Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C452
  Reference Plasmid   NZ_CP016462.1
  Reference Plasmid Size   186489
  Reference Plasmid GC Content   0.60
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0088173 LFNBLCAP_00141 147596 3 Skin 0.12 protein_coding synonymous_variant LOW 1581T>G Ala527Ala
M0088174 LFNBLCAP_00141 147620 3 Skin 0.12 protein_coding synonymous_variant LOW 1557G>A Gly519Gly
M0088175 LFNBLCAP_00141 147692 3 Skin 0.12 protein_coding synonymous_variant LOW 1485T>C Arg495Arg
M0088176 LFNBLCAP_00141 147695 3 Skin 0.12 protein_coding synonymous_variant LOW 1482G>C Ala494Ala
M0088177 LFNBLCAP_00141 147707 3 Skin 0.12 protein_coding synonymous_variant LOW 1470C>T Gly490Gly
M0088178 LFNBLCAP_00141 147719 3 Skin 0.12 protein_coding synonymous_variant LOW 1458T>G Ala486Ala
M0088179 LFNBLCAP_00141 147764 3 Skin 0.12 protein_coding synonymous_variant LOW 1413G>C Thr471Thr
M0088180 LFNBLCAP_00141 147776 3 Skin 0.12 protein_coding synonymous_variant LOW 1401C>A Arg467Arg
M0088181 LFNBLCAP_00141 147780 3 Skin 0.12 protein_coding missense_variant MODERATE 1397G>C Ser466Thr
M0088182 LFNBLCAP_00141 147782 3 Skin 0.12 protein_coding synonymous_variant LOW 1395A>G Arg465Arg
M0088183 LFNBLCAP_00141 147851 3 Skin 0.12 protein_coding synonymous_variant LOW 1326A>G Leu442Leu
M0088184 LFNBLCAP_00141 147869 3 Skin 0.12 protein_coding synonymous_variant LOW 1308C>T Thr436Thr
M0088185 LFNBLCAP_00141 147945 3 Skin 0.12 protein_coding missense_variant MODERATE 1232A>C His411Pro
M0088186 LFNBLCAP_00141 148028 3 Skin 0.12 protein_coding synonymous_variant LOW 1149G>A Ser383Ser
M0088187 LFNBLCAP_00141 148055 3 Skin 0.12 protein_coding synonymous_variant LOW 1122G>A Glu374Glu
M0088188 LFNBLCAP_00141 148112 3 Skin 0.12 protein_coding synonymous_variant LOW 1065G>C Gly355Gly
M0088189 LFNBLCAP_00141 148142 3 Skin 0.12 protein_coding synonymous_variant LOW 1035G>A Lys345Lys
M0088190 LFNBLCAP_00141 148154 3 Skin 0.12 protein_coding synonymous_variant LOW 1023A>G Glu341Glu
M0088191 LFNBLCAP_00141 148165 3 Skin 0.12 protein_coding synonymous_variant LOW 1012T>C Leu338Leu
M0088192 LFNBLCAP_00141 148172 3 Skin 0.12 protein_coding synonymous_variant LOW 1005G>A Ala335Ala
M0088193 LFNBLCAP_00141 148187 3 Skin 0.12 protein_coding synonymous_variant LOW 990T>C Phe330Phe
M0088194 LFNBLCAP_00141 148205 3 Skin 0.12 protein_coding synonymous_variant LOW 972C>T His324His
M0088195 LFNBLCAP_00141 148208 3 Skin 0.12 protein_coding synonymous_variant LOW 969G>C Gly323Gly
M0088196 LFNBLCAP_00141 148211 3 Skin 0.12 protein_coding synonymous_variant LOW 966T>C Ser322Ser
M0088197 LFNBLCAP_00141 148214 3 Skin 0.12 protein_coding synonymous_variant LOW 963G>C Pro321Pro
M0088198 LFNBLCAP_00141 148232 3 Skin 0.12 protein_coding synonymous_variant LOW 945C>T Ala315Ala
M0088199 LFNBLCAP_00141 148412 3 Skin 0.12 protein_coding synonymous_variant LOW 765A>G Lys255Lys
M0088200 LFNBLCAP_00141 148415 3 Skin 0.12 protein_coding synonymous_variant LOW 762C>G Leu254Leu
M0088201 LFNBLCAP_00141 148442 3 Skin 0.12 protein_coding synonymous_variant LOW 735C>T Thr245Thr
M0088202 LFNBLCAP_00141 148523 3 Skin 0.12 protein_coding synonymous_variant LOW 654A>G Ala218Ala
M0088203 LFNBLCAP_00141 148529 3 Skin 0.12 protein_coding synonymous_variant LOW 648C>T Val216Val
M0088204 LFNBLCAP_00141 148571 3 Skin 0.12 protein_coding synonymous_variant LOW 606A>G Val202Val
