Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C571
  Reference Plasmid   NZ_CP033227.1
  Reference Plasmid Size   505328
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0095584 BLOCMBBC_00327 316062 3 Skin 0.05 protein_coding synonymous_variant LOW 552G>A Gly184Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
BLOCMBBC_00094 Gold (Au), Methylene Blue [class: Thiazinium], Crystal Violet [class: Triarylmethane] 77.8 0 1 1047 0.9896 0.9924 experiment
BLOCMBBC_00138 Copper (Cu), Gold (Au) 74.3 1.8e-306 80 823 0.8900 0.9764 experiment
BLOCMBBC_00094 Gold (Au), Methylene Blue [class: Thiazinium], Crystal Violet [class: Triarylmethane] 79 0 1 1048 0.9905 0.9905 prediction
BLOCMBBC_00138 Copper (Cu), Gold (Au) 75.4 0 8 823 0.9761 0.9796 prediction
BLOCMBBC_00194 Copper (Cu) 100 2.8e-63 1 125 1.0000 1.0000 prediction
BLOCMBBC_00227 Mercury (Hg) 100 6.8e-83 1 159 1.0000 1.0000 prediction
BLOCMBBC_00325 Chromium (Cr) 77.3 1e-98 27 242 0.8889 0.9643 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism
BLOCMBBC_00094 ARO:3000790 77.8 0 1 1047 0.9896 0.9924 monobactam resistance-nodulation-cell division (RND) antibiotic efflux pump antibiotic efflux
BLOCMBBC_00340 ARO:3004361 100 8.08e-201 1 287 1.0000 1.0000 sulfonamide antibiotic sulfonamide resistant sul antibiotic target replacement






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
BLOCMBBC_00339 PHI:9804 int 100 4e-14 1 37 0.1098 1.0000 rodents gastroenteritis integrase reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
BLOCMBBC_00020 AYO75456.1|GH23 100 1.47e-147 1 209 1 1
BLOCMBBC_00515 AYO75858.1|GH130 100 0 1 432 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
BLOCMBBC_00094 2.A.6.2.25 77.8 0 1 1047 0.9896 2.0815 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.6 The Resistance-Nodulation-Cell Division (RND) Superfamily
BLOCMBBC_00138 3.A.3.5.20 74.3 6.7e-305 80 823 0.8900 0.9764 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.3 The P-type ATPase (P-ATPase) Superfamily
BLOCMBBC_00192 3.A.3.5.39 71.8 4.89999999999989e-311 85 857 0.9020 0.9607 3 Primary Active Transporters 3.A P-P-bond-hydrolysis-driven transporters 3.A.3 The P-type ATPase (P-ATPase) Superfamily