Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C554
  Reference Plasmid   NZ_CP030934.1
  Reference Plasmid Size   80244
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0168320 GBGKKDIF_00061 57569 5 Gut 0.42 protein_coding synonymous_variant LOW 612C>T Tyr204Tyr
M0168321 GBGKKDIF_00061 57599 5 Gut 0.42 protein_coding synonymous_variant LOW 642C>T Ser214Ser
M0168322 GBGKKDIF_00061 57775 5 Gut 0.42 protein_coding missense_variant MODERATE 818C>T Pro273Leu
M0168323 GBGKKDIF_00062 57883 5 Gut 0.42 protein_coding upstream_gene_variant MODIFIER -290A>C None
M0168324 GBGKKDIF_00062 57897 5 Gut 0.42 protein_coding upstream_gene_variant MODIFIER -276T>G None
M0168325 GBGKKDIF_00013 13350 5 Gut 0.42 protein_coding synonymous_variant LOW 255C>T Ala85Ala
M0168326 GBGKKDIF_00013 13419 5 Gut 0.42 protein_coding synonymous_variant LOW 324G>A Glu108Glu
M0168327 GBGKKDIF_00013 13527 5 Gut 0.42 protein_coding synonymous_variant LOW 432C>T Val144Val
M0168328 GBGKKDIF_00013 13530 5 Gut 0.42 protein_coding synonymous_variant LOW 435C>T Cys145Cys
M0168329 GBGKKDIF_00013 13533 5 Gut 0.42 protein_coding synonymous_variant LOW 438T>C Asn146Asn
M0168330 GBGKKDIF_00013 13539 5 Gut 0.42 protein_coding synonymous_variant LOW 444C>T Ile148Ile
M0168331 GBGKKDIF_00013 13590 5 Gut 0.42 protein_coding synonymous_variant LOW 495T>C Gly165Gly
M0168332 GBGKKDIF_00014 13769 5 Gut 0.42 protein_coding upstream_gene_variant MODIFIER -548G>A None
M0168333 GBGKKDIF_00004 7233 4 Gut 0.33 protein_coding upstream_gene_variant MODIFIER -3047T>C None
M0168334 GBGKKDIF_00004 7244 3 Gut 0.25 protein_coding upstream_gene_variant MODIFIER -3058C>T None
M0168335 GBGKKDIF_00009 7450 3 Gut 0.25 protein_coding synonymous_variant LOW 165G>A Gly55Gly
M0168336 GBGKKDIF_00009 7549 3 Gut 0.25 protein_coding synonymous_variant LOW 264C>T Phe88Phe
M0168337 GBGKKDIF_00009 7750 5 Gut 0.42 protein_coding synonymous_variant LOW 465T>A Leu155Leu
M0168338 GBGKKDIF_00009 7770 5 Gut 0.42 protein_coding missense_variant MODERATE 485G>A Gly162Asp
M0168339 GBGKKDIF_00009 7990 4 Gut 0.33 protein_coding synonymous_variant LOW 705C>A Ala235Ala
M0168340 GBGKKDIF_00010 8498 4 Gut 0.33 protein_coding missense_variant MODERATE 418A>G Thr140Ala
M0168341 GBGKKDIF_00010 8513 4 Gut 0.33 protein_coding synonymous_variant LOW 433T>C Leu145Leu
M0168342 GBGKKDIF_00010 8525 4 Gut 0.33 protein_coding missense_variant MODERATE 445A>T Ser149Cys
M0168343 GBGKKDIF_00010 8527 4 Gut 0.33 protein_coding synonymous_variant LOW 447T>C Ser149Ser
M0168344 GBGKKDIF_00010 8567 4 Gut 0.33 protein_coding missense_variant MODERATE 487G>A Glu163Lys
M0168345 GBGKKDIF_00010 8569 4 Gut 0.33 protein_coding missense_variant MODERATE 489A>T Glu163Asp
M0168346 GBGKKDIF_00010 8590 4 Gut 0.33 protein_coding synonymous_variant LOW 510C>T Gly170Gly
M0168347 GBGKKDIF_00010 8631 4 Gut 0.33 protein_coding missense_variant MODERATE 551A>G Glu184Gly
M0168348 GBGKKDIF_00010 8645 4 Gut 0.33 protein_coding missense_variant MODERATE 565C>T Leu189Phe
