Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C505
  Reference Plasmid   NZ_CP024246.1
  Reference Plasmid Size   36948
  Reference Plasmid GC Content   0.49
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0167552 HKEEFILB_00015 14275 4 Gut 0.24 protein_coding synonymous_variant LOW 42A>C Ser14Ser
M0167553 HKEEFILB_00020 21775 3 Gut 0.18 protein_coding synonymous_variant LOW 105C>T Ala35Ala
M0167554 HKEEFILB_00028 27181 3 Gut 0.18 protein_coding missense_variant MODERATE 62A>G His21Arg
M0167555 HKEEFILB_00026 27748 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -1600G>A None
M0167556 HKEEFILB_00021 22852 3 Gut 0.18 protein_coding missense_variant MODERATE 119C>T Thr40Ile
M0167557 HKEEFILB_00023 23723 3 Gut 0.18 protein_coding synonymous_variant LOW 237T>C Asn79Asn
M0167558 HKEEFILB_00023 23732 3 Gut 0.18 protein_coding synonymous_variant LOW 246T>G Ala82Ala
M0167559 HKEEFILB_00020 24012 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -2133T>C None
M0167560 HKEEFILB_00020 25230 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -3351G>A None
M0167561 HKEEFILB_00026 25918 3 Gut 0.18 protein_coding synonymous_variant LOW 231A>T Arg77Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
HKEEFILB_00020 VFG033834 Pic 98.8 0 1 1348 0.9978 0.9868 Effector delivery system Pic serine protease precursor, autotransporter prediction
HKEEFILB_00024 VFG041000 AAI/SCI-II T6SS 91.5 3.1e-98 1 188 1.0 1 Effector delivery system hypothetical protein prediction
HKEEFILB_00032 VFG017870 Icm/dot type IVB locus 77.9 1e-89 1 208 0.9905 0.9952 Effector delivery system ParA family protein prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term