Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C587
  Reference Plasmid   NZ_CP034950.1
  Reference Plasmid Size   37182
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0168951 AIDBCHHH_00022 25590 3 Gut 0.23 protein_coding upstream_gene_variant MODIFIER -4813T>G None
M0168952 AIDBCHHH_00035 32730 4 Gut 0.31 protein_coding synonymous_variant LOW 39A>G Leu13Leu
M0168953 AIDBCHHH_00035 32749 4 Gut 0.31 protein_coding missense_variant MODERATE 20C>T Thr7Ile
M0168954 AIDBCHHH_00037 33765 4 Gut 0.31 protein_coding missense_variant MODERATE 1484T>C Ile495Thr
M0168955 AIDBCHHH_00037 34037 4 Gut 0.31 protein_coding synonymous_variant LOW 1212A>G Glu404Glu
M0168956 AIDBCHHH_00037 34715 4 Gut 0.31 protein_coding synonymous_variant LOW 534C>T Tyr178Tyr
M0168957 AIDBCHHH_00038 35748 4 Gut 0.31 protein_coding synonymous_variant LOW 69A>G Leu23Leu
M0168958 AIDBCHHH_00038 35798 4 Gut 0.31 protein_coding missense_variant MODERATE 19A>G Ile7Val
M0168959 AIDBCHHH_00035 35819 4 Gut 0.31 protein_coding upstream_gene_variant MODIFIER -3051T>A None
M0168960 AIDBCHHH_00039 35968 4 Gut 0.31 protein_coding synonymous_variant LOW 735T>C Ile245Ile
M0168961 AIDBCHHH_00039 36199 4 Gut 0.31 protein_coding synonymous_variant LOW 504T>C Ile168Ile
M0168962 AIDBCHHH_00028 32084 3 Gut 0.23 protein_coding upstream_gene_variant MODIFIER -4722A>C None
M0168963 AIDBCHHH_00036 32788 3 Gut 0.23 protein_coding synonymous_variant LOW 783G>A Gly261Gly
M0168964 AIDBCHHH_00036 33148 3 Gut 0.23 protein_coding synonymous_variant LOW 423T>A Pro141Pro
M0168965 AIDBCHHH_00023 20940 5 Gut 0.38 protein_coding missense_variant MODERATE 1454A>G Asp485Gly
M0168966 AIDBCHHH_00023 21098 5 Gut 0.38 protein_coding synonymous_variant LOW 1296A>G Ala432Ala
M0168967 AIDBCHHH_00010 14560 3 Gut 0.23 protein_coding upstream_gene_variant MODIFIER -4455G>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
AIDBCHHH_00023 PHI:8586 mntH1 77.4 1.6e-222 17 530 0.9607 0.9737 moths nosocomial infection divalent metal cation transporter unaffected pathogenicity
AIDBCHHH_00033 PHI:5205 HMPREF0351_10118 (WxL locusC) 75 1.5e-174 1 392 0.9899 1.0000 rodents endocarditis involved in bile salt stress and endocarditis pathogenesis reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
AIDBCHHH_00026 AGL62902.2|GH36 92.6 2.63e-209 1 309 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term