Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C684
  Reference Plasmid   NZ_CP047228.1
  Reference Plasmid Size   34071
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0098156 OBAMCNPB_00014 20491 5 Skin 0.18 protein_coding missense_variant MODERATE 2806T>G Ser936Ala
M0098157 OBAMCNPB_00017 22002 3 Skin 0.11 protein_coding missense_variant MODERATE 14T>C Val5Ala
M0098158 OBAMCNPB_00017 22009 3 Skin 0.11 protein_coding missense_variant MODERATE 7G>C Glu3Gln
M0098159 OBAMCNPB_00018 22116 3 Skin 0.11 protein_coding missense_variant MODERATE 31G>T Gly11Cys
M0098160 OBAMCNPB_00018 22126 3 Skin 0.11 protein_coding missense_variant MODERATE 41C>A Thr14Asn
M0098161 OBAMCNPB_00018 22146 3 Skin 0.11 protein_coding missense_variant MODERATE 61A>G Thr21Ala
M0098162 OBAMCNPB_00018 22164 3 Skin 0.11 protein_coding missense_variant MODERATE 79G>T Val27Leu
M0098163 OBAMCNPB_00018 22272 3 Skin 0.11 protein_coding stop_gained HIGH 187C>T Gln63*
M0098164 OBAMCNPB_00018 22494 3 Skin 0.11 protein_coding missense_variant MODERATE 409C>T Pro137Ser
M0098165 OBAMCNPB_00018 22509 3 Skin 0.11 protein_coding missense_variant MODERATE 424G>A Glu142Lys
M0098166 OBAMCNPB_00018 22519 3 Skin 0.11 protein_coding missense_variant MODERATE 434T>C Ile145Thr
M0098167 OBAMCNPB_00018 22521 3 Skin 0.11 protein_coding missense_variant MODERATE 436T>C Ser146Pro
M0098168 OBAMCNPB_00015 22840 6 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -1814G>C None
M0098169 OBAMCNPB_00019 22944 6 Skin 0.21 protein_coding synonymous_variant LOW 57C>T Ile19Ile
M0098170 OBAMCNPB_00019 23040 4 Skin 0.14 protein_coding synonymous_variant LOW 153G>A Leu51Leu
M0098171 OBAMCNPB_00019 23160 5 Skin 0.18 protein_coding synonymous_variant LOW 273T>C Tyr91Tyr
M0098172 OBAMCNPB_00019 23313 3 Skin 0.11 protein_coding synonymous_variant LOW 426C>T Tyr142Tyr
M0098173 OBAMCNPB_00019 23349 3 Skin 0.11 protein_coding synonymous_variant LOW 462T>C Tyr154Tyr
M0098174 OBAMCNPB_00017 26973 6 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4958C>T None
M0098175 OBAMCNPB_00020 27043 5 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -1135T>C None
M0098176 OBAMCNPB_00022 27664 3 Skin 0.11 protein_coding missense_variant MODERATE 311A>G Lys104Arg
M0098177 OBAMCNPB_00022 27680 3 Skin 0.11 protein_coding missense_variant MODERATE 295G>A Val99Ile
M0098178 OBAMCNPB_00022 27789 4 Skin 0.14 protein_coding synonymous_variant LOW 186A>G Leu62Leu
M0098179 OBAMCNPB_00022 27795 6 Skin 0.21 protein_coding synonymous_variant LOW 180G>A Glu60Glu
M0098180 OBAMCNPB_00023 27994 4 Skin 0.14 protein_coding synonymous_variant LOW 813A>T Val271Val
M0098181 OBAMCNPB_00023 28114 5 Skin 0.18 protein_coding synonymous_variant LOW 693G>A Ala231Ala
M0098182 OBAMCNPB_00023 28243 5 Skin 0.18 protein_coding synonymous_variant LOW 564C>A Gly188Gly
M0098183 OBAMCNPB_00023 28543 3 Skin 0.11 protein_coding synonymous_variant LOW 264A>G Gly88Gly
M0098184 OBAMCNPB_00023 28648 4 Skin 0.14 protein_coding synonymous_variant LOW 159T>C Ile53Ile
M0098185 OBAMCNPB_00023 28655 4 Skin 0.14 protein_coding missense_variant MODERATE 152T>C Ile51Thr
M0098186 OBAMCNPB_00020 28963 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -3055C>T None
M0098187 OBAMCNPB_00019 23571 3 Skin 0.11 protein_coding synonymous_variant LOW 684T>C Gly228Gly
M0098188 OBAMCNPB_00019 23599 3 Skin 0.11 protein_coding missense_variant MODERATE 712A>G Ser238Gly
M0098189 OBAMCNPB_00019 23641 3 Skin 0.11 protein_coding missense_variant MODERATE 754C>T Pro252Ser
M0098190 OBAMCNPB_00019 23897 6 Skin 0.21 protein_coding missense_variant MODERATE 1010G>A Arg337Lys
M0098191 OBAMCNPB_00017 26968 4 Skin 0.14 protein_coding upstream_gene_variant MODIFIER -4953G>A None
M0098192 OBAMCNPB_00023 28210 3 Skin 0.11 protein_coding synonymous_variant LOW 597A>C Leu199Leu
M0098193 OBAMCNPB_00007 12034 9 Skin 0.32 protein_coding stop_lost&splice_region_variant HIGH 727T>C Ter243Glnext*?
