Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C683
  Reference Plasmid   NZ_CP047227.1
  Reference Plasmid Size   127800
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0097892 IOPCBLBK_00065 61025 6 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -4195C>A None
M0097893 IOPCBLBK_00065 61122 6 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -4292G>A None
M0097894 IOPCBLBK_00074 61198 5 Skin 0.06 protein_coding synonymous_variant LOW 12T>C Leu4Leu
M0097895 IOPCBLBK_00074 61213 6 Skin 0.07 protein_coding synonymous_variant LOW 27T>C Gly9Gly
M0097896 IOPCBLBK_00074 61300 4 Skin 0.05 protein_coding synonymous_variant LOW 114A>G Leu38Leu
M0097897 IOPCBLBK_00074 61303 4 Skin 0.05 protein_coding synonymous_variant LOW 117G>T Val39Val
M0097898 IOPCBLBK_00074 61361 4 Skin 0.05 protein_coding missense_variant MODERATE 175A>C Lys59Gln
M0097899 IOPCBLBK_00074 61384 5 Skin 0.06 protein_coding missense_variant MODERATE 198G>T Glu66Asp
M0097900 IOPCBLBK_00074 61401 4 Skin 0.05 protein_coding missense_variant MODERATE 215C>T Ala72Val
M0097901 IOPCBLBK_00074 61453 3 Skin 0.04 protein_coding synonymous_variant LOW 267T>C Val89Val
M0097902 IOPCBLBK_00074 61456 3 Skin 0.04 protein_coding synonymous_variant LOW 270A>T Ala90Ala
M0097903 IOPCBLBK_00074 61458 3 Skin 0.04 protein_coding missense_variant MODERATE 272G>A Gly91Glu
M0097904 IOPCBLBK_00074 61459 3 Skin 0.04 protein_coding synonymous_variant LOW 273A>G Gly91Gly
M0097905 IOPCBLBK_00074 61460 3 Skin 0.04 protein_coding missense_variant MODERATE 274A>T Asn92Tyr
M0097906 IOPCBLBK_00074 61461 3 Skin 0.04 protein_coding missense_variant MODERATE 275A>T Asn92Ile
M0097907 IOPCBLBK_00074 61465 3 Skin 0.04 protein_coding synonymous_variant LOW 279T>C Ile93Ile
M0097908 IOPCBLBK_00074 61481 4 Skin 0.05 protein_coding missense_variant MODERATE 295A>G Ile99Val
M0097909 IOPCBLBK_00074 61657 3 Skin 0.04 protein_coding synonymous_variant LOW 471C>T His157His
M0097910 IOPCBLBK_00074 61722 4 Skin 0.05 protein_coding missense_variant MODERATE 536G>A Arg179Gln
M0097911 IOPCBLBK_00074 61813 6 Skin 0.07 protein_coding synonymous_variant LOW 627C>A Pro209Pro
M0097912 IOPCBLBK_00074 61819 5 Skin 0.06 protein_coding synonymous_variant LOW 633T>G Pro211Pro
M0097913 IOPCBLBK_00074 61838 3 Skin 0.04 protein_coding synonymous_variant LOW 652C>T Leu218Leu
M0097914 IOPCBLBK_00075 62009 6 Skin 0.07 protein_coding missense_variant MODERATE 845C>T Ser282Leu
M0097915 IOPCBLBK_00075 62182 5 Skin 0.06 protein_coding missense_variant MODERATE 672G>T Met224Ile
M0097916 IOPCBLBK_00075 62461 3 Skin 0.04 protein_coding synonymous_variant LOW 393T>A Pro131Pro
M0097917 IOPCBLBK_00075 62467 3 Skin 0.04 protein_coding synonymous_variant LOW 387A>C Ile129Ile
M0097918 IOPCBLBK_00075 62469 3 Skin 0.04 protein_coding missense_variant MODERATE 385A>G Ile129Val
M0097919 IOPCBLBK_00075 62470 3 Skin 0.04 protein_coding synonymous_variant LOW 384G>A Lys128Lys
M0097920 IOPCBLBK_00075 62484 3 Skin 0.04 protein_coding missense_variant MODERATE 370T>C Trp124Arg
M0097921 IOPCBLBK_00075 62494 3 Skin 0.04 protein_coding synonymous_variant LOW 360T>G Val120Val
M0097922 IOPCBLBK_00075 62496 3 Skin 0.04 protein_coding missense_variant MODERATE 358G>A Val120Ile
M0097923 IOPCBLBK_00075 62497 3 Skin 0.04 protein_coding synonymous_variant LOW 357C>A Ala119Ala
