Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C483
  Reference Plasmid   NZ_CP022465.2
  Reference Plasmid Size   43860
  Reference Plasmid GC Content   0.42
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0167203 BHFMNADK_00016 26753 4 Gut 0.27 protein_coding synonymous_variant LOW 81A>T Arg27Arg
M0167204 BHFMNADK_00016 26972 4 Gut 0.27 protein_coding synonymous_variant LOW 300A>G Arg100Arg
M0167205 BHFMNADK_00016 27077 3 Gut 0.20 protein_coding synonymous_variant LOW 405T>A Ile135Ile
M0167206 BHFMNADK_00016 27095 3 Gut 0.20 protein_coding synonymous_variant LOW 423C>T Tyr141Tyr
M0167207 BHFMNADK_00016 27125 3 Gut 0.20 protein_coding synonymous_variant LOW 453G>T Thr151Thr
M0167208 BHFMNADK_00016 27128 3 Gut 0.20 protein_coding synonymous_variant LOW 456A>G Lys152Lys
M0167209 BHFMNADK_00015 24278 3 Gut 0.20 protein_coding synonymous_variant LOW 534C>T Leu178Leu
M0167210 BHFMNADK_00015 24279 4 Gut 0.27 protein_coding missense_variant MODERATE 535A>T Ile179Leu
M0167211 BHFMNADK_00015 24374 4 Gut 0.27 protein_coding synonymous_variant LOW 630G>C Val210Val
M0167212 BHFMNADK_00015 24380 4 Gut 0.27 protein_coding synonymous_variant LOW 636T>C Gly212Gly
M0167213 BHFMNADK_00015 24449 4 Gut 0.27 protein_coding synonymous_variant LOW 705T>C Val235Val
M0167214 BHFMNADK_00015 24629 3 Gut 0.20 protein_coding synonymous_variant LOW 885T>C Ile295Ile
M0167215 BHFMNADK_00015 24777 4 Gut 0.27 protein_coding synonymous_variant LOW 1033T>C Leu345Leu
M0167216 BHFMNADK_00015 24986 4 Gut 0.27 protein_coding synonymous_variant LOW 1242A>T Thr414Thr
M0167217 BHFMNADK_00015 25007 4 Gut 0.27 protein_coding synonymous_variant LOW 1263A>G Arg421Arg
M0167218 BHFMNADK_00015 25034 4 Gut 0.27 protein_coding synonymous_variant LOW 1290T>A Ile430Ile
M0167219 BHFMNADK_00015 25067 3 Gut 0.20 protein_coding synonymous_variant LOW 1323T>C His441His
M0167220 BHFMNADK_00015 25119 3 Gut 0.20 protein_coding missense_variant MODERATE 1375A>G Arg459Gly
M0167221 BHFMNADK_00015 25205 4 Gut 0.27 protein_coding synonymous_variant LOW 1461T>C Arg487Arg
M0167222 BHFMNADK_00015 25258 4 Gut 0.27 protein_coding missense_variant MODERATE 1514C>T Thr505Ile
M0167223 BHFMNADK_00015 25283 4 Gut 0.27 protein_coding synonymous_variant LOW 1539A>G Glu513Glu
M0167224 BHFMNADK_00015 25316 4 Gut 0.27 protein_coding missense_variant MODERATE 1572A>G Ile524Met
M0167225 BHFMNADK_00015 25165 3 Gut 0.20 protein_coding missense_variant MODERATE 1421C>T Ala474Val
M0167226 BHFMNADK_00015 25492 3 Gut 0.20 protein_coding missense_variant MODERATE 1748C>A Ala583Asp
M0167227 BHFMNADK_00015 25560 3 Gut 0.20 protein_coding missense_variant MODERATE 1816G>A Glu606Lys
M0167228 BHFMNADK_00015 25588 3 Gut 0.20 protein_coding missense_variant MODERATE 1844A>C His615Pro
M0167229 BHFMNADK_00015 25865 3 Gut 0.20 protein_coding missense_variant MODERATE 2121T>G His707Gln
M0167230 BHFMNADK_00015 25867 3 Gut 0.20 protein_coding missense_variant MODERATE 2123A>G Glu708Gly
M0167231 BHFMNADK_00015 25913 3 Gut 0.20 protein_coding synonymous_variant LOW 2169G>A Thr723Thr
M0167232 BHFMNADK_00015 25999 3 Gut 0.20 protein_coding missense_variant MODERATE 2255A>G Lys752Arg
M0167233 BHFMNADK_00015 26005 3 Gut 0.20 protein_coding missense_variant MODERATE 2261G>A Gly754Glu
M0167234 BHFMNADK_00016 26280 4 Gut 0.27 protein_coding upstream_gene_variant MODIFIER -393A>G None
M0167235 BHFMNADK_00016 26308 4 Gut 0.27 protein_coding upstream_gene_variant MODIFIER -365T>C None
M0167236 BHFMNADK_00016 26335 3 Gut 0.20 protein_coding upstream_gene_variant MODIFIER -338C>T None
M0167237 BHFMNADK_00016 26359 3 Gut 0.20 protein_coding upstream_gene_variant MODIFIER -314G>A None
M0167238 BHFMNADK_00016 26366 3 Gut 0.20 protein_coding upstream_gene_variant MODIFIER -307A>G None
M0167239 BHFMNADK_00016 26377 3 Gut 0.20 protein_coding upstream_gene_variant MODIFIER -296C>T None
M0167240 BHFMNADK_00016 27267 3 Gut 0.20 protein_coding missense_variant MODERATE 595T>C Tyr199His
M0167241 BHFMNADK_00016 27377 3 Gut 0.20 protein_coding synonymous_variant LOW 705T>C Ser235Ser
M0167242 BHFMNADK_00016 27407 3 Gut 0.20 protein_coding synonymous_variant LOW 735T>C Asp245Asp
M0167243 BHFMNADK_00016 27410 3 Gut 0.20 protein_coding synonymous_variant LOW 738C>T Asp246Asp
M0167244 BHFMNADK_00016 27427 3 Gut 0.20 protein_coding missense_variant MODERATE 755G>A Arg252Lys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term