Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C558
  Reference Plasmid   NZ_CP031160.1
  Reference Plasmid Size   70951
  Reference Plasmid GC Content   0.61
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0094257 MONJFEAB_00063 54938 5 Skin 0.10 protein_coding synonymous_variant LOW 936G>A Ser312Ser
M0094258 MONJFEAB_00058 55885 6 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -4682T>C None
M0094259 MONJFEAB_00058 55984 6 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -4781C>T None
M0094260 MONJFEAB_00059 56635 6 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -4283T>A None
M0094261 MONJFEAB_00020 22934 6 Skin 0.12 protein_coding synonymous_variant LOW 501C>T Asp167Asp
M0094262 MONJFEAB_00021 23255 9 Skin 0.17 protein_coding synonymous_variant LOW 141C>T His47His
M0094263 MONJFEAB_00021 23320 8 Skin 0.15 protein_coding missense_variant MODERATE 206T>C Val69Ala
M0094264 MONJFEAB_00021 23459 12 Skin 0.23 protein_coding synonymous_variant LOW 345A>G Leu115Leu
M0094265 MONJFEAB_00021 24184 9 Skin 0.17 protein_coding missense_variant MODERATE 1070G>C Trp357Ser
M0094266 MONJFEAB_00023 24224 11 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -1180G>A None
M0094267 MONJFEAB_00023 24241 11 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -1163A>G None
M0094268 MONJFEAB_00022 24294 8 Skin 0.15 protein_coding synonymous_variant LOW 1038A>G Glu346Glu
M0094269 MONJFEAB_00022 24311 8 Skin 0.15 protein_coding missense_variant MODERATE 1021G>A Gly341Arg
M0094270 MONJFEAB_00022 24348 10 Skin 0.19 protein_coding synonymous_variant LOW 984T>C His328His
M0094271 MONJFEAB_00022 24497 12 Skin 0.23 protein_coding missense_variant MODERATE 835C>T His279Tyr
M0094272 MONJFEAB_00022 24528 10 Skin 0.19 protein_coding synonymous_variant LOW 804A>G Ala268Ala
M0094273 MONJFEAB_00022 24537 11 Skin 0.21 protein_coding synonymous_variant LOW 795C>A Leu265Leu
M0094274 MONJFEAB_00022 24956 5 Skin 0.10 protein_coding missense_variant MODERATE 376T>C Tyr126His
M0094275 MONJFEAB_00016 20339 7 Skin 0.13 protein_coding missense_variant MODERATE 112G>T Val38Phe
M0094276 MONJFEAB_00016 20341 7 Skin 0.13 protein_coding synonymous_variant LOW 114T>C Val38Val
M0094277 MONJFEAB_00016 20342 6 Skin 0.12 protein_coding missense_variant MODERATE 115G>A Val39Ile
M0094278 MONJFEAB_00016 20347 7 Skin 0.13 protein_coding synonymous_variant LOW 120T>A Pro40Pro
M0094279 MONJFEAB_00016 20350 7 Skin 0.13 protein_coding synonymous_variant LOW 123A>G Gly41Gly
M0094280 MONJFEAB_00016 20353 7 Skin 0.13 protein_coding synonymous_variant LOW 126C>G Leu42Leu
M0094281 MONJFEAB_00016 20359 7 Skin 0.13 protein_coding synonymous_variant LOW 132A>G Leu44Leu
M0094282 MONJFEAB_00016 20428 8 Skin 0.15 protein_coding synonymous_variant LOW 201G>A Leu67Leu
M0094283 MONJFEAB_00016 20433 6 Skin 0.12 protein_coding missense_variant MODERATE 206G>A Gly69Glu
M0094284 MONJFEAB_00016 20489 7 Skin 0.13 protein_coding missense_variant MODERATE 262G>A Val88Ile
M0094285 MONJFEAB_00016 20492 7 Skin 0.13 protein_coding missense_variant MODERATE 265G>A Val89Met