M0097924 IOPCBLBK_00075 62500 3 Skin 0.04 protein_coding synonymous_variant LOW 354T>C Thr118Thr
M0097925 IOPCBLBK_00075 62551 3 Skin 0.04 protein_coding synonymous_variant LOW 303G>A Ser101Ser
M0097926 IOPCBLBK_00075 62553 3 Skin 0.04 protein_coding missense_variant MODERATE 301T>A Ser101Thr
M0097927 IOPCBLBK_00075 62560 3 Skin 0.04 protein_coding synonymous_variant LOW 294T>C Ala98Ala
M0097928 IOPCBLBK_00075 62584 4 Skin 0.05 protein_coding synonymous_variant LOW 270T>G Gly90Gly
M0097929 IOPCBLBK_00075 62596 3 Skin 0.04 protein_coding synonymous_variant LOW 258C>T Gly86Gly
M0097930 IOPCBLBK_00075 62605 3 Skin 0.04 protein_coding synonymous_variant LOW 249T>C Gly83Gly
M0097931 IOPCBLBK_00075 62620 3 Skin 0.04 protein_coding synonymous_variant LOW 234T>C Ile78Ile
M0097932 IOPCBLBK_00075 62625 4 Skin 0.05 protein_coding missense_variant MODERATE 229G>A Val77Ile
M0097933 IOPCBLBK_00075 62635 4 Skin 0.05 protein_coding synonymous_variant LOW 219T>C Asn73Asn
M0097934 IOPCBLBK_00075 62656 4 Skin 0.05 protein_coding synonymous_variant LOW 198A>C Ile66Ile
M0097935 IOPCBLBK_00075 62784 5 Skin 0.06 protein_coding missense_variant MODERATE 70T>C Phe24Leu
M0097936 IOPCBLBK_00075 62799 5 Skin 0.06 protein_coding missense_variant MODERATE 55A>G Ile19Val
M0097937 IOPCBLBK_00075 62834 3 Skin 0.04 protein_coding missense_variant MODERATE 20T>C Ile7Thr
M0097938 IOPCBLBK_00075 62835 3 Skin 0.04 protein_coding missense_variant MODERATE 19A>C Ile7Leu
M0097939 IOPCBLBK_00076 62990 4 Skin 0.05 protein_coding synonymous_variant LOW 15C>T Thr5Thr
M0097940 IOPCBLBK_00076 62995 4 Skin 0.05 protein_coding missense_variant MODERATE 20A>T Gln7Leu
M0097941 IOPCBLBK_00076 62996 4 Skin 0.05 protein_coding synonymous_variant LOW 21A>G Gln7Gln
M0097942 IOPCBLBK_00076 62999 4 Skin 0.05 protein_coding synonymous_variant LOW 24G>T Val8Val
M0097943 IOPCBLBK_00076 63002 4 Skin 0.05 protein_coding synonymous_variant LOW 27T>C Ile9Ile
M0097944 IOPCBLBK_00076 63004 5 Skin 0.06 protein_coding missense_variant MODERATE 29C>A Thr10Asn
M0097945 IOPCBLBK_00076 63005 4 Skin 0.05 protein_coding synonymous_variant LOW 30T>C Thr10Thr
M0097946 IOPCBLBK_00076 63008 4 Skin 0.05 protein_coding synonymous_variant LOW 33C>T His11His
M0097947 IOPCBLBK_00076 63062 3 Skin 0.04 protein_coding synonymous_variant LOW 87G>A Ala29Ala
M0097948 IOPCBLBK_00076 63068 3 Skin 0.04 protein_coding synonymous_variant LOW 93A>T Arg31Arg
M0097949 IOPCBLBK_00076 63072 3 Skin 0.04 protein_coding synonymous_variant LOW 97C>T Leu33Leu
M0097950 IOPCBLBK_00076 63098 9 Skin 0.11 protein_coding synonymous_variant LOW 123C>T Ala41Ala
M0097951 IOPCBLBK_00076 63104 9 Skin 0.11 protein_coding synonymous_variant LOW 129G>A Thr43Thr
M0097952 IOPCBLBK_00076 63128 4 Skin 0.05 protein_coding synonymous_variant LOW 153G>A Leu51Leu
M0097953 IOPCBLBK_00076 63186 9 Skin 0.11 protein_coding missense_variant MODERATE 211G>A Ala71Thr
M0097954 IOPCBLBK_00076 63212 8 Skin 0.10 protein_coding synonymous_variant LOW 237T>C Asp79Asp
M0097955 IOPCBLBK_00076 63227 8 Skin 0.10 protein_coding synonymous_variant LOW 252C>T Asn84Asn
M0097956 IOPCBLBK_00076 63236 9 Skin 0.11 protein_coding synonymous_variant LOW 261A>G Val87Val
M0097957 IOPCBLBK_00076 63275 5 Skin 0.06 protein_coding missense_variant MODERATE 300G>T Glu100Asp
M0097958 IOPCBLBK_00076 63284 6 Skin 0.07 protein_coding synonymous_variant LOW 309C>G Ala103Ala
