Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C662
  Reference Plasmid   NZ_CP043850.1
  Reference Plasmid Size   103715
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0097153 HNKDKBLJ_00082 73908 3 Skin 0.08 protein_coding synonymous_variant LOW 450C>T Gly150Gly
M0097154 HNKDKBLJ_00082 74091 4 Skin 0.11 protein_coding synonymous_variant LOW 267T>C Ile89Ile
M0097155 HNKDKBLJ_00082 74175 4 Skin 0.11 protein_coding synonymous_variant LOW 183G>C Ala61Ala
M0097156 HNKDKBLJ_00082 74210 3 Skin 0.08 protein_coding synonymous_variant LOW 148T>C Leu50Leu
M0097157 HNKDKBLJ_00082 74238 3 Skin 0.08 protein_coding missense_variant MODERATE 120G>C Met40Ile
M0097158 HNKDKBLJ_00082 74250 3 Skin 0.08 protein_coding synonymous_variant LOW 108T>C Val36Val
M0097159 HNKDKBLJ_00083 74380 3 Skin 0.08 protein_coding missense_variant MODERATE 364T>A Ser122Thr
M0097160 HNKDKBLJ_00082 74169 3 Skin 0.08 protein_coding synonymous_variant LOW 189C>G Gly63Gly
M0097161 HNKDKBLJ_00015 14000 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2396A>G None
M0097162 HNKDKBLJ_00022 16656 3 Skin 0.08 protein_coding synonymous_variant LOW 15T>C Ser5Ser
M0097163 HNKDKBLJ_00015 14237 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2633C>A None
M0097164 HNKDKBLJ_00015 14254 3 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -2650A>G None
M0097165 HNKDKBLJ_00020 14300 4 Skin 0.11 protein_coding synonymous_variant LOW 348C>T Asp116Asp
M0097166 HNKDKBLJ_00020 14321 4 Skin 0.11 protein_coding missense_variant MODERATE 327A>C Arg109Ser
M0097167 HNKDKBLJ_00020 14324 4 Skin 0.11 protein_coding synonymous_variant LOW 324C>T Leu108Leu
M0097168 HNKDKBLJ_00015 14701 4 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -3097G>A None
M0097169 HNKDKBLJ_00021 14907 4 Skin 0.11 protein_coding synonymous_variant LOW 162C>T Ile54Ile
M0097170 HNKDKBLJ_00021 14934 4 Skin 0.11 protein_coding synonymous_variant LOW 189C>G Ala63Ala
M0097171 HNKDKBLJ_00021 15142 3 Skin 0.08 protein_coding missense_variant MODERATE 397G>T Ala133Ser
M0097172 HNKDKBLJ_00020 14500 3 Skin 0.08 protein_coding missense_variant MODERATE 148G>A Val50Ile
M0097173 HNKDKBLJ_00020 14644 3 Skin 0.08 protein_coding missense_variant MODERATE 4C>T Arg2Trp
M0097174 HNKDKBLJ_00021 15520 3 Skin 0.08 protein_coding missense_variant MODERATE 775G>T Val259Leu
M0097175 HNKDKBLJ_00021 15621 3 Skin 0.08 protein_coding missense_variant MODERATE 876G>T Lys292Asn
M0097176 HNKDKBLJ_00021 15629 3 Skin 0.08 protein_coding missense_variant MODERATE 884G>A Gly295Asp
M0097177 HNKDKBLJ_00021 15630 3 Skin 0.08 protein_coding synonymous_variant LOW 885T>C Gly295Gly
M0097178 HNKDKBLJ_00021 15679 3 Skin 0.08 protein_coding missense_variant MODERATE 934A>G Ile312Val
M0097179 HNKDKBLJ_00021 16072 3 Skin 0.08 protein_coding missense_variant MODERATE 1327G>A Asp443Asn
M0097180 HNKDKBLJ_00084 75187 3 Skin 0.08 protein_coding missense_variant MODERATE 233A>G His78Arg
M0097181 HNKDKBLJ_00092 78846 3 Skin 0.08 protein_coding synonymous_variant LOW 180C>T Val60Val
M0097182 HNKDKBLJ_00092 79012 4 Skin 0.11 protein_coding missense_variant MODERATE 14A>C Asn5Thr
M0097183 HNKDKBLJ_00093 79069 3 Skin 0.08 protein_coding synonymous_variant LOW 1869T>C Ala623Ala
M0097184 HNKDKBLJ_00093 79081 3 Skin 0.08 protein_coding synonymous_variant LOW 1857T>C Leu619Leu
M0097185 HNKDKBLJ_00093 79357 3 Skin 0.08 protein_coding synonymous_variant LOW 1581T>G Ala527Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term