Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C444
  Reference Plasmid   NZ_CP014570.1
  Reference Plasmid Size   27417
  Reference Plasmid GC Content   0.27
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0164994 OEDAFLCN_00011 8805 3 Gut 0.60 protein_coding synonymous_variant LOW 120A>G Ala40Ala
M0164995 OEDAFLCN_00011 8977 3 Gut 0.60 protein_coding missense_variant MODERATE 292C>T His98Tyr
M0164996 OEDAFLCN_00021 16219 3 Gut 0.60 protein_coding synonymous_variant LOW 319T>C Leu107Leu
M0164997 OEDAFLCN_00021 16227 3 Gut 0.60 protein_coding synonymous_variant LOW 327C>A Gly109Gly
M0164998 OEDAFLCN_00021 16230 3 Gut 0.60 protein_coding synonymous_variant LOW 330G>A Ser110Ser
M0164999 OEDAFLCN_00021 16242 3 Gut 0.60 protein_coding synonymous_variant LOW 342A>G Ala114Ala
M0165000 OEDAFLCN_00021 16269 3 Gut 0.60 protein_coding synonymous_variant LOW 369G>A Gly123Gly
M0165001 OEDAFLCN_00021 16278 3 Gut 0.60 protein_coding synonymous_variant LOW 378T>C Asn126Asn
M0165002 OEDAFLCN_00021 16281 3 Gut 0.60 protein_coding synonymous_variant LOW 381T>C Asn127Asn
M0165003 OEDAFLCN_00021 16290 3 Gut 0.60 protein_coding synonymous_variant LOW 390C>T Gly130Gly
M0165004 OEDAFLCN_00021 16302 3 Gut 0.60 protein_coding synonymous_variant LOW 402C>T Gly134Gly
M0165005 OEDAFLCN_00021 16305 3 Gut 0.60 protein_coding synonymous_variant LOW 405G>A Gly135Gly
M0165006 OEDAFLCN_00021 16317 3 Gut 0.60 protein_coding synonymous_variant LOW 417G>A Lys139Lys
M0165007 OEDAFLCN_00021 16333 3 Gut 0.60 protein_coding synonymous_variant LOW 433T>C Leu145Leu
M0165008 OEDAFLCN_00021 16338 3 Gut 0.60 protein_coding synonymous_variant LOW 438G>A Lys146Lys
M0165009 OEDAFLCN_00021 16344 3 Gut 0.60 protein_coding synonymous_variant LOW 444T>C Asn148Asn
M0165010 OEDAFLCN_00021 16359 3 Gut 0.60 protein_coding synonymous_variant LOW 459T>C Ile153Ile
M0165011 OEDAFLCN_00021 16374 3 Gut 0.60 protein_coding synonymous_variant LOW 474A>T Pro158Pro
M0165012 OEDAFLCN_00021 16383 3 Gut 0.60 protein_coding synonymous_variant LOW 483T>C Ser161Ser
M0165013 OEDAFLCN_00021 16392 3 Gut 0.60 protein_coding synonymous_variant LOW 492T>C Gly164Gly
M0165014 OEDAFLCN_00021 16407 3 Gut 0.60 protein_coding synonymous_variant LOW 507G>A Leu169Leu
M0165015 OEDAFLCN_00021 16428 3 Gut 0.60 protein_coding synonymous_variant LOW 528A>G Lys176Lys
M0165016 OEDAFLCN_00021 16440 3 Gut 0.60 protein_coding synonymous_variant LOW 540C>T Leu180Leu
M0165017 OEDAFLCN_00021 16449 3 Gut 0.60 protein_coding synonymous_variant LOW 549C>T Asp183Asp
M0165018 OEDAFLCN_00021 16455 3 Gut 0.60 protein_coding synonymous_variant LOW 555A>G Lys185Lys
M0165019 OEDAFLCN_00021 16458 3 Gut 0.60 protein_coding synonymous_variant LOW 558T>C Gly186Gly
