Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C592
  Reference Plasmid   NZ_CP035465.1
  Reference Plasmid Size   8720
  Reference Plasmid GC Content   0.64
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0168982 DAIFFHCA_00001 2011 9 Gut 0.64 protein_coding upstream_gene_variant MODIFIER -673G>A None
M0168983 DAIFFHCA_00003 2562 9 Gut 0.64 protein_coding synonymous_variant LOW 150T>C Gly50Gly
M0168984 DAIFFHCA_00003 2566 9 Gut 0.64 protein_coding synonymous_variant LOW 154T>C Leu52Leu
M0168985 DAIFFHCA_00003 2581 9 Gut 0.64 protein_coding missense_variant MODERATE 169G>A Val57Ile
M0168986 DAIFFHCA_00003 2661 9 Gut 0.64 protein_coding synonymous_variant LOW 249C>T Asn83Asn
M0168987 DAIFFHCA_00003 2689 9 Gut 0.64 protein_coding missense_variant MODERATE 277A>G Thr93Ala
M0168988 DAIFFHCA_00003 2690 9 Gut 0.64 protein_coding missense_variant MODERATE 278C>T Thr93Met
M0168989 DAIFFHCA_00003 2691 9 Gut 0.64 protein_coding synonymous_variant LOW 279G>A Thr93Thr
M0168990 DAIFFHCA_00003 2692 9 Gut 0.64 protein_coding synonymous_variant LOW 280C>T Leu94Leu
M0168991 DAIFFHCA_00003 2694 9 Gut 0.64 protein_coding synonymous_variant LOW 282G>A Leu94Leu
M0168992 DAIFFHCA_00003 2760 9 Gut 0.64 protein_coding synonymous_variant LOW 348G>T Leu116Leu
M0168993 DAIFFHCA_00003 2853 9 Gut 0.64 protein_coding synonymous_variant LOW 441C>T Val147Val
M0168994 DAIFFHCA_00003 2874 9 Gut 0.64 protein_coding synonymous_variant LOW 462C>T Ile154Ile
M0168995 DAIFFHCA_00003 2877 9 Gut 0.64 protein_coding synonymous_variant LOW 465T>C Asp155Asp
M0168996 DAIFFHCA_00003 3264 9 Gut 0.64 protein_coding synonymous_variant LOW 852G>A Glu284Glu
M0168997 DAIFFHCA_00001 3807 8 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -2469A>G None
M0168998 DAIFFHCA_00001 3818 8 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -2480C>T None
M0168999 DAIFFHCA_00001 3872 10 Gut 0.71 protein_coding upstream_gene_variant MODIFIER -2534C>T None
M0169000 DAIFFHCA_00001 3983 8 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -2645A>G None
M0169001 DAIFFHCA_00001 3990 8 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -2652C>T None
M0169002 DAIFFHCA_00001 4005 8 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -2667C>T None
M0169003 DAIFFHCA_00001 4013 8 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -2675G>A None
M0169004 DAIFFHCA_00001 4035 8 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -2697C>A None
M0169005 DAIFFHCA_00001 4036 8 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -2698C>A None
M0169006 DAIFFHCA_00001 4037 8 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -2699T>C None
M0169007 DAIFFHCA_00001 4050 8 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -2712A>G None
M0169008 DAIFFHCA_00001 4057 8 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -2719T>C None
M0169009 DAIFFHCA_00001 4065 8 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -2727C>T None
