_coding synonymous_variant LOW 151T>C Leu51Leu
M0087990 FLPJDAAC_00035 34676 4 Skin 0.08 protein_coding synonymous_variant LOW 144G>A Ala48Ala
M0087991 FLPJDAAC_00006 4637 8 Skin 0.17 protein_coding missense_variant MODERATE 2247A>T Glu749Asp
M0087992 FLPJDAAC_00006 4666 10 Skin 0.21 protein_coding missense_variant MODERATE 2218A>G Ile740Val
M0087993 FLPJDAAC_00006 5080 10 Skin 0.21 protein_coding missense_variant MODERATE 1804T>G Ser602Ala
M0087994 FLPJDAAC_00006 5869 7 Skin 0.15 protein_coding missense_variant MODERATE 1015G>A Ala339Thr
M0087995 FLPJDAAC_00006 5877 5 Skin 0.10 protein_coding missense_variant MODERATE 1007G>T Gly336Val
M0087996 FLPJDAAC_00006 6035 10 Skin 0.21 protein_coding synonymous_variant LOW 849G>C Thr283Thr
M0087997 FLPJDAAC_00006 6430 4 Skin 0.08 protein_coding missense_variant MODERATE 454A>G Lys152Glu
M0087998 FLPJDAAC_00027 30494 4 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -3886G>A None
M0087999 FLPJDAAC_00032 30650 3 Skin 0.06 protein_coding missense_variant MODERATE 2422T>C Ser808Pro
M0088000 FLPJDAAC_00032 31673 9 Skin 0.19 protein_coding missense_variant MODERATE 1399C>A Pro467Thr
M0088001 FLPJDAAC_00032 32871 6 Skin 0.13 protein_coding synonymous_variant LOW 201G>C Thr67Thr
M0088002 FLPJDAAC_00032 32916 7 Skin 0.15 protein_coding synonymous_variant LOW 156C>T Val52Val
M0088003 FLPJDAAC_00032 32928 6 Skin 0.13 protein_coding synonymous_variant LOW 144G>A Gly48Gly
M0088004 FLPJDAAC_00032 32931 7 Skin 0.15 protein_coding synonymous_variant LOW 141C>T Tyr47Tyr
M0088005 FLPJDAAC_00032 33021 7 Skin 0.15 protein_coding synonymous_variant LOW 51A>C Thr17Thr
M0088006 FLPJDAAC_00028 33076 5 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -4675G>A None
M0088007 FLPJDAAC_00035 34667 3 Skin 0.06 protein_coding missense_variant MODERATE 153A>T Leu51Phe
M0088008 FLPJDAAC_00035 34736 3 Skin 0.06 protein_coding synonymous_variant LOW 84A>G Glu28Glu
M0088009 FLPJDAAC_00035 34816 4 Skin 0.08 protein_coding missense_variant MODERATE 4C>G His2Asp
M0088010 FLPJDAAC_00032 34856 4 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -1785C>T None
M0088011 FLPJDAAC_00036 35029 4 Skin 0.08 protein_coding synonymous_variant LOW 135A>G Leu45Leu
M0088012 FLPJDAAC_00036 35112 4 Skin 0.08 protein_coding missense_variant MODERATE 52G>A Glu18Lys
M0088013 FLPJDAAC_00036 35119 4 Skin 0.08 protein_coding synonymous_variant LOW 45T>C Asp15Asp
M0088014 FLPJDAAC_00036 35122 4 Skin 0.08 protein_coding synonymous_variant LOW 42C>T Leu14Leu
M0088015 FLPJDAAC_00036 35130 4 Skin 0.08 protein_coding missense_variant MODERATE 34A>G Asn12Asp
M0088016 FLPJDAAC_00036 35136 3 Skin 0.06 protein_coding missense_variant MODERATE 28A>C Ile10Leu
M0088017 FLPJDAAC_00036 35137 4 Skin 0.08 protein_coding missense_variant MODERATE 27A>C Gln9His
M0088018 FLPJDAAC_00032 35226 4 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2155G>A None
M0088019 FLPJDAAC_00032 30570 3 Skin 0.06 protein_coding synonymous_variant LOW 2502T>C Ser834Ser
M0088020 FLPJDAAC_00032 30573 3 Skin 0.06 protein_coding synonymous_variant LOW 2499A>T Pro833Pro
M0088021 FLPJDAAC_00032 32844 4 Skin 0.08 protein_coding missense_variant MODERATE 228A>T Glu76Asp
M0088022 FLPJDAAC_00032 32961 6 Skin 0.13 protein_coding synonymous_variant LOW 111C>T Thr37Thr
M0088023 FLPJDAAC_00032 34851 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -1780T>C None
M0088024 FLPJDAAC_00036 34915 3 Skin 0.06 protein_coding synonymous_variant LOW 249G>A Glu83Glu