M0168349 GBGKKDIF_00010 8647 4 Gut 0.33 protein_coding synonymous_variant LOW 567T>G Leu189Leu
M0168350 GBGKKDIF_00010 8673 4 Gut 0.33 protein_coding missense_variant MODERATE 593T>C Val198Ala
M0168351 GBGKKDIF_00010 8713 4 Gut 0.33 protein_coding missense_variant MODERATE 633T>G Asp211Glu
M0168352 GBGKKDIF_00010 8760 4 Gut 0.33 protein_coding missense_variant MODERATE 680A>G Asn227Ser
M0168353 GBGKKDIF_00010 8791 4 Gut 0.33 protein_coding synonymous_variant LOW 711A>T Ala237Ala
M0168354 GBGKKDIF_00010 8812 4 Gut 0.33 protein_coding synonymous_variant LOW 732A>G Arg244Arg
M0168355 GBGKKDIF_00010 8930 4 Gut 0.33 protein_coding missense_variant MODERATE 850G>T Val284Leu
M0168356 GBGKKDIF_00010 8958 4 Gut 0.33 protein_coding missense_variant MODERATE 878T>C Leu293Ser
M0168357 GBGKKDIF_00010 8977 4 Gut 0.33 protein_coding synonymous_variant LOW 897C>T Ile299Ile
M0168358 GBGKKDIF_00010 9007 4 Gut 0.33 protein_coding synonymous_variant LOW 927A>G Val309Val
M0168359 GBGKKDIF_00010 9014 4 Gut 0.33 protein_coding missense_variant MODERATE 934A>G Thr312Ala
M0168360 GBGKKDIF_00010 9016 4 Gut 0.33 protein_coding synonymous_variant LOW 936A>G Thr312Thr
M0168361 GBGKKDIF_00010 9064 4 Gut 0.33 protein_coding synonymous_variant LOW 984G>A Gly328Gly
M0168362 GBGKKDIF_00010 9074 4 Gut 0.33 protein_coding synonymous_variant LOW 994T>C Leu332Leu
M0168363 GBGKKDIF_00010 9130 4 Gut 0.33 protein_coding synonymous_variant LOW 1050G>A Lys350Lys
M0168364 GBGKKDIF_00010 9131 4 Gut 0.33 protein_coding synonymous_variant LOW 1051C>T Leu351Leu
M0168365 GBGKKDIF_00010 9187 4 Gut 0.33 protein_coding synonymous_variant LOW 1107G>A Glu369Glu
M0168366 GBGKKDIF_00010 9244 4 Gut 0.33 protein_coding synonymous_variant LOW 1164C>T Asp388Asp
M0168367 GBGKKDIF_00010 9323 4 Gut 0.33 protein_coding missense_variant MODERATE 1243C>A Gln415Lys
M0168368 GBGKKDIF_00010 9326 4 Gut 0.33 protein_coding missense_variant MODERATE 1246A>G Thr416Ala
M0168369 GBGKKDIF_00010 9334 4 Gut 0.33 protein_coding synonymous_variant LOW 1254C>T Asn418Asn
M0168370 GBGKKDIF_00010 9340 4 Gut 0.33 protein_coding synonymous_variant LOW 1260T>G Ser420Ser
M0168371 GBGKKDIF_00010 9360 4 Gut 0.33 protein_coding missense_variant MODERATE 1280T>C Val427Ala
M0168372 GBGKKDIF_00010 9395 4 Gut 0.33 protein_coding synonymous_variant LOW 1315C>T Leu439Leu
M0168373 GBGKKDIF_00010 9415 4 Gut 0.33 protein_coding synonymous_variant LOW 1335A>G Thr445Thr
M0168374 GBGKKDIF_00010 9499 4 Gut 0.33 protein_coding synonymous_variant LOW 1419A>G Pro473Pro
M0168375 GBGKKDIF_00010 9531 4 Gut 0.33 protein_coding missense_variant MODERATE 1451A>C Asp484Ala
M0168376 GBGKKDIF_00010 9552 4 Gut 0.33 protein_coding missense_variant MODERATE 1472A>G His491Arg
M0168377 GBGKKDIF_00010 9673 4 Gut 0.33 protein_coding synonymous_variant LOW 1593T>C Phe531Phe
M0168378 GBGKKDIF_00010 9680 4 Gut 0.33 protein_coding missense_variant MODERATE 1600C>A Leu534Met
M0168379 GBGKKDIF_00010 9766 4 Gut 0.33 protein_coding synonymous_variant LOW 1686G>A Glu562Glu
