Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C573
  Reference Plasmid   NZ_CP033248.1
  Reference Plasmid Size   882389
  Reference Plasmid GC Content   0.29
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0168789 EGEHHDEH_00328 381265 3 Gut 0.19 protein_coding synonymous_variant LOW 435G>A Arg145Arg
M0168790 EGEHHDEH_00328 381269 3 Gut 0.19 protein_coding missense_variant MODERATE 439C>A His147Asn
M0168791 EGEHHDEH_00328 381288 3 Gut 0.19 protein_coding missense_variant MODERATE 458A>G Asn153Ser
M0168792 EGEHHDEH_00328 381289 3 Gut 0.19 protein_coding synonymous_variant LOW 459T>C Asn153Asn
M0168793 EGEHHDEH_00330 382302 3 Gut 0.19 protein_coding missense_variant MODERATE 11T>C Leu4Ser
M0168794 EGEHHDEH_00331 383581 3 Gut 0.19 protein_coding missense_variant MODERATE 355T>G Ser119Ala
M0168795 EGEHHDEH_00333 387174 3 Gut 0.19 protein_coding missense_variant MODERATE 583C>G His195Asp
M0168796 EGEHHDEH_00336 390309 3 Gut 0.19 protein_coding missense_variant MODERATE 562A>G Ile188Val






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
EGEHHDEH_00078 QGH20124.1|GH31 100 0 1 781 1 1
EGEHHDEH_00079 QGH24160.1|GH3 100 0 1 707 1 1
EGEHHDEH_00080 QGH20126.1|GH95 100 0 1 799 1 1
EGEHHDEH_00091 QGH20134.1|GT4 100 0 1 622 1 1
EGEHHDEH_00093 QGH20136.1|GT2|GT4 100 0 1 609 1 1
EGEHHDEH_00098 QGH24176.1|GH12 100 2.85e-186 1 246 1 1
EGEHHDEH_00099 QGH20142.1|GH2 100 0 1 930 1 1
EGEHHDEH_00104 QGH20147.1|GH74 100 0 1 777 1 1
EGEHHDEH_00105 QJU46751.1|GH13_44 100 0 1 515 1 1
EGEHHDEH_00108 QGH20151.1|GH1 100 0 2 470 0.9979 1
EGEHHDEH_00135 QGH24211.1|GH32 100 0 1 491 1 1
EGEHHDEH_00231 QGH20263.1|GH38 100 0 1 870 1 1
EGEHHDEH_00240 QGH20271.1|GH4 100 0 1 441 1 1
EGEHHDEH_00267 QGH24331.1|CE4 100 1.68e-186 1 291 1 0.9209
EGEHHDEH_00332 QCJ08657.1|GH13_29 100 0 1 552 1 1
EGEHHDEH_00419 AXB86842.1|GH170 100 1.04e-268 1 360 1 1
EGEHHDEH_00424 ANF16086.1|GH4 100 1.14999999850097e-315 1 436 1 1
EGEHHDEH_00518 QGH20513.1|GH1 100 0 1 479 1 1
EGEHHDEH_00520 QGH24549.1|CBM4|GH16_3 100 0 1 1251 1 1
EGEHHDEH_00574 QGH20562.1|CE4 100 3.19e-186 1 252 1 1
EGEHHDEH_00605 QGH24633.1|GH53 100 4.36e-265 1 341 1 1
EGEHHDEH_00606 QGH24634.1|GH42 100 0 1 687 1 1
EGEHHDEH_00629 AXB87048.1|GH4 100 0 1 444 1 1
EGEHHDEH_00659 QGH24680.1|GH24 100 0 1 547 1 1
EGEHHDEH_00756 QUF85207.1|CE8|PL9_1 98.4 0 1 1038 1 0.7616





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
EGEHHDEH_00045 4.A.6.1.6 72.9 1e-136 1 325 1.0000 1.0000 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family
EGEHHDEH_00046 4.A.6.1.6 76 1.1e-107 1 268 1.0000 0.8364 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family
EGEHHDEH_00047 4.A.6.1.15 75.9 1.7e-136 1 303 1.0000 0.9439 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family