Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C634
  Reference Plasmid   NZ_CP040085.1
  Reference Plasmid Size   23294
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0096149 HBPOFGEC_00016 14585 3 Skin 0.75 protein_coding synonymous_variant LOW 966T>C Asp322Asp
M0096150 HBPOFGEC_00016 14588 3 Skin 0.75 protein_coding synonymous_variant LOW 969A>G Thr323Thr
M0096151 HBPOFGEC_00016 14589 3 Skin 0.75 protein_coding missense_variant MODERATE 970G>A Val324Ile
M0096152 HBPOFGEC_00017 14745 3 Skin 0.75 protein_coding synonymous_variant LOW 189A>G Lys63Lys
M0096153 HBPOFGEC_00017 14854 3 Skin 0.75 protein_coding missense_variant MODERATE 80A>G Asn27Ser
M0096154 HBPOFGEC_00017 15047 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -114T>A None
M0096155 HBPOFGEC_00017 15096 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -163G>A None
M0096156 HBPOFGEC_00017 15270 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -337T>G None
M0096157 HBPOFGEC_00018 15659 3 Skin 0.75 protein_coding synonymous_variant LOW 1185C>T Ile395Ile
M0096158 HBPOFGEC_00018 15665 3 Skin 0.75 protein_coding synonymous_variant LOW 1179A>G Val393Val
M0096159 HBPOFGEC_00018 15833 3 Skin 0.75 protein_coding synonymous_variant LOW 1011G>T Pro337Pro
M0096160 HBPOFGEC_00018 15931 3 Skin 0.75 protein_coding synonymous_variant LOW 913C>T Leu305Leu
M0096161 HBPOFGEC_00018 16055 3 Skin 0.75 protein_coding synonymous_variant LOW 789A>C Leu263Leu
M0096162 HBPOFGEC_00018 16127 3 Skin 0.75 protein_coding synonymous_variant LOW 717T>C Ser239Ser
M0096163 HBPOFGEC_00018 16666 3 Skin 0.75 protein_coding missense_variant MODERATE 178A>G Thr60Ala
M0096164 HBPOFGEC_00017 17095 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -2162T>A None
M0096165 HBPOFGEC_00017 17099 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -2166A>C None
M0096166 HBPOFGEC_00017 17195 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -2262T>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
HBPOFGEC_00011 VFG037560 Csu fimbriae 100 1.8e-96 1 178 1.0 1 Biofilm Csu pilus major pilin subunit CsuA/B experiment
HBPOFGEC_00013 VFG037586 Csu fimbriae 100 2.6e-95 1 172 1.0 1 Biofilm Csu pilus subunit CsuB experiment
HBPOFGEC_00014 VFG037599 Csu fimbriae 100 1.3e-152 1 273 1.0 0.9856 Biofilm Csu pilus chaperone protein CsuC experiment
HBPOFGEC_00015 VFG037612 Csu fimbriae 100 0 1 832 1.0 1 Biofilm Csu pilus usher protein CsuD experiment
HBPOFGEC_00016 VFG037625 Csu fimbriae 99.4 3.4e-192 1 339 1.0 1 Biofilm Csu pilus tip adhesin CsuE experiment
HDCHHOMM_00011 VFG037560 Csu fimbriae 100 1.8e-96 1 178 1.0 1 Biofilm Csu pilus major pilin subunit CsuA/B experiment
HDCHHOMM_00013 VFG037586 Csu fimbriae 100 2.6e-95 1 172 1.0 1 Biofilm Csu pilus subunit CsuB experiment
HDCHHOMM_00014 VFG037599 Csu fimbriae 100 1.3e-152 1 273 1.0 0.9856 Biofilm Csu pilus chaperone protein CsuC experiment
HDCHHOMM_00015 VFG037612 Csu fimbriae 100 0 1 832 1.0 1 Biofilm Csu pilus usher protein CsuD experiment
HDCHHOMM_00016 VFG037625 Csu fimbriae 99.4 3.4e-192 1 339 1.0 1 Biofilm Csu pilus tip adhesin CsuE experiment
HBPOFGEC_00011 VFG037560 Csu fimbriae 100 1.4e-95 1 178 1.0 1 Biofilm Csu pilus major pilin subunit CsuA/B prediction
HBPOFGEC_00012 VFG037570 Csu fimbriae 100 3.8e-99 11 192 0.9479 1 Biofilm Csu pilus subunit CsuA prediction
HBPOFGEC_00013 VFG037586 Csu fimbriae 100 1.9e-94 1 172 1.0 1 Biofilm Csu pilus subunit CsuB prediction
HBPOFGEC_00014 VFG037599 Csu fimbriae 100 9.4e-152 1 273 1.0 0.9856 Biofilm Csu pilus chaperone protein CsuC prediction
HBPOFGEC_00015 VFG037612 Csu fimbriae 100 0 1 832 1.0 1 Biofilm Csu pilus usher protein CsuD prediction
HBPOFGEC_00016 VFG037628 Csu fimbriae 99.7 5.2e-192 1 339 1.0 1 Biofilm Csu pilus tip adhesin CsuE prediction
HDCHHOMM_00011 VFG037560 Csu fimbriae 100 1.4e-95 1 178 1.0 1 Biofilm Csu pilus major pilin subunit CsuA/B prediction
HDCHHOMM_00012 VFG037570 Csu fimbriae 100 3.8e-99 11 192 0.9479 1 Biofilm Csu pilus subunit CsuA prediction
HDCHHOMM_00013 VFG037586 Csu fimbriae 100 1.9e-94 1 172 1.0 1 Biofilm Csu pilus subunit CsuB prediction
HDCHHOMM_00014 VFG037599 Csu fimbriae 100 9.4e-152 1 273 1.0 0.9856 Biofilm Csu pilus chaperone protein CsuC prediction
HDCHHOMM_00015 VFG037612 Csu fimbriae 100 0 1 832 1.0 1 Biofilm Csu pilus usher protein CsuD prediction
HDCHHOMM_00016 VFG037628 Csu fimbriae 99.7 5.2e-192 1 339 1.0 1 Biofilm Csu pilus tip adhesin CsuE prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
HBPOFGEC_00015 1.B.11.6.1 99.5 0 1 832 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.11 The Outer Membrane Fimbrial Usher Porin (FUP) Family
HDCHHOMM_00015 1.B.11.6.1 99.5 0 1 832 1.0000 1.0000 1 Channels/Pores 1.B β-Barrel Porins 1.B.11 The Outer Membrane Fimbrial Usher Porin (FUP) Family