M0088205 LFNBLCAP_00141 148574 3 Skin 0.12 protein_coding synonymous_variant LOW 603G>A Ala201Ala
M0088206 LFNBLCAP_00141 148576 3 Skin 0.12 protein_coding missense_variant MODERATE 601G>C Ala201Pro
M0088207 LFNBLCAP_00141 148581 3 Skin 0.12 protein_coding missense_variant MODERATE 596G>C Arg199Thr
M0088208 LFNBLCAP_00141 148603 3 Skin 0.12 protein_coding missense_variant MODERATE 574G>A Val192Ile
M0088209 LFNBLCAP_00141 148652 3 Skin 0.12 protein_coding synonymous_variant LOW 525G>A Thr175Thr
M0088210 LFNBLCAP_00141 148667 3 Skin 0.12 protein_coding synonymous_variant LOW 510C>G Gly170Gly
M0088211 LFNBLCAP_00141 148670 3 Skin 0.12 protein_coding synonymous_variant LOW 507C>G Arg169Arg
M0088212 LFNBLCAP_00141 148688 3 Skin 0.12 protein_coding synonymous_variant LOW 489C>G Leu163Leu
M0088213 LFNBLCAP_00141 148700 3 Skin 0.12 protein_coding synonymous_variant LOW 477G>C Gly159Gly
M0088214 LFNBLCAP_00141 148730 3 Skin 0.12 protein_coding synonymous_variant LOW 447T>C Val149Val
M0088215 LFNBLCAP_00141 148742 3 Skin 0.12 protein_coding synonymous_variant LOW 435G>C Val145Val
M0088216 LFNBLCAP_00141 148748 3 Skin 0.12 protein_coding synonymous_variant LOW 429T>C Ile143Ile
M0088217 LFNBLCAP_00141 148757 3 Skin 0.12 protein_coding synonymous_variant LOW 420T>A Ala140Ala
M0088218 LFNBLCAP_00141 148841 3 Skin 0.12 protein_coding synonymous_variant LOW 336G>C Thr112Thr
M0088219 LFNBLCAP_00141 148880 3 Skin 0.12 protein_coding synonymous_variant LOW 297G>A Val99Val
M0088220 LFNBLCAP_00141 148892 3 Skin 0.12 protein_coding synonymous_variant LOW 285C>G Pro95Pro
M0088221 LFNBLCAP_00141 148910 3 Skin 0.12 protein_coding synonymous_variant LOW 267A>C Gly89Gly
M0088222 LFNBLCAP_00141 148919 3 Skin 0.12 protein_coding synonymous_variant LOW 258A>G Glu86Glu
M0088223 LFNBLCAP_00141 148937 3 Skin 0.12 protein_coding synonymous_variant LOW 240G>T Leu80Leu
M0088224 LFNBLCAP_00141 148983 3 Skin 0.12 protein_coding missense_variant MODERATE 194T>C Ile65Thr
M0088225 LFNBLCAP_00141 148984 3 Skin 0.12 protein_coding missense_variant MODERATE 193A>G Ile65Val
M0088226 LFNBLCAP_00141 148985 3 Skin 0.12 protein_coding synonymous_variant LOW 192C>T Cys64Cys
M0088227 LFNBLCAP_00141 148999 3 Skin 0.12 protein_coding missense_variant MODERATE 178G>A Val60Ile
M0088228 LFNBLCAP_00141 149024 3 Skin 0.12 protein_coding synonymous_variant LOW 153T>C Pro51Pro
M0088229 LFNBLCAP_00141 149087 3 Skin 0.12 protein_coding synonymous_variant LOW 90T>C Phe30Phe
M0088230 LFNBLCAP_00141 149120 3 Skin 0.12 protein_coding synonymous_variant LOW 57T>G Ala19Ala
M0088231 LFNBLCAP_00167 167242 4 Skin 0.15 protein_coding synonymous_variant LOW 111A>G Val37Val
M0088232 LFNBLCAP_00167 167272 3 Skin 0.12 protein_coding synonymous_variant LOW 81C>A Thr27Thr
M0088233 LFNBLCAP_00167 167281 4 Skin 0.15 protein_coding synonymous_variant LOW 72T>C Ile24Ile
M0088234 LFNBLCAP_00168 167376 5 Skin 0.19 protein_coding missense_variant MODERATE 617C>G Thr206Arg
M0088235 LFNBLCAP_00168 167390 6 Skin 0.23 protein_coding synonymous_variant LOW 603A>G Thr201Thr
M0088236 LFNBLCAP_00168 167411 6 Skin 0.23 protein_coding synonymous_variant LOW 582G>C Pro194Pro
M0088237 LFNBLCAP_00168 167413 6 Skin 0.23 protein_coding missense_variant MODERATE 580C>A Pro194Thr
M0088238 LFNBLCAP_00168 167432 5 Skin 0.19 protein_coding synonymous_variant LOW 561G>A Glu187Glu