M0098194 OBAMCNPB_00009 14553 4 Skin 0.14 protein_coding missense_variant MODERATE 667C>T Pro223Ser
M0098195 OBAMCNPB_00006 15251 6 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -3226A>G None
M0098196 OBAMCNPB_00014 18095 10 Skin 0.36 protein_coding missense_variant MODERATE 410T>C Val137Ala
M0098197 OBAMCNPB_00014 19013 5 Skin 0.18 protein_coding missense_variant MODERATE 1328A>G Lys443Arg
M0098198 OBAMCNPB_00003 6731 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -99G>A None
M0098199 OBAMCNPB_00003 7195 3 Skin 0.11 protein_coding synonymous_variant LOW 366C>T Arg122Arg
M0098200 OBAMCNPB_00004 8129 3 Skin 0.11 protein_coding synonymous_variant LOW 705G>T Ala235Ala
M0098201 OBAMCNPB_00005 10826 3 Skin 0.11 protein_coding missense_variant MODERATE 445T>C Tyr149His
M0098202 OBAMCNPB_00005 11072 3 Skin 0.11 protein_coding missense_variant MODERATE 691A>G Ser231Gly
M0098203 OBAMCNPB_00005 11194 3 Skin 0.11 protein_coding synonymous_variant LOW 813T>C Arg271Arg
M0098204 OBAMCNPB_00007 12358 3 Skin 0.11 protein_coding stop_gained HIGH 403G>T Glu135*






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
OBAMCNPB_00009 Mercury (Hg) 81.5 1.5e-250 1 540 1.0389 1.0000 experiment
OBAMCNPB_00010 Mercury (Hg) 71.4 2.4e-31 1 91 1.0000 1.0000 experiment
OBAMCNPB_00011 Mercury (Hg) 86.2 6.2e-56 1 116 1.0000 1.0000 experiment
OBAMCNPB_00012 Mercury (Hg) 85.8 1.3e-62 1 134 0.9926 0.9306 experiment
OBAMCNPB_00008 Mercury (Hg), Phenylmercury Acetate [class: Organo-mercury] 100 8.7e-118 1 211 1.0000 1.0000 prediction
OBAMCNPB_00009 Mercury (Hg), Phenylmercury Acetate [class: Organo-mercury] 100 7.5e-299 1 540 1.0000 1.0000 prediction
OBAMCNPB_00010 Mercury (Hg) 100 5.5e-37 8 91 0.9231 1.0000 prediction
OBAMCNPB_00011 Mercury (Hg) 100 4.1e-61 1 116 1.0000 1.0000 prediction
OBAMCNPB_00012 Mercury (Hg) 100 2.7e-72 1 135 1.0000 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
OBAMCNPB_00010 1.A.72.3.1 71.4 2.6e-29 1 91 1.0000 1.0000 1 Channels/Pores 1.A α-Type Channels 1.A.72 The Mercuric Ion Pore (Mer) Superfamily
OBAMCNPB_00011 1.A.72.3.1 80.2 4.5e-50 1 116 1.0000 1.2747 1 Channels/Pores 1.A α-Type Channels 1.A.72 The Mercuric Ion Pore (Mer) Superfamily