Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C703
  Reference Plasmid   NZ_CP049229.1
  Reference Plasmid Size   111803
  Reference Plasmid GC Content   0.31
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0142826 FNHOGKAB_00069 71817 3 Vaginal 0.38 protein_coding synonymous_variant LOW 237A>T Ser79Ser
M0142827 FNHOGKAB_00074 79796 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1377G>T Ser459Ser
M0142828 FNHOGKAB_00074 79857 3 Vaginal 0.38 protein_coding missense_variant MODERATE 1316A>C Asn439Thr
M0142829 FNHOGKAB_00074 79861 3 Vaginal 0.38 protein_coding missense_variant MODERATE 1312C>A Leu438Ile
M0142830 FNHOGKAB_00074 79868 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1305C>T Ser435Ser
M0142831 FNHOGKAB_00074 79874 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1299G>A Leu433Leu
M0142832 FNHOGKAB_00074 79901 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1272A>C Ser424Ser
M0142833 FNHOGKAB_00074 79904 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1269A>G Gln423Gln
M0142834 FNHOGKAB_00074 79955 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1218C>T Asp406Asp
M0142835 FNHOGKAB_00074 79976 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1197C>T Gly399Gly
M0142836 FNHOGKAB_00074 80015 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1158G>A Thr386Thr
M0142837 FNHOGKAB_00074 80020 3 Vaginal 0.38 protein_coding missense_variant MODERATE 1153T>C Ser385Pro
M0142838 FNHOGKAB_00074 80030 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1143T>C Tyr381Tyr
M0142839 FNHOGKAB_00074 80069 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1104T>C Ser368Ser
M0142840 FNHOGKAB_00074 80087 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1086C>T Asp362Asp
M0142841 FNHOGKAB_00074 80099 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1074T>A Ala358Ala
M0142842 FNHOGKAB_00074 80120 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1053C>G Val351Val
M0142843 FNHOGKAB_00074 80198 3 Vaginal 0.38 protein_coding missense_variant MODERATE 975A>G Ile325Met
M0142844 FNHOGKAB_00074 80246 3 Vaginal 0.38 protein_coding synonymous_variant LOW 927A>G Leu309Leu
M0142845 FNHOGKAB_00074 80249 3 Vaginal 0.38 protein_coding synonymous_variant LOW 924A>G Lys308Lys
M0142846 FNHOGKAB_00074 80264 3 Vaginal 0.38 protein_coding synonymous_variant LOW 909A>G Gln303Gln
M0142847 FNHOGKAB_00074 80272 3 Vaginal 0.38 protein_coding missense_variant MODERATE 901A>C Ile301Leu
M0142848 FNHOGKAB_00074 80290 3 Vaginal 0.38 protein_coding synonymous_variant LOW 883T>C Leu295Leu
M0142849 FNHOGKAB_00074 80316 3 Vaginal 0.38 protein_coding missense_variant MODERATE 857T>C Ile286Thr
M0142850 FNHOGKAB_00074 80321 3 Vaginal 0.38 protein_coding missense_variant MODERATE 852C>G Asn284Lys
M0142851 FNHOGKAB_00074 80435 3 Vaginal 0.38 protein_coding synonymous_variant LOW 738A>G Gln246Gln
M0142852 FNHOGKAB_00074 80750 3 Vaginal 0.38 protein_coding synonymous_variant LOW 423T>C Ile141Ile
M0142853 FNHOGKAB_00074 80801 3 Vaginal 0.38 protein_coding synonymous_variant LOW 372A>G Gln124Gln
M0142854 FNHOGKAB_00071 81779 3 Vaginal 0.38 protein_coding upstream_gene_variant MODIFIER -4760A>G None
M0142855 FNHOGKAB_00075 82284 3 Vaginal 0.38 protein_coding synonymous_variant LOW 264G>A Lys88Lys
M0142856 FNHOGKAB_00075 82393 3 Vaginal 0.38 protein_coding synonymous_variant LOW 373T>C Leu125Leu
M0142857 FNHOGKAB_00076 84630 3 Vaginal 0.38 protein_coding synonymous_variant LOW 969G>T Leu323Leu
M0142858 FNHOGKAB_00076 84690 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1029G>A Gln343Gln
M0142859 FNHOGKAB_00076 84709 3 Vaginal 0.38 protein_coding missense_variant MODERATE 1048G>A Ala350Thr
M0142860 FNHOGKAB_00076 84726 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1065T>C Tyr355Tyr
M0142861 FNHOGKAB_00076 84839 3 Vaginal 0.38 protein_coding missense_variant MODERATE 1178C>A Ala393Asp
M0142862 FNHOGKAB_00077 86195 3 Vaginal 0.38 protein_coding missense_variant MODERATE 17G>A Arg6Lys
M0142863 FNHOGKAB_00078 86291 3 Vaginal 0.38 protein_coding synonymous_variant LOW 426C>T Ser142Ser
M0142864 FNHOGKAB_00078 86336 3 Vaginal 0.38 protein_coding synonymous_variant LOW 381A>G Pro127Pro
M0142865 FNHOGKAB_00078 86408 3 Vaginal 0.38 protein_coding synonymous_variant LOW 309T>C Ala103Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
FNHOGKAB_00041 QIH24470.1|CBM50 100 1.21e-138 1 202 1 1
FNHOGKAB_00057 QIH24483.1|CBM50 99.7 2.17e-201 1 287 1 0.9441
FNHOGKAB_00074 QIH24498.1|GT51 100 0 1 700 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term