M0088239 LFNBLCAP_00168 167465 6 Skin 0.23 protein_coding synonymous_variant LOW 528C>G Gly176Gly
M0088240 LFNBLCAP_00168 167480 6 Skin 0.23 protein_coding synonymous_variant LOW 513T>C Leu171Leu
M0088241 LFNBLCAP_00168 167534 6 Skin 0.23 protein_coding synonymous_variant LOW 459T>C Asp153Asp
M0088242 LFNBLCAP_00168 167573 6 Skin 0.23 protein_coding synonymous_variant LOW 420T>C Gly140Gly
M0088243 LFNBLCAP_00168 167600 6 Skin 0.23 protein_coding synonymous_variant LOW 393C>G Arg131Arg
M0088244 LFNBLCAP_00168 167606 6 Skin 0.23 protein_coding missense_variant MODERATE 387G>T Gln129His
M0088245 LFNBLCAP_00168 167618 6 Skin 0.23 protein_coding synonymous_variant LOW 375C>G Arg125Arg
M0088246 LFNBLCAP_00168 167649 6 Skin 0.23 protein_coding missense_variant MODERATE 344G>A Arg115His
M0088247 LFNBLCAP_00168 167650 6 Skin 0.23 protein_coding missense_variant MODERATE 343C>A Arg115Ser
M0088248 LFNBLCAP_00168 167657 6 Skin 0.23 protein_coding synonymous_variant LOW 336G>A Gly112Gly
M0088249 LFNBLCAP_00168 167679 6 Skin 0.23 protein_coding missense_variant MODERATE 314G>A Arg105Lys
M0088250 LFNBLCAP_00168 167690 6 Skin 0.23 protein_coding synonymous_variant LOW 303T>C Ala101Ala
M0088251 LFNBLCAP_00168 167780 6 Skin 0.23 protein_coding synonymous_variant LOW 213A>G Val71Val
M0088252 LFNBLCAP_00168 167886 6 Skin 0.23 protein_coding missense_variant MODERATE 107G>C Ser36Thr
M0088253 LFNBLCAP_00168 167900 6 Skin 0.23 protein_coding synonymous_variant LOW 93C>T Asn31Asn
M0088254 LFNBLCAP_00168 167963 6 Skin 0.23 protein_coding synonymous_variant LOW 30A>G Gly10Gly
M0088255 LFNBLCAP_00168 167841 5 Skin 0.19 protein_coding missense_variant MODERATE 152C>T Ala51Val
M0088256 LFNBLCAP_00165 166644 3 Skin 0.12 protein_coding synonymous_variant LOW 42C>T Val14Val
M0088257 LFNBLCAP_00159 166689 3 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -4093T>C None
M0088258 LFNBLCAP_00166 166738 3 Skin 0.12 protein_coding synonymous_variant LOW 303T>C Asp101Asp
M0088259 LFNBLCAP_00166 166753 3 Skin 0.12 protein_coding synonymous_variant LOW 288G>A Gln96Gln
M0088260 LFNBLCAP_00166 166795 3 Skin 0.12 protein_coding synonymous_variant LOW 246C>G Pro82Pro
M0088261 LFNBLCAP_00166 166891 3 Skin 0.12 protein_coding synonymous_variant LOW 150C>G Thr50Thr
M0088262 LFNBLCAP_00166 166894 3 Skin 0.12 protein_coding synonymous_variant LOW 147T>G Arg49Arg
M0088263 LFNBLCAP_00166 166897 3 Skin 0.12 protein_coding synonymous_variant LOW 144A>C Thr48Thr
M0088264 LFNBLCAP_00166 166898 3 Skin 0.12 protein_coding missense_variant MODERATE 143C>A Thr48Lys
M0088265 LFNBLCAP_00166 166899 3 Skin 0.12 protein_coding missense_variant MODERATE 142A>G Thr48Ala
M0088266 LFNBLCAP_00166 166900 3 Skin 0.12 protein_coding synonymous_variant LOW 141G>C Ser47Ser
M0088267 LFNBLCAP_00166 166915 3 Skin 0.12 protein_coding synonymous_variant LOW 126A>G Lys42Lys
M0088268 LFNBLCAP_00166 166930 3 Skin 0.12 protein_coding synonymous_variant LOW 111C>T Asp37Asp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
LFNBLCAP_00022 Copper (Cu) 100 6.4e-63 1 129 1.0000 1.0000 prediction
LFNBLCAP_00148 Chromium (Cr) 95.8 7.7e-131 1 239 1.0000 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
LFNBLCAP_00040 AOG02746.1|GH23 100 2.37e-213 1 293 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term