M0168380 GBGKKDIF_00010 9769 4 Gut 0.33 protein_coding synonymous_variant LOW 1689T>C Asp563Asp
M0168381 GBGKKDIF_00010 9793 4 Gut 0.33 protein_coding synonymous_variant LOW 1713C>T Tyr571Tyr
M0168382 GBGKKDIF_00010 9813 4 Gut 0.33 protein_coding missense_variant MODERATE 1733C>A Ala578Asp
M0168383 GBGKKDIF_00010 9821 4 Gut 0.33 protein_coding missense_variant MODERATE 1741A>G Arg581Gly
M0168384 GBGKKDIF_00010 9823 4 Gut 0.33 protein_coding missense_variant MODERATE 1743A>T Arg581Ser
M0168385 GBGKKDIF_00010 9844 4 Gut 0.33 protein_coding synonymous_variant LOW 1764G>A Gly588Gly
M0168386 GBGKKDIF_00010 9893 4 Gut 0.33 protein_coding missense_variant MODERATE 1813T>G Phe605Val
M0168387 GBGKKDIF_00010 9911 4 Gut 0.33 protein_coding missense_variant MODERATE 1831G>A Val611Ile
M0168388 GBGKKDIF_00010 9913 4 Gut 0.33 protein_coding synonymous_variant LOW 1833A>G Val611Val
M0168389 GBGKKDIF_00010 9922 4 Gut 0.33 protein_coding missense_variant MODERATE 1842C>A Asp614Glu
M0168390 GBGKKDIF_00010 9931 4 Gut 0.33 protein_coding synonymous_variant LOW 1851T>C Ile617Ile
M0168391 GBGKKDIF_00010 9949 4 Gut 0.33 protein_coding synonymous_variant LOW 1869A>G Gln623Gln
M0168392 GBGKKDIF_00010 9974 4 Gut 0.33 protein_coding missense_variant MODERATE 1894G>A Glu632Lys
M0168393 GBGKKDIF_00010 9988 4 Gut 0.33 protein_coding synonymous_variant LOW 1908T>C Tyr636Tyr
M0168394 GBGKKDIF_00010 10001 4 Gut 0.33 protein_coding missense_variant MODERATE 1921A>C Asn641His
M0168395 GBGKKDIF_00010 10016 4 Gut 0.33 protein_coding missense_variant MODERATE 1936G>A Gly646Arg
M0168396 GBGKKDIF_00010 10018 4 Gut 0.33 protein_coding synonymous_variant LOW 1938A>C Gly646Gly
M0168397 GBGKKDIF_00010 10019 4 Gut 0.33 protein_coding synonymous_variant LOW 1939C>T Leu647Leu
M0168398 GBGKKDIF_00010 10024 4 Gut 0.33 protein_coding synonymous_variant LOW 1944C>T Ala648Ala
M0168399 GBGKKDIF_00010 10039 4 Gut 0.33 protein_coding synonymous_variant LOW 1959T>C Ile653Ile
M0168400 GBGKKDIF_00010 10043 4 Gut 0.33 protein_coding missense_variant MODERATE 1963A>G Ser655Gly
M0168401 GBGKKDIF_00010 10045 4 Gut 0.33 protein_coding synonymous_variant LOW 1965C>T Ser655Ser
M0168402 GBGKKDIF_00010 10048 4 Gut 0.33 protein_coding synonymous_variant LOW 1968A>G Val656Val
M0168403 GBGKKDIF_00010 10069 4 Gut 0.33 protein_coding synonymous_variant LOW 1989C>A Ala663Ala
M0168404 GBGKKDIF_00010 10084 4 Gut 0.33 protein_coding missense_variant MODERATE 2004G>T Leu668Phe
M0168405 GBGKKDIF_00010 10171 4 Gut 0.33 protein_coding synonymous_variant LOW 2091C>T Asp697Asp
M0168406 GBGKKDIF_00010 10198 4 Gut 0.33 protein_coding synonymous_variant LOW 2118G>T Val706Val
M0168407 GBGKKDIF_00010 10204 4 Gut 0.33 protein_coding synonymous_variant LOW 2124C>T Asp708Asp
M0168408 GBGKKDIF_00010 10231 4 Gut 0.33 protein_coding synonymous_variant LOW 2151C>T Tyr717Tyr
M0168409 GBGKKDIF_00010 10237 4 Gut 0.33 protein_coding missense_variant MODERATE 2157T>G Asp719Glu