M0169010 DAIFFHCA_00005 4081 8 Gut 0.57 protein_coding synonymous_variant LOW 237A>G Arg79Arg
M0169011 DAIFFHCA_00005 4083 8 Gut 0.57 protein_coding synonymous_variant LOW 235A>C Arg79Arg
M0169012 DAIFFHCA_00005 4124 9 Gut 0.64 protein_coding missense_variant MODERATE 194A>C Asn65Thr
M0169013 DAIFFHCA_00005 4129 9 Gut 0.64 protein_coding synonymous_variant LOW 189G>T Ala63Ala
M0169014 DAIFFHCA_00005 4213 12 Gut 0.86 protein_coding synonymous_variant LOW 105T>C Arg35Arg
M0169015 DAIFFHCA_00005 4216 9 Gut 0.64 protein_coding synonymous_variant LOW 102C>A Gly34Gly
M0169016 DAIFFHCA_00005 4221 9 Gut 0.64 protein_coding missense_variant MODERATE 97A>G Thr33Ala
M0169017 DAIFFHCA_00005 4294 9 Gut 0.64 protein_coding synonymous_variant LOW 24C>T Leu8Leu
M0169018 DAIFFHCA_00006 4329 9 Gut 0.64 protein_coding synonymous_variant LOW 585A>G Arg195Arg
M0169019 DAIFFHCA_00006 4335 9 Gut 0.64 protein_coding synonymous_variant LOW 579A>G Glu193Glu
M0169020 DAIFFHCA_00006 4407 9 Gut 0.64 protein_coding synonymous_variant LOW 507T>C Arg169Arg
M0169021 DAIFFHCA_00006 4676 9 Gut 0.64 protein_coding missense_variant MODERATE 238G>A Asp80Asn
M0169022 DAIFFHCA_00006 4723 9 Gut 0.64 protein_coding missense_variant MODERATE 191A>G Lys64Arg
M0169023 DAIFFHCA_00006 4770 9 Gut 0.64 protein_coding synonymous_variant LOW 144G>A Gln48Gln
M0169024 DAIFFHCA_00006 4773 9 Gut 0.64 protein_coding synonymous_variant LOW 141A>C Ala47Ala
M0169025 DAIFFHCA_00006 4800 12 Gut 0.86 protein_coding synonymous_variant LOW 114T>C Asp38Asp
M0169026 DAIFFHCA_00006 4897 9 Gut 0.64 protein_coding missense_variant MODERATE 17C>T Thr6Ile
M0169027 DAIFFHCA_00001 4923 9 Gut 0.64 protein_coding upstream_gene_variant MODIFIER -3585G>T None
M0169028 DAIFFHCA_00001 4924 9 Gut 0.64 protein_coding upstream_gene_variant MODIFIER -3586C>A None
M0169029 DAIFFHCA_00001 4927 9 Gut 0.64 protein_coding upstream_gene_variant MODIFIER -3589T>A None
M0169030 DAIFFHCA_00001 4963 9 Gut 0.64 protein_coding upstream_gene_variant MODIFIER -3625T>C None
M0169031 DAIFFHCA_00001 4986 9 Gut 0.64 protein_coding upstream_gene_variant MODIFIER -3648C>T None
M0169032 DAIFFHCA_00007 5002 12 Gut 0.86 protein_coding missense_variant MODERATE 3650A>G Glu1217Gly
M0169033 DAIFFHCA_00007 5061 9 Gut 0.64 protein_coding synonymous_variant LOW 3591A>G Ala1197Ala
M0169034 DAIFFHCA_00007 5161 9 Gut 0.64 protein_coding missense_variant MODERATE 3491A>G His1164Arg
M0169035 DAIFFHCA_00007 5170 11 Gut 0.79 protein_coding missense_variant MODERATE 3482T>C Val1161Ala
M0169036 DAIFFHCA_00007 5206 9 Gut 0.64 protein_coding missense_variant MODERATE 3446A>G Lys1149Arg
M0169037 DAIFFHCA_00007 5211 9 Gut 0.64 protein_coding synonymous_variant LOW 3441C>T Arg1147Arg
M0169038 DAIFFHCA_00007 5240 9 Gut 0.64 protein_coding missense_variant MODERATE 3412A>G Ile1138Val
M0169039 DAIFFHCA_00007 5276 9 Gut 0.64 protein_coding missense_variant MODERATE 3376A>G Lys1126Glu
M0169040 DAIFFHCA_00007 5687 9 Gut 0.64 protein_coding missense_variant MODERATE 2965A>G Thr989Ala
