Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C453
  Reference Plasmid   NZ_CP016726.2
  Reference Plasmid Size   89016
  Reference Plasmid GC Content   0.34
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0088269 AJIBPJNK_00056 45858 3 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -4227A>G None
M0088270 AJIBPJNK_00056 46256 3 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -4625A>G None
M0088271 AJIBPJNK_00063 46542 3 Skin 0.17 protein_coding synonymous_variant LOW 834A>G Ala278Ala
M0088272 AJIBPJNK_00063 46639 3 Skin 0.17 protein_coding missense_variant MODERATE 737T>C Val246Ala
M0088273 AJIBPJNK_00063 46660 3 Skin 0.17 protein_coding missense_variant MODERATE 716C>T Ala239Val
M0088274 AJIBPJNK_00063 47306 3 Skin 0.17 protein_coding missense_variant MODERATE 70G>A Ala24Thr
M0088275 AJIBPJNK_00064 47631 3 Skin 0.17 protein_coding missense_variant MODERATE 712G>T Ala238Ser
M0088276 AJIBPJNK_00065 48959 3 Skin 0.17 protein_coding missense_variant MODERATE 1702A>G Ile568Val
M0088277 AJIBPJNK_00065 49059 3 Skin 0.17 protein_coding synonymous_variant LOW 1602G>A Val534Val
M0088278 AJIBPJNK_00065 49694 3 Skin 0.17 protein_coding missense_variant MODERATE 967G>A Ala323Thr
M0088279 AJIBPJNK_00065 49704 3 Skin 0.17 protein_coding synonymous_variant LOW 957G>A Leu319Leu
M0088280 AJIBPJNK_00065 50018 3 Skin 0.17 protein_coding missense_variant MODERATE 643C>G Gln215Glu
M0088281 AJIBPJNK_00065 50445 3 Skin 0.17 protein_coding synonymous_variant LOW 216A>G Ala72Ala
M0088282 AJIBPJNK_00065 50480 3 Skin 0.17 protein_coding missense_variant MODERATE 181G>A Val61Ile
M0088283 AJIBPJNK_00065 50654 3 Skin 0.17 protein_coding missense_variant MODERATE 7A>C Lys3Gln
M0088284 AJIBPJNK_00063 50710 3 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -3335T>C None
M0088285 AJIBPJNK_00063 50730 3 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -3355G>A None
M0088286 AJIBPJNK_00066 50797 3 Skin 0.17 protein_coding missense_variant MODERATE 604T>G Leu202Val
M0088287 AJIBPJNK_00066 51021 3 Skin 0.17 protein_coding missense_variant MODERATE 380A>G Lys127Arg
M0088288 AJIBPJNK_00066 51063 3 Skin 0.17 protein_coding missense_variant MODERATE 338G>C Gly113Ala
M0088289 AJIBPJNK_00066 51163 3 Skin 0.17 protein_coding missense_variant MODERATE 238G>A Asp80Asn
M0088290 AJIBPJNK_00067 51596 3 Skin 0.17 protein_coding synonymous_variant LOW 2073C>T Phe691Phe






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
AJIBPJNK_00067 QSR09854.1|GH65 100 0 1 752 1 1
NAHBNJCH_00067 QSR09854.1|GH65 100 0 1 752 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
AJIBPJNK_00091 3.A.1.5.10 88 2.79999999999768e-313 1 600 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily
NAHBNJCH_00091 3.A.1.5.10 88 2.79999999999768e-313 1 600 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.1 The ATP-binding Cassette (ABC) Superfamily