Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C701
  Reference Plasmid   NZ_CP049094.1
  Reference Plasmid Size   18550
  Reference Plasmid GC Content   0.30
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0098694 KHGLGANF_00006 9999 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4517C>T None
M0098695 KHGLGANF_00006 10008 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4526T>C None
M0098696 KHGLGANF_00006 10046 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4564G>A None
M0098697 KHGLGANF_00006 10103 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4621C>T None
M0098698 KHGLGANF_00015 10128 3 Skin 0.21 protein_coding missense_variant MODERATE 1150A>G Ile384Val
M0098699 KHGLGANF_00015 10682 3 Skin 0.21 protein_coding missense_variant MODERATE 596C>T Ser199Leu
M0098700 KHGLGANF_00015 10888 3 Skin 0.21 protein_coding synonymous_variant LOW 390G>A Lys130Lys
M0098701 KHGLGANF_00015 10894 3 Skin 0.21 protein_coding synonymous_variant LOW 384T>C Gly128Gly
M0098702 KHGLGANF_00015 11165 3 Skin 0.21 protein_coding missense_variant MODERATE 113G>A Arg38Lys
M0098703 KHGLGANF_00010 11605 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4079A>G None
M0098704 KHGLGANF_00010 11643 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4117C>T None
M0098705 KHGLGANF_00015 15579 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4302G>A None
M0098706 KHGLGANF_00022 15679 3 Skin 0.21 protein_coding synonymous_variant LOW 69A>G Leu23Leu
M0098707 KHGLGANF_00022 15696 3 Skin 0.21 protein_coding missense_variant MODERATE 86G>A Arg29Lys
M0098708 KHGLGANF_00022 15708 3 Skin 0.21 protein_coding missense_variant MODERATE 98G>A Arg33Lys
M0098709 KHGLGANF_00022 15709 3 Skin 0.21 protein_coding synonymous_variant LOW 99G>A Arg33Arg
M0098710 KHGLGANF_00022 15712 3 Skin 0.21 protein_coding synonymous_variant LOW 102A>G Lys34Lys
M0098711 KHGLGANF_00022 16040 3 Skin 0.21 protein_coding synonymous_variant LOW 430C>T Leu144Leu
M0098712 KHGLGANF_00022 16094 3 Skin 0.21 protein_coding missense_variant MODERATE 484T>G Ser162Ala
M0098713 KHGLGANF_00022 16186 3 Skin 0.21 protein_coding synonymous_variant LOW 576T>A Ile192Ile
M0098714 KHGLGANF_00022 16195 4 Skin 0.29 protein_coding synonymous_variant LOW 585T>C Asp195Asp
M0098715 KHGLGANF_00015 16238 4 Skin 0.29 protein_coding upstream_gene_variant MODIFIER -4961G>A None
M0098716 KHGLGANF_00015 16244 3 Skin 0.21 protein_coding upstream_gene_variant MODIFIER -4967A>G None
M0098717 KHGLGANF_00023 16387 4 Skin 0.29 protein_coding synonymous_variant LOW 141C>T Ile47Ile
M0098718 KHGLGANF_00023 16498 4 Skin 0.29 protein_coding missense_variant MODERATE 252T>G Asp84Glu
M0098719 KHGLGANF_00023 16517 4 Skin 0.29 protein_coding missense_variant MODERATE 271A>G Lys91Glu
M0098720 KHGLGANF_00023 16560 4 Skin 0.29 protein_coding missense_variant MODERATE 314A>G Lys105Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group
KHGLGANF_00022 Cadmium (Cd), Zinc (Zn) 93.7 2.9e-101 1 205 1.0000 1.0000 experiment
KHGLGANF_00022 Cadmium (Cd), Zinc (Zn) 100 1e-102 1 205 1.0000 1.0000 prediction






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
KHGLGANF_00022 2.A.77.1.1 93.2 2.4e-99 1 205 1.0000 0.9809 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.77 The Cadmium Resistance (CadD) Family