M0168410 GBGKKDIF_00010 10255 4 Gut 0.33 protein_coding missense_variant MODERATE 2175T>A Asp725Glu
M0168411 GBGKKDIF_00010 10279 4 Gut 0.33 protein_coding synonymous_variant LOW 2199A>G Gln733Gln
M0168412 GBGKKDIF_00010 10348 4 Gut 0.33 protein_coding synonymous_variant LOW 2268G>A Ala756Ala
M0168413 GBGKKDIF_00010 10390 4 Gut 0.33 protein_coding synonymous_variant LOW 2310G>T Ser770Ser
M0168414 GBGKKDIF_00010 10465 4 Gut 0.33 protein_coding synonymous_variant LOW 2385G>C Thr795Thr
M0168415 GBGKKDIF_00010 10477 4 Gut 0.33 protein_coding synonymous_variant LOW 2397T>C Phe799Phe
M0168416 GBGKKDIF_00010 10500 4 Gut 0.33 protein_coding missense_variant MODERATE 2420A>C Asn807Thr
M0168417 GBGKKDIF_00010 10527 4 Gut 0.33 protein_coding missense_variant MODERATE 2447A>T Glu816Val
M0168418 GBGKKDIF_00010 10570 4 Gut 0.33 protein_coding synonymous_variant LOW 2490C>T Gly830Gly
M0168419 GBGKKDIF_00010 10585 4 Gut 0.33 protein_coding synonymous_variant LOW 2505C>T Tyr835Tyr
M0168420 GBGKKDIF_00010 10589 4 Gut 0.33 protein_coding synonymous_variant LOW 2509T>C Leu837Leu
M0168421 GBGKKDIF_00010 10618 4 Gut 0.33 protein_coding synonymous_variant LOW 2538T>C Leu846Leu
M0168422 GBGKKDIF_00010 10687 4 Gut 0.33 protein_coding synonymous_variant LOW 2607C>T His869His
M0168423 GBGKKDIF_00010 10696 4 Gut 0.33 protein_coding synonymous_variant LOW 2616A>G Ala872Ala
M0168424 GBGKKDIF_00010 10729 4 Gut 0.33 protein_coding synonymous_variant LOW 2649T>A Val883Val
M0168425 GBGKKDIF_00010 10858 4 Gut 0.33 protein_coding synonymous_variant LOW 2778T>C Val926Val
M0168426 GBGKKDIF_00010 10861 4 Gut 0.33 protein_coding synonymous_variant LOW 2781C>T Pro927Pro
M0168427 GBGKKDIF_00010 10885 4 Gut 0.33 protein_coding synonymous_variant LOW 2805T>C Asn935Asn
M0168428 GBGKKDIF_00010 11056 4 Gut 0.33 protein_coding synonymous_variant LOW 2976C>T Ile992Ile
M0168429 GBGKKDIF_00010 11228 4 Gut 0.33 protein_coding missense_variant MODERATE 3148G>T Ala1050Ser
M0168430 GBGKKDIF_00010 11260 4 Gut 0.33 protein_coding synonymous_variant LOW 3180C>T Phe1060Phe
M0168431 GBGKKDIF_00010 11277 4 Gut 0.33 protein_coding missense_variant MODERATE 3197G>A Ser1066Asn
M0168432 GBGKKDIF_00011 11329 4 Gut 0.33 protein_coding upstream_gene_variant MODIFIER -118G>A None
M0168433 GBGKKDIF_00011 11446 4 Gut 0.33 protein_coding upstream_gene_variant MODIFIER -1T>C None
M0168434 GBGKKDIF_00011 11536 4 Gut 0.33 protein_coding synonymous_variant LOW 90G>A Ala30Ala
M0168435 GBGKKDIF_00011 11542 4 Gut 0.33 protein_coding synonymous_variant LOW 96T>C Val32Val
M0168436 GBGKKDIF_00011 11548 4 Gut 0.33 protein_coding synonymous_variant LOW 102A>G Ala34Ala
M0168437 GBGKKDIF_00011 11578 4 Gut 0.33 protein_coding synonymous_variant LOW 132G>A Leu44Leu
M0168438 GBGKKDIF_00011 11584 4 Gut 0.33 protein_coding synonymous_variant LOW 138A>G Thr46Thr
M0168439 GBGKKDIF_00011 11596 4 Gut 0.33 protein_coding synonymous_variant LOW 150G>A Thr50Thr
M0168440 GBGKKDIF_00011 11737 4 Gut 0.33 protein_coding synonymous_variant LOW 291A>G Gly97Gly