M0088025 FLPJDAAC_00032 35615 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -2544A>G None
M0088026 FLPJDAAC_00032 31409 3 Skin 0.06 protein_coding missense_variant MODERATE 1663C>T Pro555Ser
M0088027 FLPJDAAC_00032 31414 3 Skin 0.06 protein_coding missense_variant MODERATE 1658T>C Leu553Ser
M0088028 FLPJDAAC_00006 5630 3 Skin 0.06 protein_coding synonymous_variant LOW 1254G>A Leu418Leu
M0088029 FLPJDAAC_00006 5699 3 Skin 0.06 protein_coding synonymous_variant LOW 1185A>C Thr395Thr
M0088030 FLPJDAAC_00006 5711 3 Skin 0.06 protein_coding synonymous_variant LOW 1173T>C Arg391Arg
M0088031 FLPJDAAC_00006 6754 5 Skin 0.10 protein_coding missense_variant MODERATE 130T>G Ser44Ala
M0088032 FLPJDAAC_00006 6817 5 Skin 0.10 protein_coding missense_variant MODERATE 67A>G Ser23Gly
M0088033 FLPJDAAC_00002 1321 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -288A>T None
M0088034 FLPJDAAC_00002 1343 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -266T>A None
M0088035 FLPJDAAC_00002 1349 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -260T>G None
M0088036 FLPJDAAC_00002 1386 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -223C>T None
M0088037 FLPJDAAC_00002 1422 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -187G>A None
M0088038 FLPJDAAC_00002 1449 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -160G>T None
M0088039 FLPJDAAC_00002 1460 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -149C>A None
M0088040 FLPJDAAC_00002 1473 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -136A>G None
M0088041 FLPJDAAC_00002 1521 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -88T>C None
M0088042 FLPJDAAC_00002 1539 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -70C>T None
M0088043 FLPJDAAC_00002 1542 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -67G>A None
M0088044 FLPJDAAC_00002 1572 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -37G>T None
M0088045 FLPJDAAC_00002 1573 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -36T>C None
M0088046 FLPJDAAC_00002 1648 3 Skin 0.06 protein_coding missense_variant MODERATE 40G>A Ala14Thr
M0088047 FLPJDAAC_00002 1689 3 Skin 0.06 protein_coding missense_variant MODERATE 81T>A Asn27Lys
M0088048 FLPJDAAC_00002 1691 3 Skin 0.06 protein_coding missense_variant MODERATE 83G>A Gly28Asp
M0088049 FLPJDAAC_00002 1692 3 Skin 0.06 protein_coding synonymous_variant LOW 84C>G Gly28Gly
M0088050 FLPJDAAC_00002 1706 3 Skin 0.06 protein_coding missense_variant MODERATE 98T>C Val33Ala
M0088051 FLPJDAAC_00002 1710 3 Skin 0.06 protein_coding synonymous_variant LOW 102A>T Ile34Ile
M0088052 FLPJDAAC_00002 1713 3 Skin 0.06 protein_coding synonymous_variant LOW 105T>C Asn35Asn
M0088053 FLPJDAAC_00002 1719 3 Skin 0.06 protein_coding synonymous_variant LOW 111A>G Pro37Pro
M0088054 FLPJDAAC_00002 1728 3 Skin 0.06 protein_coding synonymous_variant LOW 120T>C Thr40Thr
M0088055 FLPJDAAC_00002 1744 3 Skin 0.06 protein_coding synonymous_variant LOW 136C>A Arg46Arg
M0088056 FLPJDAAC_00002 1749 3 Skin 0.06 protein_coding synonymous_variant LOW 141G>T Ala47Ala
M0088057 FLPJDAAC_00002 1753 3 Skin 0.06 protein_coding synonymous_variant LOW 145T>C Leu49Leu
M0088058 FLPJDAAC_00002 1767 3 Skin 0.06 protein_coding synonymous_variant LOW 159G>C Ala53Ala
M0088059 FLPJDAAC_00002 1770 3 Skin 0.06 protein_coding synonymous_variant LOW 162G>T Ala54Ala
M0088060 FLPJDAAC_00002 1776 3 Skin 0.06 protein_coding synonymous_variant LOW 168C>T Ala56Ala
M0088061 FLPJDAAC_00002 1788 3 Skin 0.06 protein_coding synonymous_variant LOW 180G>C Arg60Arg