M0097959 IOPCBLBK_00076 63326 9 Skin 0.11 protein_coding synonymous_variant LOW 351C>T Leu117Leu
M0097960 IOPCBLBK_00076 63383 10 Skin 0.12 protein_coding synonymous_variant LOW 408T>C Phe136Phe
M0097961 IOPCBLBK_00076 63392 10 Skin 0.12 protein_coding synonymous_variant LOW 417C>T Gly139Gly
M0097962 IOPCBLBK_00076 63500 9 Skin 0.11 protein_coding synonymous_variant LOW 525A>G Val175Val
M0097963 IOPCBLBK_00076 63563 10 Skin 0.12 protein_coding synonymous_variant LOW 588C>T Asp196Asp
M0097964 IOPCBLBK_00076 63566 4 Skin 0.05 protein_coding synonymous_variant LOW 591C>T Asp197Asp
M0097965 IOPCBLBK_00076 63704 9 Skin 0.11 protein_coding synonymous_variant LOW 729T>C Thr243Thr
M0097966 IOPCBLBK_00076 63714 5 Skin 0.06 protein_coding synonymous_variant LOW 739T>C Leu247Leu
M0097967 IOPCBLBK_00076 63765 3 Skin 0.04 protein_coding synonymous_variant LOW 790C>T Leu264Leu
M0097968 IOPCBLBK_00076 63773 3 Skin 0.04 protein_coding synonymous_variant LOW 798T>C Leu266Leu
M0097969 IOPCBLBK_00076 63782 4 Skin 0.05 protein_coding synonymous_variant LOW 807A>G Glu269Glu
M0097970 IOPCBLBK_00076 63827 4 Skin 0.05 protein_coding synonymous_variant LOW 852C>T Ile284Ile
M0097971 IOPCBLBK_00076 63836 8 Skin 0.10 protein_coding synonymous_variant LOW 861T>C Asn287Asn
M0097972 IOPCBLBK_00076 63949 5 Skin 0.06 protein_coding missense_variant MODERATE 974T>C Val325Ala
M0097973 IOPCBLBK_00076 63950 5 Skin 0.06 protein_coding synonymous_variant LOW 975C>G Val325Val
M0097974 IOPCBLBK_00076 63983 3 Skin 0.04 protein_coding synonymous_variant LOW 1008C>G Leu336Leu
M0097975 IOPCBLBK_00076 63989 6 Skin 0.07 protein_coding synonymous_variant LOW 1014C>T Asn338Asn
M0097976 IOPCBLBK_00076 64028 5 Skin 0.06 protein_coding synonymous_variant LOW 1053A>G Glu351Glu
M0097977 IOPCBLBK_00076 64031 5 Skin 0.06 protein_coding synonymous_variant LOW 1056A>T Ile352Ile
M0097978 IOPCBLBK_00076 64111 10 Skin 0.12 protein_coding missense_variant MODERATE 1136T>C Leu379Ser
M0097979 IOPCBLBK_00076 64128 6 Skin 0.07 protein_coding missense_variant MODERATE 1153T>A Leu385Ile
M0097980 IOPCBLBK_00076 64166 5 Skin 0.06 protein_coding synonymous_variant LOW 1191T>G Val397Val
M0097981 IOPCBLBK_00076 64220 4 Skin 0.05 protein_coding synonymous_variant LOW 1245T>C Asp415Asp
M0097982 IOPCBLBK_00076 64238 4 Skin 0.05 protein_coding synonymous_variant LOW 1263A>T Pro421Pro
M0097983 IOPCBLBK_00076 64286 9 Skin 0.11 protein_coding synonymous_variant LOW 1311C>G Leu437Leu
M0097984 IOPCBLBK_00076 64304 8 Skin 0.10 protein_coding synonymous_variant LOW 1329C>T Ser443Ser
M0097985 IOPCBLBK_00076 64309 10 Skin 0.12 protein_coding missense_variant MODERATE 1334G>C Gly445Ala
M0097986 IOPCBLBK_00069 64567 12 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -4903T>G None
M0097987 IOPCBLBK_00077 64649 5 Skin 0.06 protein_coding synonymous_variant LOW 45C>T Ile15Ile
M0097988 IOPCBLBK_00077 64667 6 Skin 0.07 protein_coding synonymous_variant LOW 63A>G Gly21Gly
M0097989 IOPCBLBK_00077 64781 3 Skin 0.04 protein_coding synonymous_variant LOW 177T>C His59His
M0097990 IOPCBLBK_00077 64796 3 Skin 0.04 protein_coding synonymous_variant LOW 192G>A Leu64Leu
M0097991 IOPCBLBK_00077 64801 3 Skin 0.04 protein_coding missense_variant MODERATE 197A>G Lys66Arg
M0097992 IOPCBLBK_00077 64863 14 Skin 0.17 protein_coding missense_variant MODERATE 259G>A Val87Ile