M0168441 GBGKKDIF_00011 11747 4 Gut 0.33 protein_coding missense_variant MODERATE 301G>A Val101Ile
M0168442 GBGKKDIF_00011 11977 4 Gut 0.33 protein_coding synonymous_variant LOW 531A>G Ala177Ala
M0168443 GBGKKDIF_00011 11989 4 Gut 0.33 protein_coding synonymous_variant LOW 543C>T Asp181Asp
M0168444 GBGKKDIF_00011 12006 4 Gut 0.33 protein_coding missense_variant MODERATE 560G>A Ser187Asn
M0168445 GBGKKDIF_00011 12020 4 Gut 0.33 protein_coding missense_variant MODERATE 574T>G Ser192Ala
M0168446 GBGKKDIF_00012 12250 4 Gut 0.33 protein_coding synonymous_variant LOW 111C>T Asp37Asp
M0168447 GBGKKDIF_00012 12334 4 Gut 0.33 protein_coding synonymous_variant LOW 195A>G Pro65Pro
M0168448 GBGKKDIF_00012 12340 4 Gut 0.33 protein_coding synonymous_variant LOW 201G>T Ala67Ala
M0168449 GBGKKDIF_00012 12346 4 Gut 0.33 protein_coding synonymous_variant LOW 207C>G Gly69Gly
M0168450 GBGKKDIF_00012 12351 4 Gut 0.33 protein_coding missense_variant MODERATE 212G>T Ser71Ile
M0168451 GBGKKDIF_00012 12403 4 Gut 0.33 protein_coding synonymous_variant LOW 264G>A Lys88Lys
M0168452 GBGKKDIF_00012 12595 4 Gut 0.33 protein_coding synonymous_variant LOW 456C>T Asn152Asn
M0168453 GBGKKDIF_00012 12637 4 Gut 0.33 protein_coding synonymous_variant LOW 498A>T Ser166Ser
M0168454 GBGKKDIF_00012 12640 4 Gut 0.33 protein_coding synonymous_variant LOW 501A>G Thr167Thr
M0168455 GBGKKDIF_00012 12643 4 Gut 0.33 protein_coding synonymous_variant LOW 504A>G Val168Val
M0168456 GBGKKDIF_00012 12646 4 Gut 0.33 protein_coding synonymous_variant LOW 507T>C Gly169Gly
M0168457 GBGKKDIF_00012 12649 4 Gut 0.33 protein_coding synonymous_variant LOW 510G>A Pro170Pro
M0168458 GBGKKDIF_00012 12676 4 Gut 0.33 protein_coding synonymous_variant LOW 537A>T Ala179Ala
M0168459 GBGKKDIF_00012 12691 4 Gut 0.33 protein_coding synonymous_variant LOW 552C>T Ile184Ile
M0168460 GBGKKDIF_00012 12700 4 Gut 0.33 protein_coding synonymous_variant LOW 561T>C Ala187Ala
M0168461 GBGKKDIF_00012 12706 4 Gut 0.33 protein_coding synonymous_variant LOW 567G>A Gly189Gly
M0168462 GBGKKDIF_00012 12712 4 Gut 0.33 protein_coding synonymous_variant LOW 573C>A Gly191Gly
M0168463 GBGKKDIF_00012 12718 4 Gut 0.33 protein_coding synonymous_variant LOW 579G>A Val193Val
M0168464 GBGKKDIF_00012 12721 4 Gut 0.33 protein_coding synonymous_variant LOW 582T>C Ile194Ile
M0168465 GBGKKDIF_00012 12730 4 Gut 0.33 protein_coding synonymous_variant LOW 591A>G Leu197Leu
M0168466 GBGKKDIF_00012 12736 4 Gut 0.33 protein_coding synonymous_variant LOW 597A>G Ala199Ala
M0168467 GBGKKDIF_00012 12742 4 Gut 0.33 protein_coding synonymous_variant LOW 603A>G Val201Val
M0168468 GBGKKDIF_00012 12775 4 Gut 0.33 protein_coding synonymous_variant LOW 636T>C Ile212Ile
M0168469 GBGKKDIF_00012 12797 4 Gut 0.33 protein_coding synonymous_variant LOW 658C>T Leu220Leu
M0168470 GBGKKDIF_00012 12805 4 Gut 0.33 protein_coding synonymous_variant LOW 666A>G Thr222Thr
M0168471 GBGKKDIF_00012 12823 4 Gut 0.33 protein_coding synonymous_variant LOW 684T>C Ala228Ala