M0088062 FLPJDAAC_00002 1813 3 Skin 0.06 protein_coding missense_variant MODERATE 205A>G Lys69Glu
M0088063 FLPJDAAC_00003 2198 3 Skin 0.06 protein_coding missense_variant MODERATE 184C>T Pro62Ser
M0088064 FLPJDAAC_00003 2245 3 Skin 0.06 protein_coding synonymous_variant LOW 231C>T Ile77Ile
M0088065 FLPJDAAC_00003 2253 3 Skin 0.06 protein_coding missense_variant MODERATE 239T>G Val80Gly
M0088066 FLPJDAAC_00004 2374 3 Skin 0.06 protein_coding missense_variant MODERATE 16G>A Ala6Thr
M0088067 FLPJDAAC_00004 2454 3 Skin 0.06 protein_coding synonymous_variant LOW 96C>G Thr32Thr
M0088068 FLPJDAAC_00004 2552 3 Skin 0.06 protein_coding missense_variant MODERATE 194C>T Ala65Val
M0088069 FLPJDAAC_00004 2565 3 Skin 0.06 protein_coding missense_variant MODERATE 207A>G Ile69Met
M0088070 FLPJDAAC_00004 2586 3 Skin 0.06 protein_coding synonymous_variant LOW 228A>G Gln76Gln
M0088071 FLPJDAAC_00004 2682 3 Skin 0.06 protein_coding missense_variant MODERATE 324T>G Asn108Lys
M0088072 FLPJDAAC_00004 2801 3 Skin 0.06 protein_coding missense_variant MODERATE 443T>A Val148Asp
M0088073 FLPJDAAC_00004 2812 3 Skin 0.06 protein_coding missense_variant MODERATE 454A>G Asn152Asp
M0088074 FLPJDAAC_00004 2826 3 Skin 0.06 protein_coding synonymous_variant LOW 468C>A Val156Val
M0088075 FLPJDAAC_00004 2841 3 Skin 0.06 protein_coding synonymous_variant LOW 483G>A Ala161Ala
M0088076 FLPJDAAC_00004 2939 3 Skin 0.06 protein_coding missense_variant MODERATE 581C>T Ala194Val
M0088077 FLPJDAAC_00004 2973 3 Skin 0.06 protein_coding synonymous_variant LOW 615A>G Ser205Ser
M0088078 FLPJDAAC_00004 2979 3 Skin 0.06 protein_coding synonymous_variant LOW 621A>G Gly207Gly
M0088079 FLPJDAAC_00004 2994 3 Skin 0.06 protein_coding synonymous_variant LOW 636G>T Ser212Ser
M0088080 FLPJDAAC_00004 3012 3 Skin 0.06 protein_coding synonymous_variant LOW 654T>C Gly218Gly
M0088081 FLPJDAAC_00004 3057 3 Skin 0.06 protein_coding synonymous_variant LOW 699G>A Arg233Arg
M0088082 FLPJDAAC_00004 3066 3 Skin 0.06 protein_coding synonymous_variant LOW 708T>C Asn236Asn
M0088083 FLPJDAAC_00007 3351 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -4051T>C None
M0088084 FLPJDAAC_00005 3423 3 Skin 0.06 protein_coding synonymous_variant LOW 535C>T Leu179Leu
M0088085 FLPJDAAC_00005 3541 3 Skin 0.06 protein_coding synonymous_variant LOW 417A>G Pro139Pro
M0088086 FLPJDAAC_00005 3544 3 Skin 0.06 protein_coding synonymous_variant LOW 414G>C Val138Val
M0088087 FLPJDAAC_00005 4506 5 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -549G>A None
M0088088 FLPJDAAC_00006 4521 5 Skin 0.10 protein_coding missense_variant MODERATE 2363G>A Arg788Lys
M0088089 FLPJDAAC_00006 4526 5 Skin 0.10 protein_coding synonymous_variant LOW 2358A>G Arg786Arg
M0088090 FLPJDAAC_00006 5648 4 Skin 0.08 protein_coding missense_variant MODERATE 1236G>A Met412Ile
M0088091 FLPJDAAC_00005 6932 4 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2975C>A None
M0088092 FLPJDAAC_00032 31332 3 Skin 0.06 protein_coding missense_variant MODERATE 1740A>C Lys580Asn






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
FLPJDAAC_00015 PHI:3165 hopA1 74.2 1.2e-24 1 66 0.8684 0.9010 eudicots leaf spot (celery); leaf spot (eggplant); leaf spot (sweet pepper); wilt rot (muskmelon); stem rot (muskmelon); stem rot (chrysanthemum); leaf spot (soybean) effector (plant avirulence determinant) effector (plant avirulence determinant)






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term