M0094286 MONJFEAB_00016 20521 7 Skin 0.13 protein_coding synonymous_variant LOW 294C>T Ala98Ala
M0094287 MONJFEAB_00016 20530 6 Skin 0.12 protein_coding synonymous_variant LOW 303G>C Leu101Leu
M0094288 MONJFEAB_00016 20608 6 Skin 0.12 protein_coding synonymous_variant LOW 381C>T Ile127Ile
M0094289 MONJFEAB_00016 20611 6 Skin 0.12 protein_coding synonymous_variant LOW 384A>G Pro128Pro
M0094290 MONJFEAB_00016 20632 6 Skin 0.12 protein_coding synonymous_variant LOW 405T>C Ile135Ile
M0094291 MONJFEAB_00016 20644 6 Skin 0.12 protein_coding synonymous_variant LOW 417T>C Gly139Gly
M0094292 MONJFEAB_00016 20692 6 Skin 0.12 protein_coding synonymous_variant LOW 465T>C Ala155Ala
M0094293 MONJFEAB_00016 20695 6 Skin 0.12 protein_coding synonymous_variant LOW 468G>A Gly156Gly
M0094294 MONJFEAB_00016 20702 6 Skin 0.12 protein_coding missense_variant MODERATE 475G>A Ala159Thr
M0094295 MONJFEAB_00016 20752 7 Skin 0.13 protein_coding synonymous_variant LOW 525T>G Leu175Leu
M0094296 MONJFEAB_00016 20756 7 Skin 0.13 protein_coding missense_variant MODERATE 529T>G Phe177Val
M0094297 MONJFEAB_00016 20761 7 Skin 0.13 protein_coding synonymous_variant LOW 534T>C Leu178Leu
M0094298 MONJFEAB_00016 20770 7 Skin 0.13 protein_coding synonymous_variant LOW 543A>G Gln181Gln
M0094299 MONJFEAB_00016 20777 7 Skin 0.13 protein_coding missense_variant MODERATE 550A>G Arg184Gly
M0094300 MONJFEAB_00016 20799 6 Skin 0.12 protein_coding splice_region_variant&stop_retained_variant LOW 572G>A Ter191Ter
M0094301 MONJFEAB_00017 20806 6 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -22C>T None
M0094302 MONJFEAB_00017 20825 6 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -3G>T None
M0094303 MONJFEAB_00017 20828 6 Skin 0.12 protein_coding start_lost HIGH 1A>G Met1?
M0094304 MONJFEAB_00017 21054 6 Skin 0.12 protein_coding missense_variant MODERATE 227A>G Gln76Arg
M0094305 MONJFEAB_00017 21132 3 Skin 0.06 protein_coding missense_variant MODERATE 305T>C Val102Ala
M0094306 MONJFEAB_00017 21184 3 Skin 0.06 protein_coding synonymous_variant LOW 357G>A Thr119Thr
M0094307 MONJFEAB_00017 21190 3 Skin 0.06 protein_coding synonymous_variant LOW 363C>T Tyr121Tyr
M0094308 MONJFEAB_00017 21205 3 Skin 0.06 protein_coding synonymous_variant LOW 378C>T Asp126Asp
M0094309 MONJFEAB_00017 21206 5 Skin 0.10 protein_coding missense_variant MODERATE 379G>A Ala127Thr
M0094310 MONJFEAB_00017 21232 3 Skin 0.06 protein_coding synonymous_variant LOW 405T>C Asp135Asp
M0094311 MONJFEAB_00017 21250 3 Skin 0.06 protein_coding synonymous_variant LOW 423C>T Thr141Thr
M0094312 MONJFEAB_00017 21253 3 Skin 0.06 protein_coding synonymous_variant LOW 426G>C Leu142Leu
M0094313 MONJFEAB_00017 21259 3 Skin 0.06 protein_coding synonymous_variant LOW 432G>A Lys144Lys
M0094314 MONJFEAB_00017 21262 3 Skin 0.06 protein_coding synonymous_variant LOW 435C>G Thr145Thr
M0094315 MONJFEAB_00017 21283 3 Skin 0.06 protein_coding synonymous_variant LOW 456C>G Leu152Leu
M0094316 MONJFEAB_00017 21295 3 Skin 0.06 protein_coding synonymous_variant LOW 468G>A Val156Val
M0094317 MONJFEAB_00017 21310 4 Skin 0.08 protein_coding synonymous_variant LOW 483T>C His161His
