Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C555
  Reference Plasmid   NZ_CP030935.1
  Reference Plasmid Size   82704
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0168484 FEOACDMG_00065 68139 8 Gut 0.36 protein_coding upstream_gene_variant MODIFIER -4923C>G None
M0168485 FEOACDMG_00073 69212 11 Gut 0.50 protein_coding missense_variant MODERATE 14T>C Ile5Thr
M0168486 FEOACDMG_00074 70206 11 Gut 0.50 protein_coding missense_variant MODERATE 75C>G Asn25Lys
M0168487 FEOACDMG_00074 70362 7 Gut 0.32 protein_coding synonymous_variant LOW 231C>T Phe77Phe
M0168488 FEOACDMG_00075 71164 3 Gut 0.14 protein_coding stop_gained HIGH 710G>A Trp237*
M0168489 FEOACDMG_00075 71177 3 Gut 0.14 protein_coding synonymous_variant LOW 723G>A Ser241Ser
M0168490 FEOACDMG_00075 71254 9 Gut 0.41 protein_coding missense_variant MODERATE 800C>A Ser267Tyr
M0168491 FEOACDMG_00075 71275 9 Gut 0.41 protein_coding missense_variant MODERATE 821G>A Arg274Lys
M0168492 FEOACDMG_00076 71361 9 Gut 0.41 protein_coding upstream_gene_variant MODIFIER -95T>C None
M0168493 FEOACDMG_00065 68185 3 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -4969A>T None
M0168494 FEOACDMG_00075 70681 7 Gut 0.32 protein_coding missense_variant MODERATE 227T>G Leu76Arg
M0168495 FEOACDMG_00075 70747 4 Gut 0.18 protein_coding missense_variant MODERATE 293G>T Gly98Val
M0168496 FEOACDMG_00075 70751 4 Gut 0.18 protein_coding synonymous_variant LOW 297A>G Gly99Gly
M0168497 FEOACDMG_00075 70898 4 Gut 0.18 protein_coding synonymous_variant LOW 444T>A Gly148Gly
M0168498 FEOACDMG_00077 73700 4 Gut 0.18 protein_coding synonymous_variant LOW 1692A>G Lys564Lys
M0168499 FEOACDMG_00030 27995 3 Gut 0.14 protein_coding missense_variant MODERATE 55A>G Ile19Val
M0168500 FEOACDMG_00030 28069 3 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -20C>T None
M0168501 FEOACDMG_00030 28072 3 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -23G>A None
M0168502 FEOACDMG_00030 28087 3 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -38T>G None
M0168503 FEOACDMG_00030 28098 3 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -49T>C None
M0168504 FEOACDMG_00030 28103 3 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -54C>A None
M0168505 FEOACDMG_00031 28142 3 Gut 0.14 protein_coding missense_variant MODERATE 167G>A Gly56Glu
M0168506 FEOACDMG_00031 28189 3 Gut 0.14 protein_coding synonymous_variant LOW 120C>T Tyr40Tyr
M0168507 FEOACDMG_00031 28218 3 Gut 0.14 protein_coding missense_variant MODERATE 91G>T Val31Phe
M0168508 FEOACDMG_00031 28269 3 Gut 0.14 protein_coding missense_variant MODERATE 40A>T Met14Leu
M0168509 FEOACDMG_00031 28308 3 Gut 0.14 protein_coding missense_variant MODERATE 1G>A Val1Met
M0168510 FEOACDMG_00032 28611 3 Gut 0.14 protein_coding synonymous_variant LOW 105C>T His35His
M0168511 FEOACDMG_00032 28617 3 Gut 0.14 protein_coding synonymous_variant LOW 99G>A Lys33Lys
M0168512 FEOACDMG_00032 28641 3 Gut 0.14 protein_coding synonymous_variant LOW 75C>T Tyr25Tyr
M0168513 FEOACDMG_00032 28704 3 Gut 0.14 protein_coding synonymous_variant LOW 12A>G Glu4Glu
M0168514 FEOACDMG_00032 28713 3 Gut 0.14 protein_coding start_lost HIGH 3G>A Met1?