M0097993 IOPCBLBK_00077 65240 7 Skin 0.08 protein_coding synonymous_variant LOW 636G>A Gly212Gly
M0097994 IOPCBLBK_00077 65258 15 Skin 0.18 protein_coding synonymous_variant LOW 654C>T Tyr218Tyr
M0097995 IOPCBLBK_00077 65378 15 Skin 0.18 protein_coding synonymous_variant LOW 774C>T Tyr258Tyr
M0097996 IOPCBLBK_00077 65459 14 Skin 0.17 protein_coding synonymous_variant LOW 855G>A Lys285Lys
M0097997 IOPCBLBK_00078 65680 14 Skin 0.17 protein_coding missense_variant MODERATE 858C>G Asn286Lys
M0097998 IOPCBLBK_00078 65707 11 Skin 0.13 protein_coding synonymous_variant LOW 831A>C Ile277Ile
M0097999 IOPCBLBK_00078 65761 13 Skin 0.15 protein_coding synonymous_variant LOW 777T>C Gly259Gly
M0098000 IOPCBLBK_00078 65887 3 Skin 0.04 protein_coding missense_variant MODERATE 651T>A His217Gln
M0098001 IOPCBLBK_00078 66034 11 Skin 0.13 protein_coding synonymous_variant LOW 504G>A Thr168Thr
M0098002 IOPCBLBK_00078 66058 5 Skin 0.06 protein_coding synonymous_variant LOW 480G>A Ala160Ala
M0098003 IOPCBLBK_00078 66201 11 Skin 0.13 protein_coding missense_variant MODERATE 337C>G Pro113Ala
M0098004 IOPCBLBK_00078 66208 10 Skin 0.12 protein_coding synonymous_variant LOW 330T>C Asn110Asn
M0098005 IOPCBLBK_00078 66211 10 Skin 0.12 protein_coding synonymous_variant LOW 327A>G Glu109Glu
M0098006 IOPCBLBK_00078 66328 11 Skin 0.13 protein_coding synonymous_variant LOW 210T>C Ala70Ala
M0098007 IOPCBLBK_00078 66337 7 Skin 0.08 protein_coding synonymous_variant LOW 201C>T Leu67Leu
M0098008 IOPCBLBK_00078 66429 10 Skin 0.12 protein_coding missense_variant MODERATE 109T>A Leu37Met
M0098009 IOPCBLBK_00075 66538 10 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -3685C>T None
M0098010 IOPCBLBK_00075 66638 5 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -3785G>T None
M0098011 IOPCBLBK_00075 66651 9 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -3798A>G None
M0098012 IOPCBLBK_00075 66701 4 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -3848A>G None
M0098013 IOPCBLBK_00079 67460 3 Skin 0.04 protein_coding missense_variant MODERATE 730A>C Met244Leu
M0098014 IOPCBLBK_00067 57770 11 Skin 0.13 protein_coding missense_variant MODERATE 503C>T Thr168Ile
M0098015 IOPCBLBK_00062 58826 9 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4354G>T None
M0098016 IOPCBLBK_00062 58834 9 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4362T>C None
M0098017 IOPCBLBK_00062 58882 9 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4410G>A None
M0098018 IOPCBLBK_00069 58989 9 Skin 0.11 protein_coding missense_variant MODERATE 676A>G Lys226Glu
M0098019 IOPCBLBK_00069 58995 7 Skin 0.08 protein_coding missense_variant MODERATE 670G>A Gly224Ser
M0098020 IOPCBLBK_00069 59071 3 Skin 0.04 protein_coding missense_variant MODERATE 594G>C Glu198Asp
M0098021 IOPCBLBK_00069 59072 3 Skin 0.04 protein_coding missense_variant MODERATE 593A>C Glu198Ala
M0098022 IOPCBLBK_00069 59073 3 Skin 0.04 protein_coding stop_gained HIGH 592G>T Glu198*
M0098023 IOPCBLBK_00069 59077 3 Skin 0.04 protein_coding missense_variant MODERATE 588C>G Ser196Arg
M0098024 IOPCBLBK_00069 59078 3 Skin 0.04 protein_coding missense_variant MODERATE 587G>A Ser196Asn
M0098025 IOPCBLBK_00069 59079 3 Skin 0.04 protein_coding missense_variant MODERATE 586A>G Ser196Gly
M0098026 IOPCBLBK_00069 59083 3 Skin 0.04 protein_coding synonymous_variant LOW 582A>T Arg194Arg
