Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C580
  Reference Plasmid   NZ_CP034114.1
  Reference Plasmid Size   11218
  Reference Plasmid GC Content   0.30
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0095594 ONKFFBKI_00001 1494 11 Skin 0.31 protein_coding synonymous_variant LOW 652T>C Leu218Leu
M0095595 ONKFFBKI_00001 6377 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -4232G>A None
M0095596 ONKFFBKI_00001 6384 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -4239C>T None
M0095597 ONKFFBKI_00001 6386 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -4241C>T None
M0095598 ONKFFBKI_00007 6548 4 Skin 0.11 protein_coding missense_variant MODERATE 98A>G Asn33Ser
M0095599 ONKFFBKI_00001 6903 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -4758G>A None
M0095600 ONKFFBKI_00001 6950 5 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -4805T>C None
M0095601 ONKFFBKI_00008 7193 5 Skin 0.14 protein_coding missense_variant MODERATE 230T>C Ile77Thr
M0095602 ONKFFBKI_00008 7291 5 Skin 0.14 protein_coding missense_variant MODERATE 328T>C Tyr110His
M0095603 ONKFFBKI_00009 7974 8 Skin 0.23 protein_coding synonymous_variant LOW 525C>T Ser175Ser
M0095604 ONKFFBKI_00009 8244 4 Skin 0.11 protein_coding synonymous_variant LOW 795A>C Ile265Ile
M0095605 ONKFFBKI_00009 8629 9 Skin 0.26 protein_coding missense_variant MODERATE 1180C>A Arg394Ser
M0095606 ONKFFBKI_00009 9167 8 Skin 0.23 protein_coding missense_variant MODERATE 1718C>T Thr573Ile
M0095607 ONKFFBKI_00009 9465 8 Skin 0.23 protein_coding synonymous_variant LOW 2016T>C Asn672Asn
M0095608 ONKFFBKI_00010 9557 3 Skin 0.09 protein_coding synonymous_variant LOW 63C>T Asn21Asn
M0095609 ONKFFBKI_00010 9989 5 Skin 0.14 protein_coding synonymous_variant LOW 495A>G Glu165Glu
M0095610 ONKFFBKI_00001 4100 7 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -1955A>C None
M0095611 ONKFFBKI_00009 8826 5 Skin 0.14 protein_coding synonymous_variant LOW 1377G>A Lys459Lys
M0095612 ONKFFBKI_00009 8897 3 Skin 0.09 protein_coding missense_variant MODERATE 1448A>G Asn483Ser
M0095613 ONKFFBKI_00009 8477 4 Skin 0.11 protein_coding missense_variant MODERATE 1028A>T Glu343Val
M0095614 ONKFFBKI_00009 8606 4 Skin 0.11 protein_coding missense_variant MODERATE 1157T>A Ile386Lys
M0095615 ONKFFBKI_00010 10067 5 Skin 0.14 protein_coding synonymous_variant LOW 573C>T Ser191Ser
M0095616 ONKFFBKI_00005 5819 4 Skin 0.11 protein_coding missense_variant MODERATE 58A>T Ile20Phe
M0095617 ONKFFBKI_00005 5845 4 Skin 0.11 protein_coding missense_variant MODERATE 32G>A Cys11Tyr
M0095618 ONKFFBKI_00005 5847 4 Skin 0.11 protein_coding missense_variant MODERATE 30T>G Cys10Trp
M0095619 ONKFFBKI_00005 5873 4 Skin 0.11 protein_coding synonymous_variant LOW 4T>C Leu2Leu
M0095620 ONKFFBKI_00001 5939 4 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -3794A>G None
M0095621 ONKFFBKI_00001 5948 4 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -3803T>C None
M0095622 ONKFFBKI_00006 5964 4 Skin 0.11 protein_coding synonymous_variant LOW 12G>A Lys4Lys
M0095623 ONKFFBKI_00006 6180 3 Skin 0.09 protein_coding synonymous_variant LOW 228T>C Asn76Asn
M0095624 ONKFFBKI_00001 2180 3 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -35A>C None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term