Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C561
  Reference Plasmid   NZ_CP031209.1
  Reference Plasmid Size   43771
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0168552 GJGBFDPJ_00039 34291 3 Gut 0.75 protein_coding synonymous_variant LOW 553T>C Leu185Leu
M0168553 GJGBFDPJ_00039 34967 3 Gut 0.75 protein_coding splice_region_variant&stop_retained_variant LOW 1229A>G Ter410Ter
M0168554 GJGBFDPJ_00040 35162 3 Gut 0.75 protein_coding synonymous_variant LOW 192C>T Asp64Asp
M0168555 GJGBFDPJ_00040 35165 3 Gut 0.75 protein_coding synonymous_variant LOW 195C>T Tyr65Tyr
M0168556 GJGBFDPJ_00040 35168 3 Gut 0.75 protein_coding synonymous_variant LOW 198C>T Asn66Asn
M0168557 GJGBFDPJ_00040 35228 3 Gut 0.75 protein_coding synonymous_variant LOW 258G>A Gln86Gln






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
GJGBFDPJ_00026 QCZ56711.1|GH25 100 1.92e-186 1 250 1 1
GJGBFDPJ_00029 AGL62902.2|GH36 99.1 4.08e-158 1 222 1 0.7184
GJGBFDPJ_00030 QCZ47262.1|CE4 100 8.75e-219 1 295 0.9736 1
GJGBFDPJ_00031 QCZ47264.1|GT2 100 8.33e-221 1 312 1 0.7685





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
GJGBFDPJ_00020 1.E.65.1.5 74.7 3e-30 1 87 1.0000 1.0000 1 Channels/Pores 1.E Holins 1.E.65 The Firmicute Prophage XhlA Holin (XhlA) Family