M0165020 OEDAFLCN_00021 16764 3 Gut 0.60 protein_coding synonymous_variant LOW 864A>T Pro288Pro
M0165021 OEDAFLCN_00021 16766 3 Gut 0.60 protein_coding missense_variant MODERATE 866A>G Asn289Ser
M0165022 OEDAFLCN_00021 16771 3 Gut 0.60 protein_coding missense_variant MODERATE 871C>T His291Tyr
M0165023 OEDAFLCN_00024 19402 4 Gut 0.80 protein_coding missense_variant MODERATE 616A>G Thr206Ala
M0165024 OEDAFLCN_00027 20640 4 Gut 0.80 protein_coding synonymous_variant LOW 663T>C His221His
M0165025 OEDAFLCN_00027 20840 4 Gut 0.80 protein_coding missense_variant MODERATE 463A>G Asn155Asp
M0165026 OEDAFLCN_00030 22734 4 Gut 0.80 protein_coding synonymous_variant LOW 117A>G Lys39Lys
M0165027 OEDAFLCN_00027 23602 4 Gut 0.80 protein_coding upstream_gene_variant MODIFIER -2300A>G None
M0165028 OEDAFLCN_00005 3043 3 Gut 0.60 protein_coding synonymous_variant LOW 204T>C Ser68Ser
M0165029 OEDAFLCN_00005 3049 3 Gut 0.60 protein_coding synonymous_variant LOW 210G>A Pro70Pro
M0165030 OEDAFLCN_00005 3052 3 Gut 0.60 protein_coding synonymous_variant LOW 213T>A Leu71Leu
M0165031 OEDAFLCN_00005 3091 3 Gut 0.60 protein_coding synonymous_variant LOW 252T>C Asn84Asn
M0165032 OEDAFLCN_00005 3100 3 Gut 0.60 protein_coding synonymous_variant LOW 261G>A Val87Val
M0165033 OEDAFLCN_00005 3103 3 Gut 0.60 protein_coding synonymous_variant LOW 264A>G Ala88Ala
M0165034 OEDAFLCN_00005 3109 3 Gut 0.60 protein_coding synonymous_variant LOW 270T>A Ser90Ser
M0165035 OEDAFLCN_00005 3112 3 Gut 0.60 protein_coding synonymous_variant LOW 273G>T Thr91Thr
M0165036 OEDAFLCN_00006 3131 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -2T>A None
M0165037 OEDAFLCN_00006 3171 3 Gut 0.60 protein_coding synonymous_variant LOW 39T>C Ala13Ala
M0165038 OEDAFLCN_00006 3174 3 Gut 0.60 protein_coding synonymous_variant LOW 42T>C Phe14Phe
M0165039 OEDAFLCN_00006 3177 3 Gut 0.60 protein_coding synonymous_variant LOW 45T>C Pro15Pro
M0165040 OEDAFLCN_00006 3208 3 Gut 0.60 protein_coding missense_variant MODERATE 76A>G Asn26Asp
M0165041 OEDAFLCN_00006 3267 3 Gut 0.60 protein_coding synonymous_variant LOW 135T>G Gly45Gly
M0165042 OEDAFLCN_00006 3310 3 Gut 0.60 protein_coding missense_variant MODERATE 178G>T Ala60Ser
M0165043 OEDAFLCN_00006 3330 3 Gut 0.60 protein_coding synonymous_variant LOW 198C>T Leu66Leu
M0165044 OEDAFLCN_00006 3363 3 Gut 0.60 protein_coding synonymous_variant LOW 231T>A Ile77Ile
M0165045 OEDAFLCN_00006 3396 3 Gut 0.60 protein_coding synonymous_variant LOW 264A>C Ile88Ile
M0165046 OEDAFLCN_00006 3399 3 Gut 0.60 protein_coding synonymous_variant LOW 267C>T Asp89Asp
M0165047 OEDAFLCN_00006 3420 3 Gut 0.60 protein_coding synonymous_variant LOW 288T>C Asn96Asn
M0165048 OEDAFLCN_00006 3444 3 Gut 0.60 protein_coding synonymous_variant LOW 312T>C Asn104Asn