M0169041 DAIFFHCA_00007 5715 7 Gut 0.50 protein_coding synonymous_variant LOW 2937C>T Leu979Leu
M0169042 DAIFFHCA_00007 5788 9 Gut 0.64 protein_coding missense_variant MODERATE 2864A>G Asp955Gly
M0169043 DAIFFHCA_00007 5963 12 Gut 0.86 protein_coding missense_variant MODERATE 2689G>A Ala897Thr
M0169044 DAIFFHCA_00007 6144 11 Gut 0.79 protein_coding synonymous_variant LOW 2508T>C Gly836Gly
M0169045 DAIFFHCA_00007 6152 9 Gut 0.64 protein_coding missense_variant MODERATE 2500A>G Lys834Glu
M0169046 DAIFFHCA_00007 6159 9 Gut 0.64 protein_coding synonymous_variant LOW 2493A>G Leu831Leu
M0169047 DAIFFHCA_00007 6171 9 Gut 0.64 protein_coding synonymous_variant LOW 2481C>T Arg827Arg
M0169048 DAIFFHCA_00007 6219 9 Gut 0.64 protein_coding missense_variant MODERATE 2433T>G Asp811Glu
M0169049 DAIFFHCA_00007 6400 9 Gut 0.64 protein_coding missense_variant MODERATE 2252C>T Ser751Leu
M0169050 DAIFFHCA_00007 6469 9 Gut 0.64 protein_coding missense_variant MODERATE 2183A>C Glu728Ala
M0169051 DAIFFHCA_00007 6628 8 Gut 0.57 protein_coding missense_variant MODERATE 2024C>T Ala675Val
M0169052 DAIFFHCA_00007 6753 10 Gut 0.71 protein_coding synonymous_variant LOW 1899T>C Leu633Leu
M0169053 DAIFFHCA_00007 6788 8 Gut 0.57 protein_coding missense_variant MODERATE 1864G>A Ala622Thr
M0169054 DAIFFHCA_00007 6810 8 Gut 0.57 protein_coding synonymous_variant LOW 1842C>A Gly614Gly
M0169055 DAIFFHCA_00007 6862 10 Gut 0.71 protein_coding missense_variant MODERATE 1790G>A Gly597Glu
M0169056 DAIFFHCA_00007 6923 10 Gut 0.71 protein_coding synonymous_variant LOW 1729C>T Leu577Leu
M0169057 DAIFFHCA_00007 7185 10 Gut 0.71 protein_coding synonymous_variant LOW 1467T>G Thr489Thr
M0169058 DAIFFHCA_00007 7191 10 Gut 0.71 protein_coding synonymous_variant LOW 1461A>G Arg487Arg
M0169059 DAIFFHCA_00007 7221 8 Gut 0.57 protein_coding synonymous_variant LOW 1431C>A Gly477Gly
M0169060 DAIFFHCA_00007 7354 8 Gut 0.57 protein_coding missense_variant MODERATE 1298G>A Arg433His
M0169061 DAIFFHCA_00007 7356 8 Gut 0.57 protein_coding synonymous_variant LOW 1296C>T Asp432Asp
M0169062 DAIFFHCA_00007 7409 8 Gut 0.57 protein_coding missense_variant MODERATE 1243T>A Ser415Thr
M0169063 DAIFFHCA_00007 7413 8 Gut 0.57 protein_coding synonymous_variant LOW 1239G>A Gly413Gly
M0169064 DAIFFHCA_00007 7421 8 Gut 0.57 protein_coding missense_variant MODERATE 1231G>A Ala411Thr
M0169065 DAIFFHCA_00007 7692 8 Gut 0.57 protein_coding synonymous_variant LOW 960A>C Gly320Gly
M0169066 DAIFFHCA_00007 7825 8 Gut 0.57 protein_coding missense_variant MODERATE 827T>C Val276Ala
M0169067 DAIFFHCA_00007 7877 8 Gut 0.57 protein_coding synonymous_variant LOW 775C>A Arg259Arg
M0169068 DAIFFHCA_00007 7910 10 Gut 0.71 protein_coding missense_variant MODERATE 742C>A Gln248Lys
M0169069 DAIFFHCA_00007 8004 7 Gut 0.50 protein_coding synonymous_variant LOW 648T>G Arg216Arg
M0169070 DAIFFHCA_00007 8060 7 Gut 0.50 protein_coding missense_variant MODERATE 592G>A Gly198Arg
