Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C649
  Reference Plasmid   NZ_CP041231.1
  Reference Plasmid Size   43703
  Reference Plasmid GC Content   0.32
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0170282 FMNIJLJH_00030 23932 4 Gut 0.24 protein_coding missense_variant MODERATE 1034A>G Asp345Gly
M0170283 FMNIJLJH_00030 24669 3 Gut 0.18 protein_coding missense_variant MODERATE 297T>G Asp99Glu
M0170284 FMNIJLJH_00001 69 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -96T>C None
M0170285 FMNIJLJH_00002 1117 3 Gut 0.18 protein_coding synonymous_variant LOW 291A>G Gln97Gln
M0170286 FMNIJLJH_00024 22695 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -3911A>T None
M0170287 FMNIJLJH_00030 24015 3 Gut 0.18 protein_coding synonymous_variant LOW 951T>C His317His
M0170288 FMNIJLJH_00022 20002 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -4273T>A None
M0170289 FMNIJLJH_00022 20057 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -4328A>G None
M0170290 FMNIJLJH_00022 20060 3 Gut 0.18 protein_coding upstream_gene_variant MODIFIER -4331C>T None
M0170291 FMNIJLJH_00027 21509 3 Gut 0.18 protein_coding missense_variant MODERATE 109A>G Ser37Gly
M0170292 FMNIJLJH_00013 14891 3 Gut 0.18 protein_coding downstream_gene_variant MODIFIER *4954A>G None
M0170293 FMNIJLJH_00013 14908 3 Gut 0.18 protein_coding downstream_gene_variant MODIFIER *4971C>T None
M0170294 FMNIJLJH_00014 15060 3 Gut 0.18 protein_coding downstream_gene_variant MODIFIER *4286A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
FMNIJLJH_00012 9.B.154.1.1 95.2 3.1e-84 1 167 1.0000 1.0000 9 Incompletely Characterized Transport Systems 9.B Putative transport proteins 9.B.154 The Putative Holin-2 (PH-2) Family