M0165049 OEDAFLCN_00006 3453 3 Gut 0.60 protein_coding synonymous_variant LOW 321A>G Lys107Lys
M0165050 OEDAFLCN_00006 3498 3 Gut 0.60 protein_coding synonymous_variant LOW 366T>A Ile122Ile
M0165051 OEDAFLCN_00006 3516 3 Gut 0.60 protein_coding synonymous_variant LOW 384A>G Pro128Pro
M0165052 OEDAFLCN_00006 3525 3 Gut 0.60 protein_coding synonymous_variant LOW 393G>A Lys131Lys
M0165053 OEDAFLCN_00006 3568 3 Gut 0.60 protein_coding missense_variant MODERATE 436A>G Ile146Val
M0165054 OEDAFLCN_00006 3570 3 Gut 0.60 protein_coding synonymous_variant LOW 438A>T Ile146Ile
M0165055 OEDAFLCN_00006 3662 3 Gut 0.60 protein_coding missense_variant MODERATE 530G>A Arg177Lys
M0165056 OEDAFLCN_00006 3751 3 Gut 0.60 protein_coding missense_variant MODERATE 619G>A Asp207Asn
M0165057 OEDAFLCN_00006 3768 3 Gut 0.60 protein_coding missense_variant MODERATE 636G>A Met212Ile
M0165058 OEDAFLCN_00006 4572 3 Gut 0.60 protein_coding synonymous_variant LOW 1440A>G Lys480Lys
M0165059 OEDAFLCN_00006 4579 3 Gut 0.60 protein_coding missense_variant MODERATE 1447G>A Gly483Ser
M0165060 OEDAFLCN_00006 4580 3 Gut 0.60 protein_coding missense_variant MODERATE 1448G>A Gly483Asp
M0165061 OEDAFLCN_00006 4582 3 Gut 0.60 protein_coding missense_variant MODERATE 1450G>T Ala484Ser
M0165062 OEDAFLCN_00006 4587 3 Gut 0.60 protein_coding synonymous_variant LOW 1455G>A Lys485Lys
M0165063 OEDAFLCN_00006 4614 3 Gut 0.60 protein_coding synonymous_variant LOW 1482C>T Ser494Ser
M0165064 OEDAFLCN_00006 4623 3 Gut 0.60 protein_coding synonymous_variant LOW 1491T>A Ala497Ala
M0165065 OEDAFLCN_00006 4626 3 Gut 0.60 protein_coding synonymous_variant LOW 1494T>A Pro498Pro
M0165066 OEDAFLCN_00006 4650 3 Gut 0.60 protein_coding synonymous_variant LOW 1518C>T His506His
M0165067 OEDAFLCN_00006 4656 3 Gut 0.60 protein_coding synonymous_variant LOW 1524C>T Asp508Asp
M0165068 OEDAFLCN_00006 4659 3 Gut 0.60 protein_coding synonymous_variant LOW 1527T>A Ile509Ile
M0165069 OEDAFLCN_00006 4668 3 Gut 0.60 protein_coding missense_variant MODERATE 1536T>A Asp512Glu
M0165070 OEDAFLCN_00008 6864 3 Gut 0.60 protein_coding synonymous_variant LOW 589C>T Leu197Leu
M0165071 OEDAFLCN_00008 6869 3 Gut 0.60 protein_coding synonymous_variant LOW 594G>A Lys198Lys
M0165072 OEDAFLCN_00008 6884 3 Gut 0.60 protein_coding synonymous_variant LOW 609C>T Asn203Asn
M0165073 OEDAFLCN_00008 6923 3 Gut 0.60 protein_coding synonymous_variant LOW 648C>T Asp216Asp
M0165074 OEDAFLCN_00008 6956 3 Gut 0.60 protein_coding synonymous_variant LOW 681G>A Lys227Lys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
OEDAFLCN_00016 AGJ76588.1|GH23 92 1.79e-119 1 187 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term