Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C456
  Reference Plasmid   NZ_CP017108.1
  Reference Plasmid Size   279615
  Reference Plasmid GC Content   0.32
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0165946 ONGKMKBB_00070 70552 3 Gut 0.60 protein_coding synonymous_variant LOW 2640A>G Leu880Leu
M0165947 ONGKMKBB_00070 70699 3 Gut 0.60 protein_coding synonymous_variant LOW 2493A>G Lys831Lys
M0165948 ONGKMKBB_00070 70795 3 Gut 0.60 protein_coding synonymous_variant LOW 2397C>T Asp799Asp
M0165949 ONGKMKBB_00070 70840 3 Gut 0.60 protein_coding synonymous_variant LOW 2352A>G Lys784Lys
M0165950 ONGKMKBB_00070 70876 3 Gut 0.60 protein_coding synonymous_variant LOW 2316C>T His772His
M0165951 ONGKMKBB_00070 70888 3 Gut 0.60 protein_coding synonymous_variant LOW 2304T>C Ile768Ile
M0165952 ONGKMKBB_00070 70936 3 Gut 0.60 protein_coding synonymous_variant LOW 2256C>T His752His
M0165953 ONGKMKBB_00070 70954 3 Gut 0.60 protein_coding synonymous_variant LOW 2238T>C Ile746Ile
M0165954 ONGKMKBB_00070 70960 3 Gut 0.60 protein_coding synonymous_variant LOW 2232G>A Leu744Leu
M0165955 ONGKMKBB_00070 70987 3 Gut 0.60 protein_coding synonymous_variant LOW 2205T>A Ala735Ala
M0165956 ONGKMKBB_00070 71158 3 Gut 0.60 protein_coding synonymous_variant LOW 2034T>C Ala678Ala
M0165957 ONGKMKBB_00070 71185 3 Gut 0.60 protein_coding synonymous_variant LOW 2007A>G Leu669Leu
M0165958 ONGKMKBB_00070 71257 3 Gut 0.60 protein_coding synonymous_variant LOW 1935C>T Tyr645Tyr
M0165959 ONGKMKBB_00070 71272 3 Gut 0.60 protein_coding synonymous_variant LOW 1920C>T Tyr640Tyr
M0165960 ONGKMKBB_00070 71323 3 Gut 0.60 protein_coding synonymous_variant LOW 1869T>C Ser623Ser
M0165961 ONGKMKBB_00070 71371 3 Gut 0.60 protein_coding synonymous_variant LOW 1821T>A Ala607Ala
M0165962 ONGKMKBB_00070 71374 3 Gut 0.60 protein_coding synonymous_variant LOW 1818C>T His606His
M0165963 ONGKMKBB_00070 71494 3 Gut 0.60 protein_coding synonymous_variant LOW 1698T>C Tyr566Tyr
M0165964 ONGKMKBB_00070 71500 3 Gut 0.60 protein_coding synonymous_variant LOW 1692C>T Tyr564Tyr
M0165965 ONGKMKBB_00070 71533 3 Gut 0.60 protein_coding synonymous_variant LOW 1659T>C Gly553Gly
M0165966 ONGKMKBB_00070 72091 3 Gut 0.60 protein_coding synonymous_variant LOW 1101G>A Leu367Leu
M0165967 ONGKMKBB_00070 72649 3 Gut 0.60 protein_coding synonymous_variant LOW 543C>T Ser181Ser
M0165968 ONGKMKBB_00070 72793 3 Gut 0.60 protein_coding synonymous_variant LOW 399G>A Leu133Leu
M0165969 ONGKMKBB_00066 73271 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -4995T>A None
M0165970 ONGKMKBB_00068 73535 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -4103A>C None
M0165971 ONGKMKBB_00068 73586 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -4154A>G None
M0165972 ONGKMKBB_00068 73720 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -4288C>T None
M0165973 ONGKMKBB_00068 73907 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -4475G>A None
M0165974 ONGKMKBB_00071 74191 3 Gut 0.60 protein_coding synonymous_variant LOW 189G>C Ala63Ala
M0165975 ONGKMKBB_00072 75393 3 Gut 0.60 protein_coding missense_variant MODERATE 1309A>G Asn437Asp
M0165976 ONGKMKBB_00072 75417 3 Gut 0.60 protein_coding synonymous_variant LOW 1285C>T Leu429Leu
M0165977 ONGKMKBB_00072 75433 3 Gut 0.60 protein_coding synonymous_variant LOW 1269G>A Thr423Thr
M0165978 ONGKMKBB_00072 75571 3 Gut 0.60 protein_coding synonymous_variant LOW 1131T>A Thr377Thr
M0165979 ONGKMKBB_00072 75616 3 Gut 0.60 protein_coding synonymous_variant LOW 1086T>C Ser362Ser
M0165980 ONGKMKBB_00072 75699 3 Gut 0.60 protein_coding missense_variant MODERATE 1003A>C Lys335Gln
M0165981 ONGKMKBB_00072 75865 3 Gut 0.60 protein_coding synonymous_variant LOW 837G>A Gly279Gly
M0165982 ONGKMKBB_00072 75886 3 Gut 0.60 protein_coding synonymous_variant LOW 816C>T Asn272Asn
M0165983 ONGKMKBB_00072 75892 3 Gut 0.60 protein_coding synonymous_variant LOW 810C>T Asn270Asn
M0165984 ONGKMKBB_00072 75916 3 Gut 0.60 protein_coding synonymous_variant LOW 786G>A Leu262Leu
M0165985 ONGKMKBB_00072 75919 3 Gut 0.60 protein_coding synonymous_variant LOW 783A>G Leu261Leu
M0165986 ONGKMKBB_00072 76075 3 Gut 0.60 protein_coding synonymous_variant LOW 627C>T His209His
M0165987 ONGKMKBB_00072 76162 3 Gut 0.60 protein_coding synonymous_variant LOW 540G>A Gln180Gln
M0165988 ONGKMKBB_00072 76180 3 Gut 0.60 protein_coding synonymous_variant LOW 522A>G Lys174Lys
M0165989 ONGKMKBB_00072 76225 3 Gut 0.60 protein_coding synonymous_variant LOW 477T>C Tyr159Tyr
M0165990 ONGKMKBB_00072 76371 3 Gut 0.60 protein_coding synonymous_variant LOW 331T>C Leu111Leu
M0165991 ONGKMKBB_00072 76573 3 Gut 0.60 protein_coding synonymous_variant LOW 129A>G Leu43Leu
M0165992 ONGKMKBB_00072 76657 3 Gut 0.60 protein_coding synonymous_variant LOW 45G>A Gln15Gln
M0165993 ONGKMKBB_00070 76789 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -3598G>A None
M0165994 ONGKMKBB_00070 76913 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -3722A>G None
M0165995 ONGKMKBB_00070 77000 3 Gut 0.60 protein_coding upstream_gene_variant MODIFIER -3809C>T None
M0165996 ONGKMKBB_00073 77127 3 Gut 0.60 protein_coding synonymous_variant LOW 87C>T Tyr29Tyr
M0165997 ONGKMKBB_00073 77569 3 Gut 0.60 protein_coding missense_variant MODERATE 529A>C Thr177Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
DAJNAFJE_00104 2.A.21.3.20 74.5 7.1e-209 1 498 0.9940 0.9960 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.21 The Solute:Sodium Symporter (SSS) Family
ONGKMKBB_00104 2.A.21.3.20 74.5 7.1e-209 1 498 0.9940 0.9960 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.21 The Solute:Sodium Symporter (SSS) Family