M0094318 MONJFEAB_00017 21376 3 Skin 0.06 protein_coding synonymous_variant LOW 549A>G Val183Val
M0094319 MONJFEAB_00017 21566 11 Skin 0.21 protein_coding missense_variant MODERATE 739A>G Lys247Glu
M0094320 MONJFEAB_00018 21874 11 Skin 0.21 protein_coding missense_variant MODERATE 214T>G Ser72Ala
M0094321 MONJFEAB_00019 22081 11 Skin 0.21 protein_coding missense_variant MODERATE 122C>T Ala41Val
M0094322 MONJFEAB_00015 20028 3 Skin 0.06 protein_coding missense_variant MODERATE 2723A>G Gln908Arg
M0094323 MONJFEAB_00017 20968 5 Skin 0.10 protein_coding synonymous_variant LOW 141T>C Ala47Ala
M0094324 MONJFEAB_00017 21166 4 Skin 0.08 protein_coding missense_variant MODERATE 339G>C Glu113Asp
M0094325 MONJFEAB_00061 53554 5 Skin 0.10 protein_coding synonymous_variant LOW 579C>T His193His
M0094326 MONJFEAB_00061 54013 5 Skin 0.10 protein_coding synonymous_variant LOW 120A>G Glu40Glu
M0094327 MONJFEAB_00061 53067 4 Skin 0.08 protein_coding missense_variant MODERATE 1066A>C Ser356Arg
M0094328 MONJFEAB_00015 17820 4 Skin 0.08 protein_coding missense_variant MODERATE 515T>C Met172Thr
M0094329 MONJFEAB_00015 17893 4 Skin 0.08 protein_coding synonymous_variant LOW 588T>C Phe196Phe
M0094330 MONJFEAB_00023 25579 4 Skin 0.08 protein_coding missense_variant MODERATE 176G>A Arg59Lys
M0094331 MONJFEAB_00023 25663 4 Skin 0.08 protein_coding missense_variant MODERATE 260T>C Val87Ala
M0094332 MONJFEAB_00023 25861 4 Skin 0.08 protein_coding missense_variant MODERATE 458G>A Gly153Asp
M0094333 MONJFEAB_00023 26653 4 Skin 0.08 protein_coding missense_variant MODERATE 1250C>T Ser417Phe
M0094334 MONJFEAB_00020 22773 8 Skin 0.15 protein_coding missense_variant MODERATE 340G>A Gly114Ser
M0094335 MONJFEAB_00020 22774 8 Skin 0.15 protein_coding missense_variant MODERATE 341G>A Gly114Asp
M0094336 MONJFEAB_00015 19066 3 Skin 0.06 protein_coding synonymous_variant LOW 1761T>C Leu587Leu
M0094337 MONJFEAB_00074 64513 3 Skin 0.06 protein_coding synonymous_variant LOW 930C>T Ile310Ile
M0094338 MONJFEAB_00074 64519 3 Skin 0.06 protein_coding synonymous_variant LOW 924T>C Phe308Phe
M0094339 MONJFEAB_00074 64522 3 Skin 0.06 protein_coding synonymous_variant LOW 921C>T Arg307Arg
M0094340 MONJFEAB_00074 64525 3 Skin 0.06 protein_coding synonymous_variant LOW 918T>C Ser306Ser
M0094341 MONJFEAB_00074 64931 4 Skin 0.08 protein_coding missense_variant MODERATE 512G>A Arg171Gln
M0094342 MONJFEAB_00074 65293 4 Skin 0.08 protein_coding synonymous_variant LOW 150G>A Ser50Ser
M0094343 MONJFEAB_00068 65485 4 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -4733G>A None
M0094344 MONJFEAB_00011 13936 3 Skin 0.06 protein_coding missense_variant MODERATE 965T>C Val322Ala
M0094345 MONJFEAB_00011 13979 3 Skin 0.06 protein_coding missense_variant MODERATE 922T>G Leu308Val
M0094346 MONJFEAB_00011 13995 3 Skin 0.06 protein_coding synonymous_variant LOW 906A>G Val302Val
M0094347 MONJFEAB_00011 14061 3 Skin 0.06 protein_coding synonymous_variant LOW 840T>C Phe280Phe
M0094348 MONJFEAB_00011 14741 3 Skin 0.06 protein_coding missense_variant MODERATE 160A>C Thr54Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term