M0169071 DAIFFHCA_00007 8175 7 Gut 0.50 protein_coding synonymous_variant LOW 477G>A Gly159Gly
M0169072 DAIFFHCA_00007 8202 8 Gut 0.57 protein_coding synonymous_variant LOW 450A>G Ala150Ala
M0169073 DAIFFHCA_00007 8241 9 Gut 0.64 protein_coding missense_variant MODERATE 411T>G Asp137Glu
M0169074 DAIFFHCA_00007 8277 9 Gut 0.64 protein_coding missense_variant MODERATE 375T>G Asp125Glu
M0169075 DAIFFHCA_00007 8292 8 Gut 0.57 protein_coding synonymous_variant LOW 360T>C Asp120Asp
M0169076 DAIFFHCA_00007 8302 8 Gut 0.57 protein_coding missense_variant MODERATE 350A>G Gln117Arg
M0169077 DAIFFHCA_00007 8306 8 Gut 0.57 protein_coding missense_variant MODERATE 346T>C Cys116Arg
M0169078 DAIFFHCA_00007 8308 8 Gut 0.57 protein_coding missense_variant MODERATE 344C>T Pro115Leu
M0169079 DAIFFHCA_00007 8309 8 Gut 0.57 protein_coding missense_variant MODERATE 343C>A Pro115Thr
M0169080 DAIFFHCA_00007 8310 8 Gut 0.57 protein_coding synonymous_variant LOW 342T>C Gly114Gly
M0169081 DAIFFHCA_00007 8318 8 Gut 0.57 protein_coding missense_variant MODERATE 334A>G Thr112Ala
M0169082 DAIFFHCA_00007 8346 9 Gut 0.64 protein_coding synonymous_variant LOW 306A>G Glu102Glu
M0169083 DAIFFHCA_00007 8490 8 Gut 0.57 protein_coding synonymous_variant LOW 162C>T Thr54Thr
M0169084 DAIFFHCA_00007 8631 9 Gut 0.64 protein_coding synonymous_variant LOW 21C>T His7His
M0169085 DAIFFHCA_00004 8679 8 Gut 0.57 protein_coding upstream_gene_variant MODIFIER -4951G>A None
M0169086 DAIFFHCA_00007 4997 3 Gut 0.21 protein_coding missense_variant MODERATE 3655G>C Gly1219Arg
M0169087 DAIFFHCA_00007 5049 3 Gut 0.21 protein_coding synonymous_variant LOW 3603G>A Gln1201Gln
M0169088 DAIFFHCA_00007 5082 3 Gut 0.21 protein_coding missense_variant MODERATE 3570G>C Gln1190His
M0169089 DAIFFHCA_00007 5108 3 Gut 0.21 protein_coding missense_variant MODERATE 3544C>T His1182Tyr
M0169090 DAIFFHCA_00007 5146 3 Gut 0.21 protein_coding missense_variant MODERATE 3506C>T Ala1169Val
M0169091 DAIFFHCA_00007 5207 3 Gut 0.21 protein_coding missense_variant MODERATE 3445A>G Lys1149Glu
M0169092 DAIFFHCA_00007 5437 3 Gut 0.21 protein_coding missense_variant MODERATE 3215A>G Asp1072Gly
M0169093 DAIFFHCA_00007 5440 3 Gut 0.21 protein_coding missense_variant MODERATE 3212G>A Arg1071His
M0169094 DAIFFHCA_00007 5441 3 Gut 0.21 protein_coding missense_variant MODERATE 3211C>A Arg1071Ser
M0169095 DAIFFHCA_00007 5539 3 Gut 0.21 protein_coding missense_variant MODERATE 3113A>G His1038Arg
M0169096 DAIFFHCA_00007 5540 3 Gut 0.21 protein_coding missense_variant MODERATE 3112C>G His1038Asp
M0169097 DAIFFHCA_00007 5547 3 Gut 0.21 protein_coding missense_variant MODERATE 3105C>G Asp1035Glu
M0169098 DAIFFHCA_00007 5635 3 Gut 0.21 protein_coding missense_variant MODERATE 3017A>G Asp1006Gly
M0169099 DAIFFHCA_00007 5649 3 Gut 0.21 protein_coding missense_variant MODERATE 3003T>G His1001Gln
M0169100 DAIFFHCA_00007 5985 3 Gut 0.21 protein_coding synonymous_variant LOW 2667C>A Arg889Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term