M0168472 GBGKKDIF_00012 12832 4 Gut 0.33 protein_coding synonymous_variant LOW 693C>T Ala231Ala
M0168473 GBGKKDIF_00012 12838 4 Gut 0.33 protein_coding synonymous_variant LOW 699A>G Thr233Thr
M0168474 GBGKKDIF_00012 12937 4 Gut 0.33 protein_coding synonymous_variant LOW 798T>C Thr266Thr
M0168475 GBGKKDIF_00012 13012 4 Gut 0.33 protein_coding synonymous_variant LOW 873G>A Val291Val
M0168476 GBGKKDIF_00012 13018 4 Gut 0.33 protein_coding synonymous_variant LOW 879G>A Lys293Lys
M0168477 GBGKKDIF_00012 13045 4 Gut 0.33 protein_coding synonymous_variant LOW 906T>C Phe302Phe
M0168478 GBGKKDIF_00013 13197 4 Gut 0.33 protein_coding synonymous_variant LOW 102C>T Ile34Ile
M0168479 GBGKKDIF_00013 13203 4 Gut 0.33 protein_coding synonymous_variant LOW 108T>C Gly36Gly
M0168480 GBGKKDIF_00013 13210 4 Gut 0.33 protein_coding missense_variant MODERATE 115G>A Val39Ile
M0168481 GBGKKDIF_00013 13218 4 Gut 0.33 protein_coding synonymous_variant LOW 123G>A Lys41Lys
M0168482 GBGKKDIF_00013 13371 4 Gut 0.33 protein_coding synonymous_variant LOW 276C>T Arg92Arg
M0168483 GBGKKDIF_00013 13593 4 Gut 0.33 protein_coding synonymous_variant LOW 498C>A Gly166Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
GBGKKDIF_00016 PHI:5205 HMPREF0351_10118 (WxL locusC) 94.6 6.5e-216 29 420 0.9333 1.0000 rodents endocarditis involved in bile salt stress and endocarditis pathogenesis reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
GBGKKDIF_00074 AXG40753.1|GH23 100 1.61e-272 1 369 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
GBGKKDIF_00002 3.A.7.14.1 86.5 9e-115 1 261 1.0000 1.5410 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBGKKDIF_00068 3.A.7.14.1 97.1 0 1 654 1.0000 3.5738 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBGKKDIF_00071 3.A.7.14.1 98.9 2.8e-105 1 190 1.0000 1.0383 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBGKKDIF_00072 3.A.7.14.1 98.3 0 1 653 1.0000 3.5683 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBGKKDIF_00073 3.A.7.14.1 97.3 4.8e-241 1 450 1.0000 2.4590 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBGKKDIF_00074 3.A.7.14.1 97.8 1.3e-212 1 369 1.0000 2.0164 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBGKKDIF_00075 3.A.7.14.1 95.1 9.2e-90 1 183 1.0000 1.0000 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBGKKDIF_00076 3.A.7.14.1 97.9 1.8e-69 1 143 1.0000 0.7814 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBGKKDIF_00077 3.A.7.14.1 98.4 6.6e-309 1 551 1.0000 3.0109 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBGKKDIF_00078 3.A.7.14.1 86.9 1.1e-151 1 306 0.9967 1.6721 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBGKKDIF_00079 3.A.7.14.1 92.3 4.4e-153 1 310 1.0000 1.6940 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family
GBGKKDIF_00080 3.A.7.14.1 97.8 1.3e-166 1 322 1.0000 1.7596 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.7 The Type IV (Conjugal DNA-Protein Transfer or VirB) Secretory Pathway (IVSP) Family