Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C617
  Reference Plasmid   NZ_CP036554.1
  Reference Plasmid Size   6129
  Reference Plasmid GC Content   0.42
  Reference Plasmid Mobility Type   mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0169833 FAKONDNL_00001 132 3 Gut 0.38 protein_coding synonymous_variant LOW 132G>A Glu44Glu
M0169834 FAKONDNL_00001 183 3 Gut 0.38 protein_coding synonymous_variant LOW 183T>C Asn61Asn
M0169835 FAKONDNL_00001 186 3 Gut 0.38 protein_coding synonymous_variant LOW 186T>C Asn62Asn
M0169836 FAKONDNL_00001 615 3 Gut 0.38 protein_coding synonymous_variant LOW 615A>C Thr205Thr
M0169837 FAKONDNL_00001 685 4 Gut 0.50 protein_coding missense_variant MODERATE 685A>G Ser229Gly
M0169838 FAKONDNL_00002 759 4 Gut 0.50 protein_coding missense_variant MODERATE 8T>C Ile3Thr
M0169839 FAKONDNL_00001 770 3 Gut 0.38 protein_coding missense_variant MODERATE 770T>C Leu257Pro
M0169840 FAKONDNL_00003 1587 3 Gut 0.38 protein_coding synonymous_variant LOW 417A>G Gly139Gly
M0169841 FAKONDNL_00004 2216 3 Gut 0.38 protein_coding synonymous_variant LOW 138A>G Gly46Gly
M0169842 FAKONDNL_00005 2805 3 Gut 0.38 protein_coding synonymous_variant LOW 138A>C Gly46Gly
M0169843 FAKONDNL_00006 3683 5 Gut 0.63 protein_coding synonymous_variant LOW 267G>T Leu89Leu
M0169844 FAKONDNL_00006 3932 5 Gut 0.63 protein_coding synonymous_variant LOW 18G>A Pro6Pro
M0169845 FAKONDNL_00007 4035 5 Gut 0.63 protein_coding synonymous_variant LOW 378T>C Leu126Leu
M0169846 FAKONDNL_00007 4043 5 Gut 0.63 protein_coding missense_variant MODERATE 370A>G Asn124Asp
M0169847 FAKONDNL_00007 4104 5 Gut 0.63 protein_coding synonymous_variant LOW 309T>C Tyr103Tyr
M0169848 FAKONDNL_00007 4185 4 Gut 0.50 protein_coding synonymous_variant LOW 228C>T Phe76Phe
M0169849 FAKONDNL_00007 4191 5 Gut 0.63 protein_coding synonymous_variant LOW 222T>G Val74Val
M0169850 FAKONDNL_00003 5674 3 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -3671G>C None
M0169851 FAKONDNL_00006 3118 3 Gut 0.38 protein_coding missense_variant MODERATE 832A>G Ile278Val
M0169852 FAKONDNL_00006 3209 4 Gut 0.50 protein_coding synonymous_variant LOW 741G>A Gln247Gln
M0169853 FAKONDNL_00006 3302 4 Gut 0.50 protein_coding synonymous_variant LOW 648C>T Val216Val
M0169854 FAKONDNL_00006 3386 4 Gut 0.50 protein_coding synonymous_variant LOW 564G>A Lys188Lys
M0169855 FAKONDNL_00006 3440 4 Gut 0.50 protein_coding synonymous_variant LOW 510T>C Phe170Phe
M0169856 FAKONDNL_00006 3451 4 Gut 0.50 protein_coding missense_variant MODERATE 499A>C Lys167Gln
M0169857 FAKONDNL_00006 3908 3 Gut 0.38 protein_coding synonymous_variant LOW 42C>T Tyr14Tyr
M0169858 FAKONDNL_00007 4064 3 Gut 0.38 protein_coding missense_variant MODERATE 349A>G Asn117Asp
M0169859 FAKONDNL_00007 4095 3 Gut 0.38 protein_coding synonymous_variant LOW 318C>A Gly106Gly
M0169860 FAKONDNL_00007 4098 3 Gut 0.38 protein_coding synonymous_variant LOW 315C>T His105His
M0169861 FAKONDNL_00007 4119 4 Gut 0.50 protein_coding synonymous_variant LOW 294C>T Cys98Cys
M0169862 FAKONDNL_00007 4149 3 Gut 0.38 protein_coding synonymous_variant LOW 264C>T Asn88Asn
M0169863 FAKONDNL_00007 4152 3 Gut 0.38 protein_coding synonymous_variant LOW 261G>A Val87Val
M0169864 FAKONDNL_00007 4197 3 Gut 0.38 protein_coding synonymous_variant LOW 216T>C Ala72Ala
M0169865 FAKONDNL_00007 4206 3 Gut 0.38 protein_coding synonymous_variant LOW 207C>A Leu69Leu
M0169866 FAKONDNL_00003 4552 3 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -2549T>C None
M0169867 FAKONDNL_00003 4564 3 Gut 0.38 protein_coding upstream_gene_variant MODIFIER -2561G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term