Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C447
  Reference Plasmid   NZ_CP015523.1
  Reference Plasmid Size   177851
  Reference Plasmid GC Content   0.65
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0088093 MIGELBLI_00022 17025 7 Skin 0.14 protein_coding missense_variant MODERATE 199G>A Ala67Thr
M0088094 MIGELBLI_00022 17078 7 Skin 0.14 protein_coding missense_variant MODERATE 146G>C Ser49Thr
M0088095 MIGELBLI_00025 20452 15 Skin 0.29 protein_coding synonymous_variant LOW 1926A>G Ser642Ser
M0088096 MIGELBLI_00130 99447 4 Skin 0.08 protein_coding synonymous_variant LOW 426A>C Ala142Ala
M0088097 MIGELBLI_00180 150942 3 Skin 0.06 protein_coding synonymous_variant LOW 108G>C Arg36Arg
M0088098 MIGELBLI_00180 151038 4 Skin 0.08 protein_coding synonymous_variant LOW 12T>C Ala4Ala
M0088099 MIGELBLI_00180 151046 4 Skin 0.08 protein_coding missense_variant MODERATE 4A>G Thr2Ala
M0088100 MIGELBLI_00181 151919 4 Skin 0.08 protein_coding missense_variant MODERATE 803A>C Lys268Thr
M0088101 MIGELBLI_00183 153086 3 Skin 0.06 protein_coding synonymous_variant LOW 165G>A Arg55Arg
M0088102 MIGELBLI_00183 153149 3 Skin 0.06 protein_coding synonymous_variant LOW 228T>C Gly76Gly
M0088103 MIGELBLI_00183 153284 3 Skin 0.06 protein_coding missense_variant MODERATE 363T>G Asp121Glu
M0088104 MIGELBLI_00183 153911 3 Skin 0.06 protein_coding synonymous_variant LOW 990A>G Leu330Leu
M0088105 MIGELBLI_00183 154040 3 Skin 0.06 protein_coding synonymous_variant LOW 1119T>C Ile373Ile
M0088106 MIGELBLI_00185 155901 3 Skin 0.06 protein_coding missense_variant MODERATE 1159G>C Glu387Gln
M0088107 MIGELBLI_00180 155957 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -4908A>C None
M0088108 MIGELBLI_00186 155978 3 Skin 0.06 protein_coding synonymous_variant LOW 9T>G Gly3Gly
M0088109 MIGELBLI_00186 156119 3 Skin 0.06 protein_coding synonymous_variant LOW 150T>G Leu50Leu
M0088110 MIGELBLI_00186 156684 3 Skin 0.06 protein_coding missense_variant MODERATE 715C>G Pro239Ala
M0088111 MIGELBLI_00186 156723 3 Skin 0.06 protein_coding missense_variant MODERATE 754G>A Gly252Ser
M0088112 MIGELBLI_00186 156839 3 Skin 0.06 protein_coding synonymous_variant LOW 870C>T Ser290Ser
M0088113 MIGELBLI_00186 157036 3 Skin 0.06 protein_coding missense_variant MODERATE 1067T>C Val356Ala
M0088114 MIGELBLI_00187 157641 3 Skin 0.06 protein_coding synonymous_variant LOW 120T>C Ala40Ala
M0088115 MIGELBLI_00187 157806 3 Skin 0.06 protein_coding synonymous_variant LOW 285A>G Glu95Glu
M0088116 MIGELBLI_00187 157875 3 Skin 0.06 protein_coding synonymous_variant LOW 354G>A Leu118Leu
M0088117 MIGELBLI_00181 150359 3 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -758T>C None
M0088118 MIGELBLI_00180 150489 3 Skin 0.06 protein_coding synonymous_variant LOW 561A>G Leu187Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
MIGELBLI_00061 Copper (Cu) 82 2.1e-47 1 122 1.0000 1.0000 prediction
MIGELBLI_00062 Copper (Cu) 76.5 1.5e-120 1 294 1.0000 0.9545 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term