Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C613
  Reference Plasmid   NZ_CP036540.1
  Reference Plasmid Size   85671
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0169800 CBFCKNED_00004 7026 3 Gut 0.38 protein_coding missense_variant MODERATE 1027T>G Tyr343Asp
M0169801 CBFCKNED_00004 7828 3 Gut 0.38 protein_coding synonymous_variant LOW 225T>C Asn75Asn
M0169802 CBFCKNED_00074 80510 4 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4676C>A None
M0169803 CBFCKNED_00074 80579 4 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4745T>C None
M0169804 CBFCKNED_00074 80749 4 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -4915A>G None
M0169805 CBFCKNED_00080 81201 4 Gut 0.50 protein_coding missense_variant MODERATE 81A>G Ile27Met
M0169806 CBFCKNED_00081 81911 4 Gut 0.50 protein_coding synonymous_variant LOW 996G>A Glu332Glu
M0169807 CBFCKNED_00081 81920 4 Gut 0.50 protein_coding synonymous_variant LOW 987A>G Gly329Gly
M0169808 CBFCKNED_00081 82703 4 Gut 0.50 protein_coding synonymous_variant LOW 204A>G Lys68Lys
M0169809 CBFCKNED_00081 82709 4 Gut 0.50 protein_coding synonymous_variant LOW 198T>C Phe66Phe
M0169810 CBFCKNED_00081 82712 4 Gut 0.50 protein_coding synonymous_variant LOW 195T>C Ser65Ser
M0169811 CBFCKNED_00081 82721 4 Gut 0.50 protein_coding missense_variant MODERATE 186A>C Glu62Asp
M0169812 CBFCKNED_00081 82733 4 Gut 0.50 protein_coding synonymous_variant LOW 174C>T Tyr58Tyr
M0169813 CBFCKNED_00081 82742 4 Gut 0.50 protein_coding synonymous_variant LOW 165A>G Lys55Lys
M0169814 CBFCKNED_00081 82754 4 Gut 0.50 protein_coding synonymous_variant LOW 153A>G Glu51Glu
M0169815 CBFCKNED_00081 82759 4 Gut 0.50 protein_coding missense_variant MODERATE 148T>G Ser50Ala
M0169816 CBFCKNED_00079 82971 4 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -2638A>G None
M0169817 CBFCKNED_00079 83375 4 Gut 0.50 protein_coding upstream_gene_variant MODIFIER -3042T>C None
M0169818 CBFCKNED_00082 83551 4 Gut 0.50 protein_coding missense_variant MODERATE 1567C>G Pro523Ala
M0169819 CBFCKNED_00082 83595 4 Gut 0.50 protein_coding missense_variant MODERATE 1523T>C Ile508Thr
M0169820 CBFCKNED_00082 83601 4 Gut 0.50 protein_coding missense_variant MODERATE 1517A>G Asn506Ser
M0169821 CBFCKNED_00082 83960 3 Gut 0.38 protein_coding missense_variant MODERATE 1158C>A Asp386Glu
M0169822 CBFCKNED_00082 85060 3 Gut 0.38 protein_coding missense_variant MODERATE 58T>C Phe20Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term