M0168515 FEOACDMG_00030 28721 3 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -672A>G None
M0168516 FEOACDMG_00030 28896 3 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -847A>G None
M0168517 FEOACDMG_00030 28900 3 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -851G>A None
M0168518 FEOACDMG_00030 28905 3 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -856C>T None
M0168519 FEOACDMG_00030 28942 3 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -893A>G None
M0168520 FEOACDMG_00030 28965 3 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -916A>C None
M0168521 FEOACDMG_00033 29028 3 Gut 0.14 protein_coding missense_variant MODERATE 911T>C Val304Ala
M0168522 FEOACDMG_00033 29162 3 Gut 0.14 protein_coding synonymous_variant LOW 777A>G Val259Val
M0168523 FEOACDMG_00033 29469 3 Gut 0.14 protein_coding missense_variant MODERATE 470A>G Asn157Ser
M0168524 FEOACDMG_00033 29471 3 Gut 0.14 protein_coding synonymous_variant LOW 468G>A Leu156Leu
M0168525 FEOACDMG_00033 29492 3 Gut 0.14 protein_coding synonymous_variant LOW 447C>A Ala149Ala
M0168526 FEOACDMG_00033 29525 3 Gut 0.14 protein_coding synonymous_variant LOW 414C>T Phe138Phe
M0168527 FEOACDMG_00033 29532 3 Gut 0.14 protein_coding missense_variant MODERATE 407G>A Arg136Lys
M0168528 FEOACDMG_00033 29549 3 Gut 0.14 protein_coding synonymous_variant LOW 390T>C Pro130Pro
M0168529 FEOACDMG_00033 29558 3 Gut 0.14 protein_coding missense_variant MODERATE 381T>G Asn127Lys
M0168530 FEOACDMG_00033 29562 3 Gut 0.14 protein_coding missense_variant MODERATE 377A>G Glu126Gly
M0168531 FEOACDMG_00033 29577 3 Gut 0.14 protein_coding missense_variant MODERATE 362T>C Met121Thr
M0168532 FEOACDMG_00033 29582 3 Gut 0.14 protein_coding missense_variant MODERATE 357A>C Arg119Ser
M0168533 FEOACDMG_00033 29624 3 Gut 0.14 protein_coding synonymous_variant LOW 315A>G Ala105Ala
M0168534 FEOACDMG_00033 29732 3 Gut 0.14 protein_coding synonymous_variant LOW 207T>G Ser69Ser
M0168535 FEOACDMG_00033 29750 3 Gut 0.14 protein_coding synonymous_variant LOW 189T>A Ser63Ser
M0168536 FEOACDMG_00033 29753 3 Gut 0.14 protein_coding synonymous_variant LOW 186C>T Ala62Ala
M0168537 FEOACDMG_00033 29771 3 Gut 0.14 protein_coding synonymous_variant LOW 168C>T Thr56Thr
M0168538 FEOACDMG_00033 29774 3 Gut 0.14 protein_coding synonymous_variant LOW 165A>G Leu55Leu
M0168539 FEOACDMG_00033 29779 3 Gut 0.14 protein_coding missense_variant MODERATE 160A>G Ile54Val
M0168540 FEOACDMG_00033 29780 3 Gut 0.14 protein_coding synonymous_variant LOW 159T>A Thr53Thr
M0168541 FEOACDMG_00033 29786 3 Gut 0.14 protein_coding synonymous_variant LOW 153T>C Gly51Gly
M0168542 FEOACDMG_00033 29803 3 Gut 0.14 protein_coding missense_variant MODERATE 136A>G Asn46Asp
M0168543 FEOACDMG_00033 29804 3 Gut 0.14 protein_coding missense_variant MODERATE 135T>G Asp45Glu
M0168544 FEOACDMG_00033 29813 3 Gut 0.14 protein_coding synonymous_variant LOW 126C>T Ile42Ile
M0168545 FEOACDMG_00033 29818 3 Gut 0.14 protein_coding missense_variant MODERATE 121A>G Ser41Gly
M0168546 FEOACDMG_00033 29822 3 Gut 0.14 protein_coding synonymous_variant LOW 117G>T Ser39Ser
M0168547 FEOACDMG_00033 29840 3 Gut 0.14 protein_coding synonymous_variant LOW 99G>A Glu33Glu
M0168548 FEOACDMG_00033 29860 3 Gut 0.14 protein_coding missense_variant MODERATE 79G>A Ala27Thr
M0168549 FEOACDMG_00030 30006 3 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -1957T>C None
M0168550 FEOACDMG_00030 30021 3 Gut 0.14 protein_coding upstream_gene_variant MODIFIER -1972T>G None
M0168551 FEOACDMG_00035 31064 3 Gut 0.14 protein_coding synonymous_variant LOW 90A>C Gly30Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
FEOACDMG_00002 Arsenic (As), Antimony (Sb) 79.5 2e-151 1 347 0.9639 0.9720 prediction
FEOACDMG_00003 Arsenic (As) 73.8 5.9e-55 18 147 0.8387 0.9701 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
FEOACDMG_00002 2.A.59.1.5 72.4 2.2e-135 8 347 0.9444 1.1486 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.59 The Arsenical Resistance-3 (ACR3) Family