M0098027 IOPCBLBK_00069 59089 3 Skin 0.04 protein_coding missense_variant MODERATE 576A>G Ile192Met
M0098028 IOPCBLBK_00069 59090 3 Skin 0.04 protein_coding missense_variant MODERATE 575T>C Ile192Thr
M0098029 IOPCBLBK_00069 59101 3 Skin 0.04 protein_coding missense_variant MODERATE 564C>A Asn188Lys
M0098030 IOPCBLBK_00069 59134 5 Skin 0.06 protein_coding synonymous_variant LOW 531C>T Ser177Ser
M0098031 IOPCBLBK_00069 59137 7 Skin 0.08 protein_coding missense_variant MODERATE 528G>T Glu176Asp
M0098032 IOPCBLBK_00069 59146 7 Skin 0.08 protein_coding synonymous_variant LOW 519T>C Ala173Ala
M0098033 IOPCBLBK_00069 59168 5 Skin 0.06 protein_coding missense_variant MODERATE 497C>T Ser166Phe
M0098034 IOPCBLBK_00069 59185 7 Skin 0.08 protein_coding synonymous_variant LOW 480G>A Val160Val
M0098035 IOPCBLBK_00069 59193 6 Skin 0.07 protein_coding synonymous_variant LOW 472T>C Leu158Leu
M0098036 IOPCBLBK_00069 59292 6 Skin 0.07 protein_coding missense_variant MODERATE 373C>A His125Asn
M0098037 IOPCBLBK_00069 59509 5 Skin 0.06 protein_coding synonymous_variant LOW 156C>T Pro52Pro
M0098038 IOPCBLBK_00069 59545 5 Skin 0.06 protein_coding synonymous_variant LOW 120A>G Arg40Arg
M0098039 IOPCBLBK_00069 59565 4 Skin 0.05 protein_coding missense_variant MODERATE 100G>C Glu34Gln
M0098040 IOPCBLBK_00069 59591 4 Skin 0.05 protein_coding missense_variant MODERATE 74C>T Pro25Leu
M0098041 IOPCBLBK_00070 59751 3 Skin 0.04 protein_coding stop_gained HIGH 190C>T Gln64*
M0098042 IOPCBLBK_00023 20992 5 Skin 0.06 protein_coding synonymous_variant LOW 1344A>C Val448Val
M0098043 IOPCBLBK_00023 21006 3 Skin 0.04 protein_coding missense_variant MODERATE 1330A>G Thr444Ala
M0098044 IOPCBLBK_00023 21190 4 Skin 0.05 protein_coding missense_variant MODERATE 1146T>A Asn382Lys
M0098045 IOPCBLBK_00065 60975 5 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -4145T>A None
M0098046 IOPCBLBK_00074 61225 3 Skin 0.04 protein_coding synonymous_variant LOW 39T>A Ala13Ala
M0098047 IOPCBLBK_00074 61229 3 Skin 0.04 protein_coding missense_variant MODERATE 43A>T Ser15Cys
M0098048 IOPCBLBK_00074 61230 3 Skin 0.04 protein_coding missense_variant MODERATE 44G>C Ser15Thr
M0098049 IOPCBLBK_00074 61231 3 Skin 0.04 protein_coding missense_variant MODERATE 45T>A Ser15Arg
M0098050 IOPCBLBK_00074 61232 3 Skin 0.04 protein_coding missense_variant MODERATE 46C>A Leu16Ile
M0098051 IOPCBLBK_00074 61234 3 Skin 0.04 protein_coding synonymous_variant LOW 48T>C Leu16Leu
M0098052 IOPCBLBK_00074 61236 3 Skin 0.04 protein_coding missense_variant MODERATE 50A>G Asn17Ser
M0098053 IOPCBLBK_00074 61510 3 Skin 0.04 protein_coding synonymous_variant LOW 324A>G Thr108Thr
M0098054 IOPCBLBK_00074 61513 3 Skin 0.04 protein_coding synonymous_variant LOW 327C>T Ala109Ala
M0098055 IOPCBLBK_00074 61514 3 Skin 0.04 protein_coding missense_variant MODERATE 328G>C Glu110Gln
M0098056 IOPCBLBK_00075 62021 3 Skin 0.04 protein_coding missense_variant MODERATE 833A>G Asn278Ser
M0098057 IOPCBLBK_00075 62224 3 Skin 0.04 protein_coding missense_variant MODERATE 630C>A Phe210Leu
M0098058 IOPCBLBK_00077 65170 3 Skin 0.04 protein_coding missense_variant MODERATE 566A>C Glu189Ala
M0098059 IOPCBLBK_00077 65489 12 Skin 0.14 protein_coding synonymous_variant LOW 885C>T Ala295Ala
M0098060 IOPCBLBK_00077 65537 3 Skin 0.04 protein_coding synonymous_variant LOW 933A>T Leu311Leu
