Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C579
  Reference Plasmid   NZ_CP034070.1
  Reference Plasmid Size   2504
  Reference Plasmid GC Content   0.45
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0168866 KKLHHIDE_00001 378 9 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -58A>G None
M0168867 KKLHHIDE_00001 392 9 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -44G>T None
M0168868 KKLHHIDE_00001 416 9 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -20C>A None
M0168869 KKLHHIDE_00001 540 9 Gut 0.56 protein_coding missense_variant MODERATE 105G>A Met35Ile
M0168870 KKLHHIDE_00001 718 9 Gut 0.56 protein_coding missense_variant MODERATE 283A>C Ile95Leu
M0168871 KKLHHIDE_00001 967 9 Gut 0.56 protein_coding missense_variant MODERATE 532T>C Tyr178His
M0168872 KKLHHIDE_00001 1157 9 Gut 0.56 protein_coding missense_variant MODERATE 722A>G Lys241Arg
M0168873 KKLHHIDE_00003 1234 9 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -762A>G None
M0168874 KKLHHIDE_00003 1241 9 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -755T>G None
M0168875 KKLHHIDE_00003 1295 9 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -701G>T None
M0168876 KKLHHIDE_00003 1324 9 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -672A>T None
M0168877 KKLHHIDE_00003 1344 9 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -652C>G None
M0168878 KKLHHIDE_00003 1359 9 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -637T>A None
M0168879 KKLHHIDE_00003 1366 9 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -630A>G None
M0168880 KKLHHIDE_00003 1378 9 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -618C>T None
M0168881 KKLHHIDE_00002 1470 9 Gut 0.56 protein_coding missense_variant MODERATE 241A>G Ile81Val
M0168882 KKLHHIDE_00002 1531 9 Gut 0.56 protein_coding synonymous_variant LOW 180G>A Val60Val
M0168883 KKLHHIDE_00002 1558 9 Gut 0.56 protein_coding missense_variant MODERATE 153C>A Asn51Lys
M0168884 KKLHHIDE_00002 1591 9 Gut 0.56 protein_coding synonymous_variant LOW 120T>C Ser40Ser
M0168885 KKLHHIDE_00002 1735 10 Gut 0.63 protein_coding upstream_gene_variant MODIFIER -25C>A None
M0168886 KKLHHIDE_00002 1748 10 Gut 0.63 protein_coding upstream_gene_variant MODIFIER -38C>T None
M0168887 KKLHHIDE_00002 1897 9 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -187A>T None
M0168888 KKLHHIDE_00002 1990 9 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -280T>C None
M0168889 KKLHHIDE_00002 1991 9 Gut 0.56 protein_coding upstream_gene_variant MODIFIER -281C>T None
M0168890 KKLHHIDE_00003 2014 9 Gut 0.56 protein_coding missense_variant MODERATE 19A>G Thr7Ala
M0168891 KKLHHIDE_00003 2031 9 Gut 0.56 protein_coding synonymous_variant LOW 36G>A Ala12Ala
M0168892 KKLHHIDE_00003 2049 9 Gut 0.56 protein_coding synonymous_variant LOW 54G>A Gln18Gln






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term