Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C676
  Reference Plasmid   NZ_CP046256.1
  Reference Plasmid Size   223979
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   conjugative





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0097271 GHCGNJOL_00084 94608 3 Skin 0.02 protein_coding upstream_gene_variant MODIFIER -2050T>C None
M0097272 GHCGNJOL_00084 94644 3 Skin 0.02 protein_coding upstream_gene_variant MODIFIER -2086G>T None
M0097273 GHCGNJOL_00089 94695 3 Skin 0.02 protein_coding missense_variant MODERATE 35C>A Ala12Glu
M0097274 GHCGNJOL_00089 94703 3 Skin 0.02 protein_coding missense_variant MODERATE 43C>G Pro15Ala
M0097275 GHCGNJOL_00089 94709 3 Skin 0.02 protein_coding missense_variant MODERATE 49C>T His17Tyr
M0097276 GHCGNJOL_00090 95041 3 Skin 0.02 protein_coding synonymous_variant LOW 966C>G Ala322Ala
M0097277 GHCGNJOL_00090 95307 4 Skin 0.03 protein_coding missense_variant MODERATE 700A>G Asn234Asp
M0097278 GHCGNJOL_00090 95414 4 Skin 0.03 protein_coding missense_variant MODERATE 593C>T Thr198Met
M0097279 GHCGNJOL_00090 95443 3 Skin 0.02 protein_coding synonymous_variant LOW 564T>C Gly188Gly
M0097280 GHCGNJOL_00090 95455 3 Skin 0.02 protein_coding synonymous_variant LOW 552G>A Lys184Lys
M0097281 GHCGNJOL_00090 95463 3 Skin 0.02 protein_coding missense_variant MODERATE 544A>T Thr182Ser
M0097282 GHCGNJOL_00090 95553 3 Skin 0.02 protein_coding synonymous_variant LOW 454A>C Arg152Arg
M0097283 GHCGNJOL_00090 95557 4 Skin 0.03 protein_coding synonymous_variant LOW 450A>G Ala150Ala
M0097284 GHCGNJOL_00090 95569 4 Skin 0.03 protein_coding synonymous_variant LOW 438A>G Glu146Glu
M0097285 GHCGNJOL_00090 95575 3 Skin 0.02 protein_coding synonymous_variant LOW 432C>T Ser144Ser
M0097286 GHCGNJOL_00090 95593 4 Skin 0.03 protein_coding synonymous_variant LOW 414G>T Arg138Arg
M0097287 GHCGNJOL_00090 95644 4 Skin 0.03 protein_coding synonymous_variant LOW 363C>A Ala121Ala
M0097288 GHCGNJOL_00090 95659 4 Skin 0.03 protein_coding synonymous_variant LOW 348C>G Arg116Arg
M0097289 GHCGNJOL_00090 95861 5 Skin 0.03 protein_coding missense_variant MODERATE 146A>C Glu49Ala
M0097290 GHCGNJOL_00090 95923 4 Skin 0.03 protein_coding synonymous_variant LOW 84T>C Ala28Ala
M0097291 GHCGNJOL_00084 96022 5 Skin 0.03 protein_coding upstream_gene_variant MODIFIER -3464T>C None
M0097292 GHCGNJOL_00221 216535 7 Skin 0.04 protein_coding missense_variant MODERATE 1132G>A Val378Ile
M0097293 GHCGNJOL_00189 181658 12 Skin 0.08 protein_coding synonymous_variant LOW 1164G>A Thr388Thr
M0097294 GHCGNJOL_00193 185983 3 Skin 0.02 protein_coding missense_variant MODERATE 283G>C Ala95Pro
M0097295 GHCGNJOL_00090 95890 3 Skin 0.02 protein_coding synonymous_variant LOW 117A>G Leu39Leu
M0097296 GHCGNJOL_00015 16548 3 Skin 0.02 protein_coding synonymous_variant LOW 192A>C Gly64Gly
M0097297 GHCGNJOL_00017 20524 4 Skin 0.03 protein_coding synonymous_variant LOW 957C>T Asn319Asn
M0097298 GHCGNJOL_00218 215384 3 Skin 0.02 protein_coding upstream_gene_variant MODIFIER -4874T>C None
M0097299 GHCGNJOL_00029 36294 3 Skin 0.02 protein_coding missense_variant MODERATE 362G>A Gly121Asp
M0097300 GHCGNJOL_00193 185715 3 Skin 0.02 protein_coding synonymous_variant LOW 15T>C Pro5Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
GHCGNJOL_00183 QGP81680.1|GH23 100 2.61e-231 1 321 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term