M0098061 IOPCBLBK_00077 65539 3 Skin 0.04 protein_coding missense_variant MODERATE 935C>T Pro312Leu
M0098062 IOPCBLBK_00075 66694 4 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -3841T>C None
M0098063 IOPCBLBK_00061 53471 9 Skin 0.11 protein_coding stop_gained HIGH 97C>T Gln33*
M0098064 IOPCBLBK_00061 53488 9 Skin 0.11 protein_coding missense_variant MODERATE 80G>C Gly27Ala
M0098065 IOPCBLBK_00061 53525 9 Skin 0.11 protein_coding missense_variant MODERATE 43A>G Ile15Val
M0098066 IOPCBLBK_00061 53537 9 Skin 0.11 protein_coding missense_variant MODERATE 31G>A Asp11Asn
M0098067 IOPCBLBK_00061 53552 9 Skin 0.11 protein_coding missense_variant MODERATE 16G>C Ala6Pro
M0098068 IOPCBLBK_00062 53576 9 Skin 0.11 protein_coding synonymous_variant LOW 897G>A Lys299Lys
M0098069 IOPCBLBK_00062 53720 10 Skin 0.12 protein_coding missense_variant MODERATE 753G>A Met251Ile
M0098070 IOPCBLBK_00062 53723 10 Skin 0.12 protein_coding synonymous_variant LOW 750A>C Gly250Gly
M0098071 IOPCBLBK_00062 53801 10 Skin 0.12 protein_coding synonymous_variant LOW 672G>A Val224Val
M0098072 IOPCBLBK_00062 53837 11 Skin 0.13 protein_coding synonymous_variant LOW 636T>C Tyr212Tyr
M0098073 IOPCBLBK_00062 53852 10 Skin 0.12 protein_coding synonymous_variant LOW 621C>T Ala207Ala
M0098074 IOPCBLBK_00062 53873 10 Skin 0.12 protein_coding synonymous_variant LOW 600T>G Gly200Gly
M0098075 IOPCBLBK_00062 53887 10 Skin 0.12 protein_coding missense_variant MODERATE 586G>A Gly196Ser
M0098076 IOPCBLBK_00062 53974 10 Skin 0.12 protein_coding missense_variant MODERATE 499G>A Gly167Ser
M0098077 IOPCBLBK_00062 54089 10 Skin 0.12 protein_coding synonymous_variant LOW 384G>A Arg128Arg
M0098078 IOPCBLBK_00056 54483 8 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -4870A>G None
M0098079 IOPCBLBK_00056 54547 8 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -4934C>G None
M0098080 IOPCBLBK_00063 54634 8 Skin 0.10 protein_coding synonymous_variant LOW 6A>G Ser2Ser
M0098081 IOPCBLBK_00063 55087 10 Skin 0.12 protein_coding synonymous_variant LOW 459A>G Val153Val
M0098082 IOPCBLBK_00064 55541 7 Skin 0.08 protein_coding synonymous_variant LOW 84G>A Glu28Glu
M0098083 IOPCBLBK_00066 57321 9 Skin 0.11 protein_coding synonymous_variant LOW 72T>C Thr24Thr
M0098084 IOPCBLBK_00069 64514 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -4850G>A None
M0098085 IOPCBLBK_00077 65091 8 Skin 0.10 protein_coding missense_variant MODERATE 487G>A Ala163Thr
M0098086 IOPCBLBK_00076 63349 3 Skin 0.04 protein_coding missense_variant MODERATE 374A>G Lys125Arg
M0098087 IOPCBLBK_00076 63400 4 Skin 0.05 protein_coding missense_variant MODERATE 425A>G Asn142Ser
M0098088 IOPCBLBK_00076 63419 4 Skin 0.05 protein_coding synonymous_variant LOW 444G>A Pro148Pro
M0098089 IOPCBLBK_00076 63426 4 Skin 0.05 protein_coding missense_variant MODERATE 451C>G Gln151Glu
M0098090 IOPCBLBK_00076 63462 7 Skin 0.08 protein_coding missense_variant MODERATE 487A>T Met163Leu
M0098091 IOPCBLBK_00076 63467 4 Skin 0.05 protein_coding synonymous_variant LOW 492G>A Ala164Ala
M0098092 IOPCBLBK_00076 63479 6 Skin 0.07 protein_coding synonymous_variant LOW 504A>C Ala168Ala
M0098093 IOPCBLBK_00076 63483 6 Skin 0.07 protein_coding missense_variant MODERATE 508G>C Val170Leu
M0098094 IOPCBLBK_00076 63623 3 Skin 0.04 protein_coding synonymous_variant LOW 648T>C Gly216Gly
