Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C632
  Reference Plasmid   NZ_CP039706.1
  Reference Plasmid Size   769292
  Reference Plasmid GC Content   0.28
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0170057 IEMEALAB_00583 685313 3 Gut 0.07 protein_coding upstream_gene_variant MODIFIER -4915G>A None
M0170058 IEMEALAB_00590 685753 3 Gut 0.07 protein_coding synonymous_variant LOW 864T>G Leu288Leu
M0170059 IEMEALAB_00590 686209 3 Gut 0.07 protein_coding synonymous_variant LOW 408A>G Val136Val
M0170060 IEMEALAB_00590 686499 3 Gut 0.07 protein_coding missense_variant MODERATE 118G>A Ala40Thr
M0170061 IEMEALAB_00591 686713 3 Gut 0.07 protein_coding synonymous_variant LOW 1194T>C Asp398Asp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
IEMEALAB_00057 QCJ08221.1|GH1 100 0 1 479 1 1
IEMEALAB_00059 QJU46465.1|CBM4|GH16_3 100 0 1 1231 1 1
IEMEALAB_00108 QJU46514.1|CE4 100 1.11e-186 1 252 1 1
IEMEALAB_00134 QJU46536.1|GH53 100 4.36e-265 1 341 1 1
IEMEALAB_00135 UZT08687.1|GH53 100 1.18e-250 1 326 1 1
IEMEALAB_00137 AOR96158.1|GH42 100 0 1 687 1 1
IEMEALAB_00159 APF21054.1|GH4 100 0 1 444 1 1
IEMEALAB_00205 QCJ08353.1|CE8|PL9_1 100 0 1 1365 1 1
IEMEALAB_00344 BBK78922.1|GH31 100 0 1 781 1 1
IEMEALAB_00345 QCJ08484.1|GH3 100 0 1 707 1 1
IEMEALAB_00346 QMW92850.1|GH95 100 0 1 799 1 1
IEMEALAB_00358 QCJ08496.1|GT4 100 0 1 622 1 1
IEMEALAB_00360 QJU46739.1|GT2|GT4 100 0 1 609 1 1
IEMEALAB_00365 QJU46744.1|GH12 100 1.16e-187 1 250 1 1
IEMEALAB_00366 QJU46745.1|GH2 100 0 1 930 1 1
IEMEALAB_00371 QJU46750.1|GH74 100 0 1 778 1 1
IEMEALAB_00372 QJU46751.1|GH13_44 100 0 1 515 1 1
IEMEALAB_00429 AXB86673.1|GH38 100 0 1 870 1 1
IEMEALAB_00440 AXB86683.1|GH4 100 0 1 441 1 1
IEMEALAB_00466 QCJ08596.1|CE4 100 6.84e-204 1 316 1 1
IEMEALAB_00472 AXB86712.1|GT1 100 0 1 439 1 1
IEMEALAB_00533 QCJ08657.1|GH13_29 100 0 1 552 1 1
IEMEALAB_00614 AXB86842.1|GH170 100 1.04e-268 1 360 1 1
IEMEALAB_00619 ANF16086.1|GH4 100 1.14999999850097e-315 1 436 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
IEMEALAB_00309 4.A.6.1.6 72.9 1e-136 1 325 1.0000 1.0000 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family
IEMEALAB_00310 4.A.6.1.6 76 1.1e-107 1 268 1.0000 0.8364 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family
IEMEALAB_00311 4.A.6.1.15 75.9 1.7e-136 1 303 1.0000 0.9439 4 Group Translocators 4.A Phosphotransfer-driven Group Translocators (PTS) 4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family