M0098095 IOPCBLBK_00076 63647 7 Skin 0.08 protein_coding synonymous_variant LOW 672T>G Val224Val
M0098096 IOPCBLBK_00076 63679 5 Skin 0.06 protein_coding missense_variant MODERATE 704G>A Ser235Asn
M0098097 IOPCBLBK_00076 63680 5 Skin 0.06 protein_coding synonymous_variant LOW 705T>C Ser235Ser
M0098098 IOPCBLBK_00076 63686 7 Skin 0.08 protein_coding synonymous_variant LOW 711C>T Arg237Arg
M0098099 IOPCBLBK_00076 63818 4 Skin 0.05 protein_coding synonymous_variant LOW 843G>A Arg281Arg
M0098100 IOPCBLBK_00076 63839 5 Skin 0.06 protein_coding synonymous_variant LOW 864C>T Asn288Asn
M0098101 IOPCBLBK_00076 64088 4 Skin 0.05 protein_coding missense_variant MODERATE 1113G>C Glu371Asp
M0098102 IOPCBLBK_00076 64101 3 Skin 0.04 protein_coding synonymous_variant LOW 1126C>T Leu376Leu
M0098103 IOPCBLBK_00076 64157 4 Skin 0.05 protein_coding synonymous_variant LOW 1182G>A Gly394Gly
M0098104 IOPCBLBK_00069 64570 7 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -4906T>A None
M0098105 IOPCBLBK_00077 64922 5 Skin 0.06 protein_coding synonymous_variant LOW 318T>A Ile106Ile
M0098106 IOPCBLBK_00077 65555 5 Skin 0.06 protein_coding synonymous_variant LOW 951A>G Val317Val
M0098107 IOPCBLBK_00023 21148 4 Skin 0.05 protein_coding synonymous_variant LOW 1188C>A Ala396Ala
M0098108 IOPCBLBK_00062 54220 5 Skin 0.06 protein_coding missense_variant MODERATE 253A>C Thr85Pro
M0098109 IOPCBLBK_00076 64266 6 Skin 0.07 protein_coding missense_variant MODERATE 1291G>A Asp431Asn
M0098110 IOPCBLBK_00076 64267 6 Skin 0.07 protein_coding missense_variant MODERATE 1292A>G Asp431Gly
M0098111 IOPCBLBK_00072 65613 6 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -4937T>G None
M0098112 IOPCBLBK_00078 65741 5 Skin 0.06 protein_coding missense_variant MODERATE 797C>T Thr266Ile
M0098113 IOPCBLBK_00078 65929 5 Skin 0.06 protein_coding synonymous_variant LOW 609T>C Asn203Asn
M0098114 IOPCBLBK_00078 66010 4 Skin 0.05 protein_coding synonymous_variant LOW 528C>T Pro176Pro
M0098115 IOPCBLBK_00079 66814 5 Skin 0.06 protein_coding synonymous_variant LOW 84C>T Thr28Thr
M0098116 IOPCBLBK_00096 83280 3 Skin 0.04 protein_coding missense_variant MODERATE 388T>C Ser130Pro
M0098117 IOPCBLBK_00078 65797 3 Skin 0.04 protein_coding synonymous_variant LOW 741G>A Leu247Leu
M0098118 IOPCBLBK_00023 21604 3 Skin 0.04 protein_coding synonymous_variant LOW 732T>C His244His
M0098119 IOPCBLBK_00073 60953 4 Skin 0.05 protein_coding missense_variant MODERATE 10C>A His4Asn
M0098120 IOPCBLBK_00065 60967 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -4137T>C None
M0098121 IOPCBLBK_00074 61297 3 Skin 0.04 protein_coding synonymous_variant LOW 111G>A Arg37Arg
M0098122 IOPCBLBK_00049 42946 3 Skin 0.04 protein_coding missense_variant MODERATE 446T>G Leu149Arg
M0098123 IOPCBLBK_00049 42980 3 Skin 0.04 protein_coding missense_variant MODERATE 412A>C Asn138His
M0098124 IOPCBLBK_00049 43056 3 Skin 0.04 protein_coding synonymous_variant LOW 336A>G Leu112Leu
M0098125 IOPCBLBK_00049 43080 3 Skin 0.04 protein_coding synonymous_variant LOW 312G>C Ala104Ala
M0098126 IOPCBLBK_00049 43371 3 Skin 0.04 protein_coding synonymous_variant LOW 21G>A Leu7Leu
M0098127 IOPCBLBK_00050 43486 4 Skin 0.05 protein_coding synonymous_variant LOW 319C>T Leu107Leu
M0098128 IOPCBLBK_00050 43613 3 Skin 0.04 protein_coding synonymous_variant LOW 192A>C Ile64Ile
M0098129 IOPCBLBK_00050 43670 3 Skin 0.04 protein_coding missense_variant MODERATE 135G>T Gln45His
M0098130 IOPCBLBK_00050 43724 3 Skin 0.04 protein_coding synonymous_variant LOW 81T>G Ala27Ala
M0098131 IOPCBLBK_00076 63181 5 Skin 0.06 protein_coding missense_variant MODERATE 206C>T Ser69Leu
M0098132 IOPCBLBK_00076 63188 5 Skin 0.06 protein_coding synonymous_variant LOW 213C>T Ala71Ala
M0098133 IOPCBLBK_00076 63195 5 Skin 0.06 protein_coding missense_variant MODERATE 220G>A Val74Ile
M0098134 IOPCBLBK_00076 63233 4 Skin 0.05 protein_coding synonymous_variant LOW 258C>T Asn86Asn
M0098135 IOPCBLBK_00076 63237 4 Skin 0.05 protein_coding synonymous_variant LOW 262T>C Leu88Leu
M0098136 IOPCBLBK_00076 63264 4 Skin 0.05 protein_coding synonymous_variant LOW 289T>C Leu97Leu
M0098137 IOPCBLBK_00076 63372 3 Skin 0.04 protein_coding missense_variant MODERATE 397C>T His133Tyr
M0098138 IOPCBLBK_00076 63373 3 Skin 0.04 protein_coding missense_variant MODERATE 398A>C His133Pro
M0098139 IOPCBLBK_00076 63432 3 Skin 0.04 protein_coding synonymous_variant LOW 457C>T Leu153Leu
M0098140 IOPCBLBK_00076 63497 4 Skin 0.05 protein_coding synonymous_variant LOW 522T>G Gly174Gly
M0098141 IOPCBLBK_00076 63503 4 Skin 0.05 protein_coding synonymous_variant LOW 528G>T Ser176Ser
M0098142 IOPCBLBK_00076 63540 4 Skin 0.05 protein_coding missense_variant MODERATE 565T>A Ser189Thr
M0098143 IOPCBLBK_00076 63542 4 Skin 0.05 protein_coding synonymous_variant LOW 567G>A Ser189Ser
M0098144 IOPCBLBK_00076 63596 4 Skin 0.05 protein_coding synonymous_variant LOW 621G>A Leu207Leu
M0098145 IOPCBLBK_00076 63599 4 Skin 0.05 protein_coding synonymous_variant LOW 624G>A Gln208Gln
M0098146 IOPCBLBK_00076 63645 4 Skin 0.05 protein_coding missense_variant MODERATE 670G>A Val224Ile
M0098147 IOPCBLBK_00076 63655 4 Skin 0.05 protein_coding missense_variant MODERATE 680C>A Ala227Glu
M0098148 IOPCBLBK_00076 63689 4 Skin 0.05 protein_coding synonymous_variant LOW 714G>T Pro238Pro
M0098149 IOPCBLBK_00076 63995 3 Skin 0.04 protein_coding synonymous_variant LOW 1020T>C Thr340Thr
M0098150 IOPCBLBK_00076 63998 3 Skin 0.04 protein_coding synonymous_variant LOW 1023T>C Cys341Cys
M0098151 IOPCBLBK_00076 64004 3 Skin 0.04 protein_coding synonymous_variant LOW 1029G>A Glu343Glu
M0098152 IOPCBLBK_00096 81286 3 Skin 0.04 protein_coding synonymous_variant LOW 2382T>C Tyr794Tyr
M0098153 IOPCBLBK_00049 43242 3 Skin 0.04 protein_coding synonymous_variant LOW 150T>C Ile50Ile
M0098154 IOPCBLBK_00050 43547 3 Skin 0.04 protein_coding synonymous_variant LOW 258G>A Arg86Arg
M0098155 IOPCBLBK_00078 66100 3 Skin 0.04 protein_coding synonymous_variant LOW 438G>A Leu146Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
IOPCBLBK_00123 VFG041098 SCI (Salmonella centrisome island)/SPI-6 T6SS 72.3 3.7e-219 17 499 0.966 0.9622 Effector delivery system EvpB family type VI secretion protein experiment
IOPCBLBK_00123 VFG041203 CTS1 75.3 7.3e-227 11 499 0.978 0.98 Effector delivery system type VI secretion system contractile sheath large subunit prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
IOPCBLBK_00122 PHI:7098 tssB-1 70.5 1.6e-60 11 166 0.8168 0.8764 eudicots fire blight T6SS-1 component unaffected pathogenicity
IOPCBLBK_00123 PHI:7099 tssC-1 78.3 1.5e-235 19 498 0.9600 0.9619 eudicots fire blight T6SS-1 